The present disclosure relates generally to a wound fluid collection canister to be used as part of a wound therapy system. The present disclosure relates more particularly to a printed absorbent in the form of superabsorbent projections for use in the wound fluid collection canisters.
Negative pressure wound therapy (NPWT) is a type of wound therapy that involves applying negative pressure (relative to atmospheric pressure) to a wound site to promote wound healing. Some NPWT systems include a pump which operates to maintain the wound site at negative pressure by removing wound exudate from the wound site. The wound exudate is typically routed to a canister or other container fluidly connected to the pump where the wound exudate is stored until emptied by a user. The canisters may contain an absorbent or solidifier for the purpose of stabilizing the collected wound fluids. In some cases, this may include superabsorbent polymer granules contained within a water dissoluble or cellulose pouch or a gelling agent which causes the collected would exudate to become gel-like in order to prevent sloshing in the canister. However, it is very easy for the pouches to be breached prior to use, which may result in the granules leaking from the pouches. The leaked granules may then cause blockages in various areas of the canister, such as in the conduits, filter chambers, or the collection tubing, which hinders the canisters ability to properly collect wound exudate and other fluids. Additionally, canisters may sometimes be dropped or otherwise damaged, which may also result in the pouches bursting or fracturing. It is therefore desirable to provide a highly robust and stabilized mechanism of absorbing fluid within the canister.
One implementation of the present disclosure is a canister for a wound therapy device. The wound therapy device includes a canister body and a plurality of superabsorbent projections. The canister body is configured to contain wound exudate collected from a wound side. The plurality of superabsorbent projections are fixed to and extend from at least a portion of an interior surface of the canister, and may be formed in a plurality of shapes or patterns comprising circles, squares, hoops/halos, a range of lines, or any combination of said shapes.
Another implementation of the present disclosure is a method of making a canister for fluid collection. The method includes providing a canister body configured to contain wound exudate collected from a wound site. The method further includes preparing a slurry comprising a superabsorbent material. The method further includes applying the slurry onto an interior surface of the canister body in the form of a plurality of superabsorbent projections (nodules, dots, bumps, lumps, islands, protuberances), which may be formed in a plurality of shapes or patterns comprising circles, squares, hoops/halos, a range of lines, or any combination of said shapes.
Those skilled in the art will appreciate that the summary is illustrative only and is not intended to be in any way limiting. Other aspects, inventive features, and advantages of the devices and/or processes described herein, as defined solely by the claims, will become apparent in the detailed description set forth herein and taken in conjunction with the accompanying drawings.
Referring generally to
Advantageously, the superabsorbent projections of the printed absorbent of the canister helps to ensure omni-directional stabilization of fluids within the canister, wherein the canister may be of a variety of different shapes and sizes. In some embodiments, the superabsorbent projections may comprise a plurality of nodules, dots, bumps, lumps, islands, and protuberances extending from the interior surface of the canister. The superabsorbent projections are highly absorptive, and act to absorb wound exudate collected in the canister to prevent the sloshing and spillage of wound exudate from the canister when the canister is moved. Additionally, the superabsorbent projections are configured to remain intact while dissociating from the canister wall such that individual granules are not released into the canister which eliminates the risk of blockages within the canister and potential device failure.
Another advantage provided by the present invention is the increased optimization and customization of the design of the canister. The superabsorbent projections may be printed or otherwise adhered to a variety of locations within the canister, allowing for the customization of where wound exudate will be collected within the canister. Additionally, the methods described herein may be performed on a wide variety of shapes and sizes of canisters, such that the ideal canister may be determined based on factors other than the absorption of wound exudate. Additionally, the present invention provides a low cost solution to the absorption of wound exudate.
