This invention relates to a portable temperature controlled container. More specifically, the present invention relates to a portable temperature controlled container for transportation of highly-temperature-sensitive goods such as pharmaceuticals and vaccines.
The transportation of highly-temperature-sensitive pharmaceuticals and vaccines (hereinafter simply referred to as goods) is a major problem facing the distributers of those goods and the healthcare workers charged with administering those goods. If these goods are subjected to a temperature outside their acceptable temperature storage range, even for a short period of time, the goods will spoil. In some instances, spoiling will result in the goods being less effective than would otherwise be the case and in other instances, the goods may become dangerous to administer and they may represent a significant health risk to the intended recipient. Accordingly, it is essential that the distributers of the goods ensure that the goods are maintained within the desired temperature range from the time of production to the time of administration.
Once produced and prior to distribution to remote locations, the goods are stored at a central hub in an environmentally-controlled warehouse facility. In some cases, the goods are transported in environmentally-controlled vehicles to regional hubs where the goods are again stored in an environmentally-controlled warehouse facility before distribution. This part of the distribution chain is not seen as problematic. Of particular concern is the so-called “last mile” of the distribution chain where the goods are transported from a temperature-controlled facility to the location that they are to be administered. It is absolutely essential that the goods are maintained within their desired temperature range over the so-called “last mile”. In order to protect the goods over the last mile, they are often transported in portable temperature controlled containers.
The known temperature controlled containers typically comprise an insulated box constructed from polystyrene or other insulating material. The goods are carefully placed inside the box and the box is then often packed with ice (in hot climates) to keep the goods inside the insulated box cool. The goods are then transported over the “last mile” to the intended destination.
There are however, numerous problems with this solution. First of all, the temperature at which the goods are stored is not accurately controlled and there is no guarantee that the goods will be maintained within the desired temperature range. Secondly, it is difficult to determine precisely how much ice will be required for a given journey. If too much ice is packed into the container, the goods may freeze thereby spoiling the goods. On the other hand, if too little ice is packed into the container, the ice may have melted before the goods have been delivered and the goods may spoil prior to delivery. Thirdly, in some instances, the location will be very remote and may take several days to reach. In those instances it would be necessary to restock the ice on one or more occasions during the journey but this is often not possible. Furthermore, in those instances where the location is very remote, the container may experience significant variations in ambient temperature over the course of the journey, from extreme heat to extreme cold, and this is not addressed by the proposed solution.
There are however more complex solutions that involve the use of electromechanical systems to control the temperature of the goods in the portable container over the last mile. Electromechanical systems for refrigeration have existed for many years and while relatively efficient, they suffer from two main drawbacks. First of all, these systems are not considered to be particularly robust which makes it difficult for such systems to be reliable when exposed to the mechanical stresses experienced during journeys over rough terrain. Secondly, battery power must be relied upon and it is challenging to design lightweight, cost effective devices that will keep small quantities of product at correct temperatures for complete journey times. Generally speaking, many of the known designs that use electromechanical systems are too complex and therefore too expensive for the so-called “last mile” application addressed by this invention.
One device that has been proposed that attempts to address some of these problems is the device described in Chinese Patent Application No. CN103075856 in the name of Shanghai Polytechnic University. This device proposes to use a semiconductor cooling system and insulation comprising copper tubes filed with a phase changing material that will keep the contents cool when the semiconductor cooling system is not operational. Another device known to the applicant is GB2501223 in the name of Mars Incorporated. GB2501223 describes a cool storage cabinet used for storing chocolate in hot climates that has a thermoelectric cooling device and a phase change material. The phase change material is used to keep the contents of the cabinet cool during power outages when the thermoelectric cooling device is not operational.
It is an object of the present invention to provide a portable temperature controlled container that overcomes at least some of the problems with the known devices. It is a further object of the present invention to provide a useful choice to the consumer.
According to the invention there is provided a portable temperature controlled container comprising:
By having such a portable temperature controlled container, it will be possible to maintain the temperature of the goods within a specific range, for substantial periods of time at a relatively low cost. This is achieved by having a thermoelectric device and a phase change material configured so that the thermoelectric device is operable to remove energy in the form of heat from one of the storage compartment and the first phase change material and transfer that energy in the form of heat to the other of the storage compartment and the first phase change material as required. This configuration has been found to significantly reduce the power requirement of the container thereby reducing the overall cost of the container and increasing the length of time that the goods may be safely stored in the container. Furthermore, due to the use of a thermoelectric device, the configuration described will be more robust than other known offerings.
