Claims
- 1. A compound of formula I, ##STR19## wherein one of A and D is N and the other CH;
- R.sub.1 ', R.sub.2 ' and R.sub.3 are each, independently, hydrogen or (C.sub.1-4)alkyl;
- m is 1 or 2;
- R.sub.4 and R.sub.5 are each, independently, hydrogen, halogen, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, (C.sub.2-4)acyl or trifluoromethyl; and
- X is --CH.sub.2 -- and n is 0, 1, 2 or 3, or
- X is --CO-- and n is 1, 2 or 3, or
- X is --O-- and n is 2 or 3,
- or a pharmaceutically acceptable acid addition salt thereof.
- 2. A compound according to claim 1 wherein A is CH, D is N, m is 1 and R.sub.1 ', R.sub.2 ', R.sub.3, R.sub.4, R.sub.5, X and n are as defined in claim 1, or a pharmaceutically acceptable acid addition salt thereof.
- 3. A compound according to claim 1 wherein A is N, D is CH, m is 1 and R.sub.1 ', R.sub.2 ', R.sub.3, R.sub.4, R.sub.5, X and n are as defined in claim 1, or a pharmaceutically acceptable acid addition salt thereof.
- 4. A pharmaceutical composition useful in treating schizophrenia, hypertension and cardiac disorders comprising a pharmaceutically acceptable carrier or diluent and a therapeutically effective amount of a compound of claim 1, or a pharmaceutically acceptable acid addition salt thereof.
- 5. A method of treating schizophrenia which comprises administering a therapeutically effective amount of a compound of claim 1 or a pharmaceutically acceptable acid addition salt thereof to a subject in need of such treatment.
Priority Claims (4)
Number |
Date |
Country |
Kind |
3317/82 |
May 1982 |
CHX |
|
3379/82 |
Jun 1982 |
CHX |
|
4484/82 |
Jul 1982 |
CHX |
|
4485/82 |
Jul 1982 |
CHX |
|
Parent Case Info
This is a division of application Ser. No. 498,952, filed May 27, 1983, now issued as U.S. Pat. No. 4,565,816.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4022779 |
Denzel et al. |
May 1977 |
|
4082845 |
Saari et al. |
Apr 1978 |
|
Non-Patent Literature Citations (1)
Entry |
Neumann, "Chemical Abstracts", vol. 100, 1984, Col. 100:103393t. |
Divisions (1)
|
Number |
Date |
Country |
Parent |
498952 |
May 1983 |
|