PROCESSES FOR DETECTING TOXIC SUBSTANCES

FILED OF THE INVENTION

This invention relates to biology-based processes for detecting toxic substances, and specifically to processes for detecting toxic substances which comprises detecting mRNA that is transcribed in the presence of test materials by a particular gene from yeast.

BACKGROUND ART

Environmental chemical fate search has been conducted every year for 24 years from 1974 through 1998 by Environment Agency, and revealed that about 40% of 775 chemical substances that have been searched so far are emitted into the environment. Chemical substances that are industrially produced at the present in Japan are estimated about 50,000, and the production scale and the kinds of chemical substances are increasing year by year. It is known that chemical substances that are accidentally produced by water treatment with chlorine and incineration pollute the environment. Although such facts allow us to predict that there are a large number of chemical substances that have been accumulated in the environment, it is extremely difficult to search and examine individually the all chemical substances.

Conventional bioassays (approaches to evaluate the harmful effects on biological materials on the basis of their responses) wherein inhibited growth and particular biological responses in individuals and cells of fishes, daphnia and shellfish are used as indicators make it possible to determine the presence or absence of the toxicity of chemical substances in the environment, but neither possible to evaluate the characters nor origins of the toxicity. The evaluation methods based on the activity of nitrite-forming bacteria or nitrate-forming bacteria (Japanese Patent Publication (kokai) No. 123705/1994, Japanese Patent Publication (kokai) No. 2000-206087) and the activity of iron bacteria have been proposed, and devices such as Acute toxiciants monitor (Fuji Electric Corporate Research and Development, Ltd. Japan) are marketed in Japan. In foreign countries, the devices for evaluation based on emission intensity of luminous bacteria are commercially available (MICROTOX, azur, Co., USA; LUMIS, drlange, Co. Germany). However, those devices still involve conventional bioassays, and never provide any detailed information of toxic chemical substances.

In Japan, the risk control of chemical substances is reconsidered every time a chemical substance pollution is newly found, and official regulations and self-imposed regulations are combined to organize the system for risk control. However, any system has not been yet organized that could quickly respond to the present complicated and diversified conditions including accidental productions and environmental emission of toxic chemical substance as typified by trihalomethane and dioxin. Animal experiments as used in the method for evaluation of toxic substance of “Law Concerning Examination and Manufacture, etc. of Chemical Substances” are expensive and time-consuming, and are not accepted across the world. Although, as such, the control system has been continuously discussed, it has not been successfully accomplished because there is no way to dissolve the problem. Thus, a method for detect readily chemical substances occurring in the environment is desired.

DISCLOSURE OF THE INVENTION

The inventors of the present application found that a toxic substance induces the expression of mRNA from particular yeast genes, and accomplished the present invention.

Specifically, the invention of the present application relates a process for detecting a toxic substance, which comprises detecting mRNA that is expressed in the presence of a test material by a cell comprising a yeast gene that is selected from a group consisting of the following, or a gene that is homologous to the yeast genes and is derived from other species, wherein the mRNA corresponds to said yeast gene or said homologous gene thereof:

