Perspiration sensor

Information

  • Patent Grant
  • 10398343
  • Patent Number
    10,398,343
  • Date Filed
    Tuesday, March 1, 2016
    8 years ago
  • Date Issued
    Tuesday, September 3, 2019
    5 years ago
Abstract
A moisture sensor includes a pair of electrode plates separated by a moisture absorbent material that forms the dielectric of a capacitive sensor. As the absorbent dielectric material absorbs moisture, such as perspiration, the capacitance of the sensor changes reflecting a quantitative measure of perspiration absorbed. The sensor can be stabilized by capacitively coupling the dielectric material to the skin of the user to improve sensor stability and noise rejection. The sensor can include a capacitive sensing integrated circuit that measures the capacitance of the sensor in close proximity to the electrodes to limit the introduction of noise.
Description
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH

Not Applicable


REFERENCE TO MICROFICHE APPENDIX

Not Applicable


BACKGROUND

Technical Field of the Invention


The present invention is directed to a moisture sensor and more specifically, to a perspiration sensor for quantitatively measuring levels of perspiration. In accordance with some embodiments, the perspiration sensor includes a capacitive sensor that can be coupled to the skin and utilize capacitance to measure perspiration. The perspiration sensor can be shielded and stabilized to reduce noise by electrically coupling the capacitor dielectric material to the skin.


Description of the Prior Art


The prior art perspiration sensors are generally related to devices for determining galvanic skin response. These devices involve the measurement of the electrical resistance of the skin, but do not provide a quantitative indication of the volume or level of perspiration over time.


SUMMARY

The present invention is directed to a method and system for obtaining a quantitative measurement of moisture, and more specifically, perspiration. Various embodiments of the invention utilize the dielectric properties of perspiration in a capacitive sensor that includes a pair of ground shielded parallel electrodes sandwiching a moisture absorbent dielectric material (e.g., a microfiber cloth). In accordance with some embodiments, the dielectric material can be electrically coupled (e.g., capacitively coupled) to the skin of the user to provide a more stable signal because the skin is capacitively coupled to earth ground which is weakly capacitively coupled to the ground of signal measurement circuit (e.g., the capacitance to digital signal converter integrated circuit). The method includes a providing a capacitor that includes a dielectric material that absorbs moisture (e.g., perspiration) in contact with the skin, wherein the capacitor includes one or more inlets that enable perspiration released from the skin to become absorbed by the absorbent dielectric material and electrically (e.g., capacitively) coupling the dielectric material to the body.


In accordance with the invention, the perspiration sensor can be constructed having three layers, a first or top layer, a second or middle layer and a third or bottom layer. The bottom layer can include an adhesive or other skin contacting material that maintains contact with and capacitively couples the sensor to the skin. The bottom layer and the top layer include the first and second electrode plates that form the capacitor with dielectric material surrounded by the middle layer sandwiched in between. The bottom layer, middle layer and top layer form a central chamber that encloses the dielectric material and positions it in a dielectric space between the first and second electrodes. The bottom layer can also include one or more pores, inlets or vents that enable perspiration released from the skin to enter central chamber and be absorbed by the dielectric material in the dielectric space. The bottom layer can also include a skin coupling electrode that becomes electrically coupled to the skin when the bottom surface of the bottom layer is adhered to or placed in contact with the skin. The skin coupling electrode can be electrically connected to the central chamber and the dielectric material. When the bottom surface includes an adhesive material, the skin coupling electrode capacitively couples the dielectric material in the central chamber to the skin to provide ground shielding adjacent to the electrodes to minimize environmental noise. In accordance with some embodiments of the invention, the dielectric material can be weakly but consistently (capacitively) coupled to earth ground through the skin.


Each of the layers can be formed from a rigid printed circuit board (PCB) or a flexible PCB, and each of the layers can be laminated together as is well known in the art. The dielectric material can be an absorbent material that rapidly replaces air with perspiration, such as a tufted microfiber cloth. The thickness of the middle layer can be selected to define and control the distance between the sensing electrode plates of the capacitor. In accordance with some embodiments, the middle layer includes a rigid material having a predefined thickness to tightly control the electrode plate spacing and slightly thinner than the thickness of the microfiber cloth causing portions of the cloth to extrude through the pores or inlets of the bottom layer facilitate moisture absorption.


In accordance with some embodiments of the invention, the device can further include a capacitance measurement integrated circuit (e.g., IC chip) mounted to the top layer that enables close proximity measurement of the change in capacitance of the sensor to minimize the introduction of noise. In this configuration, the measured capacitance can be transmitted (e.g., by wire or wirelessly) to a remote system for storing and/or analyzing the capacitance data and determining perspiration rates (e.g., volume and volume over time).


In accordance with some embodiments of the invention, the device can be fully or partially enclosed or encapsulated in polymer or elastomeric material (e.g. PDMS, or silicone) that protects the sensor from the environment. One or more of the layers can include one or more partially or fully enclosed anchor rings projecting from the perimeter of the device such that the polymer material passes through the opening in the anchor rings to more securely anchor the encapsulating material to the outside of the device.


In operation, the bottom of the device is coupled to the skin by an adhesive material and perspiration released by the skin passes through the inlets and become absorbed by the microfiber dielectric material. The capacitance of the first and second electrodes changes as the dielectric material absorbs perspiration. In addition, the bottom of the device includes a skin electrode that is electrically connected to the dielectric material and the central chamber. The skin electrode can be electrically connected to the middle layer by plated through holes or vias in the bottom layer. The vias in the middle layer can include electrodes that directly contact the dielectric material, enabling the dielectric material to be coupled (e.g., capacitively coupled) to the skin through the adhesive. The integrated circuit on the top layer includes a circuit that determines a measure of the capacitance between the first and second electrodes while the skin electrode serves to stabilize the capacitance measurement against noise.


These and other capabilities of the invention, along with the invention itself, will be more fully understood after a review of the following figures, detailed description, and claims.





BRIEF DESCRIPTION OF THE FIGURES

The accompanying drawings, which are incorporated into this specification, illustrate one or more exemplary embodiments of the inventions and, together with the detailed description, serve to explain the principles and applications of these inventions. The drawings and detailed description are illustrative, and are intended to facilitate an understanding of the inventions and their application without limiting the scope of the invention. The illustrative embodiments can be modified and adapted without departing from the spirit and scope of the inventions.



