Claims
- 1. A plaster agent comprising layer a which is a water impermeable or water semipermeable film, layer b which is one tackifier layer laminated on one surface of said film, and layer d which is another tackifier layer laminated on said layer b through layer c which is an intermediary knitted fabric having a weight per unit area of 10 to 100 g/m.sup.2 comprising hollow fibers having pores extending therethrough in the outer peripheral direction and substantially free from medicine internally thereof, and at least one of said layer b and said layer d containing at least one medicine selected from the group consisting of nitric acid esters, guayazulene, camphor, menthol, salicylic acid esters, hormones, analgesics and cardiac agents, said knitted fabric having a texture wherein the sum of a number of loops in the longitudinal and lateral directions thereof is 15 to 37 loops/cm.
- 2. A plaster agent as claimed in claim 1, wherein the hollow fiber is a hollow fiber of polyethylene terephthalate.
- 3. A plaster agent as claimed in claim 1, wherein the film has a thickness of 0.5 to 4.9 .mu.m.
- 4. A plaster agent as claimed in claim 1, wherein the medicine is a nitric acid ester and the content thereof is 0.1% to 20% by weight based on the weight of the tackifier layer.
- 5. A plaster agent as claimed in claim 1, wherein each tackifier layer comprises an acrylic resin having a thickness of 5 to 100 .mu.m.
- 6. A plaster agent as claimed in claim 5, wherein the medicine is at least one compound selected from the group consisting of estradiol, estradiol benzoate, estradiol dipropionate, estradiol valerate and ethynyl estradiol and the content thereof is 0.5% to 5% by weight based on the weight of the tackifier layer.
- 7. A plaster agent as claimed in claim 6, wherein the water content in each tackifier layer is 0.5% by weight or less and the hollow fiber is composed of polyethylene terephthalate and the film has a thickness of 0.5 to 4.9 .mu.m.
- 8. A plaster agent as claimed in claim 6, wherein the tackifier layers (b layer and/or d layer) containing estradiol or its derivative contain 0.5% to 15% by weight, based on the weight of the tackifier layer, of polyvinyl pyrrolidone having a molecular weight of about 100,000 or more and the hollow fiber is composed of polyethylene terephthalate and the film has a thickness of 0.5 to 4.9 .mu.m.
- 9. A plaster agent as claimed in claim 5, wherein the medicine is a buprenorphin and the content thereof is 1% to 20% by weight based on the weight of the tackifier layer.
- 10. A plaster agent as claimed in claim 9, wherein the buprenorphin is buprenorphin hydrochloride and the hollow fiber is composed of polyethylene terephthalate and the film has a thickness of 0.5 to 4.9 .mu.m.
- 11. A plaster agent as claimed in claim 1, wherein said nitric acid ester is isosorbide dinitrate, said hormone is at least one compound selected from the group consisting of estradiol, estradiol benzoate, estradiol dipropionate, estradiol valerate, and ethynyl estradiol, and said analgesic is buprenorphin.
Priority Claims (5)
Number |
Date |
Country |
Kind |
1-451780 |
Feb 1989 |
JPX |
|
1-166040 |
Jun 1989 |
JPX |
|
1-166041 |
Jun 1989 |
JPX |
|
1-166042 |
Jun 1989 |
JPX |
|
1-214162 |
Aug 1989 |
JPX |
|
Parent Case Info
This is a Continuation of application Ser. No. 07/601,779 filed Oct. 26, 1990 now abandoned.
US Referenced Citations (3)
Foreign Referenced Citations (1)
Number |
Date |
Country |
57-31611 |
Feb 1982 |
JPX |
Continuations (1)
|
Number |
Date |
Country |
Parent |
601779 |
Oct 1990 |
|