YBR072W, YCR102C, YCR107W, YDL218W, YDL243C, YDR453C, YDR533C, YFL014W, YFL056C, YFL057C, YGR110W, YJR155W, YKL071W, YKR076W, YLL060C, YLR460C, YMR090W, YNL331C, YNL332W, YNL335W, YOL150C, YOL165C, YPL171C, YPR167C, YBL048W, YBL064C, YBL107C, YBR008C, YBR173C, YBR256C, YBR296C, YDL021W, YFL022C, YFL024C, YFL061W, YGL121C, YGL158W, YGR043C, YHR029C, YHR112C, YHR139C, YHR179W, YHR209W, YIR030C, YJR010W, YJR048W, YKL001C, YKL107W, YKR075C, YKR097W, YLL056C, YLR297W, YLR303W, YML087C, YMR096W, YNL274C, YOL151W, YOR226C, YOR338W, YOR391C, YPL280W, YDR406W, YJL153C, YLR346C, YOR049C, YOR153W, YPL088W, YAL034C, YDL124W, YDL174C, YDR476C, YGL156W, YGR035C, YGR157W, YGR213C, YGR281W, YGR284C, YHL047C, YHR043C, YHR044C, YHR054C, YJR073C, YKL165C, YLR008C, YMR315W, YNL211C, YOL031C, YOL101C, YOR303W, YAL005C, YAR031W, YBL005W-A, YBL022C, YBL041W, YBL049W, YBL075C, YBL078C, YBR062C, YBR169C, YBR294W, YCL020W, YCL035C, YCL043C, YCL050C, YCL057W, YCR012W, YCR013C, YCR060W, YDL007W, YDL027C, YDL097C, YDL110C, YDL126C, YDL169C, YDR070C, YDR155C, YDR158W, YDR204W, YDR210W, YDR214W, YDR258C, YDR313C, YDR368W, YDR435C, YER012W, YER037W, YER091C, YER103W, YFL044C, YFR003C, YFR010W, YFR020W, YFR024C, YFR044C, YFR053C, YGL006W, YGL048C, YGL062W, YGL141W, YGL157W, YGL163C, YGL180W, YGL184C, YGR010W, YGR028W, YGR032W, YGR048W, YGR124W, YGR135W, YGR142W, YGR161C, YGR192C, YGR197C, YGR201C, YGR212W, YGR231C, YGR244C, YGR254W, YGR268C, YHL030W, YHR016C, YHR018C, YHR055C, YHR087W, YHR166C, YIL160C, YIR017C, YJL034W, YJL048C, YJL052W, YJL144W, YJL163C, YJR009C, YJR069C, YJR074W, YJR130C, YJR149W, YKL065C, YKL073W, YKL103C, YKL142W, YKL210W, YKL218C, YKR011C, YKR018C, YKR046C, YKR049C, YLL024C, YLL026W, YLR027C, YLR080W, YLR107W, YLR121C, YLR132C, YLR133W, YLR155C, YLR158C, YLR161W, YLR195C, YLR217W, YLR328W, YLR336C, YLR345W, YLR370C, YLR423C, YML004C, YML092C, YML128C, YML130C, YML131W, YMR040W, YMR118C, YMR214W, YMR251W, YMR297W, YMR322C, YNL036W, YNL055C, YNL071W, YNL094W, YNL134C, YNL155W, YNL160W, YNL239W, YNL241C, YOL005C, YOR020C, YOR027W, YOR037W, YOR059C, YOR120W, YOR134W, YOR152C, YOR173W, YOR289W, YOR362C, YPL240C, YPR030W, YAL008W, YAL023C, YAL060W, YAL062W, YAR009C, YBL101C, YBR006W, YBR046C, YBR052C, YBR053C, YBR056W, YBR099C, YBR137W, YBR139W, YBR149W, YBR170C, YBR177C, YBR203W, YBR207W, YBR212W, YBR239C, YBR284W, YBR293W, YCL018W, YCL033C, YCL040W, YCL049C, YCR062W, YCR067C, YCR082W, YDL010W, YDL020C, YDL024C, YDL054C, YDL095W, YDL100C, YDL115C, YDL144C, YDL198C, YDL223C, YDL245C, YDL246C, YDR001C, YDR032C, YDR058C, YDR072C, YDR127W, YDR168W, YDR169C, YDR188W, YDR231C, YDR261C, YDR264C, YDR272W, YDR293C, YDR304C, YDR330W, YDR403W, YDR411C, YDR427W, YDR436W, YDR497C, YDR511W, YDR516C, YDR519W, YDR545W, YEL012W, YEL030W, YER004W, YER009W, YER021W, YER035W, YER053C, YER079W, YER094C, YER096W, YER125W, YER158C, YER163C, YER175C, YER177W, YER178W, YER185W, YFL006W, YFL010C, YFL016C, YFL029C, YFL030W, YFL031W, YFL032W, YFL038C, YFL041W, YFR004W, YFR047C, YFR050C, YFR052W, YGL011C, YGL013C, YGL037C, YGL047W, YGL053W, YGL091C, YGL094C, YGL127C, YGL150C, YGL199C, YGL207W, YGL248W, YGR008C, YGR037C, YGR055W, YGR101W, YGR130C, YGR154C, YGR194C, YGR221C, YGR232W, YGR248W, YGR253C, YGR256W, YHL008C, YHR027C, YHR053C, YHR057C, YHR111W, YHR138C, YHR161C, YHR164C, YHR169W, YHR174W, YHR176W, YHR199C, YIL010W, YIL034C, YIL041W, YIL045W, YIL087C, YIL107C, YIL142W, YIL155C, YIR034C, YIR036C, YIR037W, YIR038C, YIR039C, YJL001W, YJL031C, YJL035C, YJL053W, YJL057C, YJL066C, YJL068C, YJL082W, YJL099W, YJL102W, YJL151C, YJL152W, YJL161W, YJL164C, YJL171C, YJL172W, YJL210W, YJL219W, YJR008W, YJR045C, YJR046W, YJR106W, YJR117W, YJR137C, YKL007W, YKL026C, YKL035W, YKL091C, YKL104C, YKL117W, YKL145W, YKL146W, YKL151C, YKL152C, YKL153W, YKL193C, YKL195W, YKL213C, YKL215C, YLL028W, YLL039C, YLL058W, YLR054C, YLR103C, YLR120C, YLR136C, YLR149C, YLR152C, YLR178C, YLR259C, YLR299W, YLR324W, YLR327C, YLR348C, YLR350W, YLR356W, YLR362W, YLR387C, YLR429W, YML054C, YML070W, YML100W, YML117W, YML125C, YMR004W, YMR008C, YMR009W, YMR020W, YMR067C, YMR089C, YMR097C, YMR102C, YMR105C, YMR107W, YMR152W, YMR180C, YMR184W, YMR191W, YMR219W, YMR271C, YMR275C, YMR295C, YMR314W, YMR316W, YNL006W, YNL007C, YNL012W, YNL044W, YNL045W, YNL074C, YNL092W, YNL093W, YNL104C, YNL115C, YNL156C, YNL231C, YNL234W, YNL237W, YNL281W, YNL305C, YNL333W, YNR010W, YNR019W, YNR033W, YNR059W, YNR068C, YNR069C, YOL032W, YOL036W, YOL047C, YOL071W, YOL082W, YOL083W, YOL117W, YOL119C, YOL126C, YOL131W, YOL153C, YOL162W, YOL163W, YOL164W, YOR019W, YOR035C, YOR036W, YOR099W, YOR117W, YOR124C, YOR130C, YOR132W, YOR157C, YOR185C, YOR197W, YOR259C, YOR261C, YOR273C, YOR288C, YOR332W, YOR336W, YOR347C, YPL017C, YPL087W, YPL106C, YPL109C, YPL149W, YPL154C, YPL196W, YPL206C, YPL222W, YPR023C, YPR024W, YPR026W, YPR067W, YPR103W, YPR108W, YPR151C, YAL012W, YBR029C, YBR222C, YCL009C, YCL027W, YCL064C, YCR098C, YDL222C, YDR055W, YDR077W, YDR502C, YEL001C, YEL042W, YER026C, YER106W, YGR136W, YGR138C, YHR137W, YHR142W, YIL023C, YIL153W, YJL073W, YJR004C, YJR054W, YKL039W, YKL086W, YKL163W, YKR091W, YLR109W, YLR194C, YLR250W, YMR095C, YMR189W, YNL106C, YNL169C, YNL322C, YOR181W, YOR198C, YOR208W, YOR247W, YPL089C, YAL038W, YAL053W, YBR023C, YBR214W, YBR295W, YCR048W, YDL072C, YDL204W, YDR085C, YDR098C, YDR259C, YDR380W, YDR388W, YDR391C, YDR432W, YDR481C, YDR510W, YER069W, YGL022W, YGL126W, YGL209W, YGL255W, YGR189C, YGR282C, YHL035C, YHR030C, YIL022W, YIL024C, YIL117C, YIL123W, YIL140W, YIL154C, YJL088W, YJL108C, YJL149W, YJL159W, YJL186W, YJR148W, YKL096W, YLR180W, YLR273C, YLR300W, YLR307W, YLR378C, YLR391W, YMR094W, YMR104C, YMR276W, YMR296C, YNL190W, YNL208W, YNL300W, YNR064C, YOL013C, YOL058W, YOR248W, YOR355W, YPL052W, YPL163C, YPR079W, YAR028W, YBR146W, YBR183W, YCL038C, YCR071C, YDL008W, YDR019C, YDR031W, YDR115W, YDR486C, YER038C, YER130C, YFL054C, YGL136C, YGR146C, YGR207C, YHL040C, YIL167W, YJL020C, YKR039W, YLR031W, YLR205C, YMR072W, YMR140W, YMR173W, YMR195W, YMR226C, YNL037C, YNR002C, YOL143C, YOR136W, YOR215C, YOR382W, YOR383C, YPL054W, YPL271W, YPR127W, YAL044C, YAL054C, YAR010C, YAR027W, YAR071W, YBL001C, YBL043W, YBL057C, YBR014