Package for medicine

Information

  • Patent Grant
  • 8251219
  • Patent Number
    8,251,219
  • Date Filed
    Monday, October 22, 2007
    17 years ago
  • Date Issued
    Tuesday, August 28, 2012
    12 years ago
  • Inventors
  • Original Assignees
  • Examiners
    • Pickett; J. Gregory
    • Collins; Raven
    Agents
    • Kowalik, Walgreen Co.; Francis C.
    • Marshall, Gerstein & Borun LLP
    • Rueth; Randall G.
Abstract
A new package for medicine has an extended base section that has a generally planar top surface. A series of separate receptacles with frusto-conical walls are positioned across the base section. The receptacles are not integral with (or adhered to) the base section. Instead, each of the receptacles is nested in one of a series of apertures in the base section. Each receptacle has a flange that extends outwardly from and surrounds the opening on the receptacle. The flange has a top surface that is wider than the aperture in which the receptacle is nested, preventing the receptacle from falling through the aperture. A flexible, removable top sheet is sealed to a part of the top surface of the base section, sealing the medicine within the walls of the receptacles and preventing the receptacles from being lifted out of the aperture until the top sheet is peeled back. The top sheet may be adhered to the base section along lines of adhesion that surround each of the openings. Perforations in the top sheet enable individual receptacles to be exposed and removed from the base section without exposing other receptacles.
Description
BACKGROUND OF THE INVENTION

The present invention relates generally to packages for medicine, and more particularly to packages in which individual doses of prescription or non-prescription medicine are contained in separate receptacles. (The term “medicine” is used broadly in this document, and is intended to encompass things such as vitamin or nutritional supplements, etc.)


“Blister” packs have been known for many years. Examples can be found, for example, in U.S. Pat. Nos. 2,973,087; 3,811,564; and 4,159,771. U.S. Pat. No. 4,946,038 shows a medicine container in which a single dose of medicine is contained in a tray that has a cover sheet that can be peeled away.


Both U.S. Pat. No. 5,163,5590 and U.S. Pat. No. 7,097,037 show a container that has multiple receptacles in which single doses can be stored. Each receptacle has its own cover that can be peeled away.


BRIEF SUMMARY

The applicants have developed a new package for medicine. Like prior known devices, the package has an extended base section that has a planar top surface. A series of separate receptacles are positioned across the base section. A flexible, removable top sheet is sealed to a part of the top surface of the base section, sealing the medicine within the walls of the receptacles.


Unlike in prior known packages, the receptacles in the new package are not integral with (or adhered to) the base section. Instead, each of the receptacles is nested in one of a series of apertures in the base section. Each receptacle has a flange that extends outwardly from and surrounds the opening on the receptacle. The flange has a planar top surface that is wider than the aperture in which the receptacle is nested, preventing the receptacle from falling through the aperture. Each receptacle is held to the base section by the top sheet, which prevents the receptacle from being lifted out of the aperture until the top sheet is peeled back.


The wall of each receptacle is shaped so that all cross-sections of the receptacle below the opening fit within the aperture in which the receptacle is nested. This configuration permits the receptacle to be easily lifted through the aperture when the top sheet is peeled back. The wall on a receptacle may, for example, be a frusto-conical wall.


The top sheet may be adhered to the base section along lines of adhesion that surround each of the openings. Perforations can be provided in the top sheet, between the lines of adhesion surrounding openings on adjacent receptacles. These perforations enable individual receptacles to be exposed and removed from the base section without exposing other receptacles. Corresponding perforations can also be provided in the base section, between adjacent apertures.


The removable top sheet can be adhered to the top surfaces of the flanges of the receptacles. Adhering the top sheet along the entire circumference of a flange can assure that liquid contents from the receptacle will not spill through the aperture in the base section.





BRIEF DESCRIPTION OF THE DRAWINGS

The invention may be better understood by referring to the accompanying drawings, in which:



FIGS. 1-4 are perspective views of one embodiment of a package that uses the invention, showing the package in various stages of use.



FIG. 5 is a perspective view of the base section of the package of FIG. 1.



FIG. 6 is a front view of another embodiment of a package that uses the invention.



FIG. 7 is a side view of the package of FIG. 6.



FIG. 8 is a front view of another embodiment of a package that uses the invention.



FIG. 9 is an enlarged perspective view of the receptacle used in the package of FIGS. 1-4.



