Claims
- 1. A process for the preparation of .alpha.-tocopherol by a condensation reaction between trimethylhydroquinone represented by the following formula (I): ##STR9## and a phytol derivative represented by the following formula (II): ##STR10## wherein L means a hydroxy group, a halogen atom, an acetoxy, methanesulfonyloxy, ethanesulfonyloxy, benzenesulfonyloxy or toluenesulfonyloxy group, or isophytol represented by the following formula (III): ##STR11## which comprises conducting the condensation reaction in the presence of a carbonate ester as a solvent and Lewis acid excepting for ZnCl.sub.2 as a catalyst.
- 2. The process for the preparation of .alpha.-tocopherol as claimed in claim 1, wherein the Lewis acid is ZnBr.sub.2.
Priority Claims (2)
Number |
Date |
Country |
Kind |
6-175167 |
Jul 1994 |
JPX |
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6-282309 |
Nov 1994 |
JPX |
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Parent Case Info
This is a continuation-in-part of Ser. No. 08/826,504, now U.S. Pat. No. 5,886,197 filed Apr. 3, 1997, which is a divisional of Ser. No. 08/460,667, filed Jun. 2, 1995, now U.S. Pat. No. 5,663,376.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
5663376 |
Hirose et al. |
Sep 1997 |
|
5886197 |
Hirose et al. |
Mar 1999 |
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Divisions (1)
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Number |
Date |
Country |
Parent |
460667 |
Jun 1995 |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
826504 |
Apr 1997 |
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