PATTERNS OF THYROID HORMONE DYNAMICS WITH AGING

Information

  • Research Project
  • 2051118
  • ApplicationId
    2051118
  • Core Project Number
    R15AG009840
  • Full Project Number
    1R15AG009840-01
  • Serial Number
    9840
  • FOA Number
  • Sub Project Id
  • Project Start Date
    5/1/1991 - 33 years ago
  • Project End Date
    2/28/1995 - 29 years ago
  • Program Officer Name
  • Budget Start Date
    5/1/1991 - 33 years ago
  • Budget End Date
    2/28/1995 - 29 years ago
  • Fiscal Year
    1991
  • Support Year
    1
  • Suffix
  • Award Notice Date
    4/25/1991 - 33 years ago

PATTERNS OF THYROID HORMONE DYNAMICS WITH AGING

DESCRIPTION (adapted from applicant's abstract): The proposed study will attempt to elucidate age-related changes in thyroid function by using a longitudinal study with cotton rats. Specifically, this study will simultaneously examine the time course of changes in thyroxine (T4) concentration, triiodothyronine (T3) concentration, thyroid stimulating hormone (TSH) concentration, T3 uptake, T4 turnover rate, and basal metabolic rates in cotton rats of age 20 days (post-weaning) and 6, 12, 18, 24, 27, and 30 months (approximate maximum lifespan). In addition, T3 turnover rates and liver and brown fat T4 deiodination rates will be measured for the same periods.

IC Name
NATIONAL INSTITUTE ON AGING
  • Activity
    R15
  • Administering IC
    AG
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    866
  • Ed Inst. Type
    SCHOOLS OF ARTS AND SCIENCES
  • Funding ICs
  • Funding Mechanism
  • Study Section
    BCE
  • Study Section Name
    Biochemical Endocrinology Study Section
  • Organization Name
    MISSOURI STATE UNIVERSITY
  • Organization Department
    BIOLOGY
  • Organization DUNS
    076255876
  • Organization City
    SPRINGFIELD
  • Organization State
    MO
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    65897
  • Organization District
    UNITED STATES