Peristatic pump

Information

  • Patent Grant
  • 6494693
  • Patent Number
    6,494,693
  • Date Filed
    Monday, October 23, 2000
    24 years ago
  • Date Issued
    Tuesday, December 17, 2002
    21 years ago
Abstract
An improved peristaltic pump using a pumptube comprising a single tube of a relatively rigid and hard fluoroplastic material, preferably relatively rigid and hard polytetrafluoroethylene (PTFE), and a roller strap located between the pressure rollers of the peristaltic pump and the pumptube, is provided. The roller strap prevents direct contact between the pressure rollers of the peristaltic pump and the pumping section of the pumptube. The pumping section of the pumptube is formed or shaped into a flattened, oval-like shape which approximately conforms to the pumptube passageway in the peristaltic pump. The pressure rollers contact the roller strap and then compress the flattened side of the pumptube and, thereby, effecting transport or pumping of the fluid. The use of the strap prevents excessive tube expansion at the output back-pressure, thereby increasing the lifetime of the pumptube. Using the pumptubes and peristaltic pumps of this invention, corrosive, viscous, sensitive, biological, and/or high pressure fluids can be readily handled. The pumptube and peristaltic pumps of this invention are especially adapted to operate against high back- or counter-pressures.
Description




FIELD OF THE INVENTION




This invention generally relates to peristaltic pumps for transporting or pumping fluids. More specifically, this invention relates to an improved peristaltic pump using a pumptube comprising a single tube of a relatively rigid and hard fluoroplastic material, preferably relatively rigid and hard polytetrafluoroethylene (PTFE), and a roller strap located between the pressure rollers of the peristaltic pump and the pumptube. The pumping section of the pumptube, which is not directly contacted by the pressure rollers of the peristaltic pump, is pre-formed or shaped into a flaftened cross section with an overall U-shape which approximately conforms to the pumptube passageway in the peristaltic pump. The pressure rollers contact the roller strap and then compress the flattened side of the pumptube and, thereby, effect transport or pumping of the fluid. The use of the strap prevents excessive tube expansion at the output back-pressure, thereby increasing the lifetime of the pumptube. Using the pumptubes and peristaltic pumps of this invention, corrosive, viscous, sensitive, biological, and/or high pressure fluids can be readily handled. Moreover, fluids up to about 50° C. can be pumped at a back-pressure up to about 4 bar; higher operating temperatures may be possible with lower back-pressures. The pumptube and peristaltic pumps of this invention are especially adapted to operate against high back- or counter-pressures.




BACKGROUND OF THE INVENTION




Peristaltic pumps are preferred for certain applications where it is desirable to pump measured amounts of a fluid or to pump a fluid through tubing while avoiding contact between pump components and the fluid being pumped. In a typical peristaltic pump system, a length of tubing is contacted by a series of pressure rollers that rotate in a circular path. The pressure rollers contact and progressively compress a flexible pumptube at spaced intervals against a surface or raceway so as to flatten or locally reduce the cross-sectional area of the fluid passageway in the pumptube. Preferably, the cross-sectional area of the fluid passageway is effectively reduced to zero (i.e., complete occlusion) as each pressure roller moves over the pumping section of the pumptube. As the pressure rollers continue to roll over the pumptube, the successive flattened portions expand or return to the original cross-sectional area due to the resilience of the tube which generates a sub-atmospheric pressure in the fluid passageway to draw the fluid therein.




The efficiency and operating characteristics of a peristaltic pump generally depend on the physical and chemical characteristics of the pumptube. The pumptube generally must have a combination of properties including flexibility, resilience, durability, resistance to creasing, and resistance to adverse chemical or physical effects, since the pump may be used to pump diverse materials including acids, alkali, solvents, toxic, and sterile liquids.




Commercially available peristaltic pumptubes are generally uniformly cylindrical, flexible tubes with a uniform wall thickness which provide a fast recovery rate of the flattened portion to the normal cross-sectional area. Such pumptubes are normally formed from resilient elastomeric materials such as natural rubber, silicone, polychloroprene, and polyvinyl chloride. Such materials, however, have limited resistance to chemical degradation. Moreover, such materials may leach components (e.g., softening agents and the like) into the fluid being pumped and/or absorb components from the fluid being pumped. Thus, the use of pumps using such pumptubes is generally restricted to liquids having minimal degradation effects.




Fluoroplastic tubing, which has good corrosion resistance, generally has been found to lack resilience and tends to crease in use, thereby limiting the life of such tubing. U.S. Pat. No. 3,875,970 (Apr. 8, 1975) attempted to overcome this problem by providing a pumptube having a thin inner tubular portion of a corrosion resistant material (such as polytetrafluoroethylene) and a thicker outer tubular portion of a resilient elastomeric material (such as silicone, polychloroprene, flexible polyvinyl chloride, natural or synthetic rubber). The overall pumptube remained flexible. Although the design of this pumptube reportably extended the life of the tubing, it has not been as successful as desired and its use in commercially available peristaltic pumps appears to be very limited.




In addition, a variety of pumptubes incorporating various geometric configurations, including multiple layered tubes, have been used in peristaltic pumps. U.S. Pat. No. 3,105,447 (Oct. 1, 1963) used a double layered pumptube where both the inner and outer tubes consisted of rubber or an elastomer. The pumptube design allowed a lubricant to be pumped through the space formed between the inner and outer tubes. German Patent 3,322,843 A1 (published Jan. 3, 1985) also provided a double layered pumptube with a particularly soft and elastic inner layer and an impermeable outer layer. The inner layer could be formed of silicone, natural rubber, soft polyvinyl chloride, polyurethane, or fluoroelastomer; the outer layer could be formed of polyvinyl chloride, polyurethane, fluoroelastomer, and certain polyethylenes. The pumptube was flexible and maintained a circular cross-section in the uncompressed state. European Patent Publication 0,470,33 A1 (published Feb. 12, 1992) provided a flexible pumptube with an elastic reinforcing member or members disposed therein to reduce fatigue failure upon repeated compression and recovery of the tubing. U.S. Pat. No. 5,067,879 (Nov. 26, 1991) provided a flexible, single- or multi-layered pumptube having two longitudinally extending notches or groves in the outer surface. The groves were reported to improve the flexing characteristics of the tubing during compression and recovery. Although providing useful and significant advances in the art, each of these just described pumptubes has significant limitations for use in peristaltic pumps, especially for peristaltic pumps for corrosive and other difficult to handle liquids.




More recently, U.S. Pat. No. 5,482,447 provided a double layer pumptube having a inner tube and an outer tube, both of which were preferably polytetrafluoroethylene (PTFE). Although this pumptube was a significant advance over the prior art, the pumptube, largely because of its tube within a tube design, was more costly and difficult to manufacture than desired. Additionally, the pumptube's useful lifetime was not as high as desired when operated against a significant back-pressure.




The present invention provides an improved peristaltic pump and an improved pumptube. Using the peristaltic pump of this invention, a single shaped tube of rigid fluoroplastic material (preferably PTFE) can be used. Thus, many of the advantages obtained in the double layered PTFE pumptubes of U.S. Pat. No. 5,482,447 can be obtained using a significantly simplified pumptube (i.e., single tube construction) as provided herein. The pumptube and peristaltic pump of the present invention are especially adapted for use in systems which develop, or can develop, high back- or counter-pressures. Using the present system, peristaltic pumps can operate continuously to pump liquid against a counter-pressure of at least 4 bar at a flow rate of at least 4 liters per minute (LPM).




SUMMARY OF THE INVENTION




The present invention relates to an improved peristaltic pump using a pumptube comprising. a single tube of relatively rigid and hard fluoroplastic material, preferably relatively rigid and hard polytetrafluoroethylene (PTFE), and a roller strap located between the pressure rollers of the peristaltic pump and the pumptube. The roller strap is an inelastic material such as, for example, a polyester, an aromatic polyamide, or the like. Preferably, the roller strap is an aromatic polyamide because of its reduced tendency to form a “hammock” during operation. One especially preferred aromatic polyamide is KEVLAR™ (DuPont). A KEVLAR™ strap coated with polychloroprene on both flattened sides is even more preferred; one especially preferred strap is a 1 mm thick KEVELAR™ strap coated with 0.2 mm of polychloroprene on both flattened sides. The combination of the pumptube and the roller strap allows for improved performance, especially with regard to pumptube lifetime, when operating at relatively high back- or counter-pressure. The present pumptube and peristaltic pump can also be used when such back-pressures are not generated or are not likely to occur.