FIG. 10 is an enlarged perspective view of a portion of the base section and receptacles of the package of FIGS. 1-4, with the top sheet removed.





DETAILED DESCRIPTION

The package 10 seen in FIGS. 1-4 has three primary components: an extended base section 12, a series of separate receptacles 14, and a removable top sheet 16. Medicine 18, such as pills or tablets, is stored in the receptacles. The medicine can be removed by peeling back the top sheet (FIG. 2), lifting the receptacle from the base section (FIGS. 3 and 4), and then removing the medicine from the receptacle. For example, the receptacle could be used as a cup. Each of these primary components of the package will be discussed in more detail below.


The Base Section


The base section 12, best seen in FIG. 5, serves as a base for the package. It is a generally planar element that has a series of apertures 22 that are used to hold the receptacles. In the illustrated example, the base section is made of thin cardboard. Preferably, the base section has a planar top surface, but some unevenness of the top surface is possible. For example, recesses could be provided around the apertures to accommodate flanges on the receptacles.


In some cases, it may be desirable to provide fold lines in the base section 12. Fold lines enable the base section to be folded for more convenient storage. In the example seen in FIGS. 6 and 7, a package 10 can be folded at two pairs of fold lines 24, 26 so that receptacles 14a on one part 28 of the base section fit between receptacles 14b on another part 30 of the base section. This kind of arrangement (where the distance between one fold line and its nearest row of apertures differs from the distance between the adjacent fold line and its nearest row of apertures) can provide a particularly compact, folded package useful for storage or travel.


The apertures 22 can be arranged in a variety of two-dimensional patterns across the base section 12. The size and shape of the apertures corresponds with the size and shape of the receptacles, which will be discussed below. In the example in FIGS. 1-5, the apertures are circular in cross section, and are arranged in a two-dimensional grid pattern in the base section. Other arrangements are possible. For example, the apertures could be triangular, rectangular (with or without rounded corners), oblong, or even irregular in cross section. Instead of a regular grid, the pattern could have staggered rows, or even a radial or spiral arrangement.


It will often be preferred for all the apertures 22 on the base section 12 to be the same size and shape, but this may not always be necessary or preferred. The packages seen in FIGS. 6-8 are arranged so that some receptacles hold a single pill or tablet (such as a kind of pill 34 that is to be taken at relatively short intervals), while other receptacles hold a group of pills or tablets (the group including the same kind of pill held in the other receptacle plus another kind of pill 36 that is taken less frequently). When the size or number of pills to be stored in the receptacles will vary, it might, in some circumstances, be desirable to provide receptacles of different sizes or shapes. If receptacles of different sizes or shapes are to be used, then it might be preferred for the sizes or shapes of the apertures to vary, too.


The base section 12 may have perforations 40 between adjacent apertures 22. Perforations make it easier to separate the base section into separate segments, which might be convenient when the user is traveling. In the embodiment of the invention seen in FIGS. 1-4, the perforations are evenly spaced across the length and width of the base section, and pass between each aperture and every adjacent aperture. Alternatively, perforations could be used to divide the base section only into parallel strips. For example, where an individual should be taking medicine several times each day, the base section could be divided by perforations so that each strip includes a full day's worth of doses. This kind of arrangement is illustrated in FIG. 8.


The Receptacles


As stated above, the receptacles 14 are used to hold medicine. Accordingly, they are sized and shaped appropriately. If it is contemplated that the package 10 will be used with a particular kind of medicine (for example, an individual pill having a given shape, or a specific group of pills), then it might be desirable for the receptacles to be configured to facilitate the storage of that particular kind of medicine in each receptacle (and the removal of that kind of medicine from the receptacle). If the package is intended to be used with a variety of different possible kinds of medicine (for example, one set of pills for one customer, and a different set of pills for a different customer), then it might be desirable for the receptacles to be configured to facilitate the storage of a wide range of different possible kinds of medicine.


As better seen in FIG. 9, the illustrated receptacles 14 have a wall 50 and a bottom 52 that define a space in which the medicine can be stored. Access is provided through an opening 54 at the top. In the illustrated example, the receptacle is made of plastic, and the wall is a frusto-conical wall that extends downwardly and inwardly from the opening on the receptacle. Other materials and shapes are possible. For example, a hemispherical wall (with no separate bottom) might also be used. It is preferred that all cross sections of the receptacle below the opening fit within the aperture 22 in which the receptacle is nested. In the examples illustrated in FIGS. 1-4, all cross sections of the receptacle below the top opening 54 are circles, and each of those circles has a diameter that is less than the diameter of the aperture in which the receptacle is nested. This allows the receptacle to be easily lifted through the aperture.