Canister with Printed Absorbent
Referring now to
Canister 100 is shown generally to include a first half 102, a second half 104, an interior surface 106 and a plurality of superabsorbent projections 108 extending from an interior surface 106. In some embodiments, superabsorbent projections 108 may extend from the interior surface 106 on both the first half 102 and the second half 104 of canister 100. In other embodiments, superabsorbent projections 108 may extend from the interior surface 106 on one of the first half 102 and the second half 104 of canister 100. In some embodiments, superabsorbent projections 108 may extend from the interior surface 106 primarily near a base of the canister 100, where fluid will drop under gravity. In other embodiments, superabsorbent projections 108 may extend over a majority or the entire interior surface 106, such that the entire inside of the canister 100 is a mobile and omni-directional therapy unit configured to collect fluid in any location on the interior surface 106 of the canister 100. In some embodiments, the interior surface 106 of canister 100 may be molded with a plurality of grooves, in a shape and direction that does not hinder demolding, in order to help retain the printed adhesive and further to increase the relative amount of coating of printed adhesive and help with allowing fluid to access the printed absorbent in order for absorption.
In some embodiments, canister 100 may be used in combination with a therapy device. Therapy devices (not shown) can be configured to provide negative pressure wound therapy by reducing the pressure at a wound. Therapy devices can draw a vacuum at the wound (relative to atmospheric pressure) by removing fluids such as wound exudate. Wound exudate may include fluid that filters from a patient's circulatory system into lesions or areas of inflammation. For example, wound exudate may include water and dissolved solutes such as blood, plasma proteins, white blood cells, platelets, and red blood cells. Other fluids removed from the wound may include instillation fluid previously delivered to the wound. In other embodiments, canister 100 may be used independently of a therapy device, and may collect wound exudate without the use of a negative pressure system.
In various embodiments, collection canister 100 can be formed in a variety of shapes, sizes, and of various materials for the collection of wound exudate. In the embodiment shown in
Superabsorbent Projections
In some embodiments, canister 100 includes a plurality of superabsorbent projections 108 fixed to and extending from the interior surface 106 of canister 100. A top portion of superabsorbent projections 108 extend into an interior cavity of canister 100. In some embodiments, superabsorbent projections 108 comprise a plurality of nodules, dots, bumps, lumps, islands, and lines.
In some embodiments, superabsorbent projections 108 may be formed from or otherwise include a superabsorbent polymer in the form of granules. The superabsorbent polymer may include Luquasorb 1160 or 1161, such as may be commercially available from BASF. The granules may be contained in a water soluble carrier polymer. One example of the water soluble carrier polymer is polyvinylpyrrolidone(PVP). The superabsorbent polymer of the superabsorbent projections 108 and the water soluble polymer may be formed into a slurry or a suspension using an organic solvent. The organic solvent may include propanone or propanol, and may aid in delivery of the superabsorbent projections 108 to the first side 114 of elastic foam layer 106. In some embodiments, to increase the softness of the superabsorbent granules, a plasticizer may be added to the slurry. In one embodiment, the plasticizer may be water. In some embodiments, the slurry to form the superabsorbent projections 108 may have a formulation of 20 parts by mass of PVP, 10 parts by mass of a superabsorbent polymer, 1 part by mass of glycerol, and 100 parts by mass of propanone. In some embodiments, to plasticize the granules, 1 part to 2 parts by mass of water may be added to the slurry mixture. In other embodiments, a water soluble polymer superabsorbent precursor, such as acrylic acid or 2-acrylamido-2-methyl-propanesulfonic acid (AMPS), with suitable UV curing additives, may replace the superabsorbent polymer. Such a precursor may be a relatively low viscosity solution and can be printed interior surface 106 of canister 100 and exposed to UV light to form a soft gel, eliminating the need for a plasticizer. In some embodiments, the water soluble polymer superabsorbent precursor may be similar to that used for preparing hydrogel coatings. In some embodiments, the superabsorbent polymer may be formed from a cross-linked water soluble polymer, based on poly acrylic acids and acrylamides, such as acrylamide and 2acrylamido2methylpropan sulfonic acid (AMPS). In other embodiments, an uncross-linked solution of these polymers may be coated onto the interior surface 106 of canister 100 and then cross linked after application, through a process such as exposure to UV or during the gamma sterilization process of the canister 100. The cross-linking of the polymers after application to the interior surface 106 would allow for clear superabsorbent projections 108, which may permit the level of fluid within superabsorbent projections 108 to be easily observed.
