Claims
- 1. A method for delivering a medicament to an individual comprising the steps of:
providing a product that includes a gum base center and a coating that substantially surrounds the center, the coating comprising at least 50% by weight of the product, the coating including a medicament; chewing the product to cause the medicament to be released from the product into the buccal cavity of the individual; and continuing to chew the product thereby creating a fluid pressure causing the medicament to enter the systemic system of the individual through an oral mucosa of the individual.
- 2. The method of claim 1 wherein the coating includes a high-intensity sweetener.
- 3. The method of claim 1 wherein the high-intensity sweetener is chosen from the group consisting of aspartame, sucralose, saccharin, and acesulfame-k.
- 4. The method of claim 1 wherein the coating is produced by alternating layers of a powder and a syrup onto the gum base center.
- 5. The method of claim 1 wherein the medicament is chosen from the group consisting of: analgesics; muscle relaxants; antibiotics; antivirals; antihistamines; decongestants; anti-inflammatories; antacids; anesthetics; antifungal agents; antimicrobial agents; cancer therapies; antimycotics; oral contraceptives; diuretics; antitussives; nutraceuticals; probiotics; bioengineered pharmaceuticals; oral vaccines; hormones; psychotherapeutic agents; insulin; vitamins; minerals; and cardiovascular agents.
- 6. The method of claim 1 wherein the coating has a matte finish.
- 7. The method of claim 1 wherein the coating does not include a shellac layer.
- 8. A product comprising:
a chewable water insoluble center; and a coating including a medicament that surrounds the center, the coating comprising at least 50% by weight of the product.
- 9. The product of claim 8 wherein the medicament is chosen from the group consisting of: analgesics; muscle relaxants; antibiotics; antivirals; stimulants; antihistamines; decongestants; anti-inflammatories; antacids; anesthetics; antifungal agents; antimicrobial agents; cancer therapies; antimycotics; oral contraceptives; diuretics; antitussives; nutraceuticals; probiotics; bioengineered pharmaceuticals; oral vaccines; hormones; psychotherapeutic agents; insulin; vitamins; minerals; and cardiovascular agents.
- 10. The product of claim 8 wherein the coating includes a sufficient amount of taste masking agent to provide acceptable organoleptic properties.
- 11. The product of claim 10 wherein the taste masking agent is chosen from the group consisting of: zinc gluconate, ethyl maltol, glycine, acesulfame-k, aspartame; saccharin; fructose; xylitol; isomalt; maltitol; spray dried licorice root; glycerrhizine; sodium gluconate; glucono delta-lactone; ethyl vanillin; dextrose; sucralose; vanillin; and ethyl maltol.
- 12. The product of claim 10 wherein the taste masking agent comprises approximately 30% to about 99% by weight of the coating.
- 13. The product of claim 8 wherein the coating includes approximately 0.5% to about 5% by weight of a high-intensity sweetener chosen from the group consisting of aspartame, sucralose, saccharine, and acesulfame-k.
- 14. The product of claim 8 wherein the coating does not have a shellac layer.
- 15. A chewable product including a medicament comprising:
a center consisting of ingredients chosen from the group consisting of elastomers, resins, fats, oils, softners, and inorganic fillers,; and a coating that at least substantially surrounds the center and includes a medicament.
- 16. The product of claim 15 wherein the medicament is chosen from the group consisting of: analgesics; muscle relaxants; antibiotics; antivirals; stimulants; antihistamines; decongestants; anti-inflammatories; antacids; anesthetics; antifungal agents; antimicrobial agents; cancer therapies; antimycotics; oral contraceptives; diuretics; antitussives; nutraceuticals; probiotics; bioengineered pharmaceuticals; oral vaccines; hormones; psychotherapeutic agents; insulin; vitamins; minerals; and cardiovascular agents.
- 17. The product of claim 15 wherein the coating includes a sufficient amount of taste masking agent to provide acceptable organoleptic properties.
- 18. The product of claim 15 wherein the taste masking agent is chosen from the group consisting of: zinc gluconate, ethyl maltol, glycine, acesulfame-k, aspartame; saccharin; fructose; xylitol; isomalt; maltitol; spray dried licorice root; glycerrhizine; sodium gluconate; glucono delta-lactone; ethyl vanillin; dextrose; sucralose; vanillin; and ethyl maltol.
- 19. The product of claim 15 wherein the taste masking agent comprises approximately 30% to about 99% by weight of the coating.
- 20. The product of claim 15 wherein the coating includes approximately 0.5% to about 5% by weight of a high-intensity sweetener chosen from the group consisting of aspartame, sucralose, saccharine, and acesulfame-k.
- 21. The product of claim 15 wherein the coating comprises at least 70% by weight powder when it is applied to the gum center.
- 22. The product of claim 15 wherein the coating comprises approximately 50 to about 75% by weight of the product.
- 23. The product of claim 15 wherein the coating does not have a shellac layer.
- 24. A method for reducing the amount of agent necessary to achieve an effect in an individual as compared a typical agent that is swallowed comprising the steps of:
providing a product including a gum base center and a coating that substantially surrounds the gum base center, the coating including an agent that is typically swallowed by an individual to achieve a specific effect, the product including less than the typical amount of agent that is swallowed by the individual to achieve the effect; chewing the product and thereby causing the agent to be released into the salvia of the individual; and continuing to chew the product forcing the agent through an oral mucosa contained in a buccal cavity of the individual.