C, YBR024W, YBR035C, YBR068C, YBR111C, YBR116C, YBR147W, YBR168W, YBR246W, YBR273C, YCR004C, YCR021C, YCR037C, YCR088W, YDL022W, YDL128W, YDL238C, YDR003W, YDR009W, YDR033W, YDR084C, YDR104C, YDR270W, YDR315C, YDR340W, YDR357C, YDR358W, YDR396W, YDR405W, YDR410C, YDR434W, YDR482C, YDR487C, YDR520C, YDR534C, YDR539W, YEL011W, YEL065W, YEL066W, YER039C, YER044C, YER067W, YER080W, YER107C, YFL020C, YFL028C, YFL043C, YFR015C, YGL001C, YGL008C, YGL068W, YGL073W, YGL104C, YGL113W, YGL154C, YGL167C, YGL229C, YGL242C, YGL249W, YGL253W, YGR052W, YGR060W, YGR065C, YGR106C, YGR111W, YGR220C, YGR257C, YHL023C, YHL048W, YHR004C, YHR037W, YHR071W, YHR092C, YHR190W, YIL007C, YIL033C, YIL070C, YIL088C, YIL111W, YIR002C, YIR016W, YIR035C, YIR043C, YJL012C, YJL083W, YJL089W, YJL116C, YJL131C, YJL132W, YJL196C, YJR061W, YJR086W, YJR142W, YJR161C, YKL008C, YKL013C, YKL041W, YKL067W, YKL138C, YKL139W, YKL150W, YKL175W, YKR006C, YKR014C, YKR070W, YLL023C, YLR023C, YLR093C, YLR118C, YLR142W, YLR225C, YLR241W, YLR251W, YLR252W, YLR270W, YML030W, YML110C, YMR021C, YMR027W, YMR148W, YMR181C, YMR262W, YMR272C, YMR298W, YNL011C, YNL130C, YNL214W, YNL259C, YOL129W, YOR042W, YOR052C, YOR137C, YOR149C, YOR165W, YOR270C, YOR285W, YOR367W, YPL018W, YPL156C, YPL186C, YPL203W, YPL216W, YPL255W, YPR006C, YPR073C, YPR098C, YBR050C, YBR145W, YBR299W, YDR518W, YEL020C, YFL062W, YGL039W, YGL134W, YJL217W, YJR159W, YLR126C, YNL249C, YNL284C, YNL336W, YOL157C, YOR344C, YOR381W, YPL265W, YPR124W, YBR074W, YBR109C, YBR126C, YBR201W, YCR005C, YDL248W, YDR041W, YDR105C, YDR268W, YDR452W, YEL075C, YER046W, YER050C, YER136W, YER159C, YGL250W, YGR019W, YGR042W, YGR053C, YGR066C, YGR247W, YGR255C, YGR295C, YHL044W, YHR145C, YIL058W, YIL065C, YIL083C, YIL098C, YIL172C, YJL030W, YJL185C, YJL213W, YJR029W, YJR099W, YJR122W, YJR125C, YKL190W, YKR020W, YLL025W, YLL051C, YLR043C, YLR090W, YLR100W, YLR108C, YLR290C, YML068W, YMR051C, YMR139W, YMR178W, YMR193W, YNL015W, YNL079C, YNL122C, YNL223W, YNL285W, YNL293W, YNR007C, YNR035C, YNR061C, YOL016C, YOL104C, YOR220W, YOR221C, YOR374W, YPL123C, YPR077C, YPR107C, YPR147C, YBR093C, YBR196C, YEL041W, YEL047C, YER023W, YER119C, YFL055W, YGR209C, YIL124W, YKL187C, YLL055W, YMR318C, YOL152W, YAL007C, YBR067C, YBR115C, YBR285W, YBR292C, YDL043C, YDL123W, YDL131W, YDL168W, YDL212W, YDR056C, YDR132C, YDR154C, YDR183W, YDR216W, YDR253C, YDR295C, YDR494W, YDR513W, YEL072W, YER045C, YER061C, YER181C, YFL052W, YFL058W, YFR030W, YGL089C, YGL096W, YGL114W, YGL193C, YGL202W, YGL204C, YGL259W, YGR006W, YGR070W, YGR088W, YHL034C, YHL036W, YHR048W, YHR104W, YHR163W, YIL060W, YIL136W, YIR024C, YJL036W, YJL045W, YJL060W, YJL101C, YJL155C, YJR085C, YJR109C, YJR156C, YKL070W, YKL161C, YKL221W, YKR071C, YLL009C, YLL050C, YLR092W, YLR145W, YLR156W, YLR163C, YLR220W, YLR280C, YLR311C, YLR390W, YML116W, YMR034C, YMR038C, YMR081C, YMR250W, YNL240C, YNL260C, YNL277W, YNR074C, YOL044W, YOL084W, YOL147C, YOL159C, YOR184W, YOR228C, YOR255W, YPL223C, YPR160W, YDL182W, YBR047W, YBR054W, YBR291C, YDR069C, YER124C, YER131W, YGR044C, YIL094C, YKR007W, YMR240C, YNR050C, YOR007C, YAL015C, YBL065W, YBR105C, YBR182C, YBR186W, YBR244W, YBR272C, YCL069W, YDL025C, YDL059C, YDL085W, YDL113C, YDL244W, YDR018C, YDR054C, YDR202C, YDR223W, YDR350C, YDR353W, YDR374C, YDR512C, YEL052W, YEL070W, YER098W, YFR017C, YGL046W, YGL067W, YGL098W, YGL117W, YGL146C, YGL240W, YGR011W, YGR067C, YGR133W, YGR153W, YGR223C, YHR116W, YHR124W, YIL097W, YIL168W, YJL103C, YJL221C, YJR036C, YJR095W, YKL085W, YKL133C, YKL162C, YKL188C, YKL217W, YKR061W, YKR105C, YLL062C, YLR174W, YLR216C, YLR247C, YLR260W, YLR267W, YLR389C, YML007W, YMR041C, YMR177W, YMR253C, YNL009W, YNL117W, YNL128W, YNL183C, YNR073C, YOL133W, YOL158C, YOR133W, YOR225W, YOR227W, YPL161C, YPL166W, YPL202C, YPL224C, YPR015C, YPR086W, YPR201W, YAL061W, YAL067C, YAR007C, YBL033C, YBL056W, YBL086C, YBR026C, YBR073W, YBR101C, YBR117C, YBR123C, YBR213W, YBR269C, YBR280C, YCR036W, YDL132W, YDL149W, YDL200C, YDL234C, YDL242W, YDR099W, YDR177W, YDR256C, YDR392W, YDR394W, YDR531W, YEL071W, YER014W, YER042W, YER090W, YER184C, YFL059W, YFR042W, YFR046C, YFR049W, YGL026C, YGL058W, YGL185C, YGL227W, YGL252C, YGL254W, YGR089W, YGR112W, YGR134W, YGR276C, YHL019C, YHR012W, YHR017W, YHR028C, YHR106W, YHR109W, YHR156C, YIL036W, YIL046W, YIL143C, YIL152W, YIL159W, YIL164C, YJL071W, YJL094C, YJL154C, YJR056C, YJR072C, YJR110W, YJR139C, YKL025C, YKL034W, YKL064W, YKL171W, YKL196C, YKR012C, YKR068C, YKR069W, YLL001W, YLL057C, YLL061W, YLR064W, YLR070C, YLR099C, YLR144C, YLR157C, YLR160C, YLR164W, YLR364W, YLR421C, YML032C, YML042W, YML112W, YML118W, YMR114C, YMR115W, YMR258C, YNL181W, YNL191W, YNL212W, YNL213C, YNL250W, YNL265C, YNL312W, YNR032W, YOL038W, YOL049W, YOL064C, YOR088W, YOR155C, YOR257W, YOR265W, YOR377W, YOR386W, YPL031C, YPL113C, YPL124W, YPL151C, YPL249C, YPL260W, YPL274W, YPR048W, YPR061C, YPR093C, YPR125W, YPR158W, YPR168W, YPR169W, YPR174C, YPR180W, YPR193C, YPR200C, YAL014C, YAL017W, YAL049C, YBL019W, YBL058W, YBR001C, YBR013C, YBR018C, YBR037C, YBR045C, YBR051W, YBR063C, YBR128C, YBR129C, YBR204C, YBR241C, YBR255W, YBR281C, YCL044C, YCL055W, YCR014C, YCR019W, YCR024C, YCR105W, YDL065C, YDL089W, YDL143W, YDL173W, YDL193W, YDL197C, YDL206W, YDL230W, YDL233W, YDR040C, YDR071C, YDR078C, YDR109C, YDR140W, YDR194C, YDR212W, YDR221W, YDR257C, YDR271C, YDR287W, YDR294C, YDR316W, YDR329C, YDR338C, YDR369C, YDR421W, YDR425W, YDR485C, YDR488C, YDR504C, YDR505C, YDR506C, YDR515W, YEL005C, YEL037C, YEL044W, YER017C, YER048C, YER052C, YER078C, YER089C, YER092W, YER100W, YER162C, YER182W, YFL021W, YFL042C, YFR045W, YFR051C, YFR056C, YGL040C, YGL041C, YGL045W, YGL057C, YGL093W, YGL105W, YGL125W, YGL166W, YGL181W, YGL183C, YGL215W, YGL216W, YGL221C, YGL223C, YGR007W, YGR029W, YGR155W, YGR156W, YGR186W, YGR198W, YGR210C, YGR211W, YGR237C, YGR250C, YGR258C, YGR266W, YGR270W, YGR274C, YGR277C, YHL021C, YHL037C, YHL038C, YHR082C, YHR083W, YHR134W, YHR160C, YHR171W, YHR180W, YHR205W, YIL062C, YIL072W, YIL075C, YIL099W, YIL108W, YIL165C, YIL170W, YIR009W, YIR018W, YIR031C, YIR032C, YJL032W, YJL049W, YJL128C, YJL165C, YJR044C, YJR052W, YJR090C, YJR091C, YJR103W, YJR104C, YJR153W, YKL059