PRECHRONIC DOSED WATER STUDY OF DIPROPYLENE GLYCOL

Information

• Research Project
• 3642356

• ApplicationId

  3642356

• Core Project Number

  N01ES095277

• Full Project Number

  N01ES095277-000

• Serial Number

  95277

• FOA Number

• Sub Project Id

• Project Start Date

  9/15/1989 - 35 years ago

• Project End Date

  -

• Program Officer Name

• Budget Start Date

  9/15/1989 - 35 years ago

• Budget End Date

  5/14/1991 - 33 years ago

• Fiscal Year

  1989

• Support Year

• Suffix

• Award Notice Date

  -

Organizations

• ARTHUR D. LITTLE, INC.

The objective of this project is to characterize dose-response relationships and toxicity of dipropylene glycol administered by dosed- water to rats and mice in 14-day repeated-dose and 90-day subchronic studies. At the end of each study, all animals will be given gross and microscopic histopathologic evaluations. Hematology, clinical chemistry, urinalysis, and sperm morphology/vaginal cytology will be performed in the 90-day study. The results of each study will be used by NTP to establish doses to be used in the next study (i.e., the 14-day results for the 90-day study; the 90-day results for a possible chronic study).

IC Name

• Activity

  N01

• Administering IC

  ES

• Application Type

  1

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  114

• Ed Inst. Type

• Funding ICs

• Funding Mechanism

• Study Section

• Study Section Name

• Organization Name

  ARTHUR D. LITTLE, INC.

• Organization Department

• Organization DUNS

• Organization City

  CAMBRIDGE

• Organization State

  MA

• Organization Country

  UNITED STATES

• Organization Zip Code

  02140

• Organization District

  UNITED STATES