Claims
- 1. A compound of the structural formula: ##STR49## wherein R.sup.2 is independently selected from hydrogen, linear or branched C.sub.1 -C.sub.3 alkyl, which can be substituted with fluoro, hydroxy, or protected hydroxy, R.sup.3 is hydrogen or a protecting group, X is sulfur or selenium, Q is hydroxymethyl, carboxy or C.sub.1 -C.sub.4 alkoxycarbonyl, and R.sup.1 is C.sub.1 -C.sub.4 alkyl, C.sub.6 -C.sub.10 aryl, and pyridyl which can be substituted with C.sub.1 -C.sub.4 alkyl, alkoxy and nitro.
- 2. The compound of claim 1 wherein said R.sup.2 is independently selected from H, CH.sub.3 --, CH.sub.3 CH.sub.2 --, (CH.sub.3).sub.2 CH--, HOCH.sub.2 --, CH.sub.3 CHOH--, CH.sub.3 CH.sub.2 CHOH--, (CH.sub.3).sub.2 COH--, FCH.sub.2 CHOH--, FCH.sub.2 --, F.sub.2 CH--, F.sub.3 C--, CH.sub.3 CHF--, CH.sub.3 CF.sub.2 -- or (CH.sub.3).sub.2 CF--.
- 3. A compound of the structural formula: ##STR50## wherein R.sup.3 and R.sup.4 are independently hydrogen or a blocking group, R.sup.1 is C.sub.1 -C.sub.4 alkyl, C.sub.6 -C.sub.10 aryl or pyridyl which can be substituted with C.sub.1 -C.sub.4 alkyl, alkoxy, and nitro, X is sulfur or selenium, Q is hydroxymethyl, carboxy or C.sub.1 -C.sub.4 alkoxycarbonyl.
- 4. The compound of claim 3 of the structural formula: ##STR51## wherein R.sup.5 is H or C.sub.1 -C.sub.4 alkyl.
- 5. The compound of claim 4 wherein R.sup.5 is methyl.
- 6. The compound of claim 3 of the structural formula: ##STR52##
Parent Case Info
This is a continuation of application Ser. No. 157,165, filed Feb. 11, 1988 now abandoned, which is a continuation of application Ser. No. 059,143, filed Jun. 5, 1987, now abandoned, which was a continuation of application Ser. No. 008,050, filed Jan. 15, 1987, now abandoned, which in turn was a continuation of application, Ser. No. 703,052, filed Feb. 19, 1985, now abandoned.
US Referenced Citations (5)
Non-Patent Literature Citations (8)
Entry |
Kametani et al., Heterocycles, 19, 1023 (1982). |
Greengrass, Tet. Letters 22, 1161 (1981). |
Prasad, Tet. Letters 23, 1247 (1982). |
Tetrahedron Letters, vol. 23, No. 33, 1982, pp. 3379-3382, Yanagisawa et al. |
Tetrahedron Letters, vol. 24, No. 4, 1983, pp. 335-338, Phillips et al. |
Shionogi Res. Lab. Chem. Abstracts, vol. 97, No. 3, 23504j, 1982. |
Heterocycles, 1984, vol. 21, pp. 29-40, Shih et al. |
Reagents for Organic Synthesis, vol. 1, pp. 723-729 by S. L. Feiser. |
Continuations (4)
|
Number |
Date |
Country |
Parent |
157165 |
Feb 1988 |
|
Parent |
59143 |
Jun 1987 |
|
Parent |
8050 |
Jan 1987 |
|
Parent |
703052 |
Feb 1985 |
|