The slurry mixture is applied to interior surface 106 of canister 100 to form superabsorbent projections 108. In some embodiments, the process of applying the slurry mixture to interior surface 106 of the canister 100 may occur prior to the assembly and welding of the canister 100, such that the slurry mixture is applied to both the first half 102 and second half 104 of canister 100 before they are sealed together. In some embodiments, the slurry may be applied to interior surface 106 through standard printing methods, such as silk screen printing, gravure printing, or by x-y plotter printing. In the embodiment shown, the slurry mixture may be applied to both the first half 102 and the second half 104 of canister 100 prior to welding and sealing of canister 100. In other embodiments, canister 100 may comprise a removable lid, such that the slurry mixture may be applied through an opening near the top of the canister 100. In still other embodiments, canister 100 may comprise an opening, such as an opening of which tubing 112 may be inserted into, such that the slurry mixture may be applied through the opening on a side of the canister 100. Superabsorbent projections 108 may be in any non-contiguous shapes such as circles, squares, hexagons, hoops/halos, stars, crosses, a range of lines, or any combination of shapes. Superabsorbent projections 108 may be printed such that they are substantially evenly distributed on the interior surface 106. In other embodiments, superabsorbent projections 108 may be printed in an uneven (e.g. non-uniform, random, etc.) pattern on interior surface 106. In some embodiments, superabsorbent projections 108 are arranged in a non-contiguous manner (i.e. isolated, separated, spaced-apart, non-touching, etc.) so that a region remains between superabsorbent projections 108. In other embodiments, superabsorbent projections 108 may be printed contiguously around various areas of interior surface 106 of the canister 100. In some embodiments, superabsorbent projections 108 may include a flexible plasticized hydrophilic polymer matrix having a substantially continuous structure.
In some embodiments, the slurry mixture may be applied to interior surface 106 in a pattern and particular location within the canister 100 such that the superabsorbent projections 108 will be positioned over the areas in which fluids will collect in the canister. In some embodiments, the slurry mixture is applied to a base of the canister 100, as fluid will collect in the base of the canister 100 due to gravity. In other embodiments, the slurry mixture may be applied over a majority or the entire interior surface 106, such that the entire inside of the canister 100 is a mobile and omni-directional therapy unit configured to collect fluid in any location on the interior surface 106 of the canister 100. In some embodiments, the slurry mixture may be applied in a coating to cover certain areas of the canister 100 to a degree, such as the areas of the canister 100 which have small indentations and nooks.
In some embodiments, in order to aid adhesion of the superabsorbent projections 108 to interior surface 106, interior surface 106 may have a round surface finish, such as a Standex finish, in order to facilitate keying of the two materials to ensure adhesion. In some embodiments, this finish may be incorporated into canister 100 during the injection molding process used to form canister 100, while in other embodiments, the finish may be imparted throughout the canister 100 using a local shot-blasting after injection molding. In still further embodiments, the interior surface 106 of canister 100 may be plasma treated or have a solvent applied in the areas where superabsorbent projections 108 will be applied to aid in bonding with superabsorbent projections 108. In some embodiments, the slurry mixture may further include a fluid-reactive dye (such as a blue dye) that is included into the superabsorbent projections 108. The dye used in superabsorbent projections 108 may act to disguise the collected wound exudate 108, while still allowing for a visual indication as to the level of fluid which has been collected by the superabsorbent projections 108.