FIG. 1 is a photograph of a perspiration sensor according to an embodiment of the invention.



FIGS. 2A and 2B show diagrammatic views of a silicon encapsulated perspiration sensor according to an embodiment of the invention.



FIGS. 3A and 3B show diagrammatic views of a perspiration sensor according to some embodiments of the invention.



FIG. 4 shows an exploded isometric top view of a perspiration sensor according to an embodiment of the invention.



FIG. 5 shows an exploded isometric bottom view of a perspiration sensor according to an embodiment of the invention.



FIG. 6A shows an exploded cross-section view of a perspiration sensor according to an embodiment of the invention.



FIG. 6B shows a cross-section view of an assembled perspiration sensor according to an embodiment of the invention shown in FIG. 6A.



FIG. 7A shows a diagram of a perspiration sensor according to some embodiments of the invention, FIG. 7B shows a diagrammatic view of the middle layer according to an embodiment of the invention, and FIG. 7C shows a cutaway view of a perspiration sensor according to some embodiments of the invention with a portion of the encapsulation material removed.



FIGS. 8A and 8B show diagrams of dielectric material according to some embodiments of the invention.



FIGS. 9A and 9B show diagrams of electronic circuits for measuring the change in capacitance between the electrodes of a perspiration sensor according to some embodiments of the invention.



FIGS. 10A, 10B, 10C and 10D show graphs of performance data for 5 a perspiration sensor according to some embodiments of the invention.





DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS

The present invention is directed to methods and systems for obtaining a quantitative measurement of moisture. One specific application for the invention includes the detection and measurement of perspiration. For purposes of illustration, the invention is described herein in the context of measuring perspiration, however, embodiments of the invention can be used to measure other sources of moisture.


In accordance with some embodiments of the invention, the perspiration sensor includes a pair of ground shielded parallel electrodes sandwiching a moisture absorbent dielectric material (e.g., a microfiber cloth) that forms a capacitor. The sensor allows perspiration to become absorbed by moisture absorbent dielectric material which changes the dielectric constant the dielectric material and is reflected in the measured capacitance of the electrode plates of the perspiration sensor. In accordance with some embodiments of the invention, the dielectric material can be electrically coupled (e.g., capacitively coupled) to the skin of the user to provide for more stable signal measurement. In accordance with some embodiments of the invention, the absorbent dielectric material can be weakly (e.g., 10 pF or less) but consistently (e.g., up to 10% variation) coupled through the skin to earth ground which is weakly coupled to signal ground of capacitance measuring circuit. The method includes providing a capacitor that includes an exposed dielectric material that can absorb moisture (e.g., perspiration) produced by the skin. As perspiration is released from the skin and becomes absorbed by the absorbent dielectric material, the dielectric properties of the material between the electrode plates change resulting in a change in the capacitance of the perspiration sensor. An internal or external measurement component can be connected to the electrodes of the capacitor to measure the changes in capacitance of the perspiration sensor.


The dielectric properties of perspiration closely resemble that of saline which in turn closely resemble that of water. The dielectric constant of water is about 80 times that of air. An air capacitor formed by two parallel plates will increase capacitance significantly when air is replaced with water, saline, or perspiration. The approximate capacitance C of the parallel plates can be determined by






C
=


ɛ
0



ɛ
r



A
d







where A is the area of the electrode plate, d is the distance between the plates; ε0 is the dielectric constant of free space and εr is the relative dielectric constant of the material between the plates.


In accordance with the invention, the dielectric material can be selected to rapidly absorb the perspiration. In accordance with some embodiments of the invention, the dielectric material can have predefined wicking or absorbency properties that provide a desired level of perspiration absorption. In operation, the dielectric material is initially in a dry state and has dielectric properties similar to air and produces an initial capacitance level. As the dielectric material is exposed to moisture (e.g., perspiration) the moisture rapidly replaces the air, changing the dielectric properties of the dielectric material and the measured capacitance level of the sensor.


In accordance with some embodiments of the invention, the absorbent dielectric material can include a tufted microfiber cloth. This material has been found to have improved capillary suction and to diffuse perspiration faster and more uniformly than other materials as well as provides higher absorption densities. Other absorbent materials, such as cellulose paper, foamy elastomers, cotton, wool, air, and moisture wicking materials, can be used. The absorbent dielectric material can be configured to have a large surface area to volume ratio of the material that results in capillary suction causing the air filled space to become filled with environmental moisture or perspiration. A capacitance measuring circuit can be provided onboard or in close proximity to the capacitor sensor to minimize noise and convert the capacitance to a digital signal for transmission to a connected device.



FIGS. 1, 3A and 3B shows a moisture or perspiration sensor 100 according to various embodiments of the invention with the encapsulating polymer removed to provide a better view of the structure of the device. FIGS. 2A and 2B show diagrammatic views of a perspiration sensor 200 according to embodiments of the invention encapsulated in an encapsulating material, such as polymer material (e.g., silicone, PDMS, polyimide, TPE, PET, PVC, and MMA). The perspiration sensor 200 can include channels 210 that serve to guide moisture, such as perspiration, toward inlets in the perspiration sensor 200.


As shown in FIGS. 3A and 3B, the perspiration sensor 100 can be constructed from two or more layers of insulating or dielectric material (e.g., a first layer 110, a second layer 120 and the third layer 130). In accordance with some embodiments of the invention, each layer can include a non-conductive substrate (e.g. FR4 epoxy fiberglass, PDMS, or polyimide) having a conductive layer (e.g., copper and/or tin) on one or both surfaces of the substrate, such as a printed circuit board (PCB) or flexible PCB. In accordance with some embodiments of the invention, each layer can include a protective and/or insulating coating (e.g., solder mask coating) covering a portion or all of each surface of each layer. Each of the layers that make up the perspiration sensor 100 can be bonded together using well known adhesives (e.g., epoxy, polyimide, and/or silicone based adhesives). The surfaces of at least some of the layers can include exposed pads enabling electronic components such as integrated circuits, discrete components (e.g., resistors, capacitors, diodes and other passive devices) to soldered in place. The layers can also include vias or plated through holes that allow circuit traces to extend through the layer can make contact with circuit traces of the other layers. In accordance with some embodiments of the invention, some or all of the layers can include castellated vias on or extending from the external edges that provide for mechanical alignment and enable low temperature fabrication—the castellated vias are positioned away from central chamber and can be soldered without fear of melting or otherwise damaging the absorbent dielectric material.



