Claims
- 1. A process for preparing a compound of the formula ##STR9## wherein D is selected from the group consisting of ##STR10## R.sub.1 is selected from the group consisting of hydrogen, halogen, nitro and trifluoromethyl; R.sub.2 is selected from the group consisting of hydrogen and lower alkyl; and R.sub.3 is selected from the group consisting of hydrogen and halogen
- which comprises reacting a compound of the formula ##STR11## wherein D, R.sub.1 and R.sub.2 are as above and X is selected from the group consisting of chlorine, bromine and iodine
- with hexamethylenetetramine in the presence of ammonia and an inert organic solvent.
- 2. A process as defined in claim 1 wherein the reaction is effected under pressure.
- 3. A process as defined in claim 1 wherein the ammonia is provided to the reaction zone in such quantities as to saturate the inert organic solvent being employed.
- 4. A process as defined in claim 1 wherein D is the grouping ##STR12## R.sub.1 is halogen or nitro and R.sub.2 is hydrogen or methyl.
- 5. A process as defined in claim 4 wherein R.sub.1 is chlorine, bromine or nitro, R.sub.2 is hydrogen or methyl, and R.sub.3 is hydrogen, chlorine or fluorine.
- 6. A process as defined in claim 5 wherein the ammonia is provided to the reaction zone in such quantities as to saturate the inert solvent being employed.
- 7. A process as defined in claim 6 wherein R.sub.1 is nitro.
- 8. A process as defined in claim 6 wherein R.sub.1 is chlorine.
- 9. A process as defined in claim 1 wherein R.sub.1 is chlorine, R.sub.2 is hydrogen and D is the grouping ##STR13## wherein R.sub.3 is hydrogen.
- 10. A process as defined in claim 9 wherein the ammonia is provided to the reaction zone in such quantities as to saturate the inert organic solvent being employed.
- 11. A process as in claim 10 wherein an aqueous inert organic solvent is utilized.
- 12. A process for preparing a compound of the formula ##STR14## wherein D is selected from the group consisting of ##STR15## R.sub.1 is selected from the group consisting of hydrogen, halogen, nitro and trifluoromethyl; R.sub.2 is selected from the group consisting of hydrogen and lower alkyl; and R.sub.3 is selected from the group consisting of hydrogen and halogen
- which comprises reacting a compound of the formula ##STR16## wherein D, R.sub.1 and R.sub.2 are as above and X is selected from the group consisting of chlorine, bromine and iodine
- with formaldehyde in the presence of ammonia and an inert organic solvent.
- 13. A process as in claim 12 wherein X is chlorine.
- 14. A process as defined in claim 13 wherein D is the grouping ##STR17## R.sub.1 is halogen or nitro and R.sub.2 is hydrogen or methyl.
- 15. A process as defined in claim 14 wherein R.sub.1 is chlorine, bromine or nitro, R.sub.3 is hydrogen or methyl, and R.sub.4 is hydrogen, chlorine or fluorine.
- 16. A process as defined in claim 15 wherein R.sub.1 is chlorine.
Parent Case Info
This is a continuation of application Ser. No. 359,814 filed May 14, 1973, which in turn is a continuation-in-part of application Ser. No. 282,217 filed Aug. 21, 1972. Both applications are now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
3886141 |
Chase |
May 1975 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
7,001,765 |
Apr 1971 |
NL |
Non-Patent Literature Citations (2)
Entry |
Blazevic et al. I. "J. Het. Chem." vol. 7 pp. 1173-1174 (1970). |
Blazevic et al. II "J. Het. Chem." vol. 9 pp. 531-537 (1972). |
Continuations (1)
|
Number |
Date |
Country |
Parent |
359814 |
May 1973 |
|
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
282217 |
Aug 1972 |
|