Claims
- 1. In a process for controlling the timed release of active material from a retarded active material composition containing polysoluble adjuvant materials which is melt granulated, pressed and tableted, wherein the improvement comprises increasing the rate of release of active material by homogeneously admixing therewith prior to melt-granulating methylcellulose or carboxymethylcellulose at an increasing viscosity of from 0.02 to 40 pa.s.
- 2. In a process for controlling the timed release of active material from a retarded active material composition containing castor oil, stearic acid and lactose which is melt granulated, pressed and tableted, wherein the improvement comprises adjusting the rate of release of active material by homogeneously admixing therewith prior to melt granulating carboxy methylcellulose at viscosity stages of 0.05, 0.3, 0.6, 3, 6, 20 or 40 Pa.s.
CROSS REFERENCE TO RELATED APPLICATIONS
This is a continuation of U.S. Ser. No. 795,756 of Nov. 8, 1985, which, in turn is a continuation of U.S. Ser. No. 391,020 filed June 22, 1982, and both now abandoned.
US Referenced Citations (12)
Foreign Referenced Citations (1)
Number |
Date |
Country |
0068446 |
Dec 1985 |
EPX |
Non-Patent Literature Citations (1)
Entry |
Chemical Abstracts, Pharmacodynamics, vol. 79, 1973, p. 25, Abstract 61534E. |
Continuations (2)
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Number |
Date |
Country |
Parent |
795756 |
Nov 1985 |
|
Parent |
391020 |
Jun 1982 |
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