Patent Grant
9961757
This application claims the benefit of priority of European Patent Application No. 16169489.8, filed on May 13, 2016, European Patent Application No. 16169490.6, filed on May 13, 2016, European Patent Application No. 16169494.8, filed on May 13, 2016, and European Patent Application No. 16169497.1, filed on May 13, 2016, all of which are incorporated herein by reference.
The present disclosure relates to cyclotrons. It relates to isochronous sector-focused cyclotrons having enhanced control of the extraction path of energized charged particles being extracted from such cyclotron. In particular, embodiments of the present disclosure may allow for the extraction of an energized particle beam at various points of extraction and having the same optical properties.
A cyclotron is a type of circular particle accelerator in which negatively or positively charged particles are accelerated outwards from the centre of the cyclotron along a spiral path up to energies of several MeV. Unless otherwise indicated, the term “cyclotron” is used in the following to refer to isochronous cyclotrons. Cyclotrons are used in various fields, for example in nuclear physics, in medical treatment such as proton-therapy, or in radio-pharmacy. In particular, cyclotrons can be used for producing short-lived positron-emitting isotopes suitable for PET imaging (positron emitting tomography) or for producing gamma-emitting isotopes, for example, Tc99m, for SPECT imaging (single photon emission computed tomography).
A cyclotron generally comprises several elements including an injection system, a radiofrequency (RF) accelerating system for accelerating the charged particles, a magnetic system for guiding the accelerated particles along a precise path, an extraction system for collecting the thus accelerated particles, and a vacuum system for creating and maintaining a vacuum in the cyclotron.
A particle beam constituted of charged ions is introduced into a gap at or near the center of the cyclotron by the injection system with a relatively low initial velocity. As illustrated in
The magnetic system generates a magnetic field that guides and focuses the beam of charged particles along the spiral path until it is accelerated to its target energy. In the following, the terms “particles”, “charged particles”, and “ions” are used indifferently as synonyms. The magnetic field is generated in the gap defined between two magnet poles by two solenoid coils, 14, wound around these poles. Magnet poles of cyclotrons are often divided into alternating hill sectors and valley sectors distributed around a central axis. The gap between two magnet poles is smaller at the hill sectors and the larger at the valley sectors. A strong magnetic field is thus created in the hill gap portions within the hill sectors and a weaker magnetic field is created in the valley gap portions within the valley sectors. Such azimuthal magnetic field variations provide radial and vertical focusing of the particle beam every time the particle beam reaches a hill gap portion. For this reason, such cyclotrons are sometimes referred to as sector-focusing cyclotrons. In some embodiments, a hill sector has a geometry of a circular sector similar to a slice of cake with a first and second lateral surfaces extending substantially radially towards the central axis, a generally curved peripheral surface, a central surface adjacent to the central axis, and an upper surface defining one side of a hill gap portion. The upper surface is delimited by a first and second lateral edges, a peripheral edge, and a central edge.
It is common to have more than one point of extraction for extracting the particle beam from more than one point of a same hill sector of a cyclotron. An advantage of having at least a second extracting point within a same hill sector is to provide a fall-back extracting point in case the first extracting point is out of order and thus ensuring continuity of service. Another advantage is to lead the same ions with same energy towards two different targets at the same time, by positioning a first stripper so that it intercepts only a fraction of the particle beam, and the second stripper so that it intercepts part or all of the remaining fraction of the particle beam which passed next to the first stripper. One major issue, however, with at least two points of extraction is to ensure that the particle beam being extracted from a first point of extraction has the same properties (energy, focusing, etc.) as the one being extracted from a second point of extraction. To date, this issue has not been resolved satisfactorily yet.
There therefore remains a need in the art to provide an isochronous sector-focused cyclotron wherein the optical properties of an extracted particle beam do not depend on the position of a point of extraction located in a hill gap portion. This is particularly advantageous for cyclotrons having at least first and second points of extraction at a same hill sector, wherein the particle beam extracted from the first point of extraction has the same properties as the one extracted from the second point of extraction.
Embodiments of the present disclosure are defined in the appended independent claims. Further embodiments are defined in the dependent claims.
Embodiments of the present disclosure relate to a magnet pole for a cyclotron comprising at least 3 hill sectors and a same number of valley sectors alternatively distributed around a central axis, Z, each hill sector comprising an upper surface defined by:
In some embodiments, the centre of the arc of circle lies within the upper surface of the corresponding hill sector.