The receptacles 14 are nested in the apertures 22, but not adhered to the base section 12. In other words, there is no fastening mechanism that prevents a user from easily lifting the receptacles away from the base section once the top sheet 16 is removed. As a result, even after removal from the base section, the receptacles may be used as a convenient holder for the medicine until it is used. While it might generally be preferred that there be no resistance whatsoever to the receptacles being separated from the base section after the top sheet is removed, in some cases the receptacles might be lightly tacked to base section. A lightly tacked receptacle is not “adhered,” as that term is used here, because light tacking does not prevent the user from easily removing the receptacle once the top sheet is removed.


When it is in place, the flexible top sheet 16 prevents the receptacles 14 from being lifted upwardly from the base section 12. Other structure might be desired to prevent the receptacles (or their contents) from slipping downwardly through the apertures 22. The receptacle 14 illustrated in FIG. 9 has an annular flange 60 that serves this function. The flange should be wide enough so that the overall width of the receptacle 14 at its opening 54 is wider than the aperture in which the receptacle is nested. The illustrated flange extends outwardly from and completely surrounds the opening on the receptacle and has an outside diameter that is wider than and exceeds the diameter of the aperture in which the receptacle is nested. Other arrangements are possible. For example, in some circumstances it may not be necessary for the flange to extend all the way around the opening. To prevent the receptacle from falling through the aperture, it may sometimes be enough for flange sections to extend from only one side of the opening, or from only a few points on the opening.


The width of the flange 60 (or flange sections) may vary. In the example seen in FIGS. 1-4 and 10, the flanges do not extend more than half way between adjacent apertures 22. This arrangement prevents the flanges from overlapping each other, and leaves an exposed portion 64 on the upper surface of the base section 12. This will be discussed in more detail below.


The Top Sheet


The illustrated removable top sheet 16 is flexible and made from metal or plastic foil. It is adhered to the top surface of the flanges 60 of each of the receptacles 14 and to the exposed portion 64 of the top surface of the base section 12. The illustrated top sheet is adhered to the base section along of lines of adhesion 66. Adhering the top sheet to the base section is important to hold the receptacles to the base section. While in some circumstances it might be sufficient to seal the top sheet to only the periphery of the base section, providing interior sealing locations (such as along the illustrated lines of adhesion) keeps the top sheet close to the base section, helping to assure that the receptacles do not unintentionally dislodge from the apertures before the top sheet is removed. In this example, the lines of adhesion are close to and completely surround each receptacle 14, but in some circumstances close lines of adhesion might go only part way around the aperture.


In the example seen in FIGS. 1-4, the top sheet 16 covers all of the base section 12. In other examples, such as those seen in FIGS. 6 and 8, the top sheet may cover only part of the base section. Other parts of the base section could be covered, for example, with printed material such as patient information.


The illustrated top sheet 16 is not only adhered to the base section 12 but is also secured to the top surface 62 of the flanges 60 of the receptacles 14. This helps to ensure that the medicine contained in the receptacles does not inadvertently spill from the receptacles before the top sheet is removed. Such spillage might be a concern if the medicine is a small pill or a liquid. Even more protection against spillage might be obtained by using a separate removable cover over some or all of the receptacles, under the top sheet.


In these examples, the top sheet 16 is sealed to the top surface 62 of the flange 60 all the way around the opening 54 of the receptacle 14. While this arrangement may often be preferred (particularly, for example, if no separate cover is provided and the package 10 is used to store liquid medicine), in some circumstances it may be preferred to seal the top sheet to only portions of the flange.


This description of various embodiments of the invention has been provided for illustrative purposes. Revisions or modifications may be apparent to those of ordinary skill in the art, and do not necessarily depart from the invention. The full scope of the invention is set forth in the following claims.

