Claims
- 1. A dispensing and applicator system for applying a plurality of dermatological agents, comprising:
- (a) a flexible, moisture impermeable support sheet;
- (b) a plurality of applicator pads affixed in a separated array to the surface of said support sheet; each of said pads being impregnated with a composition comprising a different dermatological agent; and
- (c) a flexible, moisture-impermeable cover sheet having its peripheral surface releasably sealed to the opposed peripheral surface of the support sheet so as to form a compartment containing said pads and defined by a continuous seal, which seal is positioned inwardly from the edges of the sheets over a portion of the opposed peripheral surfaces, so as to form two opposed flanges, and wherein the cover sheet and the support sheet are also releasably sealed together between said pads to divide the compartment into a plurality of subcompartments, each containing one of said pads; the flanges being separable to at least partially release the cover sheet from the support sheet, so that said pads are exposed.
- 2. The dispensing and applicator system according to claim 1, wherein the cover sheet is scored along lines between said pads, so that the flanges abutting one subcompartment are separable so that the cover sheet tears along said score lines of the cover sheet and separates from the support sheet to open one subcompartment and expose one of said pads, while the other subcompartments remain intact.
- 3. The dispensing and applicator system according to claim 1, wherein the support sheet is scored along lines between said pads, so that the flanges abutting one subcompartment are separable so that the support sheet tears along said score lines of the support sheet and separates from the cover sheet to open one subcompartment and expose one of said pads, while the other subcompartments remain intact.
- 4. The dispensing and applicator system according to claim 1, wherein the cover sheet and the support sheet are made of a deformable plastic coated foil.
- 5. The dispensing and applicator system according to claim 1, wherein the cover sheet and the support sheet are sealed together by heat sealing or by an adhesive.
- 6. The dispensing and applicator system according to claim 1, wherein the applicator pads are made of synthetic fiber, natural fiber, or foam.
- 7. The dispensing and applicator system according to claim 1, wherein a first applicator pad impregnated with a first composition comprising a first dermatological agent and a second applicator pad impregnated with a second composition comprising a second dermatological agent, are affixed to one surface of said support sheet.
- 8. The dispensing and applicator system according to claim 7, wherein the first dermatological agent is an effective anti-acne amount of a peroxide.
- 9. The dispensing and applicator system according to claim 8, wherein the first dermatological agent comprises benzoyl peroxide.
- 10. The dispensing and applicator system according to claim 8, wherein the first applicator pad is impregnated with a first composition comprising an effective anti-acne amount of an organic peroxide in combination with an aqueous gel comprising about 40-75% water, about 0.25-5% of an inorganic gelling agent, and about 2.5-10% of a mixture of an inorganic emollient oil and an emollient organic ester.
- 11. The dispensing and applicator system according to claim 10, wherein the first composition further comprises about 0.025-0.25% of an amphoteric surfactant.
- 12. The dispensing and applicator system according to claim 11, wherein the first composition further comprises about 10-20% of a (C.sub.2 -C.sub.4)alkanol.
- 13. The dispensing and applicator system according to claim 8, wherein the first applicator pad is impregnated with a first gelled composition comprising an effective anti-acne amount of an organic peroxide dispersed in about 50-80% water in combination with an effective amount of an inorganic gelling agent.
- 14. The dispensing and applicator system according to claim 8, wherein the first applicator paid is impregnated with a first gelled anhydrous composition comprising an effective anti-acne amount of an organic peroxide, about 75-90% of a mixture of inorganic and organic emollient oils, and about 1-10% of an inorganic gelling agent.
- 15. The dispensing and applicator system according to claim 14, wherein the composition further comprises about 0.1-1% of an amphoteric surfactant.
- 16. The dispensing and applicator system according to claim 8, wherein the second dermatological agent is an effective anti-acne amount of an antibiotic selected from the group consisting of erythromycin, tetracycline, clindamycin and the pharmaceutically acceptable salts thereof.