C, YKL079W, YKL090W, YKL094W, YKL192C, YKL209C, YKR052C, YKR102W, YKR106W, YLL054C, YLR025W, YLR097C, YLR200W, YLR226W, YLR248W, YLR266C, YLR392C, YLR427W, YML013W, YML029W, YML041C, YML051W, YML078W, YML079W, YML088W, YML099C, YMR056C, YMR068W, YMR091C, YMR110C, YMR160W, YMR186W, YMR255W, YNL005C, YNL026W, YNL039W, YNL063W, YNL064C, YNL077W, YNL083W, YNL147W, YNL176C, YNL194C, YNL253W, YNL257C, YNL261W, YNL264C, YNL276C, YNR006W, YNR034W, YNR047W, YNR051C, YNR071C, YOL065C, YOL067C, YOR005C, YOR008C, YOR022C, YOR023C, YOR058C, YOR069W, YOR087W, YOR138C, YOR229W, YOR256C, YOR267C, YPL005W, YPL020C, YPL022W, YPL105C, YPL147W, YPL150W, YPL152W, YPL164C, YPL168W, YPL180W, YPL188W, YPL194W, YPR025C, YPR047W, YPR049C, YPR066W, YPR081C, YPR134W, YPR140W, YPR148C, YPR155C, YPR172W, YPR185W, YAL018C, YAR064W, YBR012C, YBR076W, YBR287W, YDR043C, YDR250C, YDR373W, YFR014C, YGL191W, YGR180C, YHR136C, YJL026W, YJL037W, YLR038C, YNL058C, YOR031W, YGR087C, YIL166C, YHR008C, YIL129C, YGL256W, YJR030C, YMR077C, YBR264C, YPL177C, YKR040C, YGL056C, YDR128W, YGR139W, YBL101W-A, YOR253W, YOL026C, YDR278C, YHR095W, YCL042W, YNL200C, YPL221W, YLR415C, YMR058W, YPR037C, YER072W, YML028W, YOR325W, YAL039C, YMR112C, YJR107W, YGL088W, YJR058C, YNL142W, YDR090C, YMR071C, YBL093C, YGR293C, YML055W, YDL017W, YDL210W, YGL055W, YCL025C, YDR080W, YDL181W, YNR030W, YJL017W, YIL127C, YDR281C, YDR366C, YFR026C, YJL212C, YPL215W, YEL019C, YBR132C, YHL018W, YNL196C, YPL038W, YAR047C, YPL262W, YHL006C, YPL225W, YBR124W, YOR148C, YKR053C, YBL044W, YER029C, YLR360W, YCL056C, YCR007C, YGR239C, YNL256W, YPR146C, YLR377C, YKL097C, YBR066C, YLR338W, YDL229W, YBR253W, YJR027W, YKL198C, YBL030C, YBR031W, YBR118W, YBR162C, YBR221C, YCR024C-A, YCR106W, YDL046W, YDR012W, YDR133C, YDR134C, YDR276C, YDR342C, YDR343C, YEL027W, YEL034W, YGR038W, YGR243W, YGR279C, YHR094C, YHR105W, YHR175W, YHR181W, YIL056W, YIL162W, YJL059W, YJL097W, YJL158C, YJR105W, YKL051W, YKL056C, YKL097W-A, YKL100C, YKL141W, YKR066C, YLR134W, YLR258W, YLR339C, YML058W, YMR083W, YMR203W, YNL209W, YNL307C, YOL030W, YOR178C, YPL028W, YPR028W, YPR113W, YPR149W, YPR150W, YPR183W, YAL016W, YBL099W, YBL100C, YBR011C, YBR096W, YBR100W, YBR127C, YBR283C, YBR286W, YCL008C, YCL058C, YCR030C, YCR034W, YCR069W, YDL015C, YDL023C, YDL061C, YDL086W, YDR038C, YDR039C, YDR050C, YDR151C, YDR178W, YDR233C, YDR284C, YDR298C, YDR345C, YDR359C, YDR382W, YDR385W, YDR400W, YDR407C, YDR538W, YEL024W, YEL033W, YEL063C, YER057C, YER081W, YER120W, YFL011W, YGL012W, YGL206C, YGR022C, YGR026W, YGR082W, YGR107W, YGR172C, YGR191W, YGR204W, YGR260W, YHL005C, YHL046C, YHR025W, YHR026W, YHR123W, YHR126C, YHR143W, YIL011W, YIL015W, YIL018W, YIL157C, YIR041W, YJL016W, YJL121C, YJL133W, YJL138C, YJL191W, YJR018W, YJR047C, YJR077C, YJR119C, YJR121W, YJR123W, YJR143C, YJR145C, YKL060C, YKL147C, YKL148C, YKL157W, YKL164C, YKL169C, YKR033C, YLL041C, YLL064C, YLR041W, YLR044C, YLR056W, YLR058C, YLR081W, YLR089C, YLR110C, YLR177W, YLR264W, YLR284C, YLR304C, YLR340W, YLR354C, YLR372W, YLR388W, YML022W, YMR007W, YMR011W, YMR015C, YMR092C, YMR101C, YMR156C, YMR205C, YMR215W, YMR261C, YMR323W, YNL069C, YNL135C, YNL195C, YNR076W, YOL039W, YOL073C, YOL086C, YOL120C, YOL156W, YOL161C, YOR002W, YOR009W, YOR010C, YOR085W, YOR108W, YOR128C, YOR129C, YOR142W, YOR161C, YOR176W, YOR230W, YOR298W, YPL004C, YPL036W, YPL048W, YPL057C, YPL059W, YPL061W, YPL135W, YPL179W, YPL218W, YPL220W, YPL246C, YPL272C, YPR063C, YPR080W, YPR181C, YBR290W, YCR010C, YCR091W, YDL107W, YDL129W, YDR066C, YDR529C, YFL026W, YGL018C, YGL059W, YNL144C, YOR003W, YAL037W, YAR023C, YBR003W, YBR020W, YBR044C, YBR091C, YBR185C, YBR282W, YCR015C, YCR038C, YCR043C, YDL119C, YDL146W, YDL220C, YDR057W, YDR123C, YDR125C, YDR222W, YDR225W, YDR277C, YDR286C, YDR347W, YDR408C, YDR438W, YDR479C, YDR483W, YEL039C, YEL057C, YEL073C, YER066W, YER076C, YER084W, YER121W, YER189W, YFL017C, YFL046W, YFR006W, YFR008W, YGL115W, YGL208W, YGL214W, YGL218W, YGR021W, YGR023W, YGR024C, YGR064W, YGR076C, YGR096W, YGR108W, YGR174C, YGR182C, YGR236C, YGR288W, YHL042W, YHR195W, YHR210C, YIL006W, YIL012W, YIL028W, YIL050W, YIL057C, YIL089W, YIL102C, YIL113W, YIL122W, YJL100W, YJL169W, YJL199C, YJR039W, YJR050W, YJR101W, YKL003C, YKL016C, YKL061W, YKL093W, YKL121W, YKL160W, YKL170W, YKL194C, YKR034W, YKR067W, YLR006C, YLR016C, YLR030W, YLR036C, YLR112W, YLR125W, YLR128W, YLR204W, YLR211C, YLR233C, YLR257W, YLR288C, YLR326W, YLR334C, YLR395C, YLR408C, YLR414C, YLR444C, YML050W, YML107C, YML120C, YMR031C, YMR053C, YMR073C, YMR162C, YMR204C, YMR206W, YMR284W, YNL010W, YNL025C, YNL127W, YNL139C, YNL217W, YOL116W, YOL118C, YOR053W, YOR100C, YOR103C, YOR122C, YOR150W, YOR187W, YOR251C, YOR312C, YOR327C, YOR348C, YOR352W, YOR388C, YOR394W, YPL001W, YPL033C, YPL066W, YPL148C, YPL230W, YPL275W, YPL276W, YPR005C, YPR014C, YPR192W, YPR194C, YBR005W, YER025W, YFL027C, YGL080W, YGL205W, YHL028W, YHR185C, YIL076W, YJL166W, YLR046C, YMR035W, YMR238W, YMR252C, YNL192W, YNL202W, YOL108C, YOR385W, YPR165W, YAR033W, YBL038W, YBR009C, YBR010W, YBR151W, YCL067C, YCR096C, YDL137W, YDL192W, YDR073W, YDR086C, YDR224C, YDR377W, YDR378C, YER015W, YGL187C, YHR162W, YJL167W, YJL216C, YKR009C, YLR165C, YMR197C, YNL157W, YOL002C, YOL109W, YOR180C, YPL010W, YPL233W, YBR036C, YDR297W, YGR149W, YGR224W, YNL043C, YPL067C, YPL170W, YCR046C, YDR387C, YFL050C, YGL051W, YHR132C, YIL112W, YJL141C, YKR098C, YLR052W, YLR206W, YML129C, YNL203C, YNR014W, YOL043C, YOL096C, YPR184W, YAL028W, YAL055W, YAR062W, YBL095W, YBL102W, YBR122C, YBR157C, YBR161W, YBR251W, YBR298C, YCR039C, YCR083W, YDL018C, YDL067C, YDL078C, YDL091C, YDL215C, YDL216C, YDR022C, YDR067C, YDR079W, YDR181C, YDR186C, YDR196C, YDR262W, YDR306C, YDR319C, YER188W, YGL004C, YGL035C, YGR036C, YGR062C, YGR120C, YGR131W, YGR141W, YGR167W, YGR287C, YHL024W, YHR080C, YHR097C, YIL077C, YJL046W, YJL070C, YJL096W, YJL113W, YJL146W, YJL180C, YJR019C, YJR049C, YKR058W, YLL005C, YLR078C, YLR151C, YLR271W, YLR295C, YLR351C, YLR375W, YMR023C, YMR025W, YMR135C, YMR210W, YMR267W, YMR278W, YMR293C, YNL073W, YNR037C, YNR040W, YNR072W, YOR028C, YOR316C, YOR328W, YOR363C, YPL039W, YPL040C, YPL099C, YPL107W, YPL134C, YPL138C, and YPL140C.

