The present invention relates to a photon counting detector, a corresponding photon counting method and an imaging apparatus comprising a photon counting detector for detection of radiation, in particular gamma radiation and x-ray radiation.
Photon counting has conventionally been implemented using photomultiplier tube (PMT) detectors, which comprise a light-sensitive photocathode and a set of “multiplier” anode terminals. The photocathode emits at least one electron responsive to impingement of a photon, and the electron(s) in turn strike successive anode terminals with each such event causing emission of a cascade of electrons, thus producing a multiplication effect that results in a measurable electrical pulse. A PMT is capable of high-speed photon counting. PMT detectors have disadvantages including being relatively bulky discrete devices with large optical windows that operate at high voltage and are susceptible to failure due to the evacuated tube design and the high operational electrical voltage. A radiation detector of this kind is e.g. disclosed in U.S. Pat. No. 8,723,132 B2.
Silicon photomultiplier (SiPM) devices have been developed to overcome some of these disadvantages, and to provide photon-counting detectors that are readily integrated with silicon-based signal/data processing circuitry. In some embodiments, a SiPM device employs an avalanche photodiode as the light sensor. When biased above its breakdown voltage, the avalanche diode goes into breakdown responsive to impingement of a single photon. Such a device is sometimes called a single photon avalanche diode (SPAD) detector. In a typical SPAD detector, the avalanche photodiode is reverse biased above its breakdown voltage and is in series with a quenching resistor. Impingement of a single photon causes the p-n junction to break down in a multiplicative (i.e., “avalanche”) cascade of charge carriers that flow in the SPAD detector as a measurable electrical current. This current is quenched relatively quickly as voltage over the resistor due to the current flow lowers the reverse bias across the avalanche diode to a level below its break down voltage. Additionally or alternatively, an active quenching sub-circuit comprising (for example) one or more diodes, resistors, and/or transistors can provide more rapid quenching. Some illustrative examples of SiPM detector arrays are disclosed U.S. Pat. Nos. 9,268,033 B2 and 10,078,141 B2.
WO 2010/100574 A2 discloses a PET scanner including a ring of detector modules encircling an imaging region. Each of the detector modules includes one or more sensor avalanche photodiodes (APDs) that are biased in a breakdown region in a Geiger mode. The sensor APDs output pulses in response to light from a scintillator corresponding to incident photons. A reference APD also biased in a breakdown region in a Geiger mode is optically shielded from light and outputs a voltage that is measured by an analog to digital converter. Based on the measurement, a bias control feedback loop directs a variable voltage generator to adjust a bias voltage applied to the APDs such that a difference between a voltage of a breakdown pulse and a preselected logic voltage level is minimized.
Further prior art can be found in US 2018/292550 A1, WO 2014/184714 A1 and U.S. Pat. No. 9,954,124 B1.
Digital silicon photomultipliers are used as photon counting detectors (sometimes also called photon detectors) in high-performance PET/CT systems. Coupled to a time-of-flight capable scintillator, the fast trigger logic of the digital silicon photomultiplier enables time resolution in the range of 100 ps-200 ps. Time resolution of these systems is limited, among others, by the time spread of the scintillation process. New detector concepts using prompt photons have been proposed, potentially offering improvement of time resolution significantly below 100 ps.
Strong radiation fields irradiating an image sensor (e.g. a CMOS image sensor) can cause damage to the device, leading to higher leakage, dark noise and change in the spectral sensitivity. In case of SPADs exposed to flux of radiation photons, the effect is a temporary (undesired) increase of the dark count rate.
It is an object of the present invention to mitigate potential negative effects of x-ray or gamma irradiation in SPAD-based photon counting detectors used e.g. in photon counting spectral CT applications.
In a first aspect of the present invention a photon counting detector is presented comprising:
In a further aspect of the present invention a corresponding photon counting method is presented.
In a still further aspect of the present invention an imaging apparatus comprising a photon counting detector as disclosed herein is presented.
Preferred embodiments of the invention are defined in the dependent claims.