Prior to application of the slurry mixture to the interior surface 106, the interior surface 106 may be printed with an adhesive coated film in the areas to which superabsorbent projections 108 may be applied. In some embodiments, the adhesive applied to interior surface 106 is moisture vapor transmitting and/or patterned to allow passage of water vapor therethrough. The adhesive may include a continuous moisture vapor transmitting, pressure-sensitive adhesive layer (e.g., a polyurethane or polyethylene-based pressure sensitive adhesive). In some embodiments, the adhesive may comprise a water soluble/sensitive adhesive. In some embodiments, the adhesive may include one of a viscose, gel-like UV-curing, cyanoacrylate, polyacrylate, or other structural and gap-filling adhesive. In other embodiments, the adhesive may include a polyvinyl alcohol (PVOH) and a copolymer with polyvinyl acetate PVAc). In some embodiments, the PVAc copolymers may provide a higher degree of bonding to the canister 100. The adhesive may be applied in a pattern which reflects the optimum locations for absorbent deposition. In some embodiments, the ratio of PVOH (PVAc, hydrolysis, and molecular mass) may be used to control the water sensitivity of the adhesive and adjust the release rate of the superabsorbent projections 108 from the interior surface 106. Prior to curing but after the application of the adhesive, the canister is exposed to the superabsorbent polymer in the form of granules, which are adhered to the adhesive. Following the adherence of the granules to the adhesive on the interior of canister 106, the canister 100 may be cured. In some embodiments, if each granule of the superabsorbent polymer is bound to the adhesive on the interior surface 106, it will allow for the de-bonding of the superabsorbent projections 108 once they have absorbed wound exudate and other fluids.
Superabsorbent projections 108, as shown in
The construction and arrangement of the systems and methods as shown in the various exemplary embodiments are illustrative only. Although only a few embodiments have been described in detail in this disclosure, many modifications are possible (e.g., variations in sizes, dimensions, structures, shapes and proportions of the various elements, values of parameters, mounting arrangements, use of materials, colors, orientations, etc.). For example, the position of elements can be reversed or otherwise varied and the nature or number of discrete elements or positions can be altered or varied. Accordingly, all such modifications are intended to be included within the scope of the present disclosure. The order or sequence of any process or method steps can be varied or re-sequenced according to alternative embodiments. Other substitutions, modifications, changes, and omissions can be made in the design, operating conditions and arrangement of the exemplary embodiments without departing from the scope of the present disclosure.
This application is a US national phase application under 35 USC § 371 of International Application No. PCT/US2020/016558 filed on Feb. 4, 2020, which claims the benefit of priority to U.S. Provisional Application No. 62/803,031, entitled “PRINTED ABSORBENT FOR USE IN WOUND FLUID COLLECTION CANISTERS” filed on Feb. 8, 2019, which are both hereby incorporated herein by reference in their entireties.
