Claims
- 1. A process for the preparation of 4-aryl-piperidines of structure (1): in which R is hydrogen or an alkyl, aralkyl, aryl, acyl, alkoxycarbonyl, arylalkoxycarbonyl, aryloxycarbonyl group; and Z′ is a 3,4-methylenedioxyphenyl group; which process comprises converting a compound of structure (4c) or (4d): in which R is hydrogen or an alkyl, aralkyl, aryl, acyl, alkoxycarbonyl, arylalkoxycarbonyl, aryloxycarbonyl group; and X is hydrogen or from one to four reducible groups; into a compound of structure (1).
Priority Claims (2)
Number |
Date |
Country |
Kind |
9711095 |
May 1997 |
GB |
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9714875 |
Jul 1997 |
GB |
|
Parent Case Info
This is a continuation of application Ser. No. 09/688,423 filed Oct. 16, 2000, now abandoned, which is a continuation of application Ser. No. 09/087,632, filed May 29, 1998, now U.S. Pat. No. 6,489,347.
US Referenced Citations (16)
Foreign Referenced Citations (9)
Number |
Date |
Country |
0 190 496 |
Aug 1986 |
EP |
0 300 617 |
Jan 1989 |
EP |
0 374 674 |
Jun 1990 |
EP |
0 802 185 |
Oct 1997 |
EP |
0 812 827 |
Dec 1997 |
EP |
2121685 |
Dec 1998 |
ES |
WO 9636636 |
Nov 1996 |
WO |
WO 9845263 |
Oct 1998 |
WO |
WO 0026187 |
May 2000 |
WO |
Non-Patent Literature Citations (8)
Entry |
Miscovic et al., J. Chem. Soc., Perk Trans. 1, No. 16, pp. 2041-2050 (1996). |
Carey, Organic Chemistry, McGraw-Hill Book Co., p. 566 (1987). |
Chemical Abstracts 127:358789 (1997). |
Chemical Abstracts 121:57525 (1992). |
Chemical Abstracts 118:254964 (1992). |
Chemical Abstracts 129:156928 (1996). |
Koelsch, J. Am. Chem. Soc., vol. 65, pp. 2459-2460 (1943). |
Peters et al., Chemical Abstract 132:321802. |
Continuations (2)
|
Number |
Date |
Country |
Parent |
09/688423 |
Oct 2000 |
US |
Child |
10/138553 |
|
US |
Parent |
09/087632 |
May 1998 |
US |
Child |
09/688423 |
|
US |