In certain aspects, to increase symmetry, the centre of the arc of circle may lie on the bisector of the upper surface, said bisector being defined as the straight line, joining the central axis to the midpoint.
The ratio, Rh/Lh, of the radius, Rh, of the arc of circle to the distance, Lh, from the central axis to the midpoint may be not more than 75%, for example, not more than 65%.
In certain aspects, to ease machining, the arc of circle may extend from the first upper distal end to the second upper distal end of the upper peripheral edge.
In some embodiments, each valley sectors of a magnet pole comprise a bottom surface, and each hill sector comprises:
In order to have smooth variations of the magnetic field, the peripheral surface may form a chamfer adjacent to the upper peripheral edge.
Embodiments of the present disclosure also relate to a cyclotron for accelerating a particle beam over a given path comprised within a gap, said cyclotron comprising first and second magnet poles as described above, wherein the first and second magnet poles are positioned forming said gap with their respective upper surfaces facing each other and symmetrically with respect to a median plane normal to the central axes of the first and second magnet poles, said central axes being coaxial, thus forming hill gap portions between two opposite hill sectors and valley gap portions defined between two opposite valley sectors.
In some embodiments, the cyclotron may comprise a first point of extraction, located in a hill gap portion between two opposite upper surfaces of hill sectors of the first and second magnet poles each having a peripheral edge comprising an arc of circle of radius Rh, wherein the given path of the particle beam is an outward spiral path cycling about the central axis until said first point of extraction PE1 whence the particle beam can be driven out of the cyclotron with a given energy, and wherein the arc of circle of said pair of upper peripheral edges is parallel to and reproduces a portion of the given path directly upstream of the first point of extraction, wherein upstream is defined with respect to the travelling direction of the particle beam.
The cyclotron may also further comprise a second point of extraction located downstream from the first point of extraction and within the hill gap portion adjacent to the upper peripheral edges of the same pair of opposed hill sectors, wherein the particle beam can be driven out of the cyclotron with said given energy at said second point of extraction, and wherein the arc of circle of said pair of upper peripheral edges is parallel to and reproduces a portion of the given path directly upstream of the second point of extraction.
In some embodiments, a particle beam follows a first extraction path downstream of the first point of extraction or, alternatively, follows a second extraction path downstream of the second point of extraction, wherein the length, L1, of the first extraction path within the hill gap portion may be equal to the length, L2, of the second extraction path within the same hill gap portion.
In some embodiments, the upper peripheral edge of the magnet poles of the cyclotron comprises a concave portion defining a recess extending at least partially over the peripheral surface of the corresponding hill sector.
In some embodiments, the upper surface of at least one hill sector of the magnet poles of the cyclotron further comprises:
These and further aspects of the present disclosure will be explained in greater detail by way of example and with reference to the accompanying drawings in which:
Geometry of a Cyclotron
The present disclosure relates to isochronous sector-focused cyclotrons, hereafter referred to as cyclotron of the type discussed in the technical background section supra. As illustrated in
As illustrated in
As illustrated in
The hill sectors 3 and valley sectors 4 of the first magnet pole 2 face the opposite hill sectors 3 and valley sectors 4, respectively, of the second magnet pole 2. The path 12 followed by the particle beam illustrated in
Average hill and valley gap heights are measured as the average of the gap heights over the whole upper surface and lower surface of a hill sector and a valley sector, respectively. The average of the valley gap height ignores any opening on the bottom surfaces.
The upper surface 3U is defined by (see
A hill sector 3 further comprises (see
The average height of a hill, Hh, sector is the average distance measured parallel to the central axis between lower and upper lateral edges.
An end of an edge is defined as one of the two extremities bounding a segment defining the edge. A proximal end is the end of an edge located closest from the central axis, Z. A distal end is the end of an edge located furthest from the central axis, Z. An end can be a corner point which is defined as a point where two or more lines meet. A corner point can also be defined as a point where the tangent of a curve changes sign or presents a discontinuity.
