Claims
- 1. A method for preventing and treating noise or toxin induced sensorineural hearing loss, comprising:(a) selecting subjects experiencing said hearing loss or at risk for acute exposure to noise, toxins, or other stressors causing said hearing loss; and (b) administering to said subjects a pharmaceutically effective amount of a compound selected from the group consisting of: steroids; compounds that are transported into inner ear hair cells and then synthesized by said cells into glurathione; and combinations thereof.
- 2. The method of claim 1 wherein the compound is administered systemically.
- 3. The method of claim 2 wherein the compound is administered orally.
- 4. The method of claim 1 wherein the compound is administered topically.
- 5. The method of claim 4 wherein the compound is administered topically through a catheter to the round window membrane of the inner ear.
- 6. A method for preventing and treating sensorineural hearing lass, comprising:(c) selecting subjects experiencing said hearing loss or at risk for acute exposure to noise, toxins, or other stressors causing said hearing loss; and (d) administering to said subjects a pharmaceutically effective amount of a mixture of compounds selected from the group consisting of: N-L-acetylcysteine; an ester of salicylic acid; a salt of salicylic acid; and any combination thereof.
- 7. A method for preventing and treating non-presbycusis related hearing loss, comprising:(a) selecting subjects experiencing said hearing loss or at risk for acute exposure to noise, toxins, or other stressors causing said hearing loss; and (b) administering to said subjects a pharmaceutically effective amount of aectyl-L-carnitine.
- 8. The method of claim 7, wherein said pharmaceutically effective amount of acetyl-L-carnitine is administered as a mixture including N-L-acetylcysteine.
RELATED APPLICATIONS
This application is a continuation-in-part and divisional of U.S. patent application Ser. No. 09/126,707, filed Jul. 31, 1998 (the entirety of which is incorporated herein by reference for all purposes), which claims benefit of Provisional Application Ser. 60/069,761, filed Dec. 16, 1997.
US Referenced Citations (5)
Provisional Applications (1)
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Number |
Date |
Country |
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60/069761 |
Dec 1997 |
US |
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
09/126707 |
Jul 1998 |
US |
Child |
09/766625 |
|
US |