Claims
- 1. A compound of the formula: ##STR3## wherein R.sup.1 is hydrogen or a hydrogenolytically removable carboxy protecting group.
- 2. A compound as claimed in claim 1 wherein R.sup.1 is a hydrogenolytically removable ester group residue.
- 3. A compound as claimed in claim 2, wherein said ester group residue is alkyl of 1 to 12 carbon atoms, alkylthio of 1 to 12 carbon atoms, halogeno or aroyl.
- 4. A compound as claimed in claim 3, wherein said ester group residue is ethyl or methyl.
- 5. The compound of the formula: ##STR4##
CROSS REFERENCE TO RELATED APPLICATION
This is a continuation-in-part of Ser. No. 08/063,434 filed May 18, 1993, now U.S. Pat. No. 5,319,098, the disclosure of which is incorporated herein by reference.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
5319098 |
Burbaum et al. |
Jun 1994 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
0523449A2 |
Jan 1993 |
EPX |
Non-Patent Literature Citations (4)
Entry |
Blacklock et al., "Synthesis of Semisynthetic Dipeptides Using N-Carboxyanhydrides and Chiral Induction on Raney Nickel. A Method Practical for Large Scale", J. Organic Chem., 53, pp. 836-844 (1988). |
"Imidapril Hydrochloride", Drugs of the Future, Prous Science, 17(7), pp. 551-558 (1992). |
Kleeman et al., Pharmazeutische Wirkstoffe, pp. 1154-1155 (1987). |
Mukaiyama et al., "A Novel Method for the Preparation of Optically Active Dipeptide. Chemo-and Stereoselective Reduction of 2-Hydroxyimino Amides with Samarium Diiodide", Chemistry Letters, pp. 181-184 (1992). |
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
63434 |
May 1993 |
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