Claims
- 1. A process for the preparation of highly pure cefuroxime axetil containing less than 5% m/m impurities and in predominantly amorphous form which comprises recovering cefuroxime axetil from a solution thereof which contains an organic solvent selected from the group consisting of ketones, alcohols, acetonitrile, tetrahydrofuran, dioxan, esters, chlorinated solvents, homogeneous mixtures of at least two of the aforesaid solvents and homogeneous mixtures of at least one of the aforementioned solvents and water, by solvent precipitation.
- 2. The process of claim 1 wherein the concentration of cefuroxime axetil in the solution prior to recovery is at least 1% m/m.
- 3. The process of claim 1 wherein the concentration of cefuroxime axetil in the solution prior to recovery is at least 10% m/m.
Priority Claims (1)
Number |
Date |
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Kind |
8222019 |
Jul 1982 |
GBX |
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Parent Case Info
This application is a division of application Ser. No. 938,140, filed 12-4-86, now U.S. Pat. No. 4,720,833, issued April 11, 1989, which is a continuation of Ser. No. 781,505, filed 9-30-85, now abandoned; which is a continuation of Ser. No. 711,559, filed 3-14-85, now abandoned; which is a continuation of Ser. No. 635,797, filed 7-30-84, now abandoned; which is a continuation of Ser. No. 518,671, filed 7-29-83, now abandoned.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
4002748 |
Bornstein et al. |
Jan 1977 |
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4267230 |
Gregson et al. |
May 1981 |
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4562181 |
Crisp et al. |
Dec 1987 |
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Divisions (1)
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Number |
Date |
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Parent |
938140 |
Dec 1986 |
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Continuations (4)
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Number |
Date |
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Parent |
781505 |
Sep 1985 |
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Parent |
711559 |
Mar 1985 |
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Parent |
635797 |
Jul 1984 |
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Parent |
518671 |
Jul 1983 |
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