In one embodiment of the invention there is provided a portable temperature controlled container in which the first thermoelectric device is operable to remove energy in the form of heat from the storage compartment and transfer that energy in the form of heat to the first phase change material.
In one embodiment of the invention there is provided a portable temperature controlled container in which there is provided a second thermoelectric device controlled by the controller, a heat sink in thermal communication with the second thermoelectric device, an air passageway through the body, and a fan operable to deliver airflow through the air passageway over the heat sink. An important advantage of this configuration of container is that once it arrives at the remote destination, if an alternative electricity supply is available, the thermoelectric devices may be operated from the alternative electricity supply so that the container may be operated as a normal mains powered unit, thereby obviating the need for a dedicated storage unit at the destination and prolonging the length of time that the goods may be stored in the container prior to being administered. Furthermore, by having the additional components, it will be possible to re-energise the phase change material without removing the phase change material from the container.
In one embodiment of the invention there is provided a portable temperature controlled container in which the first thermoelectric device is sandwiched between the storage compartment and the first phase change material and the second thermoelectric device is sandwiched between the first phase change material and the heat sink.
This is seen as a particularly preferred embodiment of the present invention. There are numerous benefits to providing this configuration. By having such a configuration, the first phase change material will act as a barrier insulating layer between the storage compartment and the heat sink. If the storage compartment is to be kept cool or indeed is to be regulated in a narrow temperature range, this is particularly advantageous as the heat sink could otherwise have a significant effect on the temperature in the storage compartment. Secondly, after a long journey has been completed, the phase change material can be recharged very quickly by operating the second thermoelectric devices and the excess heat can be dissipated through the heat sink with relative ease. At the same time, the temperature in the storage compartment can be regulated in the normal manner using the first thermoelectric device and the first phase change material.
In one embodiment of the invention there is provided a portable temperature controlled container in which the storage compartment, first thermoelectric device, first phase change material, second thermoelectric device and heat sink are arranged in a stack configuration with the storage compartment located at the top of the stack, the first thermoelectric device located immediately below the storage compartment, the first phase change material located immediately below the first thermoelectric device, the second thermoelectric device located immediately below the first phase change material and the heat sink located immediately below the second thermoelectric device, at the bottom of the stack.
In one embodiment of the invention there is provided a portable temperature controlled container in which there is provided a heating element controlled by the controller in thermal communication with the storage compartment.
This is seen as another particularly useful embodiment of the present invention. By having a heating element in thermal communication with the storage compartment, the first phase change material can be used to absorb excess heat delivered from the storage compartment by the first thermoelectric device and the heating element can be used to deliver heat to the storage compartment if required. This will save having to provide a second phase change material to provide heat to the storage compartment if it is required. It has been found that the amount of energy typically required to heat the storage compartment is less than the energy required to cool the storage compartment during the expected operating conditions of the device. Therefore, if a heating element is provided, it will not require significant amounts of battery power to operate and will allow for more phase change material used in cooling of the storage compartment. This will lead to a container that can transport the goods for longer between charging operations.
In one embodiment of the invention there is provided a portable temperature controlled container in which the second thermoelectric device is sandwiched between the first phase change material and the heat sink, and the first thermoelectric device is sandwiched between the storage compartment and the heat sink, the first thermoelectric device being in thermal communication with the first phase change material via the heat sink and the second thermoelectric device. Again, this configuration will allow the phase change material to be recharged (i.e. refrozen) in a fast, efficient manner.
In one embodiment of the invention there is provided a portable temperature controlled container in which there is provided: a third thermoelectric device controlled by the controller in thermal communication with the heat sink, a second phase change material in thermal communication with the third thermoelectric device, the first thermoelectric device being in thermal communication with the second phase change material via the heat sink and the third thermoelectric device.