Claims
  • 1. A package for medicine that has: an extended base section;a generally planar top surface on the base section;a plurality of apertures in the base section;a removable top sheet that is sealed to a planar part of the top surface of the base section;a series of separate receptacles that are nested in the apertures and held to the base section by the top sheet without any structure that prevents a user from easily removing the receptacles from the base section once the top sheet is removed;an opening on top on each of the receptacles;a wall on each of the receptacles that extends downwardly from the opening on the receptacle, has an uncovered portion that extends beneath the lowermost edge of the base section, and is shaped so that all cross sections of the receptacle below the opening fit within the aperture in which the receptacle is nested; anda flange section on each of the receptacles that extends outwardly from the opening so that the overall width of the receptacle at its opening is wider than the aperture in which the receptacle is nested.
  • 2. A package as recited in claim 1, in which the removable top sheet is flexible.
  • 3. A package as recited in claim 1, in which the top sheet has perforations between adjacent apertures.
  • 4. A package as recited in claim 1, in which the top sheet is adhered directly to the base section along separate sets of lines of adhesion that surround each aperture.
  • 5. A package as recited in claim 1, in which: the top sheet is adhered directly to the base section along separate sets of lines of adhesion that surround each aperture; andthe top sheet has perforations between the lines of adhesion between adjacent apertures.
  • 6. A package as recited in claim 1, in which both the base section and the top sheet have perforations between adjacent apertures.
  • 7. A package as recited in claim 1, in which the removable top sheet is adhered to the top surface of the flange sections of at least one of the receptacles.
  • 8. A package as recited in claim 1, in which the removable top sheet is adhered to the flange sections of each of the receptacles.
  • 9. A package of medicine a recited in claim 1, in which the wall on the receptacles is a frusto-conical shaped wall.
  • 10. A package of medicine that has: an extended base section;a generally planar top surface on the base section;a plurality of apertures in the base section;a series of separate receptacles that are nested in the apertures but not adhered or sealed to the base section;an opening on top of each of the receptacles;a wall on each of the receptacles that extends downwardly from the opening on the receptacle, has an uncovered side portion that extends beneath the lowermost edge of the base section, and is shaped so that all cross-sections of the receptacle below the opening fit within the aperture in which the receptacle is nested;a flange section on each of the receptacles that extends outwardly from the opening on the receptacle so that the overall width of the receptacle at its opening is wider than the aperture in which the receptacle is nested;exposed portions on the base section that extend between the apertures and are uncovered by the flange sections of the receptacles;a removable top sheet that is sealed to the exposed sections on the base section between the receptacles and to a planar part of the top surface of the base section, holding the receptacles to the base section, andmedicine sealed within the walls of the receptacles.
  • 11. A package as recited in claim 10, in which the base section is folded on at least one fold line.