An edge is a line segment where two surfaces meet. An edge is bounded by two ends, as defined supra, and defines one side of each of the two meeting surfaces. For reasons of machining tools limitations, as well as for reduction of stress concentrations, two surfaces often meet with a given radius of curvature, R, which makes it difficult to define precisely the geometrical position of the edge intersecting both surfaces. In this case, the edge is defined as the geometric line intersecting the two surfaces extrapolated so as to intersect each other with and infinite curvature (1/R). An upper edge is an edge intersecting the upper surface 3U of a hill sector, and a lower edge is an edge intersecting the bottom surface 4B of a valley sector.
A peripheral edge is defined as the edge of a surface comprising the point located the furthest from the central axis, Z. If the furthest point is a corner point shared by two edges, the peripheral edge is also the edge of a surface which average distance to the central axis, Z, is the largest. For example, the upper peripheral edge is the edge of the upper surface comprising the point located the furthest to the central axis. If a hill sector is compared to a slice of tart, the peripheral edge would be the peripheral crust of the tart.
In an analogous manner, a central edge is defined as the edge of a surface comprising the point located the closest to the central axis, Z. For example, the upper central edge is the edge of the upper surface comprising the point located the closest to the central axis, Z.
A lateral edge is defined as the edge joining a central edge at a proximal end to a peripheral edge at a distal end. The proximal end of a lateral edge is therefore the end of said lateral edge intersecting a central edge, and the distal end of said lateral edge is the end of said lateral edge intersecting a peripheral edge.
Depending on the design of the cyclotron, the upper/lower central edge may have different geometries. The most common geometry is a concave line (or concave curve), often circular, of finite length (≠0), with respect to the central axis, which is bounded by a first and second upper/lower proximal ends, separated from one another. This configuration is useful as it clears space for the introduction into the gap of the particle beam and other elements. In a first alternative configuration, the first and second proximal central ends are merged into a single proximal central point, forming a summit of the upper surface 3U, which comprises three edges only, the central edge having a zero-length. If a hill sector is again compared to a slice of tart, the pointed tip of the slice would correspond to the central edge thus reduced to a single point. In a second alternative configuration, the transition from the first to the second lateral edges can be a curve convex with respect to the central axis, Z, leading to a smooth transition devoid of any corner point. In this configuration, the central edge is also reduced to a single point defined as the point wherein the tangent changes sign. Usually, even in the first and second alternative configurations, a hill sector does not extend all the way to the central axis, the central area directly surrounding the central axis is cleared to allow insertion of the particle beam or installation of other elements.
As shown is
A cyclotron according to an embodiment of the present disclosure may comprise N=3 to 8 hill sectors 3. For example, as illustrated in the Figures, N=4. For even values of N, the hill sectors 3 and valley sectors 4 must be distributed about the central axis with any symmetry of 2n, with n=1 to N/2. For example, according to a certain aspect, n=N/2, such that all the N hill sectors are identical to one another, and all the N valley sectors are identical to one another. For odd values of N, the hill sectors 3 and valley sectors 4 must be distributed about the central axis with a symmetry of N. For example, according to a certain aspect, the N hill sectors 3 are uniformly distributed around the central axis for all N=3−8 (i.e., with a symmetry of N). The first and second magnet poles 2 may be positioned with their respective upper surfaces 3U facing each other and symmetrically with respect to the median plane MP normal to the respective central axes Z of the first and second magnet poles 2, which are coaxial.
The shape of the hill sectors is often wedge shaped like a slice of tart (often, as discussed supra, with a missing tip) with the first and second lateral surfaces 3L converging from the peripheral surface towards the central axis Z (usually without reaching it). The hill azimuthal angle, αh, corresponds to the converging angle, measured at the level of the intersection point of the (extrapolated) upper lateral edges of the lateral surfaces at, or adjacent to, the central axis Z. The hill azimuthal angle, αh, may be between 360°/2N±10°, for example, between 360°/2N±5° or between 360°/2N±2°.
The valley azimuthal angle αv, measured at the level of the central axis Z may be between 360°/2N±10°, for example, between 360°/2N±5° or between 360°/2N±2°. The valley azimuthal angle αv may be equal to the hill azimuthal angle, αh. In case of a degree of symmetry of N, αv=360°/N−αh; for example, for N=4, αv is the complementary angle of αh, with αv=90°−αh.
