Claims
- 1. A process for preparing 5,6-dihydroxyindole comprising subjecting a compound of the formula
- wherein R' represents benzyl to a hydrogen transfer operation comprising heating a mixture of said compound of formula II and a hydrogenation catalyst containing 3 to 10 percent palladium or rhodium on charcoal in an alcoholic or aqueous alcoholic medium and in the presence of cyclohexene as a transfer agent.
Parent Case Info
This a continuation of application Ser. No. 07/475,906, filed Feb. 5, 1990, abandoned, which is a continuation of application Ser. No. 07/337,863, filed Apr. 14, 1989, now abandoned, which is a continuation of application Ser. No. 07/172,246, filed Mar. 23, 1988, now abandoned, which is a continuation of application Ser. No. 06/927,723, filed Nov. 7, 1986 abandoned.
US Referenced Citations (4)
Non-Patent Literature Citations (7)
Entry |
Green et al., "Protecting Groups in Organic Chemistry "(1981) p. 90-91. |
McOmie "Protective Groups in Organic Chemistry" (1973) pp. 168-169. |
Walker, J.A.C.S. 77, 3844 (1955). |
Reitz J. Med. Chem. 28, 642-647 (1985). |
Muralidar, Ind. J. Chem. vol. 16B, 1004 (1978). |
Translation of Japan 80/76859 (Fujimoto) (1980). |
Translation of Japan 80/62061 (Ihara) (1980). |
Continuations (4)
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Number |
Date |
Country |
Parent |
475906 |
Feb 1990 |
|
Parent |
337863 |
Apr 1989 |
|
Parent |
172246 |
Mar 1988 |
|
Parent |
927723 |
Nov 1986 |
|