FIG. 4 shows an exploded view of a perspiration sensor 100 according to some embodiments of the invention. In this embodiment, the perspiration sensor 100 includes a first or top layer 110, a second or middle layer 120 and the third or bottom layer 130. The first layer 110 includes a first electrode 112 on the underside of the first layer (hidden from view in FIG. 4, but shown in FIG. 5). The first layer 110 can also include circuit traces that enable a sensing integrated circuit 140 to soldered in place and electrically connected to the first electrode 112 and second electrode 134 and wires (not shown) that connect the perspiration sensor 100 to other devices. The third layer 130 includes one or more inlets 132 and the second electrode 134. The third layer 130 can also include a skin electrode 136 (hidden from view in FIG. 4, but shown in FIG. 5) and an adhesive material covering the skin electrode 136 to adhere the perspiration sensor 100 to a surface such as a skin surface. The second layer 120 forms a ring 122 that at least partially surrounds or encloses the dielectric material 124 in the dielectric space defined by the central chamber 26. When the three layers are bonded together, they form a central chamber 126 which encloses the dielectric material 124 (e.g., the moisture absorbent material). In accordance with some embodiments of the invention, the thickness of each layer can be selected to minimize the overall thickness of the sensor to improve user comfort. Thus, the first layer 110 and the third layer 130 can be thicker or thinner than the middle layer 120. Alternatively, each of the layers can have the same or different thicknesses. In accordance with some embodiments, the sensor detection area, defined by the inlets 132 can cover an area of 1 cubic centimeter and provide an average pore density of 50 pores (e.g., in the arm pit).



FIG. 5 shows an exploded bottom view of the perspiration sensor 100 (e.g., showing the third layer 130 on top). As shown in FIG. 5, the third layer 130 can include a skin electrode 136 on the outer surface thereof. The skin electrode 136 can be provided in the form of a ring, as shown, or as a set of interconnected contact points over the outer surface of the third layer 130. In accordance with some embodiments, the skin electrode 136 can be electrically connected to the dielectric material 124 in the central chamber 126 of the perspiration sensor 100 by extending circuit traces around or vias through the third layer 130 to the middle layer 120 and in contact with the dielectric material 124. In accordance with other embodiments, the skin electrode 136 can be electrically connected to the dielectric material 124 by circuit traces or wires that extend from the inner surface of the third layer 130 into the central chamber 126. The skin electrode 136 can be covered with a solder mask or other insulating material (e.g., skin adhesive tape). When the perspiration sensor 100 is adhered or placed in contact with the skin, the skin electrode 136 capacitively couples the dielectric material 124 to the skin.



FIG. 6A shows an exploded cross-section view and FIG. 6B shows an assembled cross-section view of a perspiration sensor 100 according to some embodiments of the invention. In this embodiment, an adhesive layer 150 adheres the third layer 130 of the perspiration sensor 100 to the surface of the skin 160 enabling the device to measure perspiration. The perspiration sensor 100 includes a first layer 110, second layer 120 and a third layer 130. The first electrode 112 is formed on the inner surface of the first layer 110 and the second electrode 134 is formed on the inner surface of the third layer 130. A mask 114 on the first layer and a mask 138 on third layer can be included to electrically insulate the first electrode 112 and the second electrode 134 from the dielectric material 124 while enabling the dielectric material 124 to be in intimate contact with the first electrode 112 and the second electrode 134 while preventing the moistened dielectric material from shorting the first electrode to the second electrode. The insulating masks 114 and 138 can be formed from any solder mask insulating material (e.g., a layer or film of epoxy or UV cured polymer or resin). The second layer 120 is bonded between the first layer 110 and the third layer 130 supporting the first electrode 112 at predefined distance with respect to the second electrode 134 and forming the central chamber 126 that encloses the moisture absorbent dielectric material 124. The third layer 130 includes one or more inlets 132 that allow the moisture (e.g., perspiration) to enter the central chamber 126 and become absorbed by the moisture absorbent dielectric material 124 as well as to allow air initially contained within the moisture absorbent dielectric material 124 to escape. As shown in FIG. 6B, when the layers are bonded together, the moisture absorbent dielectric material 124 can become partially or fully extruded through the inlets 132 to facilitate moisture absorption. In accordance with some embodiments, an outlet can be provided through the middle layer 120 or the first layer 110 to enable air initially contained within the moisture absorbent dielectric material 124 to escape. The perspiration from skin 160 enters the inlets 132 and is absorbed by the moisture absorbent dielectric material 124.


As shown in FIGS. 6A and 6B, the third layer 130 includes one or more vias or plated through holes that electrically connect the skin electrode 136 to the inner surface of the third layer 130 and after assembly, make electrical contact with an inner trace or electrode 122 on the middle layer 120. The inner electrode 122 can extend into the central chamber 126 and make contact with the moisture absorbent dielectric material 124. In some embodiments of the invention, all or a portion of the inner surface 128 of the middle layer 120 can include a conductive material (e.g., copper or tin) that makes contact with the moisture absorbent dielectric material 124.



FIG. 7A shows a perspective view of a perspiration sensor 100 according to some embodiments of the invention and FIG. 7B shows a diagrammatic view of the middle layer 120. In these embodiments, the first layer 110, the middle layer 120 and the third layer 130 each include pads 122, 236 and plated through holes or partial holes or vias 228 that enable circuit traces to extend between layers. Solder can be applied to the plated through holes or vias 228 to create a physical connection between the layers and an electrical connection between the pads 122, 236 on the outside surfaces of the sensor 100 and the dielectric space defined by the central chamber 126. In some embodiments, the third layer 130 can include pads (not shown) that serve as the skin electrode 136 and can be electrically connected to circuit traces on the middle layer 120 and the first layer 110 soldering together the vias 228. Similar vias 226 can be provided on the inner surface of the middle layer 120 and connected by circuit traces 222 to one or more of the vias 228 to provide an electrical connection between the skin electrode 136 and the moisture absorbent dielectric material 124.