The base sequences of those yeast genes and the amino acid sequences of the corresponding protein are disclosed in public databases such as MIPS in Germany: Munich Information Center for Protein Sequence, and SGD in USA: Saccharomyces Genome Database, and are known via the internet.

In addition to the yeast genes as described above, genes that are homologous to the yeast genes and are derived from other species may be used in the invention. In this context, “a gene(s) that is (are) homologous to the yeast genes” means genes that comprise a base sequence having a homology of 50% or more, preferably 80% or more to the base sequences of yeast genes, and that encode a protein having the same functions as the proteins encoded by the yeast genes.

Cells as used herein may be either eukaryotic or prokaryotic cells as long as they comprise the genes as described above. Preferred cells are yeast cells.

Methods for detecting mRNA have been previously known, and any one of those methods may be used in the present invention.

As an embodiment of the invention, mRNA is detected through reverse transcription-PCR. Reverse transcription-PCR is well known in the art. See, for example, NAKABEPPU Yusaku, et al.: Cell Technology, suppl. Tips series, Modified PCR Tips, Shujunsha Co. Ltd., 1999, pp 25-43. For example, the invention comprises:

(1) adding a test material to the cell, and incubating the mixture;

(2) extracting mRNA from the cell;

(3) preparing cDNA from the mRNA via reverse transcription using labeled nucleotides; and

(4) hybridizing the cDNA as used as probe with the gene as described above.

Incubation of cells may be conducted using usual media and usual temperatures. Test materials comprising a chemical substance to be tested are added to the medium, and the cells are incubated further for several hours. Concentrations of the test materials are selected to not lead to cell death. Test materials may comprise one or more chemical substances.

For methods of extraction of mRNA, it is well known that a polynucleotide having a poly T structure which is immobilized on the surface of magnetic beads or latex beads is used to trap the mRNA, and then the mRNA is washed and eluted with spine column in view of the fact that a poly A chain is attached to the 3′ terminus of mRNA, which is readily conducted using a commercially available kit such as Oligotex-dT30<Super>mRNA Purification Kit, Takara. The mRNA is reverse-transcribed with a reverse transcriptase (Super Script II Reverse Transcriptase; catalogue No. 18064-014, GibcoBRL) using fluorescence-labeled nucleotides. As such, labeled cDNAs that are introduced with fluorescence-labeled nucleotides during the reverse transcription are obtained. Reverse transcriptases and nucleotides that are labeled with Cy3-dUTP or Cy5-dUTP are also commercially available (for example, Super Script II Reverse Transcriptase; catalogue No. 18064-014, GibcoBRL). Fluorescence-labeled cDNAs are detected with a fluorophotometer.

RT-PCR is a procedure for detection and quantitative determination of an intended RNA in a form of the amplified cDNA, which comprises reverse-transcribing mRNA into cDNA with a reverse transcriptase, and conducting PCR using the cDNA as a starting material as well as specific primer sets and a thermostable DNA polymerase.

In the present step, a microarray containing the gene as described above (DNA tip) may be prepared to hybridize them with the cDNAs, thereby facilitating the efficient detections, which is a preferred embodiment of the present invention.

As another embodiment of the invention, the mRNA is detected by northern blotting. Northern blotting is well-known in the art (OGATA Nobukuni, NOJIMA Hiroshi: Genetic Engineering Keywords Book, revised 2nd ed., Yodosha, co.jp, 2000, pp 299-301). For example, the process comprises

(1) adding a test material to the cell, and incubating the mixture;

(2) extracting mRNA from the cell; and

(3) hybridizing the mRNA with the gene as described above.

Procedures of northern blotting comprises electrophoresing the RNA, transferring the pattern to a filter, and hybridizing it with a specific probe labeled with an isotope, thereby analyzing the presences and the amount of the mRNA in a sample as well as the length of the same.

In the present step, a microarray containing the gene as described above (DNA tip) may be prepared to hybridize them with the cDNAs, thereby facilitating the efficient detections.

In further another embodiment of the present invention, the detection of mRNA is conducted by detecting the production of a polypeptide encoded by the yeast gene as described above. The production of a polypeptide may be detected for example using an antibody directed to the polypeptide.

Toxic substances to be detected according to the present invention include arsenic, cadmium, mercury, 4-nitroquinolin-N-oxide, 2,4,5-trichlorophenol, γ-hexachlorocyclohexane, manganese ethylenebis(dithiocarbamate), 2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile, tetramethylthiuram disulfide, Zinc N,N′-ethylenebis(dithiocarbamate), gingerol, acrolein, and dimethylsulfoxide, all of which are mutagenic.

The following examples are presented for purpose of further illustration of the invention, and such examples are not intended to be limiting the invention in any respect.

EXAMPLES
Example 1

Yeast (Saccharomyces cerevisiae S288C (a SUC2mal mel gap2 CUP1)) were incubated at 25° C. on YPD medium (yeast extract 1%, polypepton 2%, glucose 2%). One of toxic chemical substances was added to the cells at logarithmic growth phase, and the cells were further incubated for two hours. Cells were cultured without any chemical substance in the same condition, and were used as control. Concentrations of the chemical substances were defined to inhibit the growth of the yeast but not lead to death.

Chemical SubstancesConcentrations (1) Na₂As0.3mM (2) CdCl₂0.3mM (3) HgCl₂0.7mM (4) PbCl₂2mM (5) 4-nitroquinolin-N-oxide0.2μM (6) 2,4,5-trichlorophenol16μM (7) γ-hexachlorocyclohexane1.3mM (8) manganese ethylenebis(dithiocarbamate)2ppm (9) 2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile10μM(10) Tetramethylthiuram disulfide75μM(11) zinc N,N′-ethylenebis(dithiocarbamate)2ppm(12) 8-methyl-N-vanillyl-6-nonenamide0.82mM(13) gingerol1.36mM(14) acrolein0.20mM(15) dimethylsulfoxide1.41M(16) Roundup (trademark, herbicide)¹⁾1500-fold dilution(17) sodium dodecylbenzosulfonate0.02%(18) sodium lauryl sulfate0.01%
¹⁾N-(phosphomethyl) glycinate ammonium41.0%, surfactant 59.0%

After completion of the incubation, the culture was centrifuged to collect the cells. To the cells, sodium acetate buffer (50 mM sodium acetate, 10 mM EDTA, 1% SDS) was added, and the mixture was shaken at 65° C. for five minutes, followed by returning to room temperature, and obtaining the supernatant, of which the procedures were repeated two times. To the supernatant, ½ amount of a solution of phenol/chloroform was added, and the mixture was centrifuged to give a supernatant, which was added with an equal amount of chloroform, and the mixture was centrifuged to give a supernatant. To the supernatant, an equal amount of isopropanol containing 0.3 M sodium acetate was added, and the mixture was allowed to stand at room temperature for 30 minutes, after which the mixture was centrifuged to give a sediment of the whole RNAs. Seventy % ethanol was added to the sediment, and the mixture was again centrifuged to give a sediment, which was then dried and dissolved in water. mRNA was isolated from the whole RNAs as followings. In view of the fact that a poly A chain is attached to the 3′ terminus of mRNA, a polynucleotide having a poly T structure which was immobilized on the surface of latex beads was used to trap the mRNA, and then the mRNA was washed and eluted with spine column (Oligotex-dT30<Super>mRNA Purification Kit, Takara). Reverse transcription of the mRNA was conducted with a reverse transcriptase (Super Script II Reverse Transcriptase; catalogue No. 18064-014, GibcoBRL) using fluorescence-labeled nucleotides to give cDNAs that were introduced with Cy3-dUTP or Cy5-dUTP during the reverse transcription.