The pumping section of the pumptube is preformed or shaped into a flattened, oval-like shape (e.g., a flattened U-shape as shown in

FIG. 2

) which approximately conforms to the occlusion bed or pumptube passageway in the peristaltic pump. The pressure rollers contact the strap, rather than the pumptube itself, and thereby compress the flattened side of the pumptube and effect the transport or pumping of the fluid. The pressure rollers do not directly contact the pumptube since they are separated from the pressure rollers by the roller strap. The inner surface of the flattened fluid passageway is required to move only a relatively short distance when compressed by the pressure rollers. Moreover, the flatten portion of the pumptube is contained on its outer side by the pumptube passageway and on its inner side by the strap. The movement of the pumptube during compression is thus limited. Moreover, the strap prevents excessive expansion of the pumptube, especially in the roll-off section, when operated against a high back- or counter-pressure. Thus, the placement of the strap between the rollers and the pumping section of the pumptube prevents excessive expansion of the pumping section between the rollers themselves and between the last roller and the outlet end, especially when exposed to a significant back or counter pressure. Preferably, the strap rests on guide cams on both the roll-on and roll-off portions of the pump to further limit expansion of the pumptube in the roll-on and/or roll-off portions. Thus, the materials forming the pumptube remain within their elastic fatigue limits, even when operated against high back-or counter-pressure, thereby significantly reducing fatigue failure and significantly increasing the lifetime of the pumptube. The pumptube systems and peristaltic pumps of this invention are especially adapted for situations where the back- or counter-pressure may vary over time. The pumptube systems and peristaltic pumps of this invention can be used for pumping and transporting corrosive, viscous, sensitive, biological, and/or high pressure fluids at high flowrates and against significant back- or counter-pressure.




The present invention provides a peristaltic pump for transporting fluids, said peristaltic pump comprising




(a) a pump housing containing a pumptube passageway;




(b) a pumptube to fit within the pumptube passageway, the pumptube having inlet and outlet ends extending outside the pump housing, a pumping section contained within the pumptube passageway, and a fluid passageway extending through the pumptube from the inlet end to the outlet end;




(c) a plurality of pressure rollers rotatably mounted within the housing, whereby each roller in turn compresses the pumping section of the pumptube contained within the pumptube passageway so as to transport fluid from the inlet end to the outlet end of the pumptube;




(d) a guide cam attached to the pump housing to support the pumping section of the pumptube adjacent to the outlet end; and




(e) a strap mounted between the plurality of pressure rollers and the pumping section of the pumptube and between the guide cams and the ends of the pumping section of the pumptube so that the pressure rollers are able to compress the pumping section without directly contacting the pumping section;




wherein at least the pumping section of the pumptube comprises a single rigid fluoroplastic tubing preformed to fit within the pumptube passageway such that the pumptube within the pumping section is flattened into an oval-like shape with an oval-shaped fluid passageway such that the pressure rollers compress the pumping section of the pumptube essentially along the flattened side of the oval-like shape without contacting the pumping section. Preferably, the pump housing also has a guide cam to support the pumping section of the pumptube adjacent to the inlet end.




The present invention also provides a peristaltic pump for transporting fluids, said peristaltic pump comprising




(a) a pump housing containing a pumptube passageway;




(b) a pumptube having inlet and outlet ends extending outside the pump housing, a pumping section contained within the pumptube passageway, and a fluid passageway extending through the pumptube from the inlet end to the outlet end;




(c) a plurality of pressure rollers rotatably mounted within the housing, whereby each roller in turn compresses the pumping section of the pumptube contained within the pumptube passageway so as to transport fluid from the inlet end to the outlet end of the pumptube; and




(d) a strap mounted between the plurality of pressure rollers and the pumping section of the pumptube so that the pressure rollers are able to compress the pumping section without contacting the pumping section;




wherein at least the pumping section of the pumptube comprises a single rigid fluoroplastic tubing preformed to fit within the pumptube passageway such that the pumptube within the pumping section is flattened into an oval-like shape with an oval-shaped fluid passageway such that the pressure rollers compress the pumping section of the pumptube essentially along the flattened side of the oval-like shape without contacting the pumping section. Preferably, guide cams are attached to the pump housing to provide support to the strap near and/or at end of the roll-on and roll-off sections of the peristaltic pump.




The present invention also provides a pumptube system comprising a pumptube and a roller strap, which system is suitable for use in a peristaltic pump having a pumptube passageway and a plurality of pressure rollers for compressing the pumptube whereby a fluid can be transferred, wherein the pumptube comprises




(a) inlet and outlet ends;




(b) a pumping section located between the inlet and outlet ends; and




(c) a fluid passageway extending through the pumptube from the inlet end to the outlet end;




wherein at least the pumping section of the pumptube comprises a single rigid fluoroplastic tubing, wherein the pumptube is preformed to fit within the pumptube passageway such that the pumptube within the pumping section is flattened into an oval-like shape with an oval-like fluid passageway such that the pressure rollers compress the pumping section of the pumptube essentially along the flattened side of the oval-like shape;




and wherein the roller strap comprises an inelastic material located between the pressure rollers and the pumping section of the pumptube so that the pressure rollers do not contact the pumping section of the pumptube when the pumping section is compressed.




The present invention also provides a method of preparing a pumptube suitable for use in a peristaltic pump having a pumptube passageway, wherein the pumptube has a flattened, oval-like shaped pumping section with an oval-like fluid passageway, a plurality of pressure rollers, an inelastic strap located between the pressure rollers and the pumptube, wherein the pressure rollers, through pressure transferred though the strap, compress the pumptube via the strap without directly contacting the pumptube, whereby a fluid can be transferred, said method comprising




(a) forming a length of a rigid fluoroplastic tubing having a fluid passageway extending throughout the length of the rigid fluoroplastic tubing;




(b) placing a central portion of the length of rigid fluoroplastic tubing in a clamping fixture capable of compressing the central portion;




(c) compressing the central portion of the rigid fluoroplastic tubing at or near room temperature using the clamping fixture to form a fully compressed and flattened section in the central portion;




(d) allowing the fully compressed and flattened section to expand to form the flattened, oval-like shaped pumping section with the oval-like fluid passageway therein;




(e) heating at least the pumping section of the rigid fluoroplastic tubing to a temperature sufficient to increase the malleability of the rigid fluoroplastic tubing;




(f) placing the heated rigid fluoroplastic tubing in a molding fixture capable of molding the pumptube into a shape to fit within the pumptube passageway;




(g) molding the pumptube into the shape to fit within the pumptube passageway without obstructing the oval-like fluid passageway; and




(h) allowing the pumptube to cool to or near ambient temperature within the molding fixture;




whereby the pumptube fitting within the pumptube passageway of the peristaltic pump is obtained. Preferably a core is placed within the fluid passageway during the molding step to help maintain the desired cross-section within the oval-like fluid passageway and to prevent obstructing the oval-like fluid passageway. Alternatively, gas under pressure can be pumped through the fluid passageway during the molding step to achieve the same effect. Of course, such a core would be placed within the fluid passageway before step (e) and then removed after step (h).




These and other embodiments and advantages of the present invention will be apparent from a consideration of the present specification and drawing.











DESCRIPTION OF FIGURES





FIG. 1A

is a schematic view of a peristaltic pump with a pumptube


10


as provided by the present invention.

FIG. 1B

provides a side view of the peristaltic pump of

FIG. 1A

along section line BB. For clarity, the roller strap


20


in

FIGS. 1A and 1B

are shown in a light gray color.

FIG. 1C

provides a modified guide cam having a leaf spring. For clarity, the roller strap


20


in

FIG. 1C

illustrated as discontinuous grayscale line.





FIG. 2A

illustrates a formed pumptube of the present invention suitable for use in the peristaltic pumps of

FIGS. 1 and 4

.