The present invention is based on the idea to locally increase the temperature of the SPAD and its surroundings in order to speed up the damage repair due to x-ray or gamma irradiation. Rather than using additional structural elements or hardware, like additional heating elements or heating wires embedded into the detector, the SPAD itself is configured and used as heating element. A SPAD biased constantly above its breakdown voltage will eventually break down and start conducting current. This breakdown is typically stopped by a quenching resistor (in passively quenched SPADs) or through activation of an active quench and recharge circuit (in actively quenched SPADs). According to the present invention the current flow is continued for a certain time (also called “heating period” herein) to heat the SPAD and thus enable damage repair and reduction of the dark count rate (DCR). This solution does not require any modification of existing hardware, particularly for actively quenched SPADs.
According to an embodiment the circuitry is configured to control the length of the heating period based on the amount of dark count rate and/or the extent by which the dark count rate exceeded the dark count rate threshold. In particular, the length of the heating period is controlled to be longer the larger the amount of dark count rate is and/or the higher the extent is by which the dark count rate exceeded the dark count rate threshold.
One or more predetermined lengths may be defined in advance (and e.g. stored in a look-up table or stored in a memory accessible by the circuitry), for which a length is selected, e.g. based on the amount of dark count rate and/or the extent by which the dark count rate exceeded the dark count rate threshold. Hence, the length of the heating period can be made programmable, enabling a simple and quick control of the heating period.
The detector may further comprise circuitry configured to measure the dark count rate of the SPAD. The measurement may be carried out in advance to determine if and by which amount a reduction of the dark count rate is needed or desired. The dark count rate may also be measured after a damage repair to check the success of the damage repair.
In another embodiment the circuitry is configured to ramp up the reverse bias voltage until a bias current caused by application of the reverse bias voltage to flow reaches a bias current limit.
The circuitry may further be configured to ramp down the reverse bias voltage below breakdown voltage after the heating period and to recharge the SPAD to become sensitive for optical photon detection. This brings the SPAD back to normal operation mode.
In an embodiment the SPAD is insensitive for optical photon detection during the heating period. This avoids that any additional heat during the damage repair may cause a further increase of the dark noise of the SPAD. It is intended to disable high-DCR SPADs in normal operation to reduce the overall noise, and in case of the damage repair, it is re-used to select only SPADs that show a certain level of damage (and to limit the requirements on the SPAD current supply). The SPAD may be insensitive for optical photon detection during the heating period because it is forced into breakdown, in particular into DC breakdown. In this context DC means there is a constant avalanche current going through the SPAD for the time of the damage repair which heats the SPAD internally because of the inner resistance of the SPAD. Thus, due to the physics of the SPAD, and by forcing the SPAD into breakdown and avoiding that the breakdown is stopped by a quenching resistor or through activation of an active quench and recharge circuit, the SPAD may be made insensitive.
The circuitry may be configured to monitor the temperature of the SPAD during the heating period by measuring the reverse bias voltage level, in particular while keeping the bias current level constant. In this way, overheating can be avoided and the intensity and speed of damage repair can be controlled. Hereby, the circuitry may be configured to control the reverse bias voltage level during the heating level not to fall below a level required to maintain constant current through the SPAD.
Typically, it is desired to heat the SPAD up to certain temperature and keep it there for certain time. However, when the SPAD temperature changes, the ionization rates in the SPAD junction change as well and that determines the current. The current should be above a certain level, e.g. above 20 μA, in order to start a self-sustained avalanche. The way to compensate for the temperature-dependence of the ionization rates is to modulate the bias voltage so that the current stays constant in order to deposit a certain amount of heat energy into the SPAD. The temperature dependence of the ionization coefficients manifests itself in temperature dependency of the breakdown voltages, which increases by approximately 20 mV/K (process-dependent). As this is generally known for the detector, the SPAD temperature can be estimated by looking at the drift of the bias voltage during heating.