The labeled cDNAs were dissolved in TE buffer (10 mM Tris-HCl/1 mM EDTA, pH8.0), and the solution was dropped on the DNA chip containing the whole genes of yeast (DNA Chip Research Inc. Japan) so that the cDNAs were hybridized on the DNA chip at 65° C. for over 12 hours. The fluoresces intensity of the DNA chip was read with a scanner, and the ratio relative to the fluorescence intensity resulting from the absence of chemical substance was estimated as the following, which is shown in Tables 1 to 9:
$\frac{The level of expressed mRNA in the presence of chemical substance}{The level of expressed mRNA in the absence of chemical substance}$

TABLE 1Unknown protein yeast genesThe level of expressed mRNA in the presence of chemical substance/The level of expressed mRNA in the absence ofchemical substanceyeast genes(1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)IntensityYCR102C3.43.22.41.10.70.41.14.99.861.513.50.51.14.10.91.21.11.20.53YDL218W3.51.22.61.40.70.91.11.572.512.65.70.91.14.81.13.51.10.90.42YDR533C3.44.93.51.81.32.21.75.47.312.77.71.43.02.92.56.72.32.71.82YGR110W1.63.12.25.90.90.91.71.56.44.80.51.43.62.81.217.10.92.10.19YKL071W8.33.85.42.81.118.63.724.7162.2109.240.31.08.421.91.72.21.00.90.31YLR460C2.12.12.01.11.30.61.18.113.931.614.30.40.73.50.71.81.01.10.48YMR090W6.99.52.33.50.73.82.73.916.76.18.82.26.96.51.95.11.82.81.30YOL150C4.13.79.90.91.05.22.43.710.88.39.42.98.95.71.83.12.72.20.47YBL048W2.07.92.32.81.32.01.91.27.24.42.01.22.72.04.15.71.31.00.29YBL107C1.41.10.41.51.21.12.11.91.03.12.91.42.62.51.41.50.91.41.03YFL024C1.01.11.10.71.12.03.30.90.50.50.60.80.93.30.91.10.90.80.37YGL121C2.65.01.44.20.99.84.73.07.015.06.11.67.85.81.68.52.73.50.60YHR029C2.81.81.81.81.02.72.02.713.68.63.81.54.73.51.01.02.12.10.87YHR209W2.81.10.84.51.83.25.02.02.96.43.31.02.02.25.03.52.62.60.56YKL107W2.42.50.50.81.12.01.10.928.28.32.01.01.93.41.73.51.60.90.17YKR075C1.50.72.74.51.21.51.42.00.20.61.32.33.82.70.44.32.41.91.15YLL056C2.12.33.02.01.10.61.01.358.88.81.71.36.811.01.54.85.32.50.32YLR297W2.42.13.51.71.30.81.11.32.15.53.50.80.82.30.71.80.71.00.81YOR338W1.81.80.51.71.62.61.32.20.63.50.81.21.42.51.81.01.10.50.52YOR391C2.12.00.91.21.31.62.02.818.818.13.21.12.32.45.82.21.00.90.22YPL280W1.71.91.92.01.41.91.82.349.814.01.90.92.42.44.31.51.20.90.22YLR346C4.42.02.14.51.45.55.61.38.66.60.54.26.22.21.02.410.67.80.53YOR049C2.50.912.81.41.38.44.20.91.11.91.16.77.11.51.34.32.62.90.22YAL034C1.11.82.81.11.01.51.81.03.03.31.52.84.91.21.41.01.21.30.52YDR476C0.71.86.01.20.53.11.51.31.73.41.62.12.81.12.22.02.41.50.58YGR035C1.60.61.20.61.33.31.10.91.10.50.43.32.10.80.31.92.54.31.04YGR284C1.02.04.01.41.21.42.21.14.31.81.72.13.61.23.91.91.32.12.57YHR054C1.70.92.21.01.02.91.61.82.67.70.93.65.81.00.82.25.13.40.80YLR008C0.90.50.70.91.32.72.01.00.40.70.83.56.21.60.71.75.44.92.00YMR315W4.31.81.74.22.92.02.42.63.22.02.51.32.51.62.12.81.76YNL211C1.21.00.81.01.07.43.11.10.81.11.13.29.91.10.89.34.26.80.52YOL031C0.91.91.01.71.21.02.52.12.31.41.32.12.41.14.41.51.21.91.20YOL101C0.90.80.41.71.60.50.70.90.10.30.92.40.20.80.63.50.60.61.37YAR031W1.51.11.11.71.12.91.61.22.71.61.41.23.31.40.93.51.62.51.00YBL049W2.911.82.12.91.11.71.95.25.22.20.73.91.57.26.41.11.10.47YBR062C1.31.70.41.21.41.91.51.95.42.22.31.22.82.60.72.21.41.60.93YCR013C1.31.45.01.11.11.81.60.70.81.32.41.43.91.51.61.61.11.32.80YDL027C1.22.01.71.71.22.12.91.52.02.31.71.73.21.11.41.81.42.00.69YDL110C1.51.41.12.10.81.72.51.83.02.31.91.52.72.71.33.62.04.41.27YDL169C1.71.71.11.31.12.62.11.37.34.71.21.23.72.72.23.81.51.60.42YDR070C2.26.43.63.50.96.21.41.913.96.04.14.36.62.02.115.11.23.10.44YDR210W1.11.00.91.02.01.21.51.40.51.01.01.02.31.11.01.51.91.91.82YDR214W1.34.04.51.31.11.71.51.55.52.41.91.15.31.21.10.71.21.01.07YDR435C1.21.11.21.41.22.52.11.20.82.11.31.12.51.30.62.01.32.01.30YER037W2.02.10.81.11.33.22.61.01.05.51.51.23.01.70.81.81.72.61.17YFL044C1.01.50.82.31.61.31.61.45.23.72.21.24.71.21.01.81.31.40.50YFR003C1.21.50.81.61.02.21.41.48.33.11.40.92.52.11.01.41.31.81.01YFR020W1.00.91.21.00.91.41.10.93.73.51.40.92.31.82.61.01.20.90.61YFR044C0.91.33.81.10.92.11.20.82.12.21.91.23.10.81.51.21.01.01.99YGR010W1.21.60.91.20.81.21.71.613.68.91.50.95.21.91.31.40.81.30.55YGR142W2.76.215.31.31.30.91.41.536.812.22.32.08.90.91.30.31.91.51.28YGR161C2.02.25.43.81.01.41.41.32.03.80.81.72.80.91.71.11.51.80.65YGR212W1.51.71.51.31.21.01.13.80.91.510.01.11.12.13.92.20.28YGR268C1.12.32.02.51.11.11.01.14.11.60.81.02.81.01.51.21.51.40.48YHR016C0.81.51.71.51.83.70.82.82.02.21.33.30.90.62.11.21.40.51YHR087W1.22.78.62.80.74.23.41.24.13.93.71.44.01.51.93.81.22.91.34YJL048C1.72.52.02.90.91.50.71.51.23.83.21.12.41.70.62.31.62.50.82YJL144W1.91.62.21.61.21.71.71.314.68.93.00.83.91.61.02.52.22.40.60YJL163C1.21.91.71.50.92.82.30.714.52.53.12.04.51.02.02.81.51.70.28YJR074W1.01.42.02.00.71.21.81.33.73.11.22.02.81.73.41.51.81.90.68YKL065