Claims
- 1. A method for lowering an elevated cholesterol or lipid level in a human adult, which comprises
- orally administering thereto an effective cholesterol or lipid lowering amount of a phenoxyaliphatic carboxylic acid derivative of the formula ##SPC31##
- wherein D and E each are hydrogen; and
- R.sup.1 and R.sup.2 each are methyl, or R.sup.1 and R.sup.2 may form cyclohexylidene together with a carbon atom bonded therewith;
- R.sup.3 is methyl;
- R.sup.4 is methyl, ethyl or n-propyl; and
- Y is hydroxyl or ethoxy, provided that Y is hydroxyl when R.sup.1 and R.sup.2 form cyclohexylidene together with a carbon atom bonded therewith and R.sup.4 is methyl or n-propyl, and Y is ethoxy when R.sup.1 and R.sup.2 each are methyl and R.sup.4 is ethyl.
- 2. The method according to claim 1, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC32##
- 3. The method according to claim 1, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC33##
- 4. The method according to claim 1, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC34##
- 5. The method according to claim 1, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC35##
- 6. The method according to claim 1, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC36##
- 7. The method according to claim 1, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC37##
- 8. The method according to claim 1, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC38##
- 9. A pharmaceutical composition consisting of an elevated cholesterol or lipid level lowering effective amount of a phenoxyaliphatic carboxylic acid derivative of the formula ##SPC39##
- wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, Y, D and E are defined in claim 1, and a suitable carrier.
- 10. The pharmaceutical composition according to claim 9, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC40##
- 11. The pharmaceutical composition according to claim 9, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC41##
- 12. The pharmaceutical composition according to claim 9, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC42##
- 13. The pharmaceutical composition according to claim 9, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC43##
- 14. The pharmaceutical composition according to claim 9, wherein said phenoxyaliphatic carboxylic acid derivative is represented the formula, ##SPC44##
- 15. The pharmaceutical composition according to claim 9, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC45##
- 16. The pharmaceutical composition according to claim 9, wherein said phenoxyaliphatic carboxylic acid derivative is of the formula, ##SPC46##
Priority Claims (8)
Number |
Date |
Country |
Kind |
44-29905 |
Apr 1969 |
JA |
|
44-29907 |
Apr 1969 |
JA |
|
44-34166 |
May 1969 |
JA |
|
44-34167 |
May 1969 |
JA |
|
44-80041 |
Oct 1969 |
JA |
|
44-80042 |
Oct 1969 |
JA |
|
45-102809 |
Dec 1969 |
JA |
|
45-104194 |
Dec 1969 |
JA |
|
Parent Case Info
This application is a division of application Ser. No. 206,966, filed Dec. 10, 1971, now U.S. Pat. No. 3,821,404, which is a division of application Ser. No. 26,412 filed Apr. 7, 1970, now U.S. Pat. No. 3,716,583.
US Referenced Citations (7)
Divisions (2)
|
Number |
Date |
Country |
Parent |
206966 |
Dec 1971 |
|
Parent |
26412 |
Apr 1970 |
|