This is seen as a useful embodiment of the present invention. By having a second phase change material and a third thermoelectric device, one of the phase change materials can be used to cool the storage compartment and the other phase change material can be used to heat the storage compartment. In this way, the container will be able to regulate the temperature of the goods inside the container in both extreme hot and extreme cold conditions without drawing large amounts of power from the battery. This will provide a device that can operate efficiently across a wider range of environmental conditions in a cost effective manner. Furthermore, with this configuration, it will be possible to restore the properties of both of the phase change materials in a fast, efficient manner once the device is connected to a mains supply after use.
In one embodiment of the invention there is provided a portable temperature controlled container in which the first thermoelectric device is sandwiched between the storage compartment and the first phase change material and the second thermoelectric device is sandwiched between the storage compartment and the heat sink. This is seen as a further useful alternative embodiment of the present invention.
In one embodiment of the invention there is provided a portable temperature controlled container in which there is provided: a third thermoelectric device controlled by the controller in thermal communication with the storage compartment, and a second phase change material in thermal communication with the third thermoelectric device, and in which the first thermoelectric device is operable to remove energy in the form of heat from the storage compartment and transfer that energy in the form of heat to the first phase change material and in which the third thermoelectric device is operable to remove energy in the form of heat from the second phase change material and transfer that energy in the form of heat to the storage compartment.
Again, this is seen as a useful embodiment of the present invention. By having a second phase change material and a third thermoelectric device, one of the phase change materials will be used to cool the storage compartment and the other phase change material will be used to heat the storage compartment. In this way, the container will be able to regulate the temperature of the goods inside the container in both extreme hot and extreme cold conditions without drawing large amounts of power from the battery.
This will provide a device that can operate efficiently across a wider range of environmental conditions in a cost effective manner.
In one embodiment of the invention there is provided a portable temperature controlled container in which the second phase change material undergoes a solid to liquid phase transition upon heating of the second phase change material.
In one embodiment of the invention there is provided a portable temperature controlled container in which the second phase change material has a phase transition temperature within 4° C. of the phase transition temperature of the first phase change material.
In one embodiment of the invention there is provided a portable temperature controlled container in which the second phase change material comprises a eutectic composition.
In one embodiment of the invention there is provided a portable temperature controlled container in which the second phase change material is water.
In one embodiment of the invention there is provided a portable temperature controlled container in which the first phase change material undergoes a liquid to solid phase transition upon cooling of that phase change material.
In one embodiment of the invention there is provided a portable temperature controlled container in which the first phase change material has a phase transition temperature of between −2° C. and 8° C.
In one embodiment of the invention there is provided a portable temperature controlled container in which the first phase change material has a phase transition temperature of 0° C.
In one embodiment of the invention there is provided a portable temperature controlled container in which the first phase change material is water.
In one embodiment of the invention there is provided a portable temperature controlled container in which the first phase change material is a eutectic composition.
In one embodiment of the invention there is provided a portable temperature controlled container in which the thermoelectric device is a peltier device. A peltier device is seen a particularly suitable device due to the robustness of the device and furthermore due to the fact that the device may be operated to either provide heat to or cool the contents of the container.
In one embodiment of the invention there is provided a portable temperature controlled container in which the insulation layer comprises a vacuum insulation panel. Vacuum insulation panel is seen as a very useful insulation to use with the container as it will be relatively compact compared with other solutions and is capable of providing excellent insulation performance. Furthermore, this will help to allow a smaller battery to be provided in the container. The vacuum insulation panel could be a Nanopore (Registered Trade Mark®) vacuum insulation panel.
In one embodiment of the invention there is provided a portable temperature controlled container in which the insulation layer has a thermal conductivity value of the order of 0.005 W/m·K.
In one embodiment of the invention there is provided a portable temperature controlled container in which there is provided a heat transfer block intermediate the first phase change material and the thermoelectric device in thermal communication therewith. By providing a heat transfer block intermediate the phase change material and the thermoelectric device, this will enable insulation to be packed around the storage compartment ensuring better insulation of that compartment.
In one embodiment of the invention there is provided a portable temperature controlled container in which there is provided a heat transfer block intermediate the second phase change material and the thermoelectric device in thermal communication therewith.
In one embodiment of the invention there is provided a portable temperature controlled container in which the storage compartment has a volume of between 10 and 20 litres.
