Claims
- 1. A method for the preparation of a compound of the formula ##STR10## wherein R is CH.sub.3 --(CH.sub.2).sub.6, CH.sub.3 --(CH.sub.2).sub.4 --CH.dbd.CH--(CH.sub.2).sub.2 or CH.sub.3 --(CH.sub.2).sub.8, which comprises culturing Polyangium brachysporum sp. nov. strain K481-B101 (ATCC 53080) in a nutrient medium containing an assimilable source of carbon and nitrogen under aerobic conditions, separating the mycelia produced and recovering the compound from the nutrient medium.
- 2. A method according to claim 1 wherein a fat or oil is added to the nutrient medium.
- 3. A method according to claim 1 wherein the separated mycelia are extracted with an organic solvent and the extract combined with the nutrient medium prior to recovery of the compound.
- 4. A method according to claim 1 wherein the compound is recovered from the nutrient medium by extraction with an organic solvent.
- 5. A method according to claim 1 wherein production of the compound is monitored using Candida albicans as the test organism.
- 6. A biologically pure culture of the microorganism Polyangium brachysporum sp. nov. strain K481-B101 (ATCC 53080).
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a division of our earlier co-pending application Ser. No. 855,649, filed Apr. 25, 1986, now U.S. Pat. No. 4,692,510, which is a continuation-in-part of application Ser. No. 771,090, filed Aug. 30, 1985, now abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4062943 |
Lindberg |
Dec 1977 |
|
4742047 |
Oka et al. |
May 1988 |
|
Divisions (1)
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Number |
Date |
Country |
Parent |
855649 |
Apr 1986 |
|
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
771090 |
Aug 1985 |
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