FIGS. 2B and 2C

provide cross-sectional views of the pumping section through line BB during the non-compressed state (


2


B) and the compressed state (


2


C).

FIG. 2D

provide a cross-sectional view through line DD.





FIG. 3A

illustrates a roller strap (in perspective view) used to cover the pressure rollers in the peristaltic pump of FIG.


1


.

FIG. 3B

illustrates a “slim-waisted” roller strap (in side view) which can be used to prevent or reduce the likelihood of “strap-hammock” formation during operation of the peristaltic pump.

FIG. 3C

illustrates the relationship of the “slim-waisted” strap, the flattened portion of a pumptube, and a roller during operation.

FIG. 3D

illustrates a roller strap (in side view) having a “hole” or slot to provide a controlled backleak from the outlet to the pumping section during operation of the peristaltic pump; the amount of backleak will be proportional to the back-pressure, the number of holes, and the hole sizes.





FIG. 4

is a schematic view of another embodiment of the peristaltic pump of this invention using a continuous roller strap. The modified guide cams having leaf spring biasing elements of

FIG. 1C

are also shown. For clarity, the roller strap


20


is illustrated using a light gray color and the pumptube is omitted.





FIG. 5A

illustrates a fixture for pre-forming the flattened pumping section of the pumptube.

FIG. 5B

provides a side view of the pumptube and fixture along section line BB.





FIG. 6A

illustrates a fixture for forming the pumptube of

FIG. 2

in a U-shaped to fit the pumptube passageway of FIGS.


1


and/or


4


.

FIG. 6B

provides a side view of the pumptube and fixture along section line CC.











DETAILED DESCRIPTION OF THE INVENTION




This invention relates to improved peristaltic pumps and to improved pumptube systems for use therein. The improved pumptube system consists of a single rigid fluoroplastic tube and a corresponding roller strap. The pumping section of the pumptube is formed or shaped into a flattened, oval-shaped form with an oval-shaped fluid passageway. The pumping section, although compressed by the pressure rollers during operation of the peristaltic pump, is not in contact with the pressure rollers. The roller strap is placed between the pressure rollers and the pumping section. Pumping pressure is applied to the roller strap by the pressure rollers and is then transmitted to the pumping section of the pumptube. The indirect transmission of pressure compresses the pumptube and pumps the liquid. The use of the roller strap allows the length of pumping section of the pumptube to be essentially, and closely, confined or contained within a pumptube cavity defined by the pumptube passageway (i.e., the occlusion bed) and the roller strap. By confining the pumping section within the pumptube cavity, the overall movement of the pumptube during compression and decompression is significantly limited. More specifically, the exit portion or roll-off section of the pumping section cannot significantly expand when exposed to back- or counter-pressure downstream from the pump. Thus, the present pumptube is especially useful in conditions where a significant back-or counter-pressure is encountered or may develop (e.g., a variable restriction downstream such as a filter which can become partially clogged).




A pumptube


10


is shown in combination with one embodiment of an assembled peristaltic pump


30


and a roller strap


20


in FIG.


1


A. The pumptube


10


is separately shown in

FIG. 2A

; the roller strap is separately shown in FIG.


3


A. The formed pumptube


10


is a single, rigid fluoroplastic tube having an inlet portion


12


A, an outlet portion


12


B, and a flattened pumping section


14


. The flattened pumping section


14


has flattened fluid passageway


16


. The inlet portion end


12


A is attached to a fluid container or source by an appropriate connector (not shown) and the outlet end


12


B is attached to a fluid container or receiver by an appropriate connector (also not shown) so as to move fluid from the fluid source to the fluid receiver via pumptube


10


. The “restriction” at point


12


C on the outlet side


12


B of the pumptube represents a possible source of back-pressure.




As one of ordinary skill in the art will understand, the outlet and inlet ends in pumptube


10


are essentially of the same configuration and cross-sectional area (see FIG.


2


); they can, if desired, be of different configurations and/or cross-sectional areas. The pumping section


14


of pumptube


10


is flattened and shaped to conform to the pumptube passageway of the particular peristaltic pump used (one such pumphead is shown in FIG.


1


). The pumptube


10


in

FIGS. 1 and 2

and its flattened pump section


14


essentially forms a portion of a circular section (i.e., U-shaped; see

FIG. 2

) to fit and conform to the pumptube passageway (formed by the occlusion bed


38


and roller strap


20


) of the peristaltic pump in FIG.


1


. Other shapes can be used so long as they conform to the pumptube passageway of the pump and have flattened and oval-like shaped pumping sections


14


as described herein. Generally abrupt changes in direction (i.e., sharp or tight bends and the like) should be avoided in the pumptubes of this invention. Such sharp bends could significantly reduce or restrict the cross-sectional area of the fluid passageway (perhaps even closing it completely), thereby adversely affecting the operational characteristics of the pumptube and peristaltic pump.




As shown in

FIG. 1

, the assembled peristaltic pump


30


is formed of the following major components: housing


34


(including guide bars


35


, adjustment assembly


40


, and thumb screw


42


), a slidable member


32


, roller assembly


41


, and strap assembly


50


(including roller strap


20


, guide cams


46


and


48


, and spring assembly


52


). The circular portion


38


of slidable member


32


forms the occlusion bed to receive the flattened section


14


of pumptube


10


. The flattened portion


14


of pumptube


10


fits within the pumptube passageway formed by occlusion bed


38


and roller strap


20


; generally the flattened portion


14


of the pumptube


10


extends from the leading edge


46


A of guide cam


46


, through the occlusion bed


38


, to the trailing edge


48


A of guide cam


48


(see FIG.


1


A). The roller assembly


41


consists of a plurality of rollers


36


and pump drive shaft


44


. As shown in

FIG. 1A

, the drive shaft


44


allows rotation of the roller assembly in a counter clockwise direction (as indicated by the arrow on the assembly). If desired, the pump could be made reversible whereby the rotation could be in the opposite direction. Riding the strap


20


over the guide cams


46


and


48


, regardless of the flow direction, would allow the pumptube to operate at high back-pressures while still preventing excessive tube expansion at the output end.




The roller assembly


41


is locked or held in place on drive shaft


44


using locking key


44


A or other suitable locking devices. Strap


20


is placed between the rollers


36


and the pumptube


10


. Thus, the spinning rollers


36


never physically or directly contact the pumptube


10


. The pumptube


10


is compressed by pressure transmitted through the roller strap


20


from the pressure rollers. The roller assembly


41


shown in

FIG. 1A

has six pressure rollers


20


. Although fewer pressure rollers can be used, it is generally preferred that five or more pressure rollers be used in order to reduce the distance between any two adjacent rollers and, thus, the distance in which the roller strap


20


is unsupported. More preferably, the roller assembly


41


has five to eight pressure rollers with five or six pressure rollers being most preferred.




The strap biasing assembly


50


consists of the roller strap


20


, the two guide cams


46


and


48


, and spring or biasing element


52


. As shown in

FIG. 1B

, the width of the roller strap


20


is preferably about the same width as the pressure rollers


36


. The roller strap


20


has a fixed end


20


A and a floating end


20


B. As shown in

FIG. 1A

, the fixed end


20


A is attached to guide cam


46


. From its fixed position on guide cam


46


, the roller strap


20


loops around the outer surface of guide cam


46


, the outer surfaces of the pressure rollers


36


, and the outer surface of guide cam


48


. The floating end


20


B is then attached to fixed end


20


A (or to a portion of housing


32


or guide cam


46


) via biasing element


52


. Preferably, the biasing element


52


is a spring. The biasing element


52


should be sufficient to maintain the roller strap


20


tightly against the outer surface of the pressure rollers


36


and guide cams


46


and


48


during operation. Preferably the biasing element


52


is adjustable so that the pressure on the roller strap


20


can be adjusted. Generally, the strap is stretched by a pulling force equivalent to about


25


to about


30


kg.




The strap for use in the peristaltic pump of

FIG. 1

is shown separately in FIG.


