Patent Application
20150344290
The present invention relates to a precision distributor for the controlled dispensing of liquid products, medicines in particular.
As known, many medicines must be distributed under strictly controlled conditions and in very precise amounts; particular devices capable of dispensing extremely precise amounts of the necessary product in total safety have therefore been studied for this type of pharmaceuticals.
In particular, when the medicines are administered in liquid form (such as, for example, the case of methadone), said distributors allow to draw a predetermined amount of liquid from a feeding reservoir by means of a peristaltic type pump, which amount of liquid is then poured into a cup to be taken by the patient.
Furthermore, said distributors are generally controlled by a computer for identifying and managing the administrations required for the various patients.
As mentioned above, the distributors of this type must obviously guarantee maximum accuracy, this aspect being of particular concern in the administration of methadone, because of the importance and sensitivity of the treated cases and for the need to be able to certify the amounts of methadone which are actually supplied with precision.
Patent EP 1 1 65 010 (by the Applicant) describes a methadone dispenser provided with two peristaltic pumps, the hydraulic circuit of which comprises a recirculation sector of the treated liquid.
The recirculation allows to provide repeatable initial conditions identically at each dispensing operation and the circuit is additionally provided with an intermediate reservoir, different from the feeding bottle, which is used to bleed possible air bubbles and as a control point of the amount of liquid present in the circuit.
Notwithstanding the considerable advantage of the dispenser as described above with respect to those previously known, it also does not fully satisfy the precision needs, and it is thus an object of the present invention to make a distributor for liquid products, and in particular methadone, of even higher precision for dispensing and for calculating the treated amounts during operation.
A distributor of liquid methadone comprising a cooling device appropriately arranged in the hydraulic circuit is described.
The present invention allows to solve the aforesaid problems by virtue of a dispenser of the type described in the aforesaid patent EP 1 165 010 further comprising a cooling device.
With reference to accompanying
The bottle 1 may be provided with identification means which may be read by appropriate sensors 14, while the pump 2 is preferably a peristaltic pump.
In a preferred embodiment, said means 15 are preferably of the RFID radiofrequency type, according to a recognition system known in itself, while corresponding sensors 14 are fixed to the apparatus and connected to the control unit of the apparatus which verifies destination volumes and dispensing operations.
The temperature probe 34 manages the temperature compensation of the dispensed liquid thereby maximizing measurement accuracy. Compensation is by correction according to a density reference value calibration curve corrected to the production temperature of 20° C.
The purpose of the cooling device 7 is to facilitate keeping the temperature of the liquid in the neighborhood of the terminal calibration value (20° C.) thus reducing, in practice, the variations introduced by the density variations of the liquid according to temperature, and may additionally cool the liquid to increase its pleasantness.
For example, said device 7 may consist of a Peltier cell, and start operation only when required to increase measurement accuracy when ambient temperature is high.
Advantageously, the pump 4 is of the ceramic piston type actuated by a stepper motor and in which the amount of displaced liquid in each cycle, of known duration, is precisely known.
Preferably, the pump 4 is provided with a recirculation (rinse-gland) circuit 53, which works as a liquid seal (water and glycerol) and is managed by a micro-pump (8) for precluding the migration of the measured liquid beyond the parallel circuit, preventing it from reaching the rear part of the pump. This also reduces the probability of the piston seizing in the cylinder.
It is apparent that the part of the hydraulic circuit which comprises the reservoir 3, the solenoid valve 5, the cooling device 7 and the pump 4 constitutes a recirculation circuit in which the liquid may be circulated by means of the pump 4 and the three-way valve 5.
The implemented liquid recirculation and loading system allows to obtain the required measurement precision from the first dispensing operation without needing priming dispensing operations of the apparatus with respective dispersion of the liquid.
In operation, the peristaltic pump 2 sucks the liquid from the bottle 1 and sends it to the reservoir 3 to reach, and subsequently keep, an appropriate level, which is detected by the probes 31-33. If the level is sufficient, the pump 4 will start recirculating the liquid until the pipes are surely and completely filled.
At the first dispensing operation, the control unit opens the dispensing valve 5 (obviously closing the recirculation way) for the dispensing time of the required amount of liquid.
The pump 4 will run a predetermined number of cycles if pauses of use occur between two dispensing operations which could cause changes of the state of the liquid or deviations with respect to the predetermined conditions at start of dispensing.
In order to guarantee the exact repetition of each dispensing operation, the pump 4 is further provided with means for determining an initial “zero”, from which the measurement of the amount being dispensed starts. According to the invention, the pump 4 is thus “reset” at each dispensing operation and returned to a start of dispensing position.
The aforesaid means consist of an electromagnetic proximity sensor, which works as a reference of the stroke of the piston of the pump and controls the advancement of the stepper motor.
The steps of the dispensing process of the liquid are (see
Furthermore, in case of prolonged inactivity between subsequent dispensing operations, the recirculation routine 02 is run to prevent possible changes to the state of the liquid (phase separations, formation of air bubbles etc.) present in the circuit of the pump 4.
| Number | Date | Country | Kind |
|---|---|---|---|
| FI2014A000131 | May 2014 | IT | national |
