Claims
- 1. A process for producing a cyclohexene derivative of the formula: ##STR11## comprising reducing a compound of the formula: ##STR12## by means of a reducing agent which is zinc to form said compound of formula II, said reduction being carried out in a strongly basic homogeneous organic solvent medium at a pH of from 13 to 14.
- 2. A process according to claim 1, wherein the reaction is carried out at pH 14.
- 3. A process according to claim 1, wherein the organic solvent in the water-organic solvent mixture is selected from a group consisting of a lower alcohol containing 1 to 4 carbon atoms, dioxan, tetrahydrofuran, acetone, dimethyl sulfoxide and dimethylformamide.
- 4. A process according to claim 3, wherein the solvent is a lower alcohol containing 1 to 4 carbon atoms.
- 5. A process according to claim 4, wherein the lower alcohol is selected from the group consisting of methanol, ethanol and n-propanol.
- 6. A process according to claim 1 wherein the conversion of the compound of formula I into the compound of formula II is carried out in the presence of a complex former.
- 7. A process according to claim 6, wherein the complex former is selected from the group consisting of an alkali metal cyanide, ethylenediaminetetraacetic acid, ethylenediamine, nitrilotriacetic acid and p-phenanthroline.
- 8. A process according to claim 7, wherein the alkali metal cyanide is sodium cyanide or potassium cyanide.
- 9. A process according to claim 1, wherein the solvent in the aqueous-organic solvent mixture is selected from a group consisting of a lower alcohol containing 1 to 4 carbon atoms, dioxan, tetrahydrofuran, acetone, dimethyl sulfoxide and dimethylformamide.
- 10. A process according to claim 9, wherein the solvent is a lower alcohol containing 1 to 4 carbon atoms.
- 11. A process according to claim 1, wherein the conversion of the compound of formula I into the compound of formula II is carried out in the presence of a complex former.
- 12. A process according to claim 11, wherein the complex former is selected from the group consisting of an alkali metal cyanide, ethylenediaminetetraacetic acid, ethylenediamine, nitrilotriacetic acid and p-phenanthroline.
- 13. A process according to claim 12, wherein the alkali metal cyanide is sodium cyanide or potassium cyanide.
- 14. The process of claim 1 wherein the organic solvent medium contains a mixture of an organic solvent and water.
Priority Claims (1)
Number |
Date |
Country |
Kind |
6626/81 |
Oct 1981 |
CHX |
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Parent Case Info
This is a continuation of application Ser. No. 434,193, filed Oct. 13, 1982, now abandoned.
US Referenced Citations (6)
Foreign Referenced Citations (1)
Number |
Date |
Country |
0077439 |
Apr 1983 |
EPX |
Non-Patent Literature Citations (3)
Entry |
Surmatis et al., J. Org. Chem. 35, 1053 (1970). |
Mayet et al., Helv. Chim. Acta., 50, 1606 (1967). |
Surmatis et al., Helv. Chim. Acta., 53, 974 (1970). |
Continuations (1)
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Number |
Date |
Country |
Parent |
434193 |
Oct 1982 |
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