Claims
- 1. A porous polypropylene hollow fiber membrane constructed and arranged for artificial lung use having an oxygen gas flux in the range of 100 to 1,500 liters/mm.m.sup.2.atom comprising a solid phase in an inner surface region thereof formed with particles of polypropylene closely fused and joined to give rise to a continuous phase while partially exposed through the surface thereof, a solid phase in an interior and an outer surface region thereof formed with particles of polypropylene interconnected in the direction of axis of fiber to give rise to a multiplicity of lumps of polypropylene, and an interstice between said solid phases having continuous pores interconnected in the form of a three-dimensional network, wherein pores on the outer surface of said membrane consist essentially of pores having a pore diameter of 1 .mu.m or less.
- 2. A porous polypropylene hollow fiber membrane according to claim 1, wherein the ratio of birefringent in the direction of axis thereof is in the range of 0.001 to 0.01.
- 3. A porous polypropylene hollow fiber membrane according to claim 1, wherein the porosity is in the range of 10 to 60%, and opening ratio in the inner surface in the range of o10 to 30%.
- 4. A porous polypropylene hollow fiber membrane according to claim 1 wherein the inside diameter is in the range of 150 to 300 .mu.m and the wall thickness in the range of 10 to 150 .mu.m.
- 5. A porous polypropylene hollow fiber membrane according to claim 1, wherein the average diameter of polypropylene particles is in the range of 0.1 to 2.0 .mu.m and the average pore diameter in the inner surface in the range of 0.1 to 1.0 .mu.m.
- 6. A porous polypropylene hollow fiber membrane according to claim 1, wherein said porous polypropylene hollow fiber membrane used in an artificial lung is substantially free from leakage of blood plasma or degradatin of gas-exchange capacity within 30 hours of service.
- 7. A porous polypropylene hollow fiber membrane according to claim 1, wherein said porous polypropylene hollow fiber membrane used in an artificial lung sparingly entails infliction of injury to blood cells.
- 8. An artificial lung provided with a hollow fiber membrane having an oxygen gas flux in the range of 100 to 1,500 liters/mm.m.sup.2.atom as a gas-exchange membrane, said membrane comprising a solid phase in an inner surface region thereof formed with particles of polypropylene closely fused and joined to give rise to a continuous phase while partially exposed through the surface thereof, a solid phase in an interior and an outer surface region thereof formed with particles of polypropylene interconnected in the direction of axis of fiber to give rise to a multiplicity of lumps of polypropylene, and an interstice between said solid phases having continuous pores interconnected in the form of a three-dimensional network, wherein pores on the outer surface of said membrane consist essentially of pores having a pore diameter of 1 .mu.m or less.
- 9. An artificial lung according to claim 8, wherein the ratio of birefringent of said porous polypropylene hollow fiber membrane in the direction of axis thereof is in the range of 0.001 to 0.01.
- 10. An artificial lung according to claim 8, wherein said hollow fiber membrane possesses a porosity in the range of 10 to 60% and an opening ratio in the inner surface in the range of 10 to 30%.
- 11. An artificial lung according to claim 8, wherein said hollow fiber membrane possesses an inside diameter in the range of 150 to 300 .mu.m and a wall thickness in the range of 10 to 100 .mu.m.
- 12. An artificial lung according to claim 8, which is adapted to circulate blood inside said hollow fiber membrane and blow said oxygen-containing gas outside said hollow fiber membrane.
- 13. An artificial lung according to claim 8, which is adapted to circulate blood outside said hollow fiber membrane and blow said oxygen-containing gas inside said hollow fiber membrane.
- 14. An artificial lung according to claim 8, which is substantially free from either leakage of blood plasma or degradation of gas-exchange capacity within 30 hours of extra-corporeal circulation of blood.
- 15. An artificial lung according to claim 8, which sparingly entails infliction of injury upon blood cells while in service for extra-corporeal circulation of blood.
- 16. An artificial lung according to claim 8, wherein the average diameter of polypropylene particles in said hollow fiber membrane is in the range of 0.1 to 2.0 .mu.m and the average pore diameter in the inner surface in the range of 0.1 to 1.0 .mu.m.
Priority Claims (2)
Number |
Date |
Country |
Kind |
62-8982 |
Jan 1987 |
JPX |
|
62-56728 |
Mar 1987 |
JPX |
|
Parent Case Info
This application is a divisional of application Ser. No. 07/392,988, filed Aug. 25, 1989 now U.S. Pat. No. 5,139,529.
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Divisions (1)
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Number |
Date |
Country |
Parent |
392988 |
Aug 1989 |
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