In accordance with some embodiments of the invention, the perspiration sensor 100 can also include one or more anchor rings 220 that project from the peripheral edge of the device as shown in FIGS. 7A and 7B. The anchor rings 220 serve to provide features in the peripheral structure of the sensor device to aid in anchoring the device in the encapsulating material such as silicone, PDMS, polyimide during assembly. FIG. 7C shows a partially cut away view of a perspiration sensor 100 according to some embodiments of the invention. In this embodiment, the vias 228 are shown along the outer surface of the sensor 100 and the anchor rings 220 are shown extending from the outer peripheral surface of the sensor 100. In some embodiments, the encapsulating material 205 can at least partially extend into the openings of the anchor rings 220.



FIGS. 8A and 8B show photos and diagrams of microfibers. Microfiber based materials provide for improved absorption of moisture. In some embodiments, the microfibers can be split microfibers which have an X or asterisk shaped cross-section as shown in FIG. 8A. This structure results in the formation of microchannels in the fibers that help absorb moisture (e.g., by capillary action) better than regular solid fibers. As shown in FIG. 8B, these microfibers can be loosely woven into a tufted cloth that provides good absorption of moisture.


In accordance with some embodiments, the perspiration sensor can include a capacitive sensor signal measuring integrated circuit that accurately measures the capacitance or capacitive signal and converts it to a digital signal for transmission to a remote device. In accordance with some embodiments of the invention, the capacitive sensor signal measuring integrated circuit can include a ZSSC3123 integrated circuit (ZMDI, Dresden, Germany and Milpitas, Calif.). FIG. 9A shows a block diagram of the integrated circuit. FIG. 9B shows a diagram of a charge balancing circuit for converting the analog capacitance signal to a digital signal. The circuit includes a 1st order charge-balancing capacitance-to-digital converter. Capacitor CB can be a fixed reference capacitor internal to the IC itself. The measurement determines the amount of time it takes each cycle to charge and discharge the reference capacitor. The capacitor CA is driven by a square wave voltage with excitation frequency in the 100 kHz range to prevent aging effects that occur when driven by a DC signal. The output signal generated by this circuit is a ratio of sensor capacitance to reference capacitance.



FIG. 10A shows a sensitivity graph for a capacitive perspiration sensor according to the invention. As shown in FIG. 10A, the sensitivity is higher (e.g., 2.5 pF/μL) at lower moisture levels and decreases (e.g., to 1.2 pF/μL) as the level of moisture increases.



FIG. 10B shows a responsivity graph for a capacitive perspiration sensor according to the invention. The graph in FIG. 10B shows the response of the capacitive perspiration sensor according to the invention over time at 5 different moisture levels (e.g., 0.1 μL, 0.2 μL, 0.5 μL, 1.0 μL, and 2.0 μL).



FIG. 10C shows the effect of shielding (e.g., capacitive coupling the dielectric to the skin) on a capacitive perspiration sensor according to the invention. As shown in FIG. 10C, an unshielded capacitive perspiration sensor exhibits signal spikes upon contact whereas the shielded capacitive perspiration sensor according to the invention does not.



FIG. 10D shows a comparison of the range and sensitivity of shielded and unshielded capacitive perspiration sensors according to the invention. As shown in FIG. 10D, the shielded sensor has approximately the same range and sensitivity as an unshielded sensor.


In accordance with some embodiments of the invention, the perspiration sensor can be part of system that quantitatively measures perspiration of a user in real time. The sensor can be connected to a data-logging hub (e.g. BioStamp TM by MC10 Inc., a smartphone or data recorder). The perspiration sensor can measure a change in capacitance over time and calculate perspiration moisture volume using a predetermined calibrated curve. The data logging hub can include a computer processor and associated memory that can communicate with the perspiration sensor to receive sensor data. The data logging hub can include additional wired or wireless communication components to enable the sensor data to be stored in a remote database or processed by a remote data processing system.


While some embodiments of the present invention are described in the context of a perspiration sensor, the invention can be used for measuring moisture in other applications. In some embodiments, the moisture sensor can be used to measure perspiration to test the efficacy of anti-perspirant products. In other applications, the moisture sensor can be installed in a helmet worn by an athlete, a soldier or a fighter pilot as well as other areas of the body to provide continuous physiological monitoring, for example, for health, wellness, hydration and/or stress monitoring. In accordance with some embodiments, the central chamber or an adjacent collection chamber can include analyte sensors and/or assays to detecting the presence and/or quantity of components of the absorbed perspiration. For example, a sodium sensor can be included for diagnosis of cystic fibrosis.


Other embodiments are within the scope and spirit of the invention. For example, due to the nature of hardware and software, functions described above can be implemented using software, hardware, firmware, hardwiring, or combinations of any of these. Features implementing functions may also be physically located at various positions, including being distributed such that portions of functions are implemented at different physical locations.


Further, while the description above refers to the invention, the description may include more than one invention.

