Claims
- 1. A process for preparing a hydrazide compound of the formula ##STR10## comprising (a) reacting an amine of the formula ##STR11## with an oxamate of the formula ##STR12## to form an oxamide of the formula ##STR13## (b) reacting the oxamide with hydrazine or hydrazine hydrate, where R is hydrogen, oxy, hydroxy, unsubstituted aliphatic of 1 to 20 carbons, unsubstituted araliphatic of 7 to 12 carbons, 2-cyanoethyl, unsubstituted hydroxyaliphatic of 1 to 6 carbons, or a polyalkylene oxide group of 4 to 30 carbons;
- R.sup.1 is hydrogen or lower alkyl of 1 to 4 carbons;
- R.sup.2 is hydrogen, unsubstituted aliphatic of 1 to 10 carbons, unsubstituted alicyclic of 5 to 12 carbons, unsubstituted araliphatic of 7 to 12 carbons, unsubstituted aryl of 6 to 12 carbons, 2-cyanoethyl or a radical of the formula ##STR14## and R.sup.5 is lower alkyl of 1 to 6 carbons or phenyl.
- 2. The process according to claim 1, where reaction steps (a) and (b) are conducted in an alcoholic or glycolic solvent; and
- (c) the hydrazide compound is isolated by crystallization from the solvent or by evaporation of the solvent.
- 3. The process according to claim 1, where
- R is hydrogen, oxy, hydroxy, alkyl of 1 to 10 carbons, alkenyl of 3 to 5 carbons, alkynyl of 3 to 5 carbons, aralkyl of 7 to 9 carbons, or hydroxyalkyl of 1 to 6 carbons;
- R.sup.1 is hydrogen or methyl;
- R.sup.2 is hydrogen, alkyl of 1 to 10 carbons, cycloalkyl of 5 to 10 carbons or aralkyl of 7 to 12 carbons; and
- R.sup.5 is methyl or ethyl.
- 4. The process according to claim 1, where R is hydrogen, alkyl of 1 to 4 carbons, alkenyl of 3 to 5 carbons, benzyl, or 2-cyanoethyl, R.sup.1 is hydrogen or methyl, and R.sup.2 is hydrogen, alkyl of 1 to 4 carbons, or 2,2,6,6-tetramethyl-4-piperidinyl.
CROSS-REFERENCE TO RELATED APPLICATION
This application is a division of copending application Ser. No. 310,408, filed Feb. 13, 1989, now U.S. Pat. No. 4,983,738, which is a continuation-in-part of copending U.S. patent application Ser. No. 84,602, filed Aug. 12, 1987, now abandoned.
US Referenced Citations (11)
Foreign Referenced Citations (6)
Number |
Date |
Country |
226700 |
May 1986 |
CSX |
22997 |
Jan 1981 |
EPX |
0338387 |
Nov 1989 |
EPX |
54-95649 |
Jul 1979 |
JPX |
54-103461 |
Aug 1979 |
JPX |
2197318 |
May 1988 |
GBX |
Non-Patent Literature Citations (2)
Entry |
"Anionic Polymerization to Cationic Polymerization," Encyclopedia of Polymer Science and Engineering, vol. 2, pp. 83, 84 (John Wiley & Sons). |
Wilson B. Lutz et al., "New Derivatives of 2,2,6,6-Tetramethylpiperidine," pp. 1695-1703 (May 1962). |
Divisions (1)
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Number |
Date |
Country |
Parent |
310408 |
Feb 1989 |
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Continuation in Parts (1)
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Number |
Date |
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Parent |
84602 |
Aug 1987 |
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