Claims
- 1. A pharmaceutical composition for local external cutaneous treatment of a local subcutaneous edema of a human, the composition comprising a suspension for skin use consisting of the following:
- 10 parts of acetazolamide (5-acetamido-1,3,4-thiadiazole-2-sulfonamide),
- 10 parts of polyethylene glycol 300,
- 5 parts of stearic acid,
- 3.5 parts of liquid petrolatum,
- 3 parts of ascorbyl palmitate and
- 100 parts of water q.s.p.
- 2. A skin cream for local external cutaneous treatment of a local subcutaneous edema of a human, the skin cream comprising:
- 10 parts of acetazolamide (5-acetamido-1,3,4-thiadiazole-2-sulfonamide),
- 10 parts of poly-oxy-ethylene glycerides,
- 10 parts of polyethylene glycol stearate 300,
- 0.07 parts of methyl para-hydroxybenzoate,
- 0.04 parts of propyl para-hydroxybenzoate and
- 100 parts of water q.s.p.
- 3. A method for cutaneous local treatment of a local subcutaneous edema of a human which method comprises applying to the skin over the edema a pharmaceutical composition which comprises:
- a pharmaceutical carrier compatible with cutaneous external application,
- a diuretic agent capable of passing the epidermal barrier incorporated in the pharmaceutical carrier; said agent being acetazolamide (5-acetamido-1,3,4-thiadiazole -2-sulfonamide), with a range of concentration being between 1% and 50% by weight.
- 4. A method for cutaneous local treatment of a local subcutaneous edema of a human which method comprises applying to the skin over the edema a pharmaceutical composition which comprises:
- an emulsified pharmaceutical carrier compatible with cutaneous external application,
- a diuretic agent capable of passing the epidermal barrier incorporated in the pharmaceutical carrier; said agent being acetazolamide (5-acetamido-1,3,4,-thiadiazole-2-sulfonamide), with a range of concentration being between 1 and 50% by weight.
CROSS REFERENCE
This is a continuation-in-part application with respect to our copending United States Patent Application 146,298 filed May 24, 1971, now U.S. Pat. No. 3,934,016.
Non-Patent Literature Citations (1)
Entry |
remingtons Pharmaceutical Sciences, 13th Ed. (1965), pp. 884, 1016-1017, 1240, 1424-1426. |
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
146298 |
May 1971 |
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