The present disclosure relates to a syringe filled with a resin composition and a method for storing the resin composition.
Currently, a sealing resin composition may be filled in the syringe before being shipped, and then frozen and transported in some cases. Conventionally, the sealing resin composition has been filled so as not to contact air inside the syringe, when the plunger contacts a liquid level of the sealing resin composition (for example, PATENT LITERATURE 1).
However, in the conventional filling method, when a customer thaws the sealing resin composition before use, there is a problem that a gap is generated between an inner surface of the syringe and the resin composition to generate a void due to a contraction difference caused by a difference in thermal expansion coefficient between the resin composition and the syringe. Due to generation of the void, when using the syringe, problems occur such that discharging of the resin composition is interrupted, or a discharge amount of the resin composition is not stable.
An object of the present disclosure is to provide the filled syringe and the method for storing the resin composition, which can suppress the generation of the void between the resin composition and the inner surface of the syringe.
The present inventors have found the following. That is, a space is provided between the plunger and the resin during storage. Air bubbles generated between the resin composition and the inner surface of the syringe, which are generated upon thawing, are moved to the space between the plunger and the resin. Thus, when using the resin composition, it is possible to prevent the air bubbles from remaining as the void between the resin composition and the inner surface of the syringe.
The present disclosure relates to the filled syringe and the method for storing the resin composition, in which the above problems are solved by having the following configuration.
According to the present disclosure [1], it is possible to provide the filled syringe which can suppress the generation of the void between the resin composition and the inner surface of the syringe.
According to the present disclosure [8], it is possible to provide the method for storing the resin composition, which can suppress the generation of the void during storage.
The filled syringe of the present disclosure (hereinafter referred to as “filled syringe”) includes a syringe, a plunger, and a resin composition. When the longitudinal direction of this syringe is a vertical direction and the plunger in the syringe is above the resin composition, a ratio of a cross-sectional area of the plunger (hereinafter referred to as “plunger cross-sectional area” as appropriate) at a position of a liquid level at top of the resin composition to a cross-sectional area enclosed by an inner surface of the syringe (hereinafter referred to as “syringe cross-sectional area” as appropriate) at the same position as the liquid level at the top of the resin composition is 95% or less.
As can be seen from
When using the filled syringe, after returning a temperature of the filled syringe 1 to room temperature, a head cap 40 is removed and the plunger 20 is pushed downward by a rod (not shown). In this manner, air can be discharged upwardly of the plunger 20 by bringing the plunger 20 into contact with the liquid level 31 at the top of the resin composition. Therefore, it is possible to prevent discharge of the resin composition from being interrupted when using the filled syringe. As a result, a discharge amount of the resin composition can be stabilized. In addition, a needle cap 50 can be removed to attach a needle (not shown in
Here, the plunger 20 is not particularly limited as long as it has a function of pushing the resin composition 30 in the syringe 10 out to the needle side. The plunger 20 may also be referred to as a piston or the like.
Note that when an interface at the top of the resin composition 30 has a fillet, a position of the interface except the fillet is the liquid level 31 at the top of the resin composition 30.
The temperature of the filled syringe 1 is preferably −60 to 0° C., more preferably −20° C. or less, and still more preferably −40° C. or less, from the viewpoint of ease of exhibiting effects of the present disclosure.
Similarly, from the viewpoint of the ease of exhibiting the effects of the present disclosure, a distance between the liquid level 31 at the top of the resin composition 30 and a position in which a wiper 21 of the plunger 20 contacts the inner surface 11 of the syringe 10 is preferably 0.2 mm or more, and more preferably 1 mm or more. Here, the wiper 21 refers to a tip portion (lower end portion in
Characteristics of the resin composition 30 are not particularly limited. For example, the resin composition 30 may be insulating or conductive. However, the resin composition containing at least one member of the group consisting of an epoxy resin and an acrylic resin is preferable because the effects of the present disclosure are easily exhibited.
A material of the syringe 10 is not particularly limited. However, from the viewpoint of durability of the syringe, the syringe 10 is preferably made of polypropylene or polyethylene, and more preferably polypropylene. An internal volume of the syringe is 3 cm3, 5 cm3, 10 cm3, 30 cm3, 50 cm3, 55 cm3 or more from the viewpoint of the ease of exhibiting the effects of the present disclosure.
The material of the plunger 20 is preferably PP or PE from the viewpoint of durability. The tip portion (lower end portion in
By using the above-described filled syringe and storing the resin composition, it is possible to suppress the generation of the void during storage.
The present embodiment will be described by way of Examples. However, the present embodiment is not limited to the Examples. Note that in the following examples, parts and % indicate parts by mass and % by mass unless otherwise specified.
In 41.9 parts by mass of liquid acrylic resin (product name: A-DCP) manufactured by Shin-Nakamura Chemical Co., Ltd., 58 parts by mass of silica filler was dispersed by a roll mill. Then, 0.1 parts by mass of an organic peroxide as a curing agent was blended to the obtained mixture of the acrylic resin and the silica filler.
The syringe was filled with the resin composition under conditions shown in Tables 1 and 2. The plunger was then inserted into the syringe from above. In this way, the filled syringe was prepared. Tables 1 and 2 show syringe material, syringe size, plunger type, filling amount, storage temperature, liquid level-space area, and liquid level-plunger height used. Here, as shown in
At the storage temperature shown in Tables 1 and 2, the filled syringe was kept frozen for 4 hours or more. The filled syringe kept frozen was kept at room temperature for 1 hour. Thereafter, presence or absence of voids in the filled syringe was evaluated by visual observation. Tables 1 and 2 show the results.
At the storage temperature shown in Tables 1 and 2, the filled syringe was kept frozen for 4 hours or more. The filled syringe kept frozen was kept at room temperature for 1 hour. Thereafter, the plunger was pushed in, and a 25G needle was attached to the filled syringe. A line of the resin composition was drawn until all the resin composition inside the syringe was discharged using a table-top type liquid agent application robot 2000N series manufactured by SAN-EI TECH Ltd. The presence or absence of interruption of the line was evaluated by visual observation. Tables 1 and 2 show the results.
1) Plunger type
1: 5112PE 30CC/55CC NO-DRIP WIPER PISTON (EFD)
1) Plunger type
1: 5112PE 30CC/55CC NO-DRIP WIPER PISTON (EFD)
2: In-house produced plunger shown in
3: 5196 PRS CARTRIDGE PLUNGER WITH SKIRT (produced by SEMCO)
4: 5111PE 10 cc SMOOTH FLOW WIPER PISTON (EFD)
As can be seen from Tables 1 and 2, neither void generation nor discharge interruption was observed in all of Examples 1 to 15. In contrast, the void was generated and the discharge was interrupted in Comparative Example 1. In Comparative Example 1, the liquid level-space area is 0% (the ratio of the plunger cross-sectional area 25 to the syringe cross-sectional area 35 in
As described above, according to the present disclosure, it is possible to provide the filled syringe and the method for storing the resin composition, which can suppress the generation of the void between the resin composition and the inner surface of the syringe.
Number | Date | Country | Kind |
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2017-047609 | Mar 2017 | JP | national |
Filing Document | Filing Date | Country | Kind |
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PCT/JP2018/008653 | 3/6/2018 | WO | 00 |