Claims
- 1. A process for the preparation of a hydroxybenzaldoxime O-ether of the formula ##STR17## in which R.sup.1 represents alkyl with 1 to 10 carbon atoms, wherein a tert.-butoxy-benzaldoxime of the formula ##STR18## is reacted with an alkylating agent of the formula
- R.sup.1 --X
- in which and
- R.sup.1 has the abovementioned meaning
- X represents halogen or OSO.sub.2 OR.sup.1,
- wherein
- R.sup.1 has the abovementioned meaning, in the presence of an alkali metal hydroxide, in the presence of a phase transfer catalyst selected from tetraalkylammonium salts and tetraalkylphosphonium salts, and in the presence of a diluent selected from aromatic hydrocarbons and chlorinated aromatic hydrocarbons, at temperatures between 0.degree. C. and 50.degree. C., and the products are then treated with an anhydrous acid selected from trifluoractive acid, methanesulphonic acid, perfluoroalkanecarboxylic acid and hydrogen halide, at a temperature between 0.degree. C. and 50.degree. C.
- 2. Process according to claim 1, wherein the alkylating agent employed
- R.sup.1 represents alkyl with 1 to 10 carbon atoms and
- X represents chlorine, bromine, iodine or the radical of the formula --OSO.sub.2 OR.sup.1,
- wherein
- R.sup.1 again represents alkyl with 1 to 10 carbon atoms.
- 3. A process according to claim 1, wherein the reaction carried out at temperatures between 10.degree. C. and 30.degree. C.
Priority Claims (1)
Number |
Date |
Country |
Kind |
3620166 |
Jun 1986 |
DEX |
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Parent Case Info
This is a continuation of application Ser. No. 057,879, filed June 2, 1987, and now abandoned.
US Referenced Citations (3)
Foreign Referenced Citations (7)
Number |
Date |
Country |
0023890 |
Feb 1981 |
EPX |
0076370 |
Apr 1983 |
EPX |
0083010 |
Jul 1983 |
EPX |
0121701 |
Oct 1984 |
EPX |
0158159 |
Oct 1985 |
EPX |
0218123 |
Apr 1987 |
EPX |
2927117 |
Jan 1981 |
DEX |
Non-Patent Literature Citations (4)
Entry |
McOmie(I), "Protective Groups in Organic Chemistry", pp. 149, 157 and 159 (1973). |
Palazzo et al., "Chemical Abstracts", vol. 58, p. 4548a (1963). |
Hiraoka, "Studies in Organic Chemistry", 12, pp. 167-168, and 175-176 (1982). |
McOmie, "Protective Groups in Organic Chemistry", 96-97 (1973). |
Continuations (1)
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Number |
Date |
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Parent |
57879 |
Jun 1987 |
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