3


A. At or near both ends (


20


A and


20


B) of the strap


20


are mounting holes


21


for attaching to the guide cam


46


(adjacent to the inlet portion


12


A of the pumptube


10


) and to the biasing assembly


50


(adjacent to the outlet portion


12


B). Other means of attachment can, of course, be used, including, for example, plastic or metal brackets or connecters attached to the ends of the strap, brackets or connectors formed of the same material as the strap and, if desired, integral with the strap. As those skilled in the art will realize, the fixed end


20


A should preferably be located adjacent to the inlet


12


A and the floating end


20


B should be located adjacent to the outlet


12


B of the pumptube since rotation of the roller assembly


41


will push or pull the strap in the counter-clockwise same direction (see FIG.


1


).




A “slim-waisted” roller strap


20


, which can be used to reduce “hammock” formation, is shown in FIG.


3


B. The portion


20


C is reduced in size relative to ends


20


A and


20


B. As shown in

FIG. 3C

, this narrowed portion


20


C (shown between the roller


36


and the fattened portion


14


of the pumptube) will have a reduced tendency to distort or form a hammock during operation since the strap


20


C is fully contacted with both the roller


36


and the pumptube portion


14


across essentially its entire width during operation. Of course, a similar effect could be obtained by simply making the width of the entire strap (i.e., from one end to the other) of a suitable size.




The two guide cams


46


and


48


are situated in the housing


34


so that the portions and length of the roller strap


20


which are unsupported at the roll-on and roll-off positions can be minimized or even eliminated. By fully supporting the roller strap


20


, excessive pumptube expansion at output back-pressure is significantly reduced or eliminated, thereby significantly increasing pumptube lifetimes. If desired, the two guide cams


46


and


48


can be adjustable within the housing


34


. Thus, the leading edge


46


A of guide cam


46


could be finely adjusted to minimize the distance from the leading edge


46


A to the first contact point of the roller strap


20


with the first pressure roller (point


20


C in FIG.


1


A). Likewise, the trailing edge


48


A of guide cam


48


could be adjusted to minimize the distance from the trailing edge


48


A to the last contact point of the roller strap


20


with the pressure roller


36


A (point


20


D in FIG.


1


A).




In operation, the pumptube


10


is placed in the peristaltic pump


30


in

FIG. 1

by opening the adjustment assembly


40


and moving slidable member


32


back towards the adjustment assembly


40


. This allows the pumptube


10


to be inserted into the peristaltic pump. Once the pumptube


10


is in place (between the roller strap


20


and the occlusion bed


38


as illustrated in FIG.


1


A), the slidable member


32


is moved back into the position shown in FIG.


1


and held securely in place using adjustment assembly


40


. When properly adjusted, the flattened portion


14


is fitted snugly within the pumptube passageway formed by the roller strap


20


and occlusion bed


38


. Thumb screw


42


can be tightened against the pumptube to prevent excessive creeping or movement of the pumptube during operation (i.e., prevent or reduce the tendency of the pumptube to migrate counter-clockwise during operation).




The drive shaft


44


is used to rotate the roller assembly


41


as shown in FIG.


1


. As the roller assembly


41


rotates, the individual rollers


36


compress the flattened portion


14


of the pumptube


10


by exerting pressure through the roller strap


20


. The notations in

FIG. 1

for pressure rollers


36


A and


36


B are intended to refer to the general location of any of the pressure rollers


36


as they pass through the locations indicated by


36


A and


36


B in FIG.


1


. As roller


36


A passes out of contact with strap


20


(and indirectly the flattened portion


14


), the portion of the fluid passageway


16


between rollers


36


A and


36


B (i.e., the roll-off section) will be at the pressure P


o


of the outlet end


12


B of the pumptube


10


. The remainder of the fluid passageway


16


(i.e., from location of roller


36


B back to the inlet end


12


A will be at the inlet pressure P


i


(normally around 1 atmosphere). That is, the pressure within the pumptube from roll-on up through roller


36


B, assuming no back leakage from the section between rollers


36


A and


361


, will generally remain at, or close, to P


i


. Thus, in normal operation, the fluid passageway


16


between positions


36


A and


36


B will be subjected to repeated cycling between P


i


and P


o


. If not contained within, and restrained by strap


20


, the pumptube in this area would tend to continuously flex and expand. Under such conditions, pumptubes constructed of relatively rigid fluoropolymers would have a very short lifetime (on the order of minutes) due to stress failure from the continuous exposure to the pressure differential. Using strap


20


of this invention prevents excessive flexing or expanding of the fluid passageway


16


as it is continuously exposed to the pressure differential. By preventing or substantially reducing movement (i.e., expansion due to pressure P


o


and then returning to the original cross section at P


i


) of the pumptube in the region between rollers


36


A and


36


B, the lifetime of the pumptube can be significantly increased. Thus, for example, pumptubes of this invention have been used in excess of about 20 hours when operated at a back-pressure (P


o


) of about 4 bar and a pumping rate of about 4 liters per minute. Similar pumptubes used in conventional peristaltic pumps (i.e., without the roller strap


20


and biasing assembly


50


) operated under these same conditions would be expected to fail within a matter of minutes (generally within 60 minutes or less). Indeed, such pumptubes in a conventional peristaltic pump would have an essentially zero useful lifetime.




As those skilled in the art will realize, high pressure peaks (e.g., about 6 to about 8 bar) may occur at the output end of the fluid passageway. If these high pressure peaks are sufficiently high, pumptube lifetime may be reduced. Such high pressure peaks can be reduced or attenuated by providing controlled backleaks at the output end of the fluid passageway. One method would be to tighten the occlusion screw


40


to just completely close or occlude the pumptube passageway


14


under operating conditions (e.g., 4 bar and 4 liters/minute). Higher backpressures (i.e., greater than the pressure under which the adjustment was made) would automatically open a minor backleak or “hole” past the roller exposed to the higher backpressure, thereby reducing excess pressure. Once the backpressure is reduced to the adjusted value, this “hole” would automatically close. Another method to achieve such controlled backleaks is to increase the outer radius of the occlusion bed near the output end so that the last roller


36


A does not fully compress or occlude the pumping section


14


near the output end. Alternatively, such controlled backleaks can be obtained by providing one or more suitably placed holes in the strap at or just before roller roll off at the output end. Such holes prevent the roller/strap combination from completely occluding the fluid passageway at that point, thereby providing the controlled backleak.

FIG. 3D

illustrates a strap with one such hole


20


D. Although other shaped holes can be used, an elongated hole or slot


20


D would generally be preferred since it is easier to place such a slot over the roller roll off at the output end.




Another embodiment of the peristaltic pump of this invention using a continuous, preferably seamless, loop as the roller strap


20


is shown in FIG.


4


. (Similar elements in

FIGS. 1 and 4

are similarly numbered and act in similar ways. Thus, only the features directed to the continuous loop in

FIG. 4

need be discussed. The pumptube has been omitted from

FIG. 4.

) The roller strap


20


in the peristaltic pump of

FIG. 4

is a continuous loop which encircles guide cams


46


and


48


as well as the individual rollers


36


within the roller assembly


41


. The biasing assembly


50


of this embodiment comprises a take-up mechanism


23


having a slot


25


for receiving a folded-over portion or end


27


of the continuous roller strap


20


. Once the folded portion


27


is engaged in the slot


25


, the take-up mechanism


23


can be rotated in the direction shown in

FIG. 4

to tighten the roller strap


20


. Once the roller strap


20


is properly tightened (e.g., a force equivalent to about 25 to about 30 kg), the take-up mechanism


23


can be locked in place using, for example, a locking screw or bolt, a ratchet system, or other conventional systems. Although it is preferred that roller strap


20


in

FIG. 4

is a continuous loop, a non-continuous roller strap could also be used by simply inserting both ends of such a roller strap in slot


25


and then tightening the take-up mechanism


23


as described above. Using a continuous loop, especially a continuous and seamless loop, generally allows for a longer lifetime for the roller strap since the strap can be moved so as to allow a new length of the roller strap to contact the pressure rollers. Using this embodiment, of course, the continuous roller strap


20


does not require mounting holes


21


as shown in FIG.


3


.