Filing Document | Filing Date | Country | Kind |
---|---|---|---|
PCT/US2020/016558 | 2/4/2020 | WO |
Publishing Document | Publishing Date | Country | Kind |
---|---|---|---|
WO2020/163313 | 8/13/2020 | WO | A |
Number | Name | Date | Kind |
---|---|---|---|
1355846 | Rannells | Oct 1920 | A |
2547758 | Keeling | Apr 1951 | A |
2632443 | Lesher | Mar 1953 | A |
2682873 | Evans et al. | Jul 1954 | A |
2910763 | Lauterbach | Nov 1959 | A |
2969057 | Simmons | Jan 1961 | A |
3066672 | Crosby, Jr. et al. | Dec 1962 | A |
3367332 | Groves | Feb 1968 | A |
3520300 | Flower, Jr. | Jul 1970 | A |
3568675 | Harvey | Mar 1971 | A |
3648692 | Wheeler | Mar 1972 | A |
3682180 | McFarlane | Aug 1972 | A |
3826254 | Mellor | Jul 1974 | A |
4080970 | Miller | Mar 1978 | A |
4096853 | Weigand | Jun 1978 | A |
4139004 | Gonzalez, Jr. | Feb 1979 | A |
4165748 | Johnson | Aug 1979 | A |
4184510 | Murry et al. | Jan 1980 | A |
4233969 | Lock et al. | Nov 1980 | A |
4245630 | Lloyd et al. | Jan 1981 | A |
4256109 | Nichols | Mar 1981 | A |
4261363 | Russo | Apr 1981 | A |
4275721 | Olson | Jun 1981 | A |
4284079 | Adair | Aug 1981 | A |
4297995 | Golub | Nov 1981 | A |
4333468 | Geist | Jun 1982 | A |
4373519 | Errede et al. | Feb 1983 | A |
4382441 | Svedman | May 1983 | A |
4392853 | Muto | Jul 1983 | A |
4392858 | George et al. | Jul 1983 | A |
4419097 | Rowland | Dec 1983 | A |
4465485 | Kashmer et al. | Aug 1984 | A |
4475909 | Eisenberg | Oct 1984 | A |
4480638 | Schmid | Nov 1984 | A |
4525166 | Leclerc | Jun 1985 | A |
4525374 | Vaillancourt | Jun 1985 | A |
4540412 | Van Overloop | Sep 1985 | A |
4543100 | Brodsky | Sep 1985 | A |
4548202 | Duncan | Oct 1985 | A |
4551139 | Plaas et al. | Nov 1985 | A |
4569348 | Hasslinger | Feb 1986 | A |
4605399 | Weston et al. | Aug 1986 | A |
4608041 | Nielsen | Aug 1986 | A |
4640688 | Hauser | Feb 1987 | A |
4655754 | Richmond | Apr 1987 | A |
4664662 | Webster | May 1987 | A |
4710165 | McNeil et al. | Dec 1987 | A |
4733659 | Edenbaum et al. | Mar 1988 | A |
4743232 | Kruger | May 1988 | A |
4758220 | Sundblom et al. | Jul 1988 | A |
4787888 | Fox | Nov 1988 | A |
4826494 | Richmond et al. | May 1989 | A |
4838883 | Matsuura | Jun 1989 | A |
4840187 | Brazier | Jun 1989 | A |
4863449 | Therriault et al. | Sep 1989 | A |
4872450 | Austad | Oct 1989 | A |
4878901 | Sachse | Nov 1989 | A |
4897081 | Poirier et al. | Jan 1990 | A |
4906233 | Moriuchi et al. | Mar 1990 | A |
4906240 | Reed et al. | Mar 1990 | A |
4919654 | Kalt | Apr 1990 | A |
4941882 | Ward et al. | Jul 1990 | A |
4953565 | Tachibana et al. | Sep 1990 | A |
4969880 | Zamierowski | Nov 1990 | A |
4985019 | Michelson | Jan 1991 | A |
5037397 | Kalt et al. | Aug 1991 | A |
5086170 | Luheshi et al. | Feb 1992 | A |
5092858 | Benson et al. | Mar 1992 | A |
5100396 | Zamierowski | Mar 1992 | A |
5134994 | Say | Aug 1992 | A |
5149331 | Ferdman et al. | Sep 1992 | A |
5167613 | Karami et al. | Dec 1992 | A |
5176663 | Svedman et al. | Jan 1993 | A |
5215522 | Page et al. | Jun 1993 | A |
5232453 | Plass et al. | Aug 1993 | A |
5261893 | Zamierowski | Nov 1993 | A |
5278100 | Doan et al. | Jan 1994 | A |