  • 12. A package of light-weight medical pills or tablets that has: an extended base section;a generally planar top surface on the base section;a plurality of circular apertures arranged in a two-dimensional pattern in the base section;perforations in the base section between adjacent apertures;a removable top sheet that is flexible and is sealed to the top surface of the flanges of the receptacles and to exposed portions on the base that extend between the apertures and are uncovered by the flange sections of the receptacles a part of the top surface of the base section;a series of separate receptacles that are nested in the apertures and held to the base section by the top sheet without any other structure that prevents a user from easily removing the receptacles from the base section once the top sheet is removed;a circular opening on top of each of the receptacles;a frusto-conical wall on each of the receptacles that extends downwardly and inwardly from the opening on the receptacle and has an uncovered side portion that extends beneath the lowermost edge of the base section; andan annular flange on each of the receptacles that surrounds the opening on the receptacle and has an outside diameter that exceeds the diameter of the aperture in which the receptacle is nested.
  • 13. A package for medicine as recited in claim 10, in which: the base section is planar.
  • 14. A package for medicine as recited in claim 1, in which: the separate receptacles are held to the base section by the top sheet without any seal or adhesion of the receptacles to the base section once the top sheet is removed.
  • 15. A package of medicine as recited in claim 12, in which: the separate receptacles are held to the base section by the top sheet without any seal or adhesion of the receptacles to the base section once the top sheet is removed.
US Referenced Citations (168)
Number Name Date Kind
2973087 Rohdin Feb 1961 A
3069273 Wayne Dec 1962 A
3135455 Santangelo Jun 1964 A
3279596 Prym et al. Oct 1966 A
3283885 Grunewald et al. Nov 1966 A
3305077 Greif et al. Feb 1967 A
3324995 Sharp, Jr. Jun 1967 A
3351192 La Plante Nov 1967 A
3414414 Christine et al. Dec 1968 A
3503493 Nagy Mar 1970 A
3529718 Zaremski Sep 1970 A
3659706 Serrell May 1972 A
3660960 Inman May 1972 A
3737029 Serrell et al. Jun 1973 A
3743084 Douglas Jul 1973 A
3780856 Braverman Dec 1973 A
3809221 Compere May 1974 A
3811564 Braber May 1974 A
3817393 Neilsen Jun 1974 A
3856144 Kelly Dec 1974 A
3921804 Tester Nov 1975 A
3924748 Braverman Dec 1975 A
4120399 Clarke Oct 1978 A
4159771 Komatsu et al. Jul 1979 A
4192425 Landau et al. Mar 1980 A
4196809 Tonrey Apr 1980 A
4211329 Braverman Jul 1980 A
4295567 Knudsen et al. Oct 1981 A
4305502 Gregory et al. Dec 1981 A
4340141 Fischer Jul 1982 A
4364549 Komossa et al. Dec 1982 A
4384649 Brodsky May 1983 A
4428709 Peters Jan 1984 A
4437579 Obland Mar 1984 A
4673086 Braverman et al. Jun 1987 A
4790440 Leszczak Dec 1988 A
4803048 Nason Feb 1989 A
4844246 Harrison et al. Jul 1989 A
4860899 McKee Aug 1989 A
4889236 Bartell et al. Dec 1989 A
4889238 Batchelor Dec 1989 A
4909414 Heath Mar 1990 A
4946038 Eaton Aug 1990 A
4955481 Novinski et al. Sep 1990 A
4975015 Harding Dec 1990 A
4989733 Patry Feb 1991 A
5009894 Hsiao Apr 1991 A
5014851 Wick May 1991 A
5044498 Galiegue et al. Sep 1991 A
5050739 Hannan et al. Sep 1991 A
5163559 Bunin Nov 1992 A
5209354 Thornhill et al. May 1993 A
5232907 Matsuhiro et al. Aug 1993 A
5259503 Steingraber, Jr. Nov 1993 A
5265728 Allendorf et al. Nov 1993 A
5323907 Kalvelage Jun 1994 A
5377836 Eisenbraun Jan 1995 A
5390796 Kerfoot, Jr. Feb 1995 A
5431283 Weinstein et al. Jul 1995 A
5460471 Connor et al. Oct 1995 A
5509773 Connor et al. Apr 1996 A
5515972 Shames May 1996 A
5549204 Toren et al. Aug 1996 A
5564593 East, Sr. Oct 1996 A
RE35445 Pora Feb 1997 E
5685420 Martin et al. Nov 1997 A
5720384 Wu-Chen Feb 1998 A
5740717 Sowden et al. Apr 1998 A
5775505 Vasquez et al. Jul 1998 A
5788079 Bouthiette et al. Aug 1998 A
5836615 Elliot et al. Nov 1998 A
