Claims
- 1. A process for preparing a compound of the formula: ##STR55## wherein A is a pyridyl or pyrimidinyl, optionally substituted with not more than three substituents, which comprises reacting a compound of the formula: ##STR56## with a compound of the formula AX, wherein A is as defined above, and X is halogen, in the presence of a base.
- 2. The process according to claim 1, wherein said not more than three substituents are selected from the group consisting of lower alkyl, lower alkanoyl, lower alkyl-substituted silyl, halogen-substituted alkyl, di(lower)alkylamino, phenyl, phenyl(lower)alkyl, phenyl(lower)alkenyl, furyl(lower)alkyl, furyl(lower)alkenyl, halogen, nitro, cyano, --OR.sup.6 (in which R.sup.6 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, lower alkanoyl, phenyl, lower alkoxyphenyl, nitrophenyl, phenyl(lower)alkyl, cyanophenyl(lower)alkyl, benzoyl, tetrahydropyranyl, pyridyl, trifluoromethylpyridyl, pyrimidinyl, benzothiazolyl, quinolyl, benzoyl(lower)alkyl, benzenesulfonyl or lower alkylbenzenesulfonyl) and --CH.sub.2 Z'--R.sup.7 (in which Z' is --O--, --S--, --SO-- or --NR-- (R being hydrogen or lower alkyl) and R.sup.7 is phenyl, halophenyl, lower alkoxyphenyl, pyridyl or pyrimidinyl).
- 3. The process according to claim 1, wherein the pyridyl or pyrimidinyl group is unsubstituted.
- 4. The process according to claim 1, wherein the pyridyl or pyrimidinyl group is substituted with trifluoromethyl.
Priority Claims (2)
Number |
Date |
Country |
Kind |
1-124059 |
May 1989 |
JPX |
|
1-341175 |
Dec 1989 |
JPX |
|
Parent Case Info
This is a divisional application of Ser. No. 08/279,003, filed Jul. 22, 1994, now U.S. Pat. No. 5,406,877, which is a divisional of Ser. No. 07/962,345, filed Oct. 16, 1992; now U.S. Pat. No. 3,371,222 which is a divisional of Ser. No. 07/524,056, filed May 16, 1990, now U.S. Pat. No. 5,185,342.
US Referenced Citations (4)
Number |
Name |
Date |
Kind |
3219694 |
Yates |
Nov 1965 |
|
4829085 |
Wenderoth et al. |
May 1989 |
|
5057146 |
Anthony et al. |
Oct 1991 |
|
5157144 |
Anthony et al. |
Oct 1992 |
|
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Number |
Date |
Country |
0023891 |
Feb 1981 |
EPX |
0253213 |
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EPX |
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Divisions (3)
|
Number |
Date |
Country |
Parent |
279003 |
Jul 1994 |
|
Parent |
962345 |
Oct 1992 |
|
Parent |
524056 |
May 1990 |
|