Claims
  • 1. A perspiration sensor comprising: a first electrode positioned a predefined distance from a second electrode defining a dielectric space between the first electrode and the second electrode;a moisture absorbent dielectric material positioned in the dielectric space between the first electrode and the second electrode;at least one inlet enabling moisture from outside the dielectric space to enter the dielectric space and become absorbed by the moisture absorbent material;a skin electrode and an adhesive layer configured for adhering the skin electrode to a skin portion of a user whereby the skin electrode is capacitively coupled to the skin portion of the user, and wherein the skin electrode is electrically connected to the moisture absorbent material;a polymer material encapsulating at least a portion of the perspiration sensor; andwherein the perspiration sensor includes one or more loops extending from a peripheral edge of the perspiration sensor and the polymer material at least partially extends into an opening in at least one loop.
  • 2. The perspiration sensor according to claim 1 wherein the moisture absorbent material includes a tufted microfiber cloth.
  • 3. The perspiration sensor according to claim 1 wherein the moisture includes perspiration.
  • 4. The perspiration sensor according to claim 1 wherein the polymer material forms channels in at least one surface of the perspiration sensor to direct moisture to the at least one inlet of the perspiration sensor.
  • 5. The perspiration sensor according to claim 1 wherein the polymer material includes silicone.
  • 6. A perspiration sensor comprising: a first electrode positioned a predefined distance from a second electrode defining a dielectric space between the first electrode and the second electrode wherein: the first electrode is mounted to a non-conducting first substrate layer;the second electrode is mounted to a non-conducting third substrate layer; andthe first substrate layer is separated from the third substrate layer by a non-conducting second substrate layer;a moisture absorbent dielectric material positioned in the dielectric space between the first electrode and the second electrode;at least one inlet enabling moisture from outside the dielectric space to enter the dielectric space and become absorbed by the moisture absorbent material; anda skin electrode and an adhesive layer configured for adhering the skin electrode to a skin portion of a user whereby the skin electrode is capacitively coupled to the skin portion of the user, andwherein the second substrate layer includes a third electrode and the third electrode connects the skin electrode to the moisture absorbent material in the dielectric space.
  • 7. The perspiration sensor according to claim 6 wherein the second substrate layer has a predefined thickness that defines a distance between the first electrode and the second electrode.
  • 8. The perspiration sensor according to claim 6 wherein the non-conducting first substrate layer includes an epoxy fiberglass material, the non-conducting second substrate layer includes an epoxy fiberglass material, and the non-conducting third substrate layer includes an epoxy fiberglass material.
  • 9. The perspiration sensor according to claim 6 wherein the non-conducting first substrate layer includes a polyimide material, the non-conducting second substrate layer includes a polyimide material, and the non-conducting third substrate layer includes a polyimide material.
  • 10. The perspiration sensor according to claim 6 wherein the second substrate layer forms a ring that defines the dielectric space.
  • 11. The perspiration sensor according to claim 6 wherein at least one of the first substrate layer and the second substrate layer include an outlet to enable air contained in the dielectric space to escape as moisture enters the dielectric space.
  • 12. The perspiration sensor according to claim 6 further comprising an integrated circuit coupled to the first substrate layer and electrically connected to the first electrode and the second electrode; and wherein the integrated circuit receives a signal from the first electrode and the second electrode and outputs a digital signal as a function of the received signal.
  • 13. A perspiration sensor comprising: a first electrode positioned a predefined distance from a second electrode defining a dielectric space between the first electrode and the second electrode wherein: the first electrode is mounted to a non-conducting first substrate layer;the second electrode is mounted to a non-conducting third substrate layer; andthe first substrate layer is separated from the third substrate layer by a non-conducting second substrate layer;a moisture absorbent dielectric material positioned in the dielectric space between the first electrode and the second electrode;at least one inlet enabling moisture from outside the dielectric space to enter the dielectric space and become absorbed by the moisture absorbent material; anda skin electrode and an adhesive layer configured for adhering the skin electrode to a skin portion of a user whereby the skin electrode is capacitively coupled to the skin portion of the user, and wherein the skin electrode is electrically connected to the moisture absorbent material; andwherein the first substrate layer includes an insulating mask that enables the first electrode to be in intimate contact with the moisture absorbent material and the second substrate layer includes an insulating mask that enables the second electrode to be in intimate contact with the moisture absorbent material.
  • 14. The perspiration sensor according to claim 13 wherein the second substrate layer has a predefined thickness that defines a distance between the first electrode and the second electrode.
  • 15. The perspiration sensor according to claim 13 wherein the non-conducting first substrate layer includes an epoxy fiberglass material, the non-conducting second substrate layer includes an epoxy fiberglass material, and the non-conducting third substrate layer includes an epoxy fiberglass material.
  • 16. The perspiration sensor according to claim 13 wherein the non-conducting first substrate layer includes a polyimide material, the non-conducting second substrate layer includes a polyimide material, and the non-conducting third substrate layer includes a polyimide material.
  • 17. The perspiration sensor according to claim 13 wherein the second substrate layer forms a ring that defines the dielectric space.
  • 18. The perspiration sensor according to claim 13 wherein at least one of the first substrate layer and the second substrate layer include an outlet to enable air contained in the dielectric space to escape as moisture enters the dielectric space.
  • 19. The perspiration sensor according to claim 13 further comprising an integrated circuit coupled to the first substrate layer and electrically connected to the first electrode and the second electrode; and wherein the integrated circuit receives a signal from the first electrode and the second electrode and outputs a digital signal as a function of the received signal.
CROSS-REFERENCE TO RELATED APPLICATIONS

This application claims any and all benefits as provided by law including benefit under 35 U.S.C. § 119(e) of the U.S. Provisional Application No. 62/127,124, filed Mar. 2, 1015, the contents of which are incorporated herein by reference in its entirety.