5279550 | Habib et al. | Jan 1994 | A |
5298015 | Komatsuzaki et al. | Mar 1994 | A |
5342376 | Ruff | Aug 1994 | A |
5344415 | DeBusk et al. | Sep 1994 | A |
5358494 | Svedman | Oct 1994 | A |
5437622 | Carion | Aug 1995 | A |
5437651 | Todd et al. | Aug 1995 | A |
5527293 | Zamierowski | Jun 1996 | A |
5549584 | Gross | Aug 1996 | A |
5556375 | Ewall | Sep 1996 | A |
5607388 | Ewall | Mar 1997 | A |
5635196 | Murphy | Jun 1997 | A |
5636643 | Argenta et al. | Jun 1997 | A |
5645081 | Argenta et al. | Jul 1997 | A |
6071267 | Zamierowski | Jun 2000 | A |
6135116 | Vogel et al. | Oct 2000 | A |
6241747 | Ruff | Jun 2001 | B1 |
6287316 | Agarwal et al. | Sep 2001 | B1 |
6345623 | Heaton et al. | Feb 2002 | B1 |
6488643 | Tumey et al. | Dec 2002 | B1 |
6493568 | Bell et al. | Dec 2002 | B1 |
6553998 | Heaton et al. | Apr 2003 | B2 |
6814079 | Heaton et al. | Nov 2004 | B2 |
8216198 | Heagle et al. | Jul 2012 | B2 |
9061095 | Adie | Jun 2015 | B2 |
20020077661 | Saadat | Jun 2002 | A1 |
20020115951 | Norstrem et al. | Aug 2002 | A1 |
20020120185 | Johnson | Aug 2002 | A1 |
20020143286 | Tumey | Oct 2002 | A1 |
20030120231 | Wang et al. | Jun 2003 | A1 |
20030205318 | Ko et al. | Nov 2003 | A1 |
20080032014 | Frenz | Feb 2008 | A1 |
20100286638 | Malhi | Nov 2010 | A1 |
20120024722 | Chen | Feb 2012 | A1 |
20120061261 | Hsu | Mar 2012 | A1 |
20130066301 | Locke et al. | Mar 2013 | A1 |
20180264721 | Iida | Sep 2018 | A1 |
20190001030 | Braga | Jan 2019 | A1 |
Number | Date | Country |
---|---|---|
550575 | Mar 1986 | AU |
745271 | Mar 2002 | AU |
755496 | Dec 2002 | AU |
2005436 | Jun 1990 | CA |
105920687 | May 2018 | CN |
26 40 413 | Mar 1978 | DE |
43 06 478 | Sep 1994 | DE |
29 504 378 | Sep 1995 | DE |
10 2010 060 543 | Apr 2012 | DE |
0100148 | Feb 1984 | EP |
0117632 | Sep 1984 | EP |
0161865 | Nov 1985 | EP |
0358302 | Mar 1990 | EP |
1018967 | Jul 2000 | EP |
692578 | Jun 1953 | GB |
2 195 255 | Apr 1988 | GB |
2 197 789 | Jun 1988 | GB |
2 220 357 | Jan 1990 | GB |
2 235 877 | Mar 1991 | GB |
2 329 127 | Mar 1999 | GB |
2 333 965 | Aug 1999 | GB |
4129536 | Aug 2008 | JP |
71559 | Apr 2002 | SG |
8002182 | Oct 1980 | WO |
8704626 | Aug 1987 | WO |
90010424 | Sep 1990 | WO |
93009727 | May 1993 | WO |
94020041 | Sep 1994 | WO |
9605873 | Feb 1996 | WO |
9718007 | May 1997 | WO |
9913793 | Mar 1999 | WO |
Entry |
---|
Louis C. Argenta, MD and Michael J. Morykwas, PhD; Vacuum-Assisted Closure: A New Method for Wound Control and Treatment: Clinical Experience; Annals of Plastic Surgery; vol. 38, No. 6, Jun. 1997; pp. 563-576. |
Susan Mendez-Eatmen, RN; “When wounds Won't Heal” RN Jan. 1998, vol. 61 (1); Medical Economics Company, Inc., Montvale, NJ, USA; pp. 20-24. |
James H. Blackburn II, MD et al.: Negative-Pressure Dressings as a Bolster for Skin Grafts; Annals of Plastic Surgery, vol. 40, No. 5, May 1998, pp. 453-457; Lippincott Williams & Wilkins, Inc., Philidelphia, PA, USA. |
John Masters; “Reliable, Inexpensive and Simple Suction Dressings”; Letter to the Editor, British Journal of Plastic Surgery, 1998, vol. 51 (3), p. 267; Elsevier Science/The British Association of Plastic Surgeons, UK. |
S.E. Greer, et al. “The Use of Subatmospheric Pressure Dressing Therapy to Close Lymphocutaneous Fistulas of the Groin” British Journal of Plastic Surgery (2000), 53, pp. 484-487. |
