Claims
- 1. A process for preparing 1-(pyridinyl)-1,1-dialkoxy-1-aminoethane derivatives of the formula (I)
- 2. The process as claimed in claim 1, wherein the pyridine radical is substituted in the 3-position.
- 3. The process as claimed in claim 1, wherein R1 and R2 are each (C1-C6)-alkyl.
- 4. The process as claimed in claim 1, wherein, the hydroxylammonium compound in process step (a) is selected from the group consisting of hydroxylamine, hydroxylammonium chloride and hydroxylammonium sulfate.
- 5. The process as claimed in claim 1, wherein, in process step (a), Mn+ is Li+, Na+, K+ or Ca2+.
- 6. The process as claimed in claim 1, wherein, in process step (a), the inorganic base is selected from the group consisting of lithium hydroxide, sodium hydroxide, sodium carbonate, sodium hydrogencarbonate, potassium hydroxide, potassium carbonate and calcium hydroxide.
- 7. The process as claimed in claim 1, wherein, in process step (b), the leaving group Y is Cl.
- 8. The process as claimed in claim 1, wherein, in process step (b), the phase transfer catalyst is a quaternary ammonium salt of the formula (XII) or a phosphonium salt of the formula (XIII)
- 9. The process as claimed in claim 1, wherein, in process step (c), the alkali or alkaline earth metal alkoxide, and alkali or alkaline earth metal hydroxide are selected from the group consisting of lithium hydroxide, lithium methoxide, lithium ethoxide, sodium hydroxide, sodium methoxide, sodium ethoxide, potassium hydroxide, potassium methoxide, potassium ethoxide, cesium hydroxide, cesium methoxide and cesium ethoxide.
- 10. The process as claimed in claim 1, wherein, in process step (c), the acetylpyridine tosyl oxime of the formula (XI) is used without prior drying.
- 11. A process for preparing an acetylpyridine oxime metal salt of the formula (IX)
- 12. The process as claimed in claim 11, wherein the pyridine radical is substituted in the 3-position.
- 13. The process as claimed in claim 11, wherein M is Li+, Na+, K+ or Ca2+.
- 14. The process as claimed claim 11, wherein the inorganic base is lithium hydroxide, sodium hydroxide, sodium carbonate, sodium hydrogencarbonate, potassium hydroxide, potassium carbonate or calcium hydroxide.
- 15. The process as claimed in claim 11, which is conducted continuously.
- 16. A process for preparing the compound of the formula (XI)
- 17. The process as claimed in claim 16, which proceeds with the use of one or more phase transfer catalysts, and wherein the phase transfer catalyst is a quaternary ammonium salt of the formula (XII) or a phosphonium salt of the formula (XIII)
- 18. The process as claimed in claim 16, wherein the pyridine radical is substituted in the 3-position.
Priority Claims (1)
Number |
Date |
Country |
Kind |
10305391.3 |
Feb 2003 |
DE |
|
Parent Case Info
[0001] This application claims the benefit of priority of German Patent Application No. 10305391.3, filed Feb. 11, 2003 and the benefit of U.S. Provisional Application No. 60/482,295 filed Jun. 25, 2003.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60482295 |
Jun 2003 |
US |