US Referenced Citations (284)
Number Name Date Kind
3716861 Root Feb 1973 A
3805427 Epstein Apr 1974 A
4304235 Kaufman Dec 1981 A
4416288 Freeman Nov 1983 A
4658153 Brosh Apr 1987 A
5272375 Belopolsky Dec 1993 A
5306917 Black Apr 1994 A
5326521 East Jul 1994 A
5331966 Bennett Jul 1994 A
5360987 Shibib Nov 1994 A
5471982 Edwards May 1995 A
5454270 Brown Oct 1995 A
5491651 Janic Feb 1996 A
5567975 Walsh Oct 1996 A
5580794 Allen Dec 1996 A
5617870 Hastings Apr 1997 A
5811790 Endo Sep 1998 A
5817008 Rafert Oct 1998 A
5907477 Tuttle May 1999 A
6042543 Warwick Mar 2000 A
6063046 Allum May 2000 A
6265090 Nishide Jul 2001 B1
6282960 Samuels et al. Sep 2001 B1
6343514 Smith Feb 2002 B1
6387052 Quinn May 2002 B1
6410971 Otey Jun 2002 B1
6421016 Phillips Jul 2002 B1
6450026 Desarnaud Sep 2002 B1
6455931 Hamilton Sep 2002 B1
6567158 Falcial May 2003 B1
6641860 Kaiserman Nov 2003 B1
6775906 Silverbrook Aug 2004 B1
6784844 Boakes Aug 2004 B1
6965160 Cobbley Nov 2005 B2
6987314 Yoshida Jan 2006 B1
7259030 Daniels Aug 2007 B2
7265298 Maghribi Sep 2007 B2
7302751 Hamburgen Dec 2007 B2
7337012 Maghribi Feb 2008 B2
7487587 Vanfleteren Feb 2009 B2
7491892 Wagner Feb 2009 B2
7521292 Rogers Apr 2009 B2
7557367 Rogers Jul 2009 B2
7618260 Daniel Nov 2009 B2
7622367 Nuzzo Nov 2009 B1
7727228 Abboud Jun 2010 B2
7739791 Brandenburg Jun 2010 B2
7759167 Vanfleteren Jul 2010 B2
7960246 Flamand Jun 2011 B2
7982296 Nuzzo Jul 2011 B2
8097926 De Graff Jan 2012 B2
8198621 Rogers Jun 2012 B2
8207473 Axisa Jun 2012 B2
8217381 Rogers Jul 2012 B2
8372726 De Graff Feb 2013 B2
8389862 Arora Mar 2013 B2
8431828 Vanfleteren Apr 2013 B2
8440546 Nuzzo May 2013 B2
8536667 De Graff Sep 2013 B2
8552299 Rogers Oct 2013 B2
8664699 Nuzzo Mar 2014 B2
8679888 Rogers Mar 2014 B2
8729524 Rogers May 2014 B2
8754396 Rogers Jun 2014 B2
8865489 Rogers Oct 2014 B2
8886334 Ghaffari Nov 2014 B2
8905772 Rogers Dec 2014 B2
9012784 Arora Apr 2015 B2
9082025 Fastert Jul 2015 B2
9105555 Rogers Aug 2015 B2
9105782 Rogers Aug 2015 B2
9119533 Ghaffari Sep 2015 B2
9123614 Graff Sep 2015 B2
9159635 Elolampi Oct 2015 B2
9168094 Lee Oct 2015 B2
9171794 Rafferty Oct 2015 B2
9186060 De Graff Nov 2015 B2
9226402 Hsu Dec 2015 B2
9247637 Hsu Jan 2016 B2
20010012918 Swanson Aug 2001 A1
20010021867 Kordis Sep 2001 A1
20020000081 Hirono et al. Jan 2002 A1
20020026127 Balbierz Feb 2002 A1
20020082515 Campbell Jun 2002 A1
20020094701 Biegelsen Jul 2002 A1
20020113739 Howard Aug 2002 A1
20020128700 Cross, Jr. Sep 2002 A1
20020145467 Minch Oct 2002 A1
20020151934 Levine Oct 2002 A1
20020158330 Moon Oct 2002 A1
20030017848 Engstrom Jan 2003 A1
20030045025 Coyle Mar 2003 A1
20030097165 Krulevitch May 2003 A1
20030120271 Burnside Jun 2003 A1
20030162507 Vatt Aug 2003 A1
20030214408 Grajales Nov 2003 A1
20030236455 Swanson Dec 2003 A1
20040006264 Mojarradi Jan 2004 A1
20040085469 Johnson May 2004 A1
20040092806 Sagon May 2004 A1
20040106334 Suzuki Jun 2004 A1
20040135094 Niigaki Jul 2004 A1
20040138558 Dunki-Jacobs Jul 2004 A1
20040149921 Smyk Aug 2004 A1
20040178466 Merrill Sep 2004 A1
20040192082 Wagner Sep 2004 A1
20040201134 Kawai Oct 2004 A1
20040203486 Shepherd Oct 2004 A1
20040221370 Hannula Nov 2004 A1
20040243204 Maghribi Dec 2004 A1
20050021103 DiLorenzo Jan 2005 A1
20050029680 Jung Feb 2005 A1
20050067293 Naito Mar 2005 A1
20050070778 Lackey Mar 2005 A1
20050096513 Ozguz May 2005 A1
20050113744 Donoghue May 2005 A1
20050139683 Yi Jun 2005 A1
20050171524 Stern Aug 2005 A1
20050203366 Donoghue Sep 2005 A1
20060003709 Wood Jan 2006 A1
20060038182 Rogers Feb 2006 A1
20060071349 Tokushige Apr 2006 A1
20060084394 Engstrom Apr 2006 A1
20060106321 Lewinsky May 2006 A1
20060128346 Yasui Jun 2006 A1
20060154398 Qing Jul 2006 A1
20060160560 Josenhans Jul 2006 A1
20060248946 Howell Nov 2006 A1
20060257945 Masters Nov 2006 A1
20060264767 Shennib Nov 2006 A1
20060270135 Chrysler Nov 2006 A1
20060286785 Rogers Dec 2006 A1
20070027514 Gerber Feb 2007 A1
20070031283 Davis Feb 2007 A1
20070108389 Makela May 2007 A1
20070113399 Kumar May 2007 A1
20070123756 Kitajima May 2007 A1
20070019088 Dubrow et al. Aug 2007 A1
20070270672 Hayter Nov 2007 A1
20070270674 Kane et al. Nov 2007 A1
20080036097 Ito Feb 2008 A1
20080046080 Vanden Bulcke Feb 2008 A1
20080074383 Dean Mar 2008 A1
20080096620 Lee Apr 2008 A1
20080139894 Szydlo-Moore Jun 2008 A1
20080157235 Rogers Jul 2008 A1
20080188912 Stone Aug 2008 A1
20080193749 Thompson Aug 2008 A1