George V. Letsou, MD., et al.; “Stimulation of Adenylate Cyclase Activity in Cultured Endothelial Cells Subjected to Cyclic Stretch”; Journal of Cardiovascular Surgery, 31, 1990, pp. 634-639. |
Orringer, Jay, et al.; “Management of Wounds in Patients with Complex Enterocutaneous Fistulas”; Surgery, Gynecology & Obstetrics, Jul. 1987, vol. 165, pp. 79-80. |
International Search Report for PCT International Application PCT/GB95/01983; dated Nov. 23, 1995. |
PCT International Search Report for PCT International Application PCT/GB98/02713; dated Jan. 8, 1999. |
PCT Written Opinion; PCT International Application PCT/GB98/02713; dated Jun. 8, 1999. |
PCT International Examination and Search Report, PCT International Application PCT/GB96/02802; dated Jan. 15, 1998 & Apr. 29, 1997. |
PCT Written Opinion, PCT International Application PCT/GB96/02802; dated Sep. 3, 1997. |
Dattilo, Philip P., Jr., et al.; “Medical Textiles: Application of an Absorbable Barbed Bi-directional Surgical Suture”; Journal of Textile and Apparel, Technology and Management, vol. 2, Issue 2, Spring 2002, pp. 1-5. |
Kostyuchenok, B.M., et al.; “Vacuum Treatment in the Surgical Management of Purulent Wounds”; Vestnik Khirurgi, Sep. 1986, pp. 18-21 and 6 page English translation thereof. |
Davydov, Yu. A., et al; “Vacuum Therapy in the Treatment of Purulent Lactation Mastitis”; Vestnik Khirurgi, May 14, 1986, pp. 66-70, and 9 page English translation thereof. |
Yusupov. Yu.N., et al; “Active Wound Drainage”, Vestnki Khirurgi, vol. 138, Issue 4, 1987, and 7 page English translation thereof. |
Davydov, Yu.A., et al; “Bacteriological and Cytological Assessment of Vacuum Therapy for Purulent Wounds”; Vestnik Khirugi, Oct. 1988, pp. 48-52, and 8 page English translation thereof. |
Davydov, Yu.A., et al; “Concepts for the Clinical-Biological Management of the Wound Process in the Treatment of Purulent Wounds by Means of Vacuum Therapy”; Vestnik Khirurgi, Jul. 7, 1980, pp. 132-136, and 8 page English translation thereof. |
Chariker, Mark E., M.D., et al; “Effective Management of incisional and cutaneous fistulae with closed suction wound drainage”; Contemporary Surgery, vol. 34, Jun. 1989, pp. 59-63. |
Egnell Minor, Instruction Book, First Edition, 300 7502, Feb. 1975, pp. 24. |
Egnell Minor: Addition to the Users Manual Concerning Overflow Protection—Concerns all Egnell Pumps, Feb. 3, 1983, pp. 2. |
Svedman, P.: “Irrigation Treatment of Leg Ulcers”, The Lancet, Sep. 3, 1983, pp. 532-534. |
Chinn, Steven D. et al.: “Closed Wound Suction Drainage”, The Journal of Foot Surgery, vol. 24, No. 1, 1985, pp. 76-81. |
Arnljots, Bjom et al.: “Irrigation Treatment in Split-Thickness Skin Grafting of Intractable Leg Ulcers”, Scand J. Plast Reconstr. Surg., No. 19, 1985, pp. 211-213. |
Svedman, P.: “A Dressing Allowing Continuous Treatment of a Biosurface”, IRCS Medical Science: Biomedical Technology, Clinical Medicine, Surgery and Transplantation, vol. 7, 1979, p. 221. |
Svedman, P. et al: “A Dressing System Providing Fluid Supply and Suction Drainage Used for Continuous of Intermittent Irrigation”, Annals of Plastic Surgery, vol. 17, No. 2, Aug. 1986, pp. 125-133. |