The claimed imaging apparatus that comprises a photon counting detector as disclosed herein may e.g. be a PET apparatus, a CT apparatus, a SPECT apparatus, a Time-of-Flight (TOF) PET apparatus, or a Compton camera.
These and other aspects of the invention will be apparent from and elucidated with reference to the embodiment(s) described hereinafter. In the following drawings
In a comparison unit 13 the number X of detected photons (or a sum of several samples) is compared to a fixed threshold A. If the value X exceeds A, an event is detected and a finite state machine 14 starts an acquisition by accumulating a predefined number of samples in an energy accumulator 15. At the end of the acquisition, the accumulator value is stored in an x-ray energy register 16 and the accumulator 15 is reset in preparation for the next event. The value stored in the energy register 16 is then sorted in an energy histogram 17, where the corresponding bin is increased.
The scintillator 20 may be selected to provide high stopping power for gamma rays or x-rays with rapid temporal decay of the scintillation burst. Some suitable scintillator materials are LSO, LYSO, MLS, LGSO, LaBr, LuAP/LuAG, GAGG and mixtures thereof. It should be appreciated that other scintillator materials can also be used. Although
Single-photon avalanche diodes are devices capable of detecting single photons. One of the non-ideal properties of these sensitive devices is the presence of dark counts-detections unrelated to a photon-appearing as a random noise of the detector. This random noise adds to the detected signal and reduces its quality, and by this means the quality of the final result. One reason for the dark count noise is the presence of defects and impurities in the sensitive volume of the SPAD, leading to thermal generation of carriers by the Shockley-Reed-Hall process. This component of the dark count noise is related to the manufacturing of the device (purity of the materials and annealing steps in the semiconductor line).
Another component of the dark count noise can originate from the SPAD guard ring. SPAD guard ring is the volume surrounding the high field region of the SPAD. Its purpose is to provide a smooth transition of the high-field to low-field area without the presence of field spikes, which would lead to premature breakdown (edge or corner breakdown) of the device. In a working SPAD, the guard ring is designed to not affect the performance of the SPAD, meaning its width is sufficient to suppress the edge breakdown but not too wide as to adversely affect the fill factor of the SPAD, as the region of the guard ring is not sensitive to photons. Often, the guard ring is realized as “virtual guard ring”
The sensitive area of the SPAD exhibits the highest field strength of the electric field magnitude while the field taper off in the guard ring region towards a shallow and deep trench isolation. These isolation trenches typically consist of silicon dioxide, and deep trenches can additionally be filled with polycrystalline silicon.
Normally, these isolation trench materials are neutral, as are the backend of line (BEOL) oxide layers on top of the SPAD. Irradiation with high-energetic photons (x-rays, gamma photons) can create trapped charge buildup inside these isolation layers. This charge can modify the field distribution inside the guard ring and can lead to a substantial increase of the dark count rate of the SPAD due to premature breakdown of the guard ring. This is illustrated in
From
One of the main elements of the present invention is a means to locally increase the temperature of the SPAD and its surroundings in order to speed up the damage repair due to the irradiation with x-ray or gamma radiation. Instead of providing one or more additional hardware elements, such as a heating wire or another heating element, according to the present invention the SPAD itself is configured as a heating element, thereby eliminating the need for additional hardware. As explained above, a SPAD biased constantly above its breakdown voltage, e.g. through a low-ohmic path, will eventually break down and start conducting current. In contrast, the SPAD is normally biased above breakdown either through a resistor (limiting current to e.g. less than 20 μA so it is several 100 kOhm) or charged up by a short pulse to a recharge switch that is then open so that the SPAD is not connected.
In addition to the detector cell 50 shown in
The circuitry 82 may be provided by a measurement signal from the system, e.g. from the counter/FIFO buffer 66, that indicates the dark count rate of the SPAD. The counter/FiFO buffer 66 may thus be configured to measure the dark count rate of the SPAD. The measurement may thus be done on SPAD level, but in another implementation this function would be located to a next level, e.g. an FPGA or other processing circuitry, and the detector would only provide means to externally control the state of the recharge FET, as shown in
The measurement may be carried out in advance to determine if and by which amount a reduction of the dark count rate is needed or desired. The dark count rate may also be measured after a damage repair to check the success of the damage repair.