C1.92.01.31.71.02.33.81.83.13.91.31.33.02.11.72.82.84.62.29YKR011C1.11.60.91.61.22.32.72.04.74.41.51.13.51.41.81.31.31.90.66YKR018C0.71.11.70.70.91.71.00.73.91.71.41.03.01.11.01.81.01.20.98YKR046C1.97.82.81.80.61.91.30.83.92.02.61.32.81.92.93.51.21.90.73YKR049C1.64.21.03.20.93.02.41.32.23.22.21.24.12.10.94.21.63.31.17YLR132C1.01.10.31.11.21.11.10.74.52.50.51.02.71.32.31.61.21.60.36YLR161W0.90.80.80.70.91.21.30.81.01.51.50.82.11.00.61.11.10.90.33YLR217W0.92.02.10.71.41.41.51.03.28.20.93.80.90.90.81.01.20.35YLR328W1.31.21.30.90.94.85.41.10.91.21.41.24.30.50.81.41.10.81.04YML128C1.53.34.14.10.55.12.81.15.13.12.91.44.91.42.65.62.05.51.66YMR040W3.12.90.92.81.72.85.11.71.41.41.52.15.21.82.02.73.13.70.62YMR251W1.31.31.80.62.21.63.11.73.111.62.81.22.51.50.41.31.50.90.20YMR322C2.04.31.52.91.41.81.72.121.310.33.21.12.12.73.61.81.40.80.18YNL094W0.91.41.11.01.42.91.22.03.52.61.71.23.41.01.51.51.11.30.66YNL134C2.36.04.50.91.71.41.53.26.15.95.01.13.11.40.82.11.32.02.51YNL155W1.11.21.10.91.43.01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133C0.91.12.92.01.20.70.20.50.10.41.30.30.10.60.61.10.60.94.02YGR038W0.91.23.50.81.31.31.10.71.41.01.41.01.21.41.11.31.11.11.27YGR243W1.42.29.45.01.01.51.91.30.73.01.71.21.11.90.82.82.14.41.11YHR105W0.90.82.46.31.50.20.91.01.13.40.70.71.41.20.91.81.00.90.32YHR181W0.90.72.41.41.00.90.80.90.51.31.30.80.71.61.41.50.90.91.40YJL097W1.01.13.71.60.91.61.00.80.30.71.51.00.71.01.11.21.21.11.69YKL051W1.01.14.70.80.81.00.60.81.31.11.80.81.20.71.50.91.51.41.07YKL100C0.71.15.01.60.61.81.20.71.31.31.60.91.31.01.72.00.71.51.14YLR339C0.70.83.10.81.30.40.40.50.41.60.60.10.51.00.50.70.61.37YOL030W1.00.84.41.00.90.91.30.61.20.61.30.91.70.60.90.70.91.01.93YPR150W1.31.14.33.01.30.90.90.81.23.30.90.61.41.40.91.80.91.00.31YBL100C0.81.81.60.50.60.41.10.60.20.80.90.70.90.91.00.50.80.80.58YBR096W1.11.52.81.60.91.71.91.01.21.61.20.91.91.71.11.11.11.51.43YBR100W1.01.54.81.10.90.51.00.98.53.00.20.71.21.21.31.20.80.90.35YCL058C1.11.62.21.21.71.10.80.90.61.01.01.00.91.91.20.81.40.90.72YCR030C1.10.93.31.01.01.21.00.70.92.01.10.91.70.81.31.01.21.00.63YDL015C0.90.73.61.11.22.51.10.90.71.10.81.00.91.11.12.11.01.52.99YDL023C0.81.62.41.10.60.31.50.70.71.53.50.91.40.70.60.90.81.10.78YDL086W0.91.21.90.91.30.90.80.81.31.11.40.81.70.90.91.10.80.80.80YDR233C1.11.13.21.90.70.81.21.10.20.73.71.30.50.91.52.80.90.93.47YDR359C0.80.71.71.91.30.81.00.80.71.00.51.01.11.31.40.90.80.90.34YEL033W0.91.22.71.11.00.70.30.70.60.41.20.60.41.00.60.90.90.92.96YGR022C1.31.11.72.21.11.30.90.90.20.40.71.21.10.70.60.90.80.50YGR026W0.81.12.90.90.91.50.90.90.80.71.30.50.61.01.21.41.01.22.19YGR107W1.00.81.70.91.10.81.00.90.10.00.60.60.91.01.10.81.20.80.43YHL005C0.92.72.70.21.21.10.80.90.90.70.71.00.70.71.00.80.33YHR126C1.10.92.80.61.01.21.10.60.40.71.91.00.80.81.41.71.11.31.31YHR143W0.50.94.91.01.22.10.51.50.20.71.20.50.50.80.30.90.90.73.58YIL157C1.11.32.11.70.81.31.21.00.90.91.30.81.01.00.51.81.11.51.46YIR041W1.61.02.41.41.31.01.60.91.52.51.21.31.11.11.31.31.10.90.66YJL016W1.31.62.71.31.41.51.40.90.60.91.30.91.31.61.12.51.21.50.88YJR018W0.81.21.80.71.11.00.90.70.40.70.90.81.50.91.40.81.00.70.35YKL147C1.01.31.90.90.80.70.80.71.00.50.30.91.01.00.71.10.90.90.28YKL169C1.01.01.61.80.81.21.51.20.30.50.71.01.30.82.60.91.10.45YKR033C0.91.22.11.01.00.61.01.00.11.40.30.40.90.91.10.61.00.90.28YLL064C0.81.71.71.90.91.71.10.91.12.51.01.11.31.11.21.61.21.00.68YLR041W0.81.22.21.51.60.51.20.60.41.10.40.30.51.30.50.70.90.69YLR177W0.81.21.82.20.81.11.30.91.02.30.91.11.51.00.51.31.11.51.25YMR007W1.10.92.00.71.31.73.10.70.10.90.81.31.21.81.12.51.00.30YMR156C1.00.92.71.71.21.41.40.90.61.31.10.71.01.20.71.31.21.10.40YMR215W0.80.52.11.21.10.30.30.50.10.21.10.40.20.50.70.20.70.71.59YNL195C0.91.13.54.70.90.81.10.92.611.72.90.61.61.51.46.40.80.90.32YOL073C0.70.92.50.61.11.21.30.71.91.11.70.81.60.81.61.71.21.20.54YOR129C0.60.83.30.81.30.40.40.60.20.41.10.60.20.50.60.30.60.45.22YOR161C0.61.06.02.21.10.91.20.81.01.74.60.50.70.91.42.00.71.20.82YPL004C0.71.23.71.91.41.32.30.91.11.61.70.91.31.01.12.01.22.24.52YPL246C0.70.82.60.91.41.30.80.60.40.51.10.80.90.71.21.11.20.90.98YPL272C1.10.92.20.61.31.10.70.81.22.51.10.71.11.10.62.50.91.20.25YPR063C1.00.82.60.81.21.00.60.70.50.61.00.70.81.01.01.21.00.91.41YDL129W1.00.71.02.31.30.90.91.00.50.90.60.90.50.80.51.40.60.80.69YDR066C1.31.50.92.21.01.41.11.31.51.10.60.81.41.30.91.41.11.10.57YGL059W1.31.50.93.10.70.71.01.41.61.71.41.02.01.21.61.71.41.40.49YNL144C1.80.81.24.50.91.11.11.10.71.91.71.41.01.10.11.72.42.80.51YAL037W1.60.91.13.51.21.11.01.30.61.90.50.81.11.20.80.60.90.90.55YAR023C1.11.01.72.11.31.01.10.80.91.41.01.21.11.03.11.60.91.10.62YCR015C1.10.90.52.11.71.01.51.20.51.01.10.90.61.20.91.11.11.20.58YCR043C1.40.50.82.30.90.80.71.20.30.71.00.60.81.61.20.81.01.11.25YDL146W1.01.21.22.00.70.71.40.90.82.31.41.01.41.01.71.81.01.20.62YDR057W0.91.41.62