The largest distance, Lh, between the central axis and a peripheral edge may be between 200 and 2000 mm, for example, between 400 and 1000 mm or between 500 and 800 mm. For a 18 MeV proton cyclotron, the longest distance, Lh, is usually less than 750 mm, and may be of the order of 500 to 750 mm, typically 520 to 550 mm. The upper peripheral edge has an azimuthal length, Ah, measured between the first and second upper peripheral ends, and can be approximated to, Ah=Lh×αh[rad].
The two magnet poles 2 and solenoid coils 14 wound around each magnet pole form an (electro-)magnet which generates a magnetic field in the gap 7 between the magnetic poles that guides and focuses the beam of charged particles (=particle beam) along a spiral path 12 illustrated in
When a particle beam is introduced into a cyclotron, it is accelerated by an electric field created between high voltage electrodes called dees (not shown), and ground voltage electrodes attached to the lateral edges of the poles, positioned in the valley sectors, where the magnetic field is weaker. Each time an accelerated particle penetrates into a hill gap portion 7h it has a higher speed than it had in the preceding hill sector. The high magnetic field present in a hill sector deviates the trajectory of the accelerated particle to follow an essentially circular path of radius larger than it followed in the preceding hill sector. Once a particle beam has been accelerated to its target energy, it is extracted from the cyclotron at a point called point of extraction PE, as shown in
Peripheral Hill Sector Design
According to an embodiment of the present disclosure, the upper peripheral edge of a hill sector comprises an arc of a circle 3ac whose centre is offset with respect to the central axis, and whose radius, Rh, is not more than 85% of a distance, Lh, from the central axis to a midpoint of the upper peripheral edge, which may be equidistant to the first and second upper distal ends (Rh/Lh≤85%).
In some embodiments, the ratio Rh/Lh of the radius, Rh, to the distance Lh, is not more than 70% (Rh/Lh≤75%), for example, not more than 65% (Rh/Lh≤65%). For example, for a value of Lh=500 mm, the radius, Rh, of the arc of the circle may be between 325 and 400 mm.
Because of the symmetry requirements of 2n for even values of N and a symmetry of N for odd values of N, discussed supra, the same symmetry must apply to the presence or not of an arc of a circle on the upper peripheral edges of the various hill sectors. Therefore, the upper peripheral edge of each hill sector, for example, comprises a same arc of a circle as defined supra.
Embodiments in which the upper peripheral edge comprises an arc of a circle whose centre is offset with respect to the central axis may homothetically approximate at least a portion of this upper peripheral edge to the highest energy (=last) orbit of the spiral path 12 in a hill gap portion 7h of the cyclotron. By “homothetically approximate the orbit” is meant that the arc of circle portion of the upper peripheral edge and the last orbit of particle adjacent to the point of extraction are both arcs of circle sharing the same centre with different radii. The arc of the circle may thus be approximately parallel to the portion of said last orbit directly adjacent to and upstream from the extraction point. The length of the path of the extracted orbit and the angle between the orbit and the upper peripheral edge may become independent of the azimuthal position of the extracting system (for example a stripper). In consequence, the characteristics of the extracted beam may be (nearly) independent of the position of the point of extraction within a hill gap portion 7h.
The highest energy orbit can be measured and/or computed with numerical simulations. The measured values and/or the results of the numerical simulation may be used to design and machine the upper peripheral edge so as to achieve the desired geometry of the hill sector.
As shown in
For example, as shown in
For wedge-shaped hill sectors, in order to increase symmetry, the centre of the arc of the circle may lie on the bisector of the upper surface, said bisector being defined as the straight line, joining the central axis to the midpoint of the upper peripheral edge.
In some embodiments, the arc of the circle extends from the first upper distal end to the second upper distal end of the upper peripheral edge, thus defining the whole peripheral edge of a hill sector. This geometry may be simpler to machine and may afford greater freedom to locate points of extraction at different locations within a hill gap portion 7h.
In some embodiments, the peripheral surface forms a chamfer adjacent to the upper peripheral edge.
As described supra and illustrated in
Usually, the highest energy orbit is located at a distance, dh, from the upper peripheral edge. This distance may be equal to approximately 0.6 times the average hill gap, Gh, measured in a hill gap portion, 7h. In this example, the radius, Rh, of the arc of the circle is therefore Rh=Rp+dh≈Rp+0.6 Gh, wherein Rp is the radius of the particle path within the hill gap portion upstream and adjacent to the point of extraction.