20080204021 Leussler Aug 2008 A1
20080211087 Mueller-Hipper Sep 2008 A1
20080237840 Alcoe Oct 2008 A1
20080259576 Johnson Oct 2008 A1
20080287167 Caine Nov 2008 A1
20080313552 Buehler Dec 2008 A1
20090000377 Shipps Jan 2009 A1
20090001550 Yonggang Jan 2009 A1
20090015560 Robinson Jan 2009 A1
20090017884 Rotschild Jan 2009 A1
20090048556 Durand Feb 2009 A1
20090088750 Hushka Apr 2009 A1
20090107704 Vanfleteren Apr 2009 A1
20090154736 Lee Jun 2009 A1
20090184254 Miura Jul 2009 A1
20090204168 Kallmeyer Aug 2009 A1
20090215385 Waters Aug 2009 A1
20090225751 Koenck Sep 2009 A1
20090261828 Nordmeyer-Massner Oct 2009 A1
20090273909 Shin Nov 2009 A1
20090283891 Dekker Nov 2009 A1
20090291508 Babu Nov 2009 A1
20090294803 Nuzzo Dec 2009 A1
20090322480 Benedict Dec 2009 A1
20100002402 Rogers Jan 2010 A1
20100030167 Thirstrup et al. Feb 2010 A1
20100059863 Rogers Mar 2010 A1
20100072577 Nuzzo Mar 2010 A1
20100073669 Colvin Mar 2010 A1
20100087782 Ghaffari Apr 2010 A1
20100090781 Yamamoto Apr 2010 A1
20100090824 Rowell Apr 2010 A1
20100116526 Arora May 2010 A1
20100117660 Douglas May 2010 A1
20100178722 De Graff Jul 2010 A1
20100245011 Chatzopoulos Sep 2010 A1
20100271191 De Graff Oct 2010 A1
20100298895 Ghaffari Nov 2010 A1
20100317132 Rogers Dec 2010 A1
20100321161 Isabell Dec 2010 A1
20100327387 Kasai Dec 2010 A1
20110011179 Gustafsson Jan 2011 A1
20110034912 De Graff Feb 2011 A1
20110051384 Kriechbaum Mar 2011 A1
20110054583 Litt Mar 2011 A1
20110101789 Salter May 2011 A1
20110121822 Parsche May 2011 A1
20110140897 Purks Jun 2011 A1
20110175735 Forster Jul 2011 A1
20110184320 Shipps Jul 2011 A1
20110215931 Callsen Sep 2011 A1
20110218756 Callsen Sep 2011 A1
20110218757 Callsen Sep 2011 A1
20110220890 Nuzzo Sep 2011 A1
20110277813 Rogers Nov 2011 A1
20110284268 Palaniswamy Nov 2011 A1
20110306851 Wang Dec 2011 A1
20120016258 Webster Jan 2012 A1
20120051005 Vanfleteren Mar 2012 A1
20120052268 Axisa Mar 2012 A1
20120065937 De Graff Mar 2012 A1
20120074546 Chong Mar 2012 A1
20120087216 Keung Apr 2012 A1
20120091594 Landesberger Apr 2012 A1
20120092178 Callsen Apr 2012 A1
20120092222 Kato Apr 2012 A1
20120101413 Beetel Apr 2012 A1
20120101538 Ballakur Apr 2012 A1
20120108012 Yasuda May 2012 A1
20120126418 Feng May 2012 A1
20120015007 Revol-Cavalier et al. Jun 2012 A1
20120157804 Rogers Jun 2012 A1
20120172697 Urman Jul 2012 A1
20120226130 De Graff Sep 2012 A1
20120244848 Ghaffari Sep 2012 A1
20120256308 Helin Oct 2012 A1
20120316455 Rahman Dec 2012 A1
20120327608 Rogers Dec 2012 A1
20130041235 Rogers Feb 2013 A1
20130099358 Elolampi Apr 2013 A1
20130100618 Rogers Apr 2013 A1
20130012358 Sarrafzadeh et al. May 2013 A1
20130118255 Callsen May 2013 A1
20130150693 D'angelo Jun 2013 A1
20130185003 Carbeck Jul 2013 A1
20130019731 Monty et al. Aug 2013 A1
20130192356 De Graff Aug 2013 A1
20130200268 Rafferty Aug 2013 A1
20130211761 Brandsma Aug 2013 A1
20130214300 Lerman Aug 2013 A1
20130215467 Fein Aug 2013 A1
20130225965 Ghaffari Aug 2013 A1
20130237150 Royston Sep 2013 A1
20130245388 Rafferty Sep 2013 A1
20130274562 Ghaffari Oct 2013 A1
20130313713 Arora Nov 2013 A1
20130316442 Meurville Nov 2013 A1
20130316487 De Graff Nov 2013 A1
20130320503 Nuzzo Dec 2013 A1
20130321373 Yoshizumi Dec 2013 A1
20140001058 Ghaffari Jan 2014 A1
20140012160 Ghaffari Jan 2014 A1
20140012242 Lee Jan 2014 A1
20140022746 Hsu Jan 2014 A1
20140039290 De Graff Feb 2014 A1
20140097944 Fastert Apr 2014 A1
20140110859 Rafferty Apr 2014 A1
20140140020 Rogers May 2014 A1
20140188426 Fastert Jul 2014 A1
20140191236 Nuzzo Jul 2014 A1
20140216524 Rogers Aug 2014 A1
20140240932 Hsu Aug 2014 A1
20140249520 Ghaffari Sep 2014 A1
20140303452 Ghaffari Oct 2014 A1
20140340857 Hsu Nov 2014 A1
20140374872 Rogers Dec 2014 A1
20140375465 Fenuccio Dec 2014 A1
20150001462 Rogers Jan 2015 A1
20150019135 Kacyvenski Jan 2015 A1
20150035680 Li Feb 2015 A1
20150069617 Arora Mar 2015 A1
20150099954 Achmann Apr 2015 A1
20150099976 Ghaffari Apr 2015 A1
20150100135 Ives Apr 2015 A1
20150194817 Lee Jul 2015 A1
20150237711 Rogers Aug 2015 A1
20150241288 Keen Aug 2015 A1
20150260713 Ghaffari Sep 2015 A1
20150272652 Ghaffari Oct 2015 A1
20150286913 Fastert Oct 2015 A1
20150320472 Ghaffari Nov 2015 A1
20150335254 Elolampi Nov 2015 A1
20150342036 Fastert Nov 2015 A1
20160027834 de Graff Jan 2016 A1
20160045162 De Graff Feb 2016 A1
20160081192 Hsu Mar 2016 A1
Foreign Referenced Citations (60)
Number Date Country