FIG. 1C

illustrates a modified guide cam


48


having a leaf spring


47


mounted on the guide cam via spring screw


49


. In operation, the roller strap would ride upon the leaf spring


47


which would provide a biasing action against the roller strap and help hold it tightly to the rollers. The strength of the leaf spring


47


can be adjusted as needed to maintain proper tension on the roller strap.

FIG. 4

illustrates the use of such leaf springs


47


on both guide cams


46


and


48


.





FIG. 2

illustrate a pumptube


10


suitable for use in the peristaltic pumps of

FIGS. 1 and 4

.

FIGS. 2B

(uncompressed state) and


2


C (compressed state) show a cross-section view of the pumping section


14


through line B—B in

FIG. 2A

;

FIG. 2D

shows a cross-section view of the inlet


12


A through line DD. As shown in

FIG. 2B

, the uncompressed state of the fluid passageway


16


is flattened and has an oval-like shape. By “oval-shaped” in regard to the pumping section


14


and the fluid passageway


16


, it is meant that the shape is generally oval with a relatively smaller or minor diameter parallel to the flattened side (i.e., x-axis) and a relatively larger or major diameter parallel to the y-axis as shown in FIG.


2


. The oval-shaped fluid passageway may be in the form of an oval, an ellipse, a football shape, an elongated slit or slot having torpedo-shaped ends, and the like so long as the minor diameter is significantly less than the major diameter. In fact, a football shape or elongated slit having torpedo-shaped ends (as suggested in

FIG. 2B

) may be preferred because such the narrow ends of the fled passageway


16


should be exposed to less stress when compressed. It is generally preferred that the major diameter of the fluid passageway is at least 3 times, and more preferably at least


5


times, greater than the minor diameter. In operation, pressure rollers will contact the flattened surface and compress the pumping section as shown in

FIG. 2B

to form the compressed configuration shown in FIG.


2


C. As can be seen in

FIG. 2C

, the fluid passageway


16


has been effectively occluded (i.e., closed) as represented by the straight line


16


. Although complete occlusion (as shown in

FIG. 2C

) is generally preferred, occlusions less than 100 percent can also be employed. Once the pressure roller passes by a given point on pumping section


14


, that point of the pumptube returns to the uncompressed state shown in FIG.


2


B. The maximum distance the surfaces of the fluid passageway


16


must travel for complete occlusion is the minor diameter. By reducing the distance over which the tube material must travel for occlusion, materials of construction having lower elastic fatigue limits can be employed.




The movement associated with repeated occlusion and recovery (i.e., moving from

FIG. 2B

to


2


C to


2


B repeatedly) is well within the elastic fatigue range of rigid and hard fluoroplastic materials, including polytetrafluoroethylene, used in the present pumptubes.




As noted above, the pumptubes of the present invention, in combination with the roller strap


20


, limit the movement in the pumping section


14


during occlusion and recovery so as to maintain the materials of construction (i.e., fluoroplastic tubing) within their elastic fatigue limits.




Moreover, the roller strap


20


limits excessive and damaging expansion of the fluid passageway


16


when exposed to pressures higher than atmospheric. This is especially critical in the roll-off portion of the pumptube (i.e., the distal end of the flattened portion of the pumptube which includes the length between pressure rollers


36


A and


36


B and the length from pressure roller


36


A to the end of the flattened portion). The roller strap


20


prevents the distal end of the flattened portion of the pumptube from expanding during the periodic removal of compression that results from the passage of the terminal roller pressure (i.e., during the roll-off phase). The failure associated with fatigue (i.e., cracking and the like) is significantly reduced and delayed, thereby resulting in acceptable pumptubes lifetimes. Generally, a pumptube of the present design using a polytetrafluoroethylene pumptube is expected to have a lifetime of about 20 to about 30 hours or greater when operating under high back-pressure conditions. When used in situations with little or no back-pressure (e.g., inlet and outlet pressure are essentially one atmosphere), lifetimes of up to about several hundred hours or greater are expected.




The pumptube is a relatively rigid and hard fluoroplastic and preferably is selected from the group consisting of perfluoroalkyoxy resin, fluorinated ethylene propylene, polychlorotrifluoroethylene, ethylene-chlorotrifluoroethylene copolymer, ethylene-tetrafluoroethylene copolymer, and polytetrafluoroethylene. The most preferred fluoroplastic for the tube is relatively rigid and hard polytetrafluoroethylene (PTFE). PTFE resin suitable for manufacture of PTFE tubing is available, for example, under the tradenames Algoflon (Ausimont USA Inc., Morristown, N.J.), Teflon (E.l. du Pont de Nemours & Co., Wilmington, Del.), Fluon (ICI Americas Inc., Wilmington, Del.), and Hostaflon (Hoechst Celanese Corp., Sommerville, N.J.). Suitable extruded PTFE tubing is generally available from, for example, Furon Co. (Laguna Niguel, Calif.), Norton Performance Plastics (Wayne, N.J.), Habia, AB (Sweden), and Zeus Industrial Products (Raritan, N.J.).




Generally the pumptube is formed from a relatively rigid and hard fluoroplastic tube, preferably a relatively rigid and hard polytetrafluoroethylene tube, with a Shore D hardness of about 25 to about 80, an outer diameter of about 4 to about 25 mm, an inner diameter of about 2 to about 22 mm, and a wall thickness of about 1 to about 2 mm. More preferably, the pumptube is formed from a relatively rigid and hard polytetrafluoroethylene tube with a Shore D hardness of about 50 to about 65, an outer diameter of about 12 to about 16 mm, an inner diameter of about 10 to about 13 mm, and a wall thickness of about 1 to about 1.5 mm. “Relatively rigid and hard” is intended to describe a pumptube which can still be flexed or bent but tends to return to its original shape, which retains its overall shape and especially the flattened, oval-like shape in the pumping section after use, and which requires significant force to occlude the fluid passageway in the pumping section.




Of course, the dimensional ranges given above for the pumptube relates to the tube before forming and shaping the pumping section


14


and to the unshaped portion of the completed pumptube (i.e.,


12


A and


12


B; see also FIG.


2


D). The pumptube, including the pumping section


14


, is formed and shaped to produce an oval-like or U-shaped pumptube with an oval-like fluid passageway


16


as shown in FIG.


2


. The overall shape to the pumptube is designed to fit into the pumptube passageway of the peristaltic pump.

FIG. 2

illustrates an overall U-shape which is designed to fit the pumptube passageway of the peristaltic pump of FIG.


1


. Of course, other overall shapes can be used so long they are adapted to the specific pumptube passageway in the peristaltic pump. As noted above, it is generally preferred that the major diameter of the fluid passageway in the pumping section is at least 3 times, and more preferably at least 5 times, greater than the minor diameter. Generally the minor diameter of the fluid passageway in the pumping section is in the range of about 0.1 to about 4 mm, and preferably in the range of about 0.15 to about 3 mm. Generally the major diameter of the fluid passageway in the pumping section is in the range of about 0.5 to about 30 mm, and preferably in the range of about 3 to about 20 mm. Generally the outside, cross-sectional dimensions of the pumptube in pumping section (i.e.,

FIG. 2B

) are about 2 to about 18 mm by about 6 to about 40 mm.




One especially preferred pumptube is constructed with a polytetrafluoroethylene tube having an inner diameter of about 6 mm, an outer diameter of about 8 mm, and a wall thickness of about 1 mm. Preferably, the flattened, shaped pumping section of such a pumptube has an outside, cross-sectional dimension of about 5 mm by about 10 mm and an oval-shaped fluid passageway of about 1 mm (minor diameter) by about 6 mm (major diameter). A second especially preferred pumptube is constructed from a polytetrafluoroethylene tube having an inner diameter of about 16 mm, an outer diameter of about 19 mm, and a wall thickness of about 1.5 mm. Preferably, the flattened, shaped pumping section of such a pumptube has an outside, cross-sectional dimension of about 14 mm by about 24 mm and an oval-shaped fluid passageway of about 2 mm (minor diameter) by about 20 mm (major diameter).




