Banerjee et al., “Derivatives of 3,4-Dihydroxyphenylalanine for Peptide Synthesis” J. Org. Chem. (1976) 41(18):3056-3058 (Exhibit 12). |
Bodor et al., “Improved Delivery Through Biological Membranes. 4. Prodrugs of L-DOPA” Journal of Medicinal Chemistry (1977) 20(11): 1435-1445 (Exhibit 13). |
Cooper et al., “L-DOPA Methyl Ester—A Candidate for Chronic Systemic Delivery of L-DOPA in Parkinson's Disease” Clin. Neuropharmacol. (1984) 7:(1) 89-98 (Exhibit 14). |
Cooper et al., “L-Dopa Esters as Potential Prodrugs: Behavioural Activity in Experimental Models of Parkinson's Disease” J. Pharm Pharmacol (Aug. 1987) 39(8): 627-635 (Exhibit 15). |
El-Naggar et al., “Synthesis of Some Dipeptides Containing 2-Aminobutyric Acid, 3,4-Dihydroxyphenylalanine, Urea and Thiourea Derivatives” Polish Journal of Chemistry (1978) 52:1809-1814 (Exhibit 16). |
Fix et al., “Short-Chain Alkyl Esters of L-DOPA as Prodrugs for Rectal Absorption” Pharm. Res. (1989) 6(6): 501-505 (Exhibit 17). |
Juncos et al., “Levodopa Methyl Ester Treatment of Parkinson's Disease” Neurology (1987) 37 : 1242-1245 (Exhibit 18). |
Lai et al., New Compounds: Synthesis of Alkyl Esters of D,L-DOPA, J. Phar. Sci. (1973) 62: 510-511 (Exhibit 19). |
Lou et al., “Direct Enantiomer Separation of Phenylalanine, DOPA and Their Intermediates by Supercritical Fluid Chromatography” Journal of Chromatography (1992) 605: 103-107 (Exhibit 20). |
Marrel et al., “L-DOPA Esters as Potential Prodrugs” Eur. J. Med. Chem. (1985) 20(5): 459-465 (Exhibit 21). |
Tomiuchi et al., “Enzymatic Reactions in Aqueous-Organic Media. XVII. Optical Resolution of Amino Acid Esters by Enzymatic Hydrolsis in Organic Solvents” Bull. Chem. Soc. Jpn.(1992) 65: 2599-2603 (Exhibit 22) and. |
Venter et al., “Synthesis Phenylpropanolamine Derivatives as Potentitial β-Adrenergic Agents” S. Afr. Tydskr. Chem (1978) 31(4): 135-137 (Exhibit 23). |