The present disclosure pertains to a method and apparatus for measuring a temperature, and, in particular, measuring peripheral temperature in neonates.
It is well known to measure a temperature of a subject. Specifically, the core body temperature and the peripheral temperature are important measures for diagnostic purposes, including the evaluation of circulatory problems, perfusion, thermoregulation issues, heat/cold stress and infections.
Accordingly, it is an object of one or more embodiments of the present invention to provide a measuring system for contact-less, non-invasive determination of a temperature of a subject. The system comprises a body of engagement which may be configured to support a subject thereon; one or more sensors that generate one or more output signals conveying measurements related to a temperature of the subject, wherein one or more sensors are carried by the body of engagement; a thermal exchanger configured to exchange thermal energy with the body of engagement and/or the subject; and one or more processors configured to execute computer program modules, the computer program modules comprising a control module and a parameter determination module. The control module is configured to control the thermal exchanger to modulate a structural temperature of the body of engagement at or near a point of engagement between the subject and the body of engagement. The parameter determination module is configured to determine a peripheral temperature of the subject based on a thermal response of the subject to the modulation of the structural temperature based on the one or more output signals.
It is yet another aspect of one or more embodiments of the present invention to provide a method of contact-less, non-invasive determination of a temperature of a subject. The method comprises engaging a subject with a body of engagement; generating one or more output signals conveying measurements related to a temperature of the subject; modulating a structural temperature of the body of engagement at or near a point of engagement between the subject and the body of engagement; and determining a peripheral temperature of the subject based on a thermal response of the subject to the modulation of the structural temperature.
It is yet another aspect of one or more embodiments to provide a system configured for contact-less, non-invasive determination of a temperature of a subject. The system comprises means for engaging a subject with a body of engagement; means for generating one or more output signals conveying measurements related to a temperature of the subject; means for modulating a structural temperature of the body of engagement at or near a point of engagement with the subject; and means for determining a peripheral temperature of the subject based on a thermal response of the subject to the modulation of the structural temperature.
These and other objects, features, and characteristics of the present embodiments, as well as the methods of operation and functions of the related elements of structure and the combination of parts and economies of manufacture, will become more apparent upon consideration of the following description and the appended claims with reference to the accompanying drawings, all of which form a part of this specification, wherein like reference numerals designate corresponding parts in the various figures. It is to be expressly understood, however, that the drawings are for the purpose of illustration and description only and are not intended as a definition of any limits.
As used herein, the singular form of “a”, “an”, and “the” include plural references unless the context clearly dictates otherwise. As used herein, the statement that two or more parts or components are “coupled” shall mean that the parts are joined or operate together either directly or indirectly, i.e., through one or more intermediate parts or components, so long as a link occurs. As used herein, “directly coupled” means that two elements are directly in contact with each other. As used herein, “fixedly coupled” or “fixed” means that two components are coupled so as to move as one while maintaining a constant orientation relative to each other.
As used herein, the word “unitary” means a component is created as a single piece or unit. That is, a component that includes pieces that are created separately and then coupled together as a unit is not a “unitary” component or body. As employed herein, the statement that two or more parts or components “engage” one another shall mean that the parts exert a force against one another either directly or through one or more intermediate parts or components. As employed herein, the term “number” shall mean one or an integer greater than one (i.e., a plurality).
Directional phrases used herein, such as, for example and without limitation, top, bottom, left, right, upper, lower, front, back, and derivatives thereof, relate to the orientation of the elements shown in the drawings and are not limiting upon the claims unless expressly recited therein.
Measuring the core body temperature and/or the peripheral temperature of a subject may be important in many clinical situations, including but not limited to neonates in a neonatal intensive care unit (NICU). Adhesive temperature sensors may damage the skin and cause stress and/or pain when used. Additionally, it may upset a parent or other caretaker to see a baby covered with sensors and/or wires. Integrating sensor 17 within body of engagement 14, subject support structure 16, and/or incubator 15 may provide for contact-less, non-invasive determination of a temperature of subject 106. “Contact-less” refers to either refraining from the use of adhesives and/or refraining from direct skin contact in the context of this disclosure. Other implementations of body of engagement 14 that allow a sensor 17 to measure a temperature of subject 106 are contemplated. References to subject support structure 16 made herein are not intended to be limiting in scope. Rather, subject support structure 16 is referenced as an exemplary embodiment of body of engagement 14. Though sensor 17 is depicted and referred to as one sensor, the disclosure is not limited to one sensor. Sensor 17 may comprise one or more sensors, as well as multiple sensors of different types and capabilities.