A flow chart of an embodiment of a method 100 according to the present invention for use in a detector having actively quenched SPADs, assuming full control over the quench and recharge switch configuration, is shown in
Generally, each SPAD can be individually controlled for damage repair at an individual timing. However, since the SPAD is inoperative during the damage repair, it is preferred that all SPADs or the SPADs that require damage repair are controlled for damage repair at the same time. The damage repair may occur occasionally (e.g. on demand or at regular intervals) and when the imaging apparatus (e.g. a CT scanner) is not in use.
Dark count rate measurement is preferably carried out prior and, optionally, after the repair in order to justify the need and prove the success of the measure. The current in the order of a few mA to a few 100 mA can be adjusted in step S3, thereby locally increasing the SPAD temperature. As the SPAD is in close proximity to the damaged area, the heating will help restore the operation of the guard ring.
When carrying out this operation, the current shall be closely monitored and the SPAD interconnect may be designed in such a way as to minimize potential ageing issues due to electromigration. The SPAD current should be as low as necessary and the time as short as possible.
A flow chart of another embodiment of a method 200 according to the present invention is shown in
For the treatment of a SPAD, the method as shown in
Power dissipated inside the SPAD junction will lead to a local increase of the SPAD temperature (step S17). As the temperature coefficient of the SPAD is generally well known (in the range of 20 mV/K), change of the bias voltage Vbias (assuming the bias power supply is configured to provide a constant bias current) can be used to determine the junction temperature (here neglecting change of the resistance by heating-up of the interconnect). Higher temperature accelerates the reduction of radiation damage in the SPAD.
Finally, it is checked (step S18) if all SPADs have been treated. If yes, it is waited (step S19) until the sensor sufficiently cools down before the method proceeds with step 11 (or waits for a new iteration of damage repair is started). If not all SPADs have been treated yet, the method proceeds with step S14 to treat one or more further SPADs.
During normal operation (indicated in
The SPAD voltage Vspad (the bias voltage) ramps up from the breakdown voltage Vbreakdown to a higher voltage Vbreakdown+Vexcess. The SPAD is now sensitive to single photos. A photon arriving at the SPAD (an event) leads a short increase of the current Ispad through the SPAD above the quiescent current Iquiescent and a breakdown so that the SPAD voltage Vspad breaks down and decreases back to (or even below) the breakdown voltage Vbreakdown. Afterwards, the SPAD is recharged again to make it sensitive for photon arrival.
During damage repair (damage anneal) operation (indicated in
In summary, according to the present invention current flow through the SPAD itself is provided, e.g. by suitable configuration of the active quench and recharge circuit and DC current through the device. This solution requires no (or at least no substantial) modification of existing hardware, in particular as long as the recharge switch can be controlled externally. It achieves damage repair of the respective SPAD and thus mitigates potential negative effects of x-ray or gamma irradiation in SPAD-based photon counting detectors, such as higher leakage, higher dark noise and change in spectral sensitivity.
While the invention has been illustrated and described in detail in the drawings and foregoing description, such illustration and description are to be considered illustrative or exemplary and not restrictive; the invention is not limited to the disclosed embodiments. Other variations to the disclosed embodiments can be understood and effected by those skilled in the art in practicing the claimed invention, from a study of the drawings, the disclosure, and the appended claims.
In the claims, the word “comprising” does not exclude other elements or steps, and the indefinite article “a” or “an” does not exclude a plurality. A single element or other unit may fulfill the functions of several items recited in the claims. The mere fact that certain measures are recited in mutually different dependent claims does not indicate that a combination of these measures cannot be used to advantage.
Any reference signs in the claims should not be construed as limiting the scope.
| Number | Date | Country | Kind |
|---|---|---|---|
| 22164778.7 | Mar 2022 | EP | regional |
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/EP2023/056394 | 3/14/2023 | WO |