Compressing the flattened, oval-shaped pumping section


14


(i.e., moving from the uncompressed state of

FIG. 2B

to the compressed state of

FIG. 2C

) generally requires much higher compression pressures than conventional pumptubes. For example, compression of a representative pumptube of

FIG. 1

having the dimensions described in the preceding paragraph will generally require a force of about 100 to about 600 pounds to fully occlude an empty fluid passageway. Based on an estimate of the contact area between the pumptube and the pressure roller, a force of about 100 pounds for full occlusion is estimated to be equivalent to about 1000 pounds per square inch. For comparison purposes, only a force of about 5 to about 20 pounds (equivalent to about 50 to about 200 pounds per square inch) would be required to fully occlude the fluid passageway of an empty conventional flexible pumptube of comparable dimensions.




The pumptubes of the present invention can generally be used in peristaltic pumps of conventional design so long as the pump head components are modified to accommodate and accept the present pumptubes and roller strap. The shaped and flattened portion of the pumptube must, of course, conform to the pumptube passageway in the peristaltic pump. The rotor and pressure rollers in the peristaltic pump must accommodate, or be modified to accommodate, the higher pressures generally required for the rigid pumptubes of this invention. In addition, the peristaltic pump preferably is modified or designed to easily accept the pumptube. Due to the rigid nature of the present pumptubes, they cannot be easily threaded through the pumptube passageway as can the flexible pumptubes of the prior art. Rather, the peristaltic pump preferably is designed to allow the rigid pumptubes to be easily inserted and mounted into the pumptube passageway and then easily engaged in the pumping position. In

FIG. 1

, the retraction or movement of slidable member


32


towards the adjustment assembly


40


allows the pumptube to be easily inserted in the peristaltic pump.




Peristaltic pumps having designs other those shown in

FIGS. 1 and 4

can, of course, be used with the pumptubes of this invention. The pumptubes used, however, should be shaped to fit the specific pumptube passageway of the particular peristaltic pump and could, therefore, be of very different overall shapes and configurations than the U-shaped pumptube shown in FIG.


2


. The cross sectional areas in the non-pumping and pumping sections of the pumptube would, however, be similar to those shown in FIG.


2


. In addition, and preferably, the peristaltic pump should allow, or provide for, the pumptube to be easily inserted and removed. In addition to the peristaltic pumps shown in

FIGS. 1 and 4

, a pump design as shown in, for example, U.S. Pat. No. 5,082,429 (Jan. 21, 1992), which is hereby incorporated by reference, could be used with the appropriately-shaped pumptubes and roller straps of this invention. The pump design can incorporate a caming or locking mechanism to facilitate opening and closing of the pump and, therefore, insertion and removal of the pumptube. Although not preferred, pump designs which require the pump housing to be disassembled to insert and remove the pumptube can be used if desired. By modifying the overall shape of the pumptube and providing for higher occlusion pressures, peristaltic pumps having other designs and/or configurations can employ the rigid, relatively non-flexible, shaped pumptubes and roller straps of this invention.




As detailed above, the rigid pumptube of the present invention are shaped to conform to, and fit within, the pumptube passageway so that the pressure rollers contact the roller strap and then compress the flattened side of the flattened, oval-like shape forming the pumping section. The process of preparing the pumptubes of this invention preferably involves two stages using the fixtures illustrated in

FIGS. 5 and 6

. Using the fixture illustrated in

FIG. 5A

, the flattened portion or pumping section is formed first. Generally, a rigid tube or blank of the desired fluoroplastic material is inserted into vice


200


(in the open position). The vice


200


consists of upper and lower clamping surfaces


202


and


204


, upper and lower jaw members


206


and


208


, and clamping members


210


(shaft with threads


214


at the distal end) and


212


(rotatable handle). The vice is then tightened to form the flattened portion


14


having fluid passageway


16


. The width of the clamping surfaces should be sufficient to provide the desired length for the pumping section. Preferably, the flattened portion is formed at or near ambient temperature. Preferably, the upper and lower clamping surfaces


202


and


204


are formed from relatively soft and compressible materials (e.g., wood, and more preferably a soft wood such as pine) to avoid damaging the outer surfaces of the pumptube as the flattened section is formed. Of course, as those skilled in the art will realize, other vices or similar fixtures could be used.




Generally, the flattened section is formed by simply compressing the section of the tube within the vice. Preferably, the pumping section is essentially fully compressed with fixture


200


; full or essentially full compression can be determined by simply blowing into the tube. Once essentially fully compressed, the tube is held in the compressed state for a relatively short time (i.e., about 1 to about 10 minutes) and then released from the vice. After letting the tube expand or relax after the vice treatment (i.e., to achieve the cross-section shown in FIG.


2


B), the tube can then be further shaped to provide the desired overall shape to fit the peristaltic pump; in the case of the peristaltic pump shown in

FIG. 1

, the desired overall shape is a U-shaped configuration.




To form the desired overall shape for the pumptube, the blank with the flattened pumping section (obtained using the fixture shown in

FIG. 5

or similar tool) is heated to increase the malleability of the fluoroplastic material to be able to form it in the desired shape. Generally a temperature of about 75 to about 100° C. should be sufficient. Of course, as one skilled in the art will realize, the optimal temperature to which the blank should be heated will depend on a number of factors (e.g., overall size of tube, thickness of tube, length of pumping section, overall shape desired, and the like) and can best be determined experimentally for a given configuration. Once heated, the blank is immediately (i.e., generally within a minute or less) placed in an appropriate shaping fixture. The shaping fixture should approximate the shape of the pumptube passageway in the peristaltic pump which is to be used. The fixture


300


shown in

FIG. 6

is designed to provide pumptubes suitable for use in the peristaltic pumps shown in

FIGS. 1 and 4

. Of course, different peristaltic pump designs will necessitate different fixture designs. Additionally, the overall shape and construction of the fixtures are not critical so long as they can shape and form the pumping section into the desired flattened and oval-like shape and the overall pumptube into the approximate configuration of the pumptube passageway of the peristaltic pump to be used.




The fixture


300


shown in

FIGS. 6A and 6B

consists of a male member


304


with a shaping and forming surface


312


and a mated female member


306


with a shaping and forming surface


314


. When in their mated position, members


304


and


306


, through their respective shaping and forming surfaces


312


and


314


, form a passageway


306


of the desired geometry. The passageway


306


in

FIG. 6

is U-shaped and is of the same general geometry as the pumptube passageway formed in the peristaltic pumps of

FIGS. 1 and 4

. Members


304


and


306


also have guide or alinement members


313


(e.g., a pin or other obtrusion in one member and a matching receiving opening or slot in the other member). Members


304


and


306


also have a clamping assembly


310


whereby the members


304


and


306


can be locked together. At least the shaping and forming surfaces


312


and


314


of members


304


and


302


, respectively, which form the passageway


306


are preferably of a relatively soft and compressible material (e.g., wood and more preferably a soft wood such as pine) to prevent damage to the pumptube during the forming or shaping operation.




To form the shaped pumptube, the heated blank with the flattened pumping section is placed between members


302


and


304


in the shaping fixture so as to fit within the passageway


306


. As shown in

FIG. 5

, the passageway


306


can be formed by matching cavities in the members


302


and


304


; alternatively, the passageway


306


can be formed completely in either member


302


or


304


. The members


302


and


304


are then quickly brought into their mated position (as shown in

FIG. 6A

) so as to contain the pumptube blank in the passageway


306


; the two members


302


and


304


are then locked into place using clamping assembly


310


. Other clamping assembles (such as, for example, clamps, levers, caming mechanisms, air cylinders, solenoid pistons, and the like) can be used. The now formed pumptube is allowed to cool within the clamped fixture.




Of course, it is necessary to maintain the desired fluid passageway (


16


in

FIG. 2B

) during the forming operation. An appropriately shaped core member (not shown) preferably is placed within the blank having a flattened pumping section before the blank is heated such that the heated blank with the heated core is then shaped in fixture


300


. The use of such a core helps to prevent obstructions (e.g., crimping or other blockages) within the fluid passageway. Such a core should approximate the desired fluid passageway


16


shape to help form the fluid passageway; of course, such a core should be removable once the pumptube is removed from the fixture. Alternatively, the fluid passageway


16


may be kept open using a pressurized gas (preferably an inert pressurized gas) or liquid (e.g., water) within the fluid passageway during the shaping operation. Generally pressurized gas at about 1 to about 3 atmospheres is sufficient.




