Claims
- 1. A process for preparing benzophenone derivatives having the general formula
- wherein each of X and Y is a substituent selected from the group consisting of a halogen; a nitro group; an alkyl group; an amino group substituted with two substituents selected from the group consisting of a saturated C.sub.1-4 alkyl group, an allyl group, a propargyl group, a phenyl group, a tolyl group and a benzyl group; a morpholino group; a pyrimidino group; a pyrrolidino group; and a C.sub.1-2 alkoxy group, each of m and n is 0 or an integer from 1 to 2, or XM ##STR67## is a moiety selected from the group consisting of a juloidine moiety or a 1-butyl, 1,2,3,4-tetrahydroquinoline moiety which comprises dissolving a 3-phenylphthalide derivative having the general formula ##STR68## wherein X, Y, m and n are the same as described hereinbefore, into an aqueous solution of alkali salt and oxidizing said dispersed 3-phenylphthalide derivative with at least one oxidizing agent, said alkali salt being in at least an equimolar amount with respect to said 3-phenylphthalide derivative.
- 2. A process for preparing benzophenone derivative as defined in claim 1, wherein said 3-phenylphthalide derivative having the general formula (II) has Y at the 6 position.
- 3. A process for preparing a benzophenone derivative as defined in claim 2, wherein said Y is an amino group substituted with two substituents selected from the group consisting of a saturated C.sub.1-4 alkyl group, an allyl group, a propargyl group, a phenyl group, a tolyl group and a benzyl group; a morpholino group; a pyrimido group or a pyrrolidino group.
- 4. A process for preparing benzophenone derivative as defined in claim 1, wherein said oxidizing agent is an organic nitro compound.
- 5. A process for preparing benzophenone derivative as defined in claim 4, wherein said organic nitro compound is nitrobenzenesulfonate.
- 6. A process for preparing benzophenone derivative as defined in claim 1, wherein said alkali salt is selected from hydroxides of alkali metal.
- 7. A process for preparing benzophenone derivative as defined in claim 6, wherein said hydroxide of alkali metal is sodium hydroxide or potassium hydroxide.
- 8. A process for preparing benzophenone derivative as defined in claim 1, wherein the oxidative reaction of said 3-phenylphthalide derivative is carried out at a temperature within the range of 0.degree. to 200.degree. C.
- 9. A process for preparing benzophenone derivatives as defined in claim 1, wherein said 3-phenylphthalide derivative is 3-(p-dimethylaminophenyl)-6-dimethylaminophthalide.
- 10. A process for preparing benzophenone derivatives as defined in claim 1, wherein said 3-phenylphthalide derivative is 3-(p-dimethylaminophenyl)-phthalide.
- 11. A process for preparing benzophenone derivatives as defined in claim 1, wherein said 3-phenylphthalide derivative is 3-p-(N-benzyl-N-ethyl)aminophenyl-phthalide.
- 12. A process for preparing benzophenone derivatives as defined in claim 1, wherein said 3-phenylphthalide derivative is 3-(o-methoxyphenyl)-6-dimethylaminophthalide.
- 13. A process for preparing benzophenone derivatives as defined in claim 1, wherein said 3-phenylphthalide derivative is 3-(p-methoxyphenyl)-6-dimethylaminophthalide.
- 14. A process for preparing benzophenone derivatives as defined in claim 1, wherein said 3-phenylphthalide derivative is 3-(p-methylphenyl)-6-dimethylaminophthalide.
- 15. A process for preparing benzophenone derivatives as defined in claim 1, wherein said 3-phenylphthalide derivative is 3-(3,4-dimethoxyphenyl)-6-dimethylaminophthalide.
- 16. A process for preparing benzophenone derivatives as defined in claim 1, wherein said 3-phenylphthalide derivative is 3-(2-methyl-4-N,N-dimethylamino-phenyl)-phthalide.
- 17. A process for preparing benzophenone derivatives as defined in claim 1, wherein said 3-phenylphthalide derivative is 3-(4-N-methyl-N-ethylamino-phenyl)-phthalide.
Priority Claims (1)
Number |
Date |
Country |
Kind |
51-23912 |
Mar 1976 |
JPX |
|
Parent Case Info
This is a continuation of application Ser. No. 772,124 filed Feb. 25, 1977, now abandoned.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
2753373 |
Hutchings et al. |
Jul 1955 |
|
3634500 |
McCormick et al. |
Jan 1972 |
|
4057573 |
Haas et al. |
Nov 1977 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
937378 |
Sep 1963 |
GBX |
Non-Patent Literature Citations (1)
Entry |
Grabe et al., Berichte 21, pp. 2003-2005, (1888). |
Continuations (1)
|
Number |
Date |
Country |
Parent |
772124 |
Feb 1977 |
|