- 17. The dispensing and applicator system according to claim 16, wherein the the antibiotic is clindamycin or a pharmaceutically acceptable salt thereof.
- 18. The dispensing and applicator system according to claim 16, wherein the second composition comprises about 0.1-5% of the antibiotic dissolved or dispersed in mixture of water and a water-miscible organic solvent.
- 19. The dispensing and applicator system according to claim 18, wherein the second composition comprises an emulsion of about 0.1-5% clindamycin, erythromycin or a pharmaceutically acceptable salt thereof, about 80-95% aqueous alcohol and about 5-15% emollient organic esters.
- 20. The dispensing and applicator system according to claim 7, wherein the first dermatological agent is an effective keratolytic amount of salicylic acid.
- 21. The dispensing and applicator system according to claim 20, wherein the second dermatological agent is an effective anti-acne amount of an antibiotic.
- 22. The dispensing and applicator system according to claim 20, wherein the first composition comprises an aqueous-alcohol gel comprising about 0.5-10% salicylic acid.
- 23. The dispensing and applicator system according to claim 21, wherein the gel comprises about 0.5-5% of an organic gelling agent.
- 24. The dispensing and applicator system according to claim 7, wherein the first dermatological agent is an effective anti-acne amount of retinoic acid.
- 25. The dispensing and applicator system according to claim 24, wherein the first dermatological composition comprises about 0.01-0.25% retinoic acid.
- 26. The dispensing and applicator system according to claim 25, wherein the first dermatological composition further comprises a gelled mixture of water with a water-miscible organic solvent.
- 27. The dispensing and applicator system according to claim 24, wherein the first dermatological composition comprises about 0.01-0.25% retinoic acid, about 50-85% water, about 4-12% emollient oil, about 3-10% emollient wax stabilizer, about 5-20% polyhydric alcohol emollient and about 0.5-10% organic, water-soluble surfactant.
- 28. The dispensing and applicator system of claim 24, wherein the second dermatological composition comprises an effective amount of one or more sunscreen compounds.
- 29. The dispensing and applicator system of claim 24, wherein the second dermatological composition comprises about 50-85% water, about 4-12% emollient oil, about 3-10% emollient wax stabilizer, about 5-20% polyhydric alcohol emollient and about 0.5-10% organic, water-soluble surfactant.
- 30. The dispensing and applicator system of claim 7, wherein the first dermatological composition comprises an effective amount of one or more sunscreen compounds.
- 31. The dispensing and applicator system of claim 30, wherein the second dermatological composition comprises an effective amount of one or more sunscreen compounds.
- 32. The dispensing and applicator system of claim 7, wherein the first composition is a pigment-containing wax-based cosmetic composition and the second composition is a make-up remover composition comprising a wax-free mixture of about 25-75% water, about 15-70% of a water-insoluble liquid emollient oil and an amount of a surfactant effective to stabilize the mixture as a homogeneous emulsion.
- 33. The dispensing and applicator system of claim 32, wherein the first applicator pad is a hydrophilic polyurethane foam pad.
- 34. The dispensing and applicator system of claim 7, wherein the first dermatological agent is an effective dermatological amount of corticosteroid.
- 35. The dispensing and applicator system of claim 34, wherein the corticosteroid is dispersed throughout the first applicator pad as a powder.
- 36. The dispensing and applicator system of claim 34, wherein the first applicator pad is impregnated with a corticosteroid in combination with a pharmaceutically acceptable carrier.
- 37. The dispensing and applicator system of claim 7, wherein the second dermatological agent is an antihistamine, an antibiotic, an antifungal agent, a sunscreen, an emollient or a film-forming polymer.
Parent Case Info
This is a division, of application Ser. No. 07/986,597, filed Dec. 7, 1992, now U.S. Pat. No. 5,242,433.
US Referenced Citations (7)
Divisions (1)
|
Number |
Date |
Country |
Parent |
986597 |
Dec 1992 |
|