It is preferred, especially when the pumptube will be used to pump sensitive or biological fluids, that any core used in preparing the pumptubes of this invention are selected to prevent contamination of the interior of the fluid passageway. Thus, for example in preparing a polytetrafluoroethylene pumptube, the core member can be one or more thin polytetrafluoroethylene tubes or other plastic tubes coated with polytetrafluoroethylene. If a pressured gas is used as the core material to prevent obstruction of the pumptube passageway, it is preferably an inert gas; if water is used, it should be suitably purified. As those skilled in the art will realize, pumptubes can be prepared without using a core member (or other comparable procedures) to prevent or reduce obstruction in the fluid passageway. Such pumptubes, however, are likely to provide less uniform pumping characteristics, reduced pumping rates, and reduced lifetimes. Thus, pumptubes prepared with such core members or using other comparable procedures are preferred.




The locked up fixture containing the pumptube is then allowed to cool to ambient temperatures at which point the pumptube is removed. After removal from the fixture (and, if used, removal of the core), the pumptube is ready for use. If the pumptube is to be stored for later use, it is preferably to effectively “lock” the pumptube in its desired form to prevent the pumptube from gradually losing its desired overall shape. The pumptube can be locked |using, for example, a rubber band, string, or similar connecting device to keep the pumptube legs in the desired position or shape. Alternatively, the formed pumptube can be packaged in a manner to maintain the desired shape; for example, a molded plastic container that has a cavity similar to the pumptube shape could be used.




Of course other methods of forming the pumptubes of this invention can be used if desired. For example, a pumptube blank could be placed within a suitable peristaltic pump and then successively bent around the roller strap-covered pressure rollers to obtain the desired basic U-shape. The flattened portion of the pumptube can then be formed directly in the peristaltic pump by slowly tightening the occlusion bed


38


onto the pumptube to reach complete or essentially complete occlusion while the pump is operated. Preferably a pressurized gas or liquid (e.g., water) is passed through the pumptube as the occlusion bed is tightening onto the pumptube and is continued for about 0.5 to about 1 hour. Alternatively, the basic U-shape can e formed in a fixture similar to that shown in

FIG. 6A

using essentially the same procedure as described above. Thus, for example, a portion of a pumptube blank, preferably with a removable core in place, could be heated in hot water (generally about 75 to about 100° C.) and then very quickly placed in the fixture to form the desired overall shape (e.g., U-shaped). Once the blank is cooled to room temperature, it could be placed in an operating peristaltic to form the desired flattened portion by slowly tightening the slidable member


32


onto the pumptube to reach complete or essentially complete occlusion while the pump is operated. Preferably a pressurized gas or liquid (e.g., water) is passed through the pumptube as the occlusion bed is tightening onto the pumptube and is continued for about 0.5 to about 1 hour. As those skilled in the art will realize, these alternative forming methods can result in microscopic cracking or other damage, especially at both ends of the flattened pumping section of the pumptube. Thus, the pumptube formation method using fixtures as illustrated in

FIGS. 5 and 6

is generally preferred.




The embodiments and drawings described and discussed above are intended to illustrate the present invention and not to limit the scope of the invention which is defined in the appended claims.