- 25. The method of claim 24 wherein the agent is a medicament.
- 26. The method of claim 24 wherein the medicament is chosen from the group consisting of: analgesics; muscle relaxants; antibiotics; antivirals; antihistamines; decongestants; anti-inflammatories; antacids; anesthetics; antifungal agents; antimicrobial agents; cancer therapies; antimycotics; oral contraceptives; diuretics; antitussives; nutraceuticals; probiotics; bioengineered pharmaceuticals; oral vaccines; hormones; psychotherapeutic agents; and cardiovascular agents.
- 27. The method of claim 24 wherein the agent is a stimulant.
- 28. A method of enhancing an individual's performance comprising the steps of:
providing a product having a chewable water insoluble center and a coating that substantially surrounds the center, the coating comprising at least 50% by weight of the product, the coating including a performance enhancing amount of caffeine; and chewing the product to enhance the performance.
- 29. The method of claim 28 wherein the performance to be enhanced is athletic.
- 30. The method of claim 29 wherein the performance to be enhanced is cognitive.
- 31. The method of claim 29 wherein the performance to be enhanced is alertness.
- 32. The method of claim 29 wherein the chewing gum is chewed ten minutes or less before the performance.
- 33. A method of delivering a medicament comprising the steps of:
providing a product having a center, the center consisting of a chewable water insoluble portion and the product including a coating that substantially surrounds the center, the coating including a medicament; and chewing the product to cause the medicament to be released into a buccal cavity of an individual chewing the chewing gum.
- 34. The method of claim 33 wherein the medicament is chosen from the group consisting of: analgesics; muscle relaxants; antibiotics; antivirals; antihistamines; decongestants; anti-inflammatories; antacids; anesthetics; antifungal agents; antimicrobial agents; cancer therapies; antimycotics; oral contraceptives; diuretics; antitussives; nutraceuticals; probiotics; bioengineered pharmaceuticals; oral vaccines; hormones; psychotherapeutic agents; and cardiovascular agents.
- 35. The method of claim 33 wherein the coating includes a masking agent.
- 36. The method of claim 33 wherein the coating comprises at least 50% by weight of the product.
- 37. The method of claim 36 wherein a sufficient amount of the maksing agent is used to provide acceptable organoleptic properties to the product.
- 38. A method for delivering a medicament to an individual comprising the steps of:
providing a product that includes a gum base center that is substantially coated by a formulation that includes a medicament and a sufficient amount of a masking agent to provide acceptable organoleptic properties, only the coating including water soluble components; and chewing the product to cause the medicament to be released from the formulation into a buccal cavity of the individual.
- 39. The method of claim 38 wherein the medicament is chosen from the group consisting of: analgesics; muscle relaxants; antibiotics; antivirals; stimulants; antihistamines; decongestants; anti-inflammatories; antacids; anesthetics; antifungal agents; antimicrobial agents; cancer therapies; antimycotics; oral contraceptives; diuretics; antitussives; nutraceuticals; probiotics; bioengineered pharmaceuticals; oral vaccines; hormones; psychotherapeutic agents; insulin; vitamins; minerals; and cardiovascular agents.
- 40. The method of claim 38 wherein the taste masking agent is chosen from the group consisting of: zinc gluconate, ethyl maltol, glycine, acesulfame-k, aspartame; saccharin; fructose; xylitol; isomalt; maltitol; spray dried licorice root; glycerrhizine; sodium gluconate; glucono delta-lactone; vanillin; dextrose; sucralose; and ethyl maltol.
- 41. The method of claim 38 wherein the masking agent comprises approximately 30% to about 99% by weight of the coating.
- 42. A method of manufacturing a medicament containing product comprising the steps of:
preparing a center consisting essentially of water insoluble components; and coating the center by placing layers of a powder and a syrup on the center to create a coated product, at least one of the powder or syrup layers including a medicament; and the coated product comprising at least 50% by weight syrup and powder coating.
- 43. The method of claim 42 wherein the coating includes a high-intensity sweetener.
- 44. The method of claim 42 wherein the medicament is chosen from the group consisting of: analgesics; muscle relaxants; antibiotics; antivirals; antihistamines; decongestants; anti-inflammatories; antacids; anesthetics; antifungal agents; antimicrobial agents; cancer therapies; antimycotics; oral contraceptives; diuretics; antitussives; nutraceuticals; probiotics; bioengineered pharmaceuticals; oral vaccines; hormones; psychotherapeutic agents; insulin; vitamins; minerals; and cardiovascular agents.
- 45. The method of claim 44 wherein the powder comprises at least 70% by weight of the coating.
- 46. The method of claim 44 wherein the coating does not include a shellac layer.
Priority Claims (1)
Number |
Date |
Country |
Kind |
PCT/US99/29742 |
Dec 1999 |
WO |
|
CROSS REFERENCE TO RELATED APPLICATIONS
[0001] This is a continuation-in-part of U.S. patent application No. 09/510,878, filed on Feb. 23, 2000, which is a continuation-in-part of U.S. patent application Ser. No. 09/286,818, filed on Apr. 6, 1999 and PCT Patent Application No. PCT/US99/29742 filed on Dec. 14, 1999.
Continuation in Parts (2)
|
Number |
Date |
Country |
Parent |
09510878 |
Feb 2000 |
US |
Child |
09992122 |
Nov 2001 |
US |
Parent |
09286818 |
Apr 1999 |
US |
Child |
09510878 |
Feb 2000 |
US |