Claims
- 1. (Amended) A method of making a complex for delivery to a cell, comprising: covalently forming a polymer, from monomers, in the presence of a polyion, the polymer is formed outside of any cell, resulting in a polymer-polyion complex for delivery to a cell, wherein the polyion is not removed from the complex prior to administration.
- 2. The method of claim 1 wherein the polyion is a polyanion.
- 3. The method of claim 2 wherein a complex is formed comprising the polyanion and an amphipathic compound.
- 4. The method of claim 2 wherein a complex is formed comprising the polyion and a cationic compound.
- 5. The method of claim 9 wherein the cationic compound is selected from the group consisting of histone, polylysine and protamine.
- 6. A monomer for forming a polymer having the general structure comprising:
- 7. A monomer for forming a polymer having the general structure comprising:
- 8. A monomer for forming a polymer having the general structure comprising:
- 9. A polymer containing a repeating unit comprising:
- 10. A nucleic acid binding polymer comprising:
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001]1(Provisional Application Serial No.)(Filing Date)60/009,5931/4/96(Divisional Application Serial No.)(Filing Date)08/778,6571/3/97
Provisional Applications (1)
|
Number |
Date |
Country |
|
60009593 |
Jan 1996 |
US |
Divisions (2)
|
Number |
Date |
Country |
Parent |
09464871 |
Dec 1999 |
US |
Child |
10005294 |
Dec 2001 |
US |
Parent |
08778657 |
Jan 1997 |
US |
Child |
10005294 |
Dec 2001 |
US |