The invention will now be more clearly understood from the following description of some embodiments thereof given by way of example only with reference to the accompanying drawings, in which:
Referring to
Referring to
The container 1 further comprises a first phase change material 31, a thermoelectric device, again provided by way of a peltier device 33, and a heat transfer block 35 intermediate the peltier device 33 and the phase change material 31. The peltier device 33 is in thermal communication with the storage compartment and the first phase change material 31. There is further provided a second phase change material 37, a thermoelectric device, again provided by a peltier device 39, and a heat transfer block 41 intermediate the peltier device 39 and the second phase change material 37. The peltier device 39 is in thermal communication with the storage compartment and the second phase change material 37.
The container 1 body 3 comprises an outer shell 43, an inner shell 45, and an insulation layer 47 between the outer shell and the inner shell. The inner shell defines the storage compartment 15 which is effectively surrounded by the insulation layer 47. The insulation layer preferably comprises vacuum insulation panels (VIP) having a thermal conductivity value of the order of 0.005 W/m·K. There is further provided a temperature sensor 49 located internal the storage compartment 15, a rechargeable battery 51, and a controller 52 in communication with the temperature sensor 49 and operable to control the peltier devices 23, 33, 39.
In the embodiment shown, the first phase change material 31 undergoes a liquid to solid phase transition upon cooling of that phase change material and is operable to cool the storage compartment 15 as will be explained in greater detail below. In the embodiment shown, the first phase change material 31 undergoes the transition when cooled to approximately 4° C. The second phase change material 37 also undergoes a solid to liquid phase transition upon heating of that phase change material and is operable to heat the storage compartment, as will be explained in greater detail below. The second phase change material 37 undergoes the solid to liquid phase transition when heated to approximately 6° C. The first phase change material 31 and the second phase change material 37 do not have the same transition temperature and in some instances there will be a buffer zone of the order of approximately 1° C. to 4° C. between the two phase transition temperatures.
The operation of the device will now be explained in greater detail by reference to
While the peltier device 23, fan 19, heat sink 21, and heat transfer block 25 operate to cool the storage compartment 15, the peltier device 33 is operated to cool the first phase change material 31 below 4° C. thereby freezing the first phase change material 31 and if necessary the peltier device 39 is operated to heat the second phase change material above 6° C., thereby melting the second phase change material 37. It will be understood that temperature sensors may also be provided to measure the temperature of each of the first and second phase change materials 31 and 37 and this data will be delivered to the controller 52 so that the controller can operate the peltier devices 33, 39 appropriately. The internal rechargeable battery 51 is fully charged.
Referring to
Referring to
If the ambient conditions of the external environment are above the desired temperature of 5° C., this heat will cause the temperature inside the storage compartment 15 to rise over time, as recorded by the temperature sensor 49. In order to avoid the storage compartment overheating thereby spoiling the goods, the controller operates the peltier device 33 to transfer any excess heat away from the storage compartment 15 and into the frozen, solid phase change material 31 and maintain the temperature in the storage compartment at the desired temperature of 5° C. If the ambient conditions of the external environment are below the desired temperature of 5° C., this will cause the temperature inside the storage compartment to lower over time, as recorded by the temperature sensor 49. In order to avoid the storage compartment overcooling thereby spoiling the goods by allowing the goods to freeze, the controller operates the peltier device 39 to transfer heat stored in the molten phase change material 37 into the storage compartment and maintain the temperature in the storage compartment at the desired temperature of 5° C. In this mode, it is envisaged that there will be sufficient battery power to run the peltier devices and sufficient capacity in the phase change materials 31, 37 to maintain the temperature in the storage compartment at the desired temperature of 5° C. for at least 48 hours.
Referring to
Referring to
In
Referring to
It will be understood that to achieve this, the fan 19, heat sink 21, peltier device 23 and heat transfer block 25 will be operated by the controller (not shown) in such a fashion to either provide sufficient heat into the storage compartment for onward delivery to the second phase change material 37 by the peltier device 39 or to remove excess heat from the storage compartment 15 and from the first phase change material and to regulate the temperature in the storage compartment 15 to the desired temperature of 5° C. In the embodiments shown, the container 1 and components are operated so that the rate of energy transfer by the peltier device 33 is 32 Watts. In the embodiment shown, the ambient temperature outside the container is room temperature, 20° C., however the container may have experienced far hotter and colder temperatures during the previous journey.
