POLYURETHANE-UREA PRIMARY REFERENCE MATERIALS

Information

• Research Project
• 2225773

• ApplicationId

  2225773

• Core Project Number

  R43HL049703

• Full Project Number

  1R43HL049703-01

• Serial Number

  49703

• FOA Number

• Sub Project Id

• Project Start Date

  4/1/1993 - 31 years ago

• Project End Date

  4/14/1994 - 30 years ago

• Program Officer Name

• Budget Start Date

  4/1/1993 - 31 years ago

• Budget End Date

  4/14/1994 - 30 years ago

• Fiscal Year

  1993

• Support Year

  1

• Suffix

• Award Notice Date

  3/29/1993 - 31 years ago

Organizations

• POLYMER TECHNOLOGY GROUP, INC.

Polyurethanes are used in a variety of biomedical devices including artificial hearts, vascular grafts, catheters, and intra-aortic balloons. This proposal presents methods for the synthesis, characterization, and fabrication of polyurethaneurea (PUU) Primary Reference Materials (PRM). The proposed program involves the synthesis of a batch of additive-free PTMO based polyurethaneurea and a batch of additive-free PEO based polyurethaneurea followed by thorough characterization of the bulk and surface properties of cast films. Polymers that are free of unwanted surface active contaminants, as determined by ESCA and static SIMS, will be fabricated into film samples, 1 x 3 x 0.005 inches, and will be packaged, sterilized and characterized. Tubing extrusion methods will be evaluated for producing small diameter tubing samples with a 4 mm ID and 10 cm long. A feasibility study will be performed to determine if it is possible to fabricate implantable quality small diameter tubing 0.5 meter long. The effect of gamma radiation on physicochemical properties of polyurethaneureas will be determined. Changes in the surface properties of the PRM as a function of time/annealing will be assessed.

IC Name

• Activity

  R43

• Administering IC

  HL

• Application Type

  1

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  837

• Ed Inst. Type

• Funding ICs

• Funding Mechanism

• Study Section

  SSS

• Study Section Name

• Organization Name

  POLYMER TECHNOLOGY GROUP, INC.

• Organization Department

• Organization DUNS

• Organization City

  BERKELEY

• Organization State

  CA

• Organization Country

  UNITED STATES

• Organization Zip Code

  94710

• Organization District

  UNITED STATES