5915559 Hulick et al. Jun 1999 A
5954202 Mellon Sep 1999 A
6021623 Bouthiette et al. Feb 2000 A
6023916 Bouthiette et al. Feb 2000 A
6024222 Friberg et al. Feb 2000 A
6024247 Birr et al. Feb 2000 A
6155423 Katzner et al. Dec 2000 A
6206233 Schulze Mar 2001 B1
6219997 Friberg et al. Apr 2001 B1
6244462 Ehrensvard et al. Jun 2001 B1
6318051 Preiss et al. Nov 2001 B1
6349831 Buss Feb 2002 B1
6382412 Wood May 2002 B1
6382420 Bouthiette et al. May 2002 B1
6412636 Jones et al. Jul 2002 B1
6491211 Evans et al. Dec 2002 B1
6499595 Petricca Dec 2002 B1
6520329 Fuchs et al. Feb 2003 B1
6523686 Bae Feb 2003 B1
6543616 Peterson Apr 2003 B1
6550618 Peterson Apr 2003 B2
6557740 Dent May 2003 B1
6628199 Ehrensvard et al. Sep 2003 B1
6648140 Petricca Nov 2003 B2
6652215 Parker et al. Nov 2003 B1
6679376 Chen Jan 2004 B2
6681935 Lewis Jan 2004 B1
6698425 Widerstrom et al. Mar 2004 B1
6708826 Ginsberg et al. Mar 2004 B1
6752272 Jones et al. Jun 2004 B2
6776288 Kopecky Aug 2004 B2
6802422 Kalvelage et al. Oct 2004 B2
6848580 Paliotta et al. Feb 2005 B2
6951282 Jones Oct 2005 B2
6964338 Kancsar et al. Nov 2005 B2
6978894 Mundt Dec 2005 B2
6981592 Siegel Jan 2006 B2
6997320 Kancsar et al. Feb 2006 B1
6997344 Brown et al. Feb 2006 B2
7000768 Morita et al. Feb 2006 B2
7025207 Breu et al. Apr 2006 B2
7055294 Lewis Jun 2006 B1
7063211 Williams-Hartman Jun 2006 B2
7090079 Ehrlund et al. Aug 2006 B2
7097037 Keffeler et al. Aug 2006 B1
7126879 Snyder Oct 2006 B2
7188728 Williams-Hartman Mar 2007 B2
7188729 DeJonge Mar 2007 B2
7308984 Bouthiette et al. Dec 2007 B2
7336564 Feodoroff et al. Feb 2008 B2
20020045184 Chen Apr 2002 A1
20020104773 Kalvelage et al. Aug 2002 A1
20020134694 Cherng Sep 2002 A1
20020197098 Palmer Dec 2002 A1
20030031595 Kirchhevel et al. Feb 2003 A1
20030032190 Brown et al. Feb 2003 A1
20030034271 Burridge Feb 2003 A1
20040026293 Hughes Feb 2004 A1
20040069675 Stevens Apr 2004 A1
20040108240 Ragot Jun 2004 A1
20040188315 Morita et al. Sep 2004 A1
20050051454 Coe et al. Mar 2005 A1
20050082194 Fry et al. Apr 2005 A1
20050102838 Leason May 2005 A1
20050109658 Bindford May 2005 A1
20050112194 Gervais et al. May 2005 A1
20050173291 Specker et al. Aug 2005 A1
20050178692 Chang Aug 2005 A1
20050210682 Bartholin Sep 2005 A1
20050238415 Busam et al. Oct 2005 A1
20050256830 Siegel et al. Nov 2005 A1
20050269238 Reape et al. Dec 2005 A1
20050274643 Arnold Dec 2005 A1
20050274644 Williams-Hartman Dec 2005 A1
20060021900 Feodoroff Feb 2006 A1
20060042987 Buss Mar 2006 A1
20060060597 Stevens Mar 2006 A1
20060144749 Arnold et al. Jul 2006 A1
20060249420 Hession Nov 2006 A1
20060289328 Hession Dec 2006 A1
20070023317 Brozell et al. Feb 2007 A1
20070045149 Hession Mar 2007 A1
20070048413 Glydon Mar 2007 A1
20070056876 Jones Mar 2007 A1
20070084746 Udo et al. Apr 2007 A1
20070084747 Gherdan et al. Apr 2007 A1
20070125679 Smith Jun 2007 A1
20070205131 Bouthiette Sep 2007 A1
20070205132 Bouthiette Sep 2007 A1
20070205133 Valentine et al. Sep 2007 A1
20070284280 Young Dec 2007 A1
20080023366 Bouthiette Jan 2008 A1
20080110791 Specker May 2008 A1
20080265011 Specker Oct 2008 A1
20080289989 Kalvelage et al. Nov 2008 A1
20090078051 Twerdochlib et al. Mar 2009 A1
20090242451 Kessler Oct 2009 A1
Foreign Referenced Citations (23)
Number Date Country
2 629 458 Oct 2009 CA
4429503 Feb 1996 DE
1 270 441 Jan 2003 EP
1 505 017 Feb 2005 EP
1 505 018 Feb 2005 EP
1 884 360 Feb 2008 EP
1 930 251 Jun 2008 EP
1 964 788 Sep 2008 EP
1 985 544 Oct 2008 EP
2 090 525 Aug 2009 EP
2 112 078 Oct 2009 EP
2750403 Jan 1998 FR
WO-9856704 Dec 1998 WO
WO-03053794 Jul 2003 WO
WO-03076303 Sep 2003 WO
WO-03089333 Oct 2003 WO
WO-2004103857 Dec 2004 WO
WO-2005023672 Mar 2005 WO
WO-2005110864 Nov 2005 WO
WO-2005110889 Nov 2005 WO
WO-2005110890 Nov 2005 WO
WO-2007046126 Apr 2007 WO
WO-2009078051 Jun 2009 WO