Referring to
Referring to
Referring now to
In the embodiment of portable temperature controlled container 61 shown in
One benefit of this embodiment of the invention is that when the device is being “recharged”, that is, when the first phase change material is being refrozen and the second phase change material is being melted, the heat does not have to pass through the storage compartment 15. This is beneficial for two reasons: First of all, the “recharge” time will be reduced. The peltier devices typically operate at about a 30% efficiency. In other words, it takes about 100 Watts of power to pump 30 Watts of heat. In the embodiment described with respect to
In addition to the foregoing, in the embodiment shown in
Referring now to
The storage compartment 15, the first thermoelectric device 33, the first phase change material 31, the second thermoelectric device 23 and heat sink 63 are arranged in a stack configuration with the storage compartment 15 located at the top of the stack, the first thermoelectric device 33 located immediately below the storage compartment 15, the first phase change material 31 located immediately below the first thermoelectric device 33, the second thermoelectric device 23 located immediately below the first phase change material 31 and the heat sink 63 located immediately below the second thermoelectric device 33, at the bottom of the stack.
In use, the phase change material 31 is water that is converted into ice before transit. The water 31 is converted into ice by plugging the container into a mains electricity supply 53 and the controller 52 thereafter operating the peltier device 23 to freeze the water. The peltier device 23 will deliver the heat from the phase change material 31 into the heat sink 63 and the heat from the heat sink 63 will be dissipated to the environment with the aid of a fan 65. When the water 31 is frozen, the container 81 will be ready for use in the transportation of goods.
During transit, the storage compartment 15 is kept cool at the desired temperature by operating the peltier device 33 to transfer heat from the storage compartment 15 into the phase change material 31. In the embodiment shown, 4 litres of water are provided as the phase change material 31. It is calculated that this amount of phase change material will allow the container to maintain goods at 5° C. for at least 48 hours at a temperature of 43° C.
If it is necessary to provide heat to the storage compartment 15, rather than operating a peltier device and a separate phase change material as described in relation to the first two embodiments, the heating element 83 can be operated. It is believed that the battery 51 will provide sufficient power to operate the heating element 83 for the limited amount of time and current draw that it will need to operate. As the rate of exchange of energy out of the container at −20° C. is lower than the rate of exchange of energy into the container at 43° C., less energy will be required to heat the container. If the container is used to transfer goods through a desert or over mountains, it is not inconceivable that the container will experience both high and low temperatures during its journey. However, the highs tend to be more extreme than the lows compared with the desired storage temperature of the goods and therefore less energy is required to adjust for low temperature conditions than required to adjust for high temperature conditions.
Once at the destination, the phase change material can be replenished (i.e. refrozen) by plugging the container 81 into the mains electricity or other external supply once more and operating the peltier device 23 to cool the phase change material. It will be understood that the flaps 67, 69 will be opened and the fan 65 operated to dissipate heat from the heat sink caused by the operation of the thermoelectric (peltier) device 23.
One significant advantage of the configuration shown is that the phase change material may be refrozen quickly by operating the peltier device 23 at high power. This can be done as the peltier device will not adversely affect the temperature in the storage compartment 15 as the storage compartment 15 is insulated from the peltier device 23 by the layer of phase change material therebetween.
Another significant advantage of this embodiment is that the container 81 can continue to be used to store goods while plugged into the mains and while the phase change material 31 is being refrozen. The peltier device 33 can continue to operate feeding heat into the phase change material 31 while the other peltier device 23 operates (albeit typically at a faster rate) to cool the phase change material 31. Furthermore, as the replenishment or refreezing of the phase change material 31 does not require transition of energy through the storage compartment 15, goods can still be stored in the storage compartment.
