Claims
- 1. A 2-omega-aminoalkoxydiphenyl sulfide compound having the formula: ##STR7## wherein n 3-5 and when n = 3, R is C.sub.1 -C.sub.5 alkylamino; when n = 4, R is amino, C.sub.1 -C.sub.5 alkylamino, C.sub.2 -C.sub.6 dialkylamino or morpholino; and when n = 5, R is C.sub.2 -C.sub.6 dialkylamino or morpholino, and acid addition salts thereof.
- 2. The compound of claim 1 wherein R is selected from the group consisting of amino, methylamino, dimethylamino and morpholino.
- 3. The compound of claim 1 which is 2-(3-methylaminopropoxy)-diphenyl sulfide.
- 4. The compound of claim 1 which is 2-(4-methylaminobutoxy)-diphenyl sulfide.
- 5. The compound of claim 1 which is 2-(4-dimethylaminobutoxy)-diphenyl sulfide.
- 6. The compound of claim 1 which is 2-(4-aminobutoxy) diphenyl sulfide.
- 7. The compound of claim 1 which is 2-(4-morpholinobutoxy)-diphenyl sulfide.
- 8. The compound of claim 1 which is 2-(5-dimethylaminopentyloxy)-diphenyl sulfide.
- 9. A compound of claim 1 selected from the group consisting of 2-(3-methylaminopropoxy)-diphenyl sulfide, 2-(4-methylaminobutoxy)-diphenyl sulfide and 2-(4-dimethylaminobutoxy)-diphenyl sulfide.
- 10. A compound of claim 1 selected from the group consisting of 2-(3-methylaminopropoxy)-diphenyl sulfide, 2-(4-methylaminobutoxy)-diphenyl sulfide, 2-(4-dimethylaminobutoxy)-diphenyl sulfide, 2-(4-aminobutoxy) diphenyl sulfide and 2-(4-morpholinobutoxy)-diphenyl sulfide.
- 11. The compound of claim 1 wherein R is amino, C.sub.1 -C.sub.5 alkylamino or C.sub.2 -C.sub.6 dialkylamino.
- 12. An antidepressant composition which comprises an antidepressant effective amount of a compound of claim 1 and a pharmaceutically acceptable adjuvant.
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a continuation-in-part of U.S. application Ser. No. 627,059, filed Oct. 30, 1975 and now abandoned.
Non-Patent Literature Citations (3)
Entry |
toyoshima et al. (I) "Chemical Abstracts", vol. 72, p. 282 Section 3152y (1970). |
Toyoshima et al. (II), "J. Pharm. Soc. Japan," vol. 89, pp. 1417-1425 (1970). |
Protiva et al., "Chemical Abstracts", vol. 45, p. 577 (1951). |
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
627059 |
Oct 1975 |
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