In certain aspects, a hill sector may comprise more than one point of extraction. For example, a hill sector may comprise two points of extraction. The second point of extraction, PE2, may be located directly downstream from the first point of extraction, PE1, in the same orbit as the first point of extraction and within the same hill gap portion. To increase symmetry, several or all the hill sectors of a cyclotron may comprise several points of extraction. For example, if the number, N, of hill sectors is equal to 4, then the number of points of extraction may be equal to 8.
As shown in
When the particle beam has reached its target energy, it may be extracted at a point of extraction and, it may then follow an extraction path downstream of the point of extraction. A part of this extraction path may lie between the first and second magnet poles and may thus be still comprised within the hill gap portion and subjected to the magnetic field. If the pair of opposite hill sectors comprises a first and a second points of extraction, the particle beam may be extracted either at the first or at the second point of extraction or at both. The particle beam may then follow either a first or a second extraction path downstream of the first or second point of extraction. With the circular geometry of at least a portion of the upper peripheral edge according to some embodiments of the present disclosure, the length, L1, of the extraction path within the gap downstream of the first point of extraction and the length, L2, of the extraction path within the gap downstream of the second point of extraction may be substantially equal. Having the same length of extraction paths downstream of the first and second points of extraction may ensure that the particle beam extracted from one point of extraction has similar optical properties as the one extracted from the second point of extraction.
The term “fitting” means that the pole insert has a general shape able to be precisely inserted into and nested in the recess.
In prior art cyclotrons comprising pole inserts, the pole inserts were often positioned in a recess machined off a lateral edge of the upper surface of the hill sectors. Access to such pole inserts is, however, rendered difficult by part of the RF accelerating system overlapping the upper lateral edge area. Access to such pole inserts requires removing the overlapping part of the RF system first. By positioning a pole insert on the upper surface, it can be accessed easily and directly for removal, machining and re-insertion into the recess. With the present embodiment, it may thus be easier and more efficient to reach the optimal pole insert topography yielding the predicted magnetic field and particle path.
In some embodiments, all pole inserts have the same shape and are made of the same material. In certain aspects, the pole insert is made of the same material as the corresponding hill sector.
In some embodiments, the recess extends along a longitudinal axis intersecting the central axis, and it is open ended at both ends and extends from the upper central edge all the way to the upper peripheral edge. In certain aspects, the longitudinal axis may intersect the upper peripheral edge at a point located at equal distance from the first and second upper distal ends, and wherein the first and second upper distal ends may be symmetrical with respect to the longitudinal axis. For example, except for the proximal portion 9p adjacent to the central edge, the pole insert may have a general parallelepiped shape, as illustrated in
In the embodiment of
The pole insert may be nested in the recess and may be reversibly fastened to the corresponding hill sector. For example, it may be coupled to the hill sector with screws.
As discussed supra, the pole insert may have a prismatic geometry along the longitudinal axis over at least 80% of its length, L9, excluding the converging proximal portion 9p, of length L9p. In embodiments in which the ridges between the hill upper surface 3U and the hill lateral surfaces are chamfered, the corresponding ridges of the proximal portion of the recess may be chamfered too.
The topography, illustrated in
The term “concave” means curving in or hollowed inward. The concave portion with respect to the central axis of an edge, is a portion of the edge curving towards the central axis. This term is opposed to the term “convex” that means curving out of or extending outward from the central axis.
In some embodiments, the upper peripheral edge 3up comprises a first and a second recess distal points 10rdp, defining the boundaries of a recess, and which are defined as the points where the tangent of the upper peripheral edge changes sign or presents a discontinuity. The first and second recess distal points may be separated from one another by a distance L10. The recess may also comprise a recess proximal point 10rpp defined as the point of the recess located closest to the central axis, Z. The first and second recess distal points 10rdp may join the recess proximal point 10rpp by a first and second recess converging edges 10rc. The recess depth, H10, is defined as the average height of the triangle formed by the first and second recess distal points 10rdp and the recess proximal point 10rpp, and passing by the recess proximal point 10rpp.
In some embodiments, the distance L10 between first and second recess distal points ranges between 5% and 50%, for example, between 10% and 30% or between 15% and 20% of the azimuthal length, Ah, of the upper peripheral edge.