A third advantage of the embodiment shown in
In the embodiments shown, the container will be appropriately sized so that it can transport of the order of 10 litres worth of pharmaceuticals and/or vaccines. In order to provide an internal compartment that is capable of holding 10 litres worth of product, it is envisaged that the external dimensions of the container will be of order of 570 mm (long)×400 mm (wide)×350 mm (high) and the container will have an unladen weight of the range of 15 to 30 kg. In those embodiments with two phase change materials and two thermoelectric devices where the container is able to operate in both hot and cold environments, the container will be designed to operate in external temperatures ranging from +40° C. to −20° C. and will have sufficient battery power and phase change material stores to operate at those temperatures for a minimum of 48 hours. The battery power will preferably be provided by 7 AHr, 12V Lead-Acid Battery. Alternatively, the battery could be provided by way of one or more 10 AHr, 4.2V Lithium Ion rechargeable batteries.
It will be seen from
Another important aspect of the present invention is that the container is provided with a temperature sensor that is used to monitor the temperature of the storage compartment 15. The readings from this sensor may be taken periodically, such as every few seconds, every few minutes or every hour. The readings from the sensor are sent to the controller where they are analysed and indeed may be logged in controller memory. It is envisaged that it would be preferable to have a memory that can log of the order of 10,000 records. The temperature sensor may be wired or may communicate with the controller over a wireless communication technology, such as, but not limited to, Bluetooth. Indeed, the container 1 may be provided with a data port for receipt of a plug or other connector to allow programming or communication with the controller by an external device or indeed the controller may be adapted for wireless communications.
Preferably, the container will be provided with a display such as, but not limited to, an LCD display. This display could have a timer illustrated thereon indicating the battery charge state and or the amount of battery charge remaining and the time remaining before the battery is fully discharged and no longer capable of operating the peltier devices 33, 39. Furthermore, preferably the container will be provided with straps for carriage and securing the container in transit.
In the embodiments shown in
In the embodiments shown, the substance used in the first and the second phase change materials could be water, water with an additive to vary the freezing point of water, or indeed another liquid that has a suitable phase transition temperature. Pure (i.e. distilled) water could be provided in one or both chambers for the phase change material. The phase change materials will be stored in reservoir containers that are either expansible or that have means to accommodate expansion of the phase change material as it transitions from a liquid to a solid. This is to prevent rupture of the reservoir containers.
It will be understood that the volume of phase change materials required will depend on a number of factors including: 1) the length of time that the phase change material is required to operate; 2) the conditions in which the phase change material is required to operate; and 3) the characteristics of the phase change material including the amount of energy that may be stored per unit volume (the energy storage density) of the phase change material. It is envisaged that approximately 2 litres of phase change material used to cool the storage compartment and approximately 1 litre of phase change material used to heat the storage compartment will be sufficient for most typical materials and operating conditions. In the third embodiment of the invention shown in
Throughout the specification, the portable temperature controlled container 1, 61, 81 has been described for use in the transport of highly-temperature-sensitive goods such as pharmaceuticals and vaccines. However, it will be understood that the present invention, although particularly suited for those purposes, is not so limited. Indeed, the container according to the present invention could be used to transport other items including, but not limited to, organs or foodstuffs. Furthermore, it is envisaged that the container may be designed to operate at different temperature ranges than those described throughout the specification and indeed the device may vary from the dimensions specified above without departing from the scope of the present invention.
In this specification the terms “comprise, comprises, comprised and comprising” and the terms “include, includes, included and including are deemed totally interchangeable and should be afforded the widest possible interpretation.
The invention is in no way limited to the embodiment hereinbefore described but may be varied in both style and construction within the scope of the claims.
Number | Date | Country | Kind |
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1318405.6 | Oct 2013 | GB | national |
Filing Document | Filing Date | Country | Kind |
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PCT/EP2014/072359 | 10/17/2014 | WO | 00 |
Publishing Document | Publishing Date | Country | Kind |
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WO2015/055836 | 4/23/2015 | WO | A |
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5522216 | Park | Jun 1996 | A |
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20100186423 | Veltrop | Jul 2010 | A1 |
20100307168 | Kohl | Dec 2010 | A1 |
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Number | Date | Country |
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102005972 | Apr 2011 | CN |
103075856 | May 2013 | CN |
3528731 | Mar 1986 | DE |
2501223 | Oct 2013 | GB |
199316667 | Sep 1993 | WO |
200102268 | Jan 2001 | WO |
Number | Date | Country | |
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20160243000 A1 | Aug 2016 | US |