Subject 106 may be placed inside incubator 15, e.g. on subject support structure 16, to enable temperature measurements. Sensor 17 may be used to measure the core body temperature of subject 106. Subject support structure 16 may thermally insulate subject 106 from the environment such that temperature measurements taken at or near a point of engagement between subject 106 and subject support structure 16 may (gradually) approximate the core body temperate of subject 106. The thermal principle at work here is known as the zero-heat flux principle, which may be described, e.g., in one or more related applications incorporated by reference into the present application. As a result, and for the same reason, contact-less, non-invasive determination of the peripheral temperature (and/or the difference between the core body temperature and the peripheral temperature) is problematic to obtain: the subject support structure provides thermal insulation to the skin; therefore the skin may not be cooled by the environment and the measured skin temperature may not be representative of what would normally be considered peripheral temperature. “Measure” refers to any combination of measuring, estimating, and/or approximating based on output generated by one or more sensors in the context of this disclosure.
Measurement sub-system 20 may include one or more of body of engagement 14 (e.g. subject support structure 16), sensor 17, thermal exchanger 11, and/or other components. Subject support structure 16 is configured to support subject 106 (not shown in
Thermal exchanger 11 is configured to exchange thermal energy with body of engagement 14 (e.g. subject support structure 16), e.g. by (locally) modulating a structural temperature, e.g. of subject support structure 16, at or near a point of engagement with subject 106 (not shown in
Returning to measuring system 10 of
Measuring system 10 may include user interface 120 configured to provide an interface between measuring system 10 and a user (e.g., user 108, a caregiver, a therapy decision-maker, etc.) through which the user can provide information to and receive information from measuring system 10. This enables data, results, and/or instructions and any other communicable items, collectively referred to as “information,” to be communicated between the user and measuring system 10. Examples of interface devices suitable for inclusion in user interface 120 include a keypad, buttons, switches, a keyboard, knobs, levers, a display screen, a touch screen, speakers, a microphone, an indicator light, an audible alarm, and a printer. Information is e.g. provided to subject 106 by user interface 120 in the form of auditory signals, visual signals, tactile signals, and/or other sensory signals.
By way of non-limiting example, in certain embodiments, user interface 120 includes a radiation source capable of emitting light. The radiation source includes one or more of an LED, a light bulb, a display screen, and/or other sources. User interface 120 may control the radiation source to emit light in a manner that conveys to subject 106 information related to, e.g., a breaching of a predetermined temperature threshold by subject 106.
It is to be understood that other communication techniques, either hard-wired or wireless, are also contemplated herein as user interface 120. For example, in one embodiment, user interface 120 is integrated with a removable storage interface provided by electronic storage 130. In this example, information is loaded into measuring system 10 from removable storage (e.g., a smart card, a flash drive, a removable disk, etc.) that enables the user(s) to customize the implementation of measuring system 10. Other exemplary input devices and techniques adapted for use with measuring system 10 as user interface 120 include, but are not limited to, an RS-232 port, RF link, an IR link, modem (telephone, cable, Ethernet, internet or other). In short, any technique for communicating information with measuring system 10 is contemplated as user interface 120.
Processor 110 is configured to provide information processing capabilities in measuring system 10. As such, processor 110 includes one or more of a digital processor, an analog processor, a digital circuit designed to process information, an analog circuit designed to process information, a state machine, and/or other mechanisms for electronically processing information. Although processor 110 is shown in
As is shown in
It should be appreciated that although modules 111, 112, 113, and 114 are illustrated in
Measurement module 114 is configured to control operation of measurement sub-system 20 in the provision of temperature measurements of subject 106. Measurement module 114 may direct operation of other modules of processor 110. Measurement sub-system 20 may operate without activating thermal exchanger 11. In this case, temperature measurements via sensor 17 may gradually approximate the core body temperature of subject 106 due to thermal insulation of sensor 17 by, e.g., subject support structure 16. Alternatively, and/or alternately, measuring sub-system 20 may operate whilst activating thermal exchanger 11 (e.g. through control module 111 as described below). In this case, a modulation of the structural temperature at or near the point of engagement between subject 106 and subject support structure 16 may provoke a (localized) thermal response by subject 106. Sensor 17 may be used to measure the thermal response of subject 106, e.g. the amount of thermal change, the rate of thermal change, and/or both.