The depth of the recess, 1110 may be between 3% and 30%, for example, between 5% and 20% or between 8% and 15% of the azimuthal length, Ah, of the upper peripheral edge.
In some embodiments, the recess also extends parallel to the central axis, Z, over the peripheral surface 3P from the upper peripheral edge 3up towards the lower peripheral line 3lp. The recess may thus extend over the peripheral surface over a fraction, of a height of the peripheral surface measured parallel to the central axis between the upper peripheral edge and lower peripheral line. The fraction, ζ, may be between 25% and 100%, for example, between 40% and 75% or between 45% and 55%.
In prior art cyclotrons, protruding gradient correctors were often used. Protruding gradient correctors have several drawbacks:
Using recessed gradient correctors instead of protruding gradient correctors may have several advantages. First, it may allow the reduction of the size of the vacuum chamber hosting the magnet poles leading to a decrease of energy required for evacuating the gases from the vacuum chamber and reducing the time of the gas evacuation. Second, the overall weight of the cyclotron may be decreased because, on the one hand, the weight of the hill sectors is slightly reduced instead of being increased and, on the other hand, the overall diameter of the inner surface of flux return yoke is decreased. Third, the position of the recesses may be precisely manufactured and positioned by numerically controlled machining allowing the optimization of the angle at which the particle beam crosses the peripheral edge of the hill sector. Fourth, when protruding gradient correctors deviate the magnetic field outwards, the magnetic field may be deviated inwards by recessed gradient correctors resulting in an inwards shift of the last cycles of the particles path, further away from the peripheral edge of the hill sector, where the magnetic field is more uniform than close to the peripheral edge. It may therefore be easier and more predictable to control the properties of the extracted particle beam, and particularly the focusing thereof. This deviation towards the acceleration area may also allow the power fed to the coils to be decreased.
In some embodiments, the recess is generally wedge-shaped with the first and second recess converging edges being straight (or slightly curved inwards or outwards) lines. The tip of the wedge corresponds to the recess proximal point and points in the general direction of the central axis. The converging angle, θ, at the tip of the wedge may be between 70° and 130°, for example, between 80° and 110° or 90°±5°. The expressions “inwards” and “outwards” used herein are to be understood as “towards” or “away from” the central axis, respectively.
The position of the recess may either be separated from the first and second lateral edges, or adjacent to the first or second lateral edge. In certain aspects, a hill sector comprises at least one recess separated from the lateral edges.
More generally, the converging portion of the wedge-shaped recess may have one of the following geometries:
In some embodiments, a point of extraction is located within a hill gap portion adjacent to the peripheral edges of a pair of opposed hill sectors. A recess may be located downstream from said first point of extraction wherein downstream is defined with respect to the direction of the particle beam. The recess may be precisely machined with respect to the point of extraction and to the extraction path such that the particle beam intersects a first converging recess edge with an angle of 90°±15° (cf.
As shown in
In conclusion, embodiments of the present disclosure may provide advantages, for example, allowing the length of the path of the extracted orbit and the angle between the orbit and the upper peripheral edge to be independent of the azimuthal position of the extracting system (for example, a stripper). Accordingly, the characteristics of the extracted beam may be (nearly) independent of the position of the point of extraction within a hill gap portion.
| Number | Date | Country | Kind |
|---|---|---|---|
| 16169489 | May 2016 | EP | regional |
| 16169490 | May 2016 | EP | regional |
| 16169494 | May 2016 | EP | regional |
| 16169497 | May 2016 | EP | regional |
| Number | Name | Date | Kind |
|---|---|---|---|
| 20060255285 | Jongen | Nov 2006 | A1 |
| 20140371076 | Jongen | Dec 2014 | A1 |
| 20170332473 | Abs | Nov 2017 | A1 |
| 20170332474 | Abs | Nov 2017 | A1 |
| Number | Date | Country |
|---|---|---|
| 1 069 809 | Jan 2001 | EP |
| 2 234 733 | Jan 1975 | FR |
| 1 485 329 | Sep 1977 | GB |
| H11 238599 | Aug 1999 | JP |
| Entry |
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| European Search Report dated Nov. 1, 2016, 5 pages. |
| Number | Date | Country | |
|---|---|---|---|
| 20170332475 A1 | Nov 2017 | US |
