Claims
- 1. A process for producing a hydroquinone diester derivative which comprisescrystallizing the hydroquinone diester derivative represented by the following formula (1): wherein R1 and R2 are the same or different, each representing an alkyl group, a cycloalkyl group, an aryl group, or a heterocyclic group from a reaction mixture comprising the hydroquinone diester derivative and a catechol diester derivative represented by the following formula (3): wherein R1 and R2 have the same meanings as defined above, and washing the crystallized product, wherein a solvent composed of an organic carboxylic acid and water is used for the crystallization.
- 2. A process according to claim 1, wherein the crystallized product is washed with warm or hot water of a temperature of 40° C. or above.
- 3. A process according to claim 1, wherein the crystallized product is washed with warm or hot water of a temperature of 40 to 100° C.
- 4. A process according to claim 1, wherein the organic carboxylic acid is a C1-10alkyl-carboxylic acid.
- 5. A process according to claim 1, wherein the ratio of the organic carboxylic acid to water contained in the crystallization solvent is 10/90 to 90/10 (weight ratio).
- 6. A process according to claim 1, wherein the crystallized product is separated from the reaction mixture with a solid-liquid separator.
- 7. A process according to claim 1, wherein R1 and R2 in the formula (1) are C1-4 alkyl groups.
- 8. A process according to claim 1, which comprises crystallizing the hydroquinone diester derivative from a reaction mixture which can be obtained by reacting a ketoisophorone derivative represented by the following formula (2): wherein R2 has the same meaning as defined above with an acylating agent in the presence of a catalyst.
- 9. A process according to claim 8, wherein the acylating agent is a carboxylic anhydride and the hydroquinone diester derivative is crystallized with said solvent comprising an organic carboxylic acid corresponding to the carboxylic anhydride and water.
- 10. A process according to claim 1, wherein the crystallized product is washed to give a solid containing the catechol diester of the formula (3) in a proportion of 0 to 2% by weight on a solid matter basis.
- 11. A process according to claim 1, wherein the organic carboxylic acid is acetic acid.
Priority Claims (1)
Number |
Date |
Country |
Kind |
10-372784 |
Dec 1998 |
JP |
|
Parent Case Info
This application is the national phase under 35 U.S.C. §371 of PCT International Application No. PCT/JP99/07246 which has an International filing date of Dec. 24, 1999, which designated the United States of America.
PCT Information
Filing Document |
Filing Date |
Country |
Kind |
PCT/JP99/07246 |
|
WO |
00 |
Publishing Document |
Publishing Date |
Country |
Kind |
WO00/40540 |
7/13/2000 |
WO |
A |
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