By way of illustration,
Rp and Ri represent the thermal resistance of the body periphery (i.e. skin) of subject 106 and the (insulating) body of engagement 14 (e.g. subject support structure 16), respectively. A certain range of values for Rp may correspond with certain medical conditions, e.g. low perfusion of the body periphery. Additional insulation between skin 12 and sensor 17, e.g. bed sheets and/or clothing, may be represented in thermal model 30 as an additional thermal resistance in series to Rp, and accounted for accordingly. A dynamic thermal equation may incorporate thermal capacitances, i.e. for body periphery and/or the subject support structure.
Returning to measurement module 114 and measurement sub-system 20 of
By way of illustration
In some implementations, measurement sub-system 20 includes a thermal exchanger that comprise one or more of a cooling component, a heating component, and/or a component capable of both cooling and heating (e.g. a Peltier device).
Returning to
By way of illustration,
Returning to
Assessment module 113 may be configured to assess a diagnosis of conditions related to the temperature and/or temperature management of a subject, including, but not limited to, level of perfusion, vasoconstriction, cardiovascular issues, and/or hypothermia. Assessment may be based on information from parameter determination module 112, output signals from sensor 17, user input and/or other constituent components of measuring system 10.
In certain embodiments, method 600 may be implemented in one or more processing devices (e.g., a digital processor, an analog processor, a digital circuit designed to process information, an analog circuit designed to process information, a state machine, and/or other mechanisms for electronically processing information). The one or more processing devices may include one or more devices executing some or all of the operations of method 600 in response to instructions stored electronically on an electronic storage medium. The one or more processing devices may include one or more devices configured through hardware, firmware, and/or software to be specifically designed for execution of one or more of the operations of method 600.
At an operation 602, a subject is engaged with a body of engagement. In one embodiment, operation 602 is performed using a body of engagement similar to or substantially the same as subject support structure 16 (shown in
At an operation 604, output signals conveying measurements related to a temperature of a subject are generated. In one embodiment, operation 604 is performed using a sensor similar to or substantially the same as thermal sensor 17 (shown in
At an operation 606, a structural temperature of the body of engagement is modulated at or near the point of engagement with the subject. In one embodiment, operation 606 is performed using a thermal exchanger similar to or substantially the same as thermal exchanger 11 (shown in
At an operation 608, a peripheral temperature of the subject is determined based on a thermal response of the subject to the modulation of the structural temperature. In one embodiment, operation 608 is performed using a parameter determination module similar to or substantially the same as parameter determination module 112 (shown in
In the claims, any reference signs placed between parentheses shall not be construed as limiting the claim. The word “comprising” or “including” does not exclude the presence of elements or steps other than those listed in a claim. In a device claim enumerating several means, several of these means may be embodied by one and the same item of hardware. The word “a” or “an” preceding an element does not exclude the presence of a plurality of such elements. In any device claim enumerating several means, several of these means may be embodied by one and the same item of hardware. The mere fact that certain elements are recited in mutually different dependent claims does not indicate that these elements cannot be used in combination.
Although the embodiments have been described in detail for the purpose of illustration based on what is currently considered to be most practical and preferred, it is to be understood that such detail is solely for that purpose and not to pose any limits, but, on the contrary, is intended to cover modifications and equivalent arrangements that are within the spirit and scope of the appended claims. For example, it is to be understood that the present disclosure contemplates that, to the extent possible, one or more features of any embodiment can be combined with one or more features of any other embodiment.
This application is related to U.S. patent application Ser. No. 12/531,313, entitled “Methods and Devices for Measuring Core Body Temperature,” and filed Mar. 15, 2007, as well as U.S. Pat. No. 3,933,045, entitled “Temperature Measurement,” and filed Apr. 30, 1971. All of the related patents and applications are hereby incorporated by reference into the present application in their entirety.
Filing Document | Filing Date | Country | Kind | 371c Date |
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PCT/IB2012/053002 | 6/14/2012 | WO | 00 | 12/2/2013 |
Number | Date | Country | |
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61497301 | Jun 2011 | US |