102007046886 Apr 2009 DE
0585670 Mar 1994 EP
0779059 Jun 1997 EP
1808124 Jul 2007 EP
2259062 Dec 2010 EP
05-087511 Apr 1993 JP
2009-170173 Jul 2009 JP
WO 1999038211 Jul 1999 WO
WO 2005122285 Dec 2005 WO
WO 2003021679 Mar 2006 WO
WO 2007003019 Jan 2007 WO
WO 2007024983 Mar 2007 WO
WO 2007116344 Oct 2007 WO
WO 2007136726 Nov 2007 WO
WO 2008030960 Mar 2008 WO
WO 2009111641 Sep 2009 WO
WO 2009114689 Sep 2009 WO
WO 2010036807 Apr 2010 WO
WO 2010042653 Apr 2010 WO
WO 2010042957 Apr 2010 WO
WO 2010046883 Apr 2010 WO
WO 2010056857 May 2010 WO
WO 2010081137 Jul 2010 WO
WO 2010082993 Jul 2010 WO
WO 2010102310 Sep 2010 WO
WO 2010132552 Nov 2010 WO
WO 2011003181 Jan 2011 WO
WO 2011041727 Apr 2011 WO
WO 2011084450 Jul 2011 WO
WO 2011084709 Jul 2011 WO
WO 2011127331 Oct 2011 WO
WO 2012125494 Sep 2012 WO
WO 2012166686 Dec 2012 WO
WO 2013010171 Jan 2013 WO
WO 2013022853 Feb 2013 WO
WO 2013033724 Mar 2013 WO
WO 2013034987 Mar 2013 WO
WO 2013049716 Apr 2013 WO
WO 2013052919 Apr 2013 WO
WO 2013170032 Nov 2013 WO
WO 2014007871 Jan 2014 WO
WO 2014058473 Apr 2014 WO
WO 2014059032 Apr 2014 WO
WO 2014106041 Jul 2014 WO
WO 2014110176 Jul 2014 WO
WO 2014130928 Aug 2014 WO
WO 2014130931 Aug 2014 WO
WO 2014186467 Nov 2014 WO
WO 2014197443 Dec 2014 WO
WO 2014205434 Dec 2014 WO
WO 2015021039 Feb 2015 WO
WO 2015054312 Apr 2015 WO
WO 2015077559 May 2015 WO
WO 2015080991 Jun 2015 WO
WO 2015102951 Jul 2015 WO
WO 2015103483 Jul 2015 WO
WO 2015103580 Jul 2015 WO
WO 2015127458 Aug 2015 WO
WO 2015134588 Sep 2015 WO
WO 2015138712 Sep 2015 WO
Non-Patent Literature Citations (17)
Entry
Carvalhal et al., “Electrochemical Detection in a Paper-Based Separation Device”, Analytical Chemistry, vol. 82, No. 3, (1162-1165) (4 pages) (Jan. 7, 2010).
Demura et al., “Immobilization of Glucose Oxidase with Bombyx mori Silk Fibroin by Only Stretching Treatment and its Application to Glucose Sensor,” Biotechnology and Bioengineering, vol. 33, 598-603 (6 pages) (1989).
Ellerbee et al., “Quantifying Colorimetric Assays in Paper-Based Microfluidic Devices by Measuring the Transmission of Light through Paper,” Analytical Chemistry, vol. 81, No. 20 8447-8452, (6 pages) (Oct. 15, 2009).
Halsted, “Ligature and Suture Material,” Journal of the American Medical Association, vol. LX, No. 15, 1119-1126, (8 pages) (Apr. 12, 1913).
Kim et al., “Complementary Metal Oxide Silicon Integrated Circuits Incorporating Monolithically Integrated Stretchable Wavy Interconnects,” Applied Physics Letters, vol. 93, 044102-044102.3 (3 pages) (Jul. 31, 2008).
Kim et al., “Dissolvable Films of Silk Fibroin for Ultrathin Conformal Bio-Integrated Electronics,” Nature, 1-8 (8 pages) (Apr. 18, 2010).
Kim et al., “Materials and Noncoplanar Mesh Designs for Integrated Circuits with Linear Elastic Responses to Extreme Mechanical Deformations,” PNAS, vol. 105, No. 48, 18675-18680 (6 pages) (Dec. 2, 2008).
Kim et al., “Stretchable and Foldable Silicon Integrated Circuits,” Science, vol. 320, 507-511 (5 pages) (Apr. 25, 2008).
Kim et al., “Electrowetting on Paper for Electronic Paper Display,” ACS Applied Materials & Interfaces, vol. 2, No. 11, (3318-3323) (6 pages) (Nov. 24, 2010).
Ko et al., “A Hemispherical Electronic Eye Camera Based on Compressible Silicon Optoelectronics,” Nature, vol. 454, 748-753 (6 pages) (Aug. 7, 2008).
Lawrence et al., “Bioactive Silk Protein Biomaterial Systems for Optical Devices,” Biomacromolecules, vol. 9, 1214-1220 (7 pages) (Nov. 4, 2008).
Meitl et al., “Transfer Printing by Kinetic Control of Adhesion to an Elastomeric Stamp,” Nature, vol. 5, 33-38 (6 pages) (Jan. 2006).
Omenetto et al., “A New Route for Silk,” Nature Photonics, vol. 2, 641-643 (3 pages) (Nov. 2008).
Omenetto et al., “New Opportunities for an Ancient Material,” Science, vol. 329, 528-531 (5 pages) (Jul. 30, 2010).
Siegel et al., “Foldable Printed Circuit Boards on Paper Substrates,” Advanced Functional Materials, vol. 20, No. 1, 28-35, (8 pages) (Jan. 8, 2010).
Tsukada et al., “Structural Changes of Silk Fibroin Membranes Induced by Immersion in Methanol Aqueous Solutions,” Journal of Polymer Science, vol. 32, 961-968 (8 pages) (1994).
Wang et al., “Controlled Release From Multilayer Silk Biomaterial Coatings to Modulate Vascular Cell Responses” Biomaterials, 29, 894-903 (10 pages) (Nov. 28, 2008).
Related Publications (1)
Number Date Country
20160256070 A1 Sep 2016 US
Provisional Applications (1)
Number Date Country
62127124 Mar 2015 US