N.A. Bagautdinov, “Variant of External Vacuum Aspiration in the Treatment of Purulent Diseases of Soft Tissues,” Current Problems in Modern Clinical Surgery: Interdepartmental Collection, edited by V. Ye Volkov et al. (Chuvashia State University, Cheboksary, U.S.S.R. 1986); pp. 94-96 (copy and certified translation). |
K.F. Jeter, T.E. Tintle, and M. Chariker, “Managing Draining Wounds and Fistulae: New and Established Methods,” Chronic Wound Care, edited by D. Krasner (Health Management Publications, Inc., King of Prussia, PA 1990), pp. 240-246. |
G. {hacek over (Z)}ivadinovi?, V. ?uki?, {hacek over (Z)}. Maksimovi?, ?. Radak, and p. Pe{hacek over (s)}ka, “Vacuum Therapy in the Treatment of Peripheral Blood Vessels,” Timok Medical Journal 11 (1986), pp. 161-164 (copy and certified translation). |
F.E. Johnson, “An Improved Technique for Skin Graft Placement Using a Suction Drain,” Surgery, Gynecology, and Obstetrics 159 (1984), pp. 584-585. |
A.A. Safronov, Dissertation Abstract, Vacuum Therapy of Trophic Ulcers of the Lower Leg with Simultaneous Autoplasty of the Skin (Central Scientific Research Institute of Traumatology and Orthopedics, Moscow, U.S.S.R. 1967) (copy and certified translation). |
M. Schein, R. Saadia, J.R. Jamieson, and G.A.G. Decker, “The ‘Sandwich Technique’ in the Management of the Open Abdomen,” British Journal of Surgery 73 (1986), pp. 369-370. |
D.E. Tribble, An Improved Sump Drain-Irrigation Device of Simple Construction, Archives of Surgery 105 (1972) pp. 511-513. |
M.J. Morykwas, L.C. Argenta, E.I. Shelton-Brown, and W. McGuirt, “Vacuum-Assisted Closure: A New Method for Wound Control and Treatment: Animal Studies and Basic Foundation,” Annals of Plastic Surgery 38 (1997), pp. 553-562 (Morykwas I). |
C.E. Tennants, “The Use of Hypermia in the Postoperative Treatment of Lesions of the Extremities and Thorax,”Journal of the American Medical Association 64 (1915), pp. 1548-1549. |
Selections from W. Meyer and V. Schmieden, Bier's Hyperemic Treatment in Surgery, Medicine, and the Specialties: A Manual of Its Practical Application, (W.B. Saunders Co., Philadelphia, PA 1909), pp. 17-25, 44-64, 90-96, 167-170, and 210-211. |
V.A. Solovev et al., Guidelines, The Method of Treatment of Immature External Fistulas in the Upper Gastrointestinal Tract, editor-in-chief Prov. V.I. Parahonyak (S.M. Kirov Gorky State Medical Institute, Gorky, U.S.S.R. 1987) (“Solovev Guidelines”). |
V.A. Kuznetsov & N.a. Bagautdinov, “Vacuum and Vacuum-Sorption Treatment of Open Septic Wounds,” in II All-Union Conference on Wounds and Wound Infections: Presentation Abstracts, edited by B.M. Kostyuchenok et al. (Moscow, U.S.S.R. Oct. 28-29, 1986) pp. 91-92 (“Bagautdinov II”). |
V.A. Solovev, Dissertation Abstract, Treatment and Prevention of Suture Failures after Gastric Resection (S.M. Kirov Gorky State Medical Institute, Gorky, U.S.S.R. 1988) (“Solovev Abstract”). |
V.A.C. @ Therapy Clinical Guidelines: A Reference Source for Clinicians; Jul. 2007. |
International Search Report and Written Opinion on International Patent Application No. PCT/US2020/016558 dated May 7, 2020 (10 pages). |
Number | Date | Country | |
---|---|---|---|
20220072218 A1 | Mar 2022 | US |
Number | Date | Country | |
---|---|---|---|
62803031 | Feb 2019 | US |