Claims
- 1. A process for the preparation of microspheroidal particles of a polymer in injectable dosage form which comprises, dissolving the polymer in a volatile, water-immiscible solvent, mixing the polymer-solvent system with an aqueous solution containing only sodium oleate or potassium oleate as an emulsifier to form an oil-in-water emulsion, removing the solvent to form discrete microspheroidal particles of essentially only polymer, and isolating the discrete microspheroidal particles free of agglomerates from the resulting aqueous solution.
- 2. A process for the preparation of microspheroidal particles of a drug in injectable dosage form which comprises dissolving the drug in a volatile, water-immiscible solvent mixing the drug-solvent system with an aqueous solution containing only sodium oleate or potassium oleate as an emulsifier to form an oil-in-water emulsion, removing the solvent to form discrete microspheroidal particles of essentially only drug, and isolating the discrete microspheroidal particles free of agglomerates from the resulting aqueous solution.
Parent Case Info
This application is a continuation of application Ser. No. 723,949 filed Apr. 16, 1985 and now abandoned, which in turn is a continuation of application Ser. No. 472,888 filed Mar. 8, 1983 now abandoned, which in turn is a continuation of application Ser. No. 159,148 filed June 13, 1980 now U.S. Pat. No. 4,384,975.
US Referenced Citations (3)
Foreign Referenced Citations (1)
Number |
Date |
Country |
461649 |
Feb 1937 |
GBX |
Continuations (3)
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Number |
Date |
Country |
Parent |
723949 |
Apr 1985 |
|
Parent |
472888 |
Mar 1983 |
|
Parent |
159148 |
Jun 1980 |
|