Claims
- 1. A process for the preparation of 5-(2,4-difluorophenyl) salicylic acid, comprising:
- i) oxidizing 4-(2,4-difluorophenyl)-4'-nitrobenzophenone by Baeyer-Villiger oxidation to 4-(2,4-difluorophenyl)phenyl 4-nitrobenzoate;
- ii) hydrolyzing the obtained 4-(2,4-difluorophenyl)phenyl 4-nitrobenzoate to 4-(2,4-difluorohenyl)phenol; and
- iii) carboxylating the product of step (ii) to 5-(2,4-difluorophenyl) salicylic acid.
- 2. 4-(2,4-difluorophenyl)-4'-nitro-benzophenone.
Priority Claims (1)
Number |
Date |
Country |
Kind |
22441 A/90 |
Dec 1990 |
ITX |
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Parent Case Info
This is a division of application Ser. No. 07/802,398, filed on Dec. 4, 1991 now U.S. Pat. No. 5,142,093.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4225730 |
Jones et al. |
Sep 1980 |
|
4486599 |
Meneghin et al. |
Dec 1984 |
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Divisions (1)
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Number |
Date |
Country |
Parent |
802398 |
Dec 1991 |
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