Claims
  • 1. A peristaltic pump for transporting fluids, said peristaltic pump comprising:(a) a pump housing containing a pumptube passageway for receiving a pumptube having inlet and outlet ends extending outside the pump housing; (b) a plurality of pressure rollers rotably mounted within the pump housing to in turn roll along a pumping section of the pumptube so as to transport fluid from the inlet end to the outlet end of the pumptube; (c) guide cams attached to the pump housing at respective ends of the pumping section for guiding the inlet and outlet ends of the pumptube out of the pump housing; (d) and an inelastic strap biased against the guide cams and the pressure rollers along the pumping section of the pumptube to prevent excessive expansion of the pumptube between the pressure rollers at the outlet end when exposed to a counter pressure; wherein at least the pumping section of the pumptube comprises a single rigid fluoroplastic tubing preformed to fit within the pumptube passageway such that the pumptube within the pumping section is flattened into an oval-like shape with an oval-shaped fluid passageway such that the pressure rollers compress the pumping section of the pumptube essentially along the flattened side of the oval-like shape without contacting the pumping section.
  • 2. The peristaltic pump as defined in claim 1 further comprising a biasing assembly to bias the strap against the pressure rollers.
  • 3. The peristaltic pump as defined in claim 2, wherein the biasing assembly contains a spring to bias the strap against the pressure rollers.
  • 4. A peristaltic pump for transporting fluids, said peristaltic pump comprising(a) a pump housing containing a pumptube passageway; (b) a pumptube to fit within the pumptube passageway, the pumptube having inlet and outlet ends extending outside the pump housing, a pumping section contained within the pumptube passageway, and a fluid passageway extending through the pumptube from the inlet end to the outlet end; (c) a plurality of pressure rollers rotatably mounted within the housing, whereby each roller in turn compresses the pumping section of the pumptube contained within the pumptube passageway so as to transport fluid from the inlet end to the outlet end of the pumptube; (d) a first guide cam attached to the pump housing to support the pumping section of the pumptube adjacent to the outlet end; and (e) a strap mounted between the plurality of pressure rollers and the pumping section of the pumptube and between the first guide cam and the outlet end of the pumping section of the pumptube so that the pressure rollers are able to compress the pumping section without directly contacting the pumping section; wherein at least the pumping section of the pumptube comprises a single rigid fluoroplastic tubing preformed to fit within the pumptube passageway such that the pumptube within the pumping section is flattened into an oval-like shape with an oval-shaped fluid passageway such that the pressure rollers compress the pumping section of the pumptube essentially along the flattened side of the oval-like shape without contacting the pumping section.
  • 5. The peristaltic pump as defined in claim 4 further comprising a biasing assembly to bias the strap against the pressure rollers and the first guide cam.
  • 6. The peristaltic pump as defined in claim 5, wherein the biasing assembly contains a spring to bias the strap against the pressure rollers and the first guide cam.
  • 7. The peristaltic pump as defined in claim 6, wherein a second guide cam is attached to the pump housing to support the pumping section of the pumptube adjacent to the inlet end, such that the roller strap is also mounted between the second guide cam and the inlet end of the pumping section of the pumptube.
  • 8. The peristaltic pump as defined in claim 5, wherein the biasing assembly contains a take-up device to bias the strap against the pressure rollers and the first guide cam and wherein the strap is a continuous loop.
  • 9. The peristaltic pump as defined in claim 8, wherein a second guide cam is attached to the pump housing to support the pumping section of the pumptube adjacent to the inlet end, such that the roller strap is also mounted between the second guide cam and the inlet end of the pumping section of the pumptube.
  • 10. The peristaltic pump as defined in claim 5, wherein a second guide cam is attached to the pump housing to support the pumping section of the pumptube adjacent to the inlet end, such that the roller strap is also mounted between the second guide cam and the inlet end of the pumping section of the pumptube.
  • 11. The peristaltic pump as defined in claim 5, wherein the pumptube is formed from a rigid polytetrafluoroethylene tube with a Shore D hardness of about 25 to about 80, an outer diameter of about 4 to about 25 mm, an inner diameter of about 2 to about 22 mm, and a wall thickness of about 1 to about 2 mm.
  • 12. The peristaltic pump as defined in claim 11, wherein the strap has a width essentially the same as the pressure rollers and wherein the strap is polyester or an aromatic polyamide.
  • 13. The peristaltic pump as defined in claim 12, wherein the pumptube is U-shaped.
  • 14. The peristaltic pump as defined in claim 13, wherein the number of pressure rollers is at least five.
  • 15. The peristaltic pump as defined in claim 12, wherein the oval-like fluid passageway in the pumping section of the pumptube has a minor diameter of about 0.1 to about 4 mm.
  • 16. The peristaltic pump as defined in claim 5, wherein the strap has a width essentially the same as the pressure rollers and wherein the strap is a polyester or an aromatic polyamide.
  • 17. The peristaltic pump as defined in claim 16, wherein the pumptube is U-shaped.
  • 18. The peristaltic pump as defined in claim 17, wherein the number of pressure rollers is at least five.
  • 19. The peristaltic pump as defined in claim 16, wherein the oval-like fluid passageway in the pumping section of the pumptube has a minor diameter of about 0.1 to about 4 mm.
  • 20. The peristaltic pump as defined in claim 4, wherein the pumptube is formed from a rigid polytetrafluoroethylene tube with a Shore D hardness of about 50 to about 65, an outer diameter of about 12 to about 16 mm, an inner diameter of about 10 to about 13 mm, and a wall thickness of about 1 to about 1.5 mm; wherein the strap has a width essentially the same as the pressure rollers; wherein the strap is polyester or an aromatic polyamide; wherein the pumptube is U-shaped; and wherein the number of pressure rollers is five to eight.
  • 21. A peristaltic pump for transporting fluids, said peristaltic pump comprising(a) a pump housing containing a pumptube passageway; (b) a pumptube having inlet and outlet ends extending outside the pump housing, a pumping section contained within the pumptube passageway, and a fluid passageway extending through the pumptube from the inlet end to the outlet end; (c) a plurality of pressure rollers rotatably mounted within the housing, whereby each roller in turn compresses the pumping section of the pumptube contained within the pumptube passageway so as to transport fluid from the inlet end to the outlet end of the pumptube; and (d) a strap mounted between the plurality of pressure rollers and the pumping section of the pumptube so that the pressure rollers are able to compress the pumping section without contacting the pumping section; wherein at least the pumping section of the pumptube comprises a single rigid fluoroplastic tubing preformed to fit within the pumptube passageway such that the pumptube within the pumping section is flattened into an oval-like shape with an oval-shaped fluid passageway such that the pressure rollers compress the pumping section of the pumptube essentially along the flattened side of the oval-like shape without contacting the pumping section.
  • 22. A pumptube system comprising a pumptube and a roller strap, which ystem is suitable for use in a peristaltic pump having a pumptube passageway and a plurality of pressure rollers for compressing the pumptube whereby a fluid can be transferred, wherein the pumptube comprises(a) inlet and outlet ends; (b) a pumping section located between the inlet and outlet ends; and (c) a fluid passageway extending through the pumptube from the inlet end to the outlet end; wherein at least the pumping section of the pumptube comprises a single rigid fluoroplastic tubing, wherein the pumptube is preformed to fit within the pumptube passageway such that the pumptube within the pumping section is flattened into an oval-like shape with an oval-like fluid passageway such that the pressure rollers compress the pumping section of the pumptube essentially along the flattened side of the oval-like shape; and wherein the roller strap comprises an inelastic material to be located between the pressure rollers and the pumping section of the pumptube so that the pressure rollers do not contact the pumping section of the pumptube when the pumping section is compressed.
  • 23. The system as defined in claim 22, wherein the pumptube is formed from a rigid polytetrafluoroethylene tube with a Shore D hardness of about 25 to about 80, an outer diameter of about 4 to about 25 mm, an inner diameter of about 2 to about 22 mm, and a wall thickness of about 1 to about 2 mm; and wherein the strap is polyester or an aromatic polyamide.
  • 24. The system as defined in claim 23, wherein the oval-like fluid passageway has a minor diameter of about 0.1 to about 4 mm; and wherein the pumptube is U-shaped.
  • 25. The system as defined in claim 22, wherein the pumptube is formed from a rigid polytetrafluoroethylene tube with a Shore D hardness of about 50 to about 65, an outer diameter of about 4 to about 25 mm, an inner diameter of about 2 to about 22 mm, and a wall thickness of about 1 to about 1.5 mm; wherein the strap has a width essentially the same as the pressure rollers; wherein the strap is polyester or an aromatic polyamide; wherein the pumptube is U-shaped; and wherein the number of pressure rollers is five to eight.
  • 26. A method of preparing a pumptube suitable for use in a peristaltic pump having a pumptube passageway, a plurality of pressure rollers, an inelastic strap located between the pressure rollers and the pumptube, wherein the pressure rollers, through pressure transferred though the strap, compress the pumptube via the strap without directly contacting the pumptube, whereby a fluid can be transferred, said method comprising(a) forming a length of a rigid fluoroplastic tubing having a fluid passageway extending throughout the length of the rigid fluoroplastic tubing; (b) placing a central portion of the length of rigid fluoroplastic tubing in a clamping fixture capable of compressing the central portion; (c) compressing the central portion of the rigid fluoroplastic tubing at or near room temperature using the clamping fixture to form a fully compressed and flattened section in the central portion; (d) allowing the fully compressed and flattened section to expand to form a flattened, oval-like shaped pumping section with an oval-like fluid passageway therein; and (e) forming the rigid fluoroplastic tubing containing the flattened, oval-like fluid passageway into a shape to fit within the pumptube passageway of the peristaltic pump.
  • 27. The method as defined in claim 26, wherein the rigid fluoroplastic tubing containing the flattened, oval-like fluid passageway is formed into the shape to fit within the pumptube passageway of the peristaltic pump by a method comprising(a) heating at least the pumping section of the rigid fluoroplastic tubing to a temperature sufficient to increase the malleability of the rigid fluoroplastic tubing; (b) placing the heated rigid fluoroplastic tubing in a molding fixture capable of molding the pumptube into the shape to fit within the pumptube passageway of the peristaltic pump; (c) molding the pumptube into the shape to fit within the pumptube passageway without obstructing the oval-like fluid passageway; and (d) allowing the pumptube to cool to or near ambient temperature within the molding fixture; whereby the pumptube fitting within the pumptube passageway of the peristaltic pump is obtained.
  • 28. The method as defined in claim 27, wherein the pumping section of the rigid fluoroplastic tubing is heated to about 75 to about 100° C. to increase the malleability of the rigid fluoroplastic tubing.
  • 29. The method as defined in claim 28, wherein a core is fitted into the oval-like fluid passageway before the rigid fluoroplastic tubing is heated to about 75 to about 100° C. to increase the malleability of the rigid fluoroplastic tubing, wherein the core remains within the oval-like passageway at least through the molding step, whereby the core prevents the obstruction of the oval-like fluid passageway during the molding step.
  • 30. The method as defined in claim 29, wherein the rigid fluoroplastic tubing is a rigid polytetrafluoroethylene tube with a Shore D hardness of about 25 to about 80, an outer diameter of about 4 to about 25 mm, an inner diameter of about 2 to about 22 mm, and a wall thickness of about 1 to about 2 mm; and wherein the pumptube is U-shaped to fit within the pumptube passageway of the peristaltic pump.
  • 31. The method as defined in claim 28, wherein a pressurized gas or liquid is passed through the oval-like passageway during at least the molding step to prevent the obstruction of the oval-like passageway during the molding step.
  • 32. The method as defined in claim 31, wherein the rigid polytetrafluoroethylene tube has a Shore D hardness of about 50 to about 65, an outer diameter of about 12 to about 16 mm, an inner diameter of about 10 to about 13 mm, and a wall thickness of about 1 to about 1.5 mm.
  • 33. The method as defined in claim 31, wherein the pressurized gas is used to prevent the obstruction and wherein the pressurized gas is at a pressure of about 1 to about 3 atmospheres.
  • 34. The method as defined in claim 31, wherein the liquid is used to prevent the obstruction and wherein the liquid is water.
  • 35. The method as defined in claim 34, wherein the rigid polytetrafluoroethylene tube has a Shore D hardness of about 50 to about 65, an outer diameter of about 12 to about 16 mm, an inner diameter of about 10 to about 13 mm, and a wall thickness of about 1 to about 1.5 mm.
  • 36. The method as defined in claim 31, wherein the rigid fluoroplastic tubing is a rigid polytetrafluoroethylene tube with a Shore D hardness of about 25 to about 80, an outer diameter of about 4 to about 25 mm, an inner diameter of about 2 to about 22 mm, and a wall thickness of about 1 to about 2 mm; and wherein the pumptube is U-shaped to fit within the pumptube passageway of the peristaltic pump.
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