.60.80.71.41.21.51.11.00.70.91.21.11.70.71.10.70YDR222W1.01.11.71.71.41.30.51.00.61.01.00.50.81.30.50.60.70.80.52YDR286C1.60.91.12.11.01.71.31.90.81.21.10.91.41.30.82.11.11.40.90YDR438W1.21.80.82.11.61.31.41.01.10.81.10.81.21.31.01.21.61.20.48YDR479C1.11.81.02.30.91.61.20.91.21.61.01.01.21.41.62.11.11.50.51YEL057C1.10.61.32.41.00.91.11.21.21.90.70.81.51.51.01.80.91.00.44YEL073C1.60.81.02.81.21.50.80.90.71.21.10.51.01.12.81.01.30.80.38YER084W0.81.11.03.90.90.60.80.90.80.80.70.92.61.50.80.90.30YER121W1.11.20.77.71.32.51.31.30.60.51.20.70.61.30.94.61.21.80.73YER189W0.90.80.91.91.30.50.90.70.40.50.70.80.70.90.90.80.80.80.43YFL017C1.31.20.92.31.51.31.51.40.80.61.11.00.71.10.61.81.51.81.21YFL046W1.30.90.72.11.70.71.31.30.70.71.30.80.71.31.01.11.41.60.68YFR008W1.11.00.82.21.11.01.10.91.51.40.70.90.81.10.81.51.01.01.26YGL214W0.91.01.22.61.20.90.80.90.40.70.40.80.61.10.90.81.00.80.61YGL218W1.40.91.43.41.21.10.81.11.30.40.10.81.30.91.10.71.01.00.53YGR021W0.91.51.08.61.00.91.31.40.70.60.60.90.91.20.82.11.01.00.58YGR024C1.20.90.72.61.00.71.31.40.41.21.00.70.51.41.01.20.81.31.61YGR064W1.11.21.62.30.70.61.11.00.10.81.70.80.92.11.01.30.80.90.50YGR182C1.61.21.22.31.10.90.71.10.50.70.90.70.72.20.42.01.01.71.95YGR236C1.61.60.44.11.21.21.01.21.50.71.00.91.21.20.77.91.51.90.30YHL042W1.20.81.351.11.00.71.21.00.81.80.70.61.31.21.11.91.10.90.37YIL012W1.25.81.52.81.51.50.90.91.72.80.90.60.41.11.10.91.00.90.28YIL028W1.01.10.85.41.40.71.10.80.81.71.10.51.01.10.91.11.31.00.27YIL057C1.31.81.14.61.31.21.21.40.15.00.80.60.91.50.811.11.13.60.26YIL089W1.31.30.73.91.61.61.61.10.60.70.60.71.40.61.31.41.30.31YIL102C1.41.61.06.11.50.81.10.70.30.60.71.00.80.61.21.00.18YIL113W0.91.00.92.60.61.01.90.71.92.22.50.81.31.20.91.61.41.30.48YIL122W1.21.11.12.10.90.20.80.70.40.82.11.00.71.01.61.40.90.90.35YJL100W1.42.00.92.31.31.11.21.21.82.71.50.91.41.21.21.41.51.10.38YJL169W0.81.11.52.81.40.80.90.70.30.50.40.50.71.00.90.61.10.90.35YJL199C1.10.70.94.51.01.71.01.01.01.61.00.80.91.90.93.71.01.00.59YJR039W0.90.60.83.01.81.01.61.21.81.61.80.71.50.61.21.51.31.30.24YJR101W0.80.60.72.91.80.91.51.10.40.81.20.50.50.90.51.21.01.12.04YKL061W1.30.70.71.80.81.00.91.20.81.01.10.70.81.20.61.51.31.60.92YKL121W0.97.80.811.81.61.21.71.00.80.91.60.81.01.20.81.61.61.10.31YKL160W1.51.00.41.81.11.51.52.11.31.91.40.91.61.50.81.61.52.22.19YLR016C0.71.30.52.01.50.81.11.20.81.11.00.70.80.90.71.31.01.31.15YLR030W1.41.50.82.51.21.51.50.90.32.70.20.81.51.20.62.11.01.00.29YLR036C1.30.80.72.01.51.31.71.20.41.60.80.70.71.30.61.41.01.41.07YLR112W1.10.91.11.71.31.31.00.70.70.50.50.70.80.40.41.00.80.39YLR125W1.42.00.53.11.80.71.31.20.51.71.10.50.81.30.71.61.21.20.29YLR128W1.31.40.81.81.31.31.10.81.71.40.71.21.40.91.51.21.20.25YLR204W1.10.90.52.12.01.52.01.31.41.61.60.81.11.81.02.51.21.31.26YLR211C1.31.00.87.71.71.21.81.10.91.20.80.71.11.23.61.91.31.30.35YLR257W1.51.00.72.41.41.20.81.31.01.11.21.01.00.91.01.71.82.65.20YLR326W1.21.01.52.21.30.41.20.90.71.56.60.50.41.10.70.90.81.00.33YLR334C1.21.11.12.31.81.01.40.91.00.80.80.80.92.22.50.70.81.00.30YLR408C1.32.30.62.31.41.01.01.40.91.10.70.81.12.10.91.11.21.20.79YLR414C1.51.61.44.81.30.60.70.90.21.21.20.61.01.02.10.93.93.62.21YLR444C0.90.81.75.90.70.70.90.90.20.21.10.60.51.11.30.70.90.90.50YML050W1.51.21.32.10.80.50.91.11.31.61.20.80.91.91.01.50.81.10.42YML107C1.10.70.41.82.21.11.51.30.60.90.90.70.61.31.01.31.21.50.67YMR031C0.70.81.22.10.60.70.80.91.51.10.80.71.01.00.71.60.91.31.26YMR204C1.11.91.32.31.00.60.71.01.02.20.70.71.11.21.51.10.91.10.31YMR206W1.41.42.33.91.11.01.30.91.09.01.81.01.21.40.32.21.01.20.17YNL010W1.51.00.71.91.01.21.11.80.50.61.10.90.71.20.91.21.01.74.53YNL127W1.11.20.73.60.71.20.81.02.72.21.01.01.71.01.51.40.91.40.36YNL217W1.11.20.51.72.11.51.31.40.30.90.71.01.00.90.51.01.32.12.35YOL118C2.62.21.32.21.53.21.13.21.40.61.73.01.00.50.91.00.24YOR053W1.01.10.51.71.70.91.60.91.30.81.30.60.91.21.01.31.21.20.77YOR352W1.30.91.02.21.60.91.81.11.72.01.11.01.21.30.72.51.31.70.59YOR394W1.20.82.21.61.61.71.81.01.12.31.90.91.30.90.91.71.61.10.51YPL033C0.81.00.95.11.30.71.00.70.41.60.70.60.71.10.80.40.90.80.23YPL066W0.91.01.12.01.31.31.30.90.50.81.01.10.90.70.71.21.31.30.77YPR014C1.00.71.17.90.80.90.80.90.90.50.70.71.00.90.80.91.10.29YBR005W1.92.61.12.90.80.71.20.90.41.30.81.71.90.91.11.72.94.61.00YFL027C0.80.81.11.31.10.30.41.11.81.31.30.61.10.31.41.25.15.21.74YGL080W1.31.51.11.31.51.41.51.21.11.20.81.00.71.60.91.71.32.91.70YMR252C1.11.01.51.31.31.01.31.10.91.01.40.81.11.11.12.11.52.20.86YOR385W2.81.20.22.51.51.01.21.01.52.21.20.62.80.80.81.24.65.91.17YAR033W1.00.81.51.11.11.42.11.21.31.61.50.91.51.30.92.01.13.01.15YBR151W0.80.81.31.21.21.71.30.80.80.90.90.91.10.81.03.01.42.41.83YHR162W1.21.20.91.81.21.31.71.41.01.71.31.21.52.01.11.41.32.73.64YLR165C1.40.81.31.11.11.51.41.11.71.01.40.91.21.40.51.61.12.10.78YNL157W1.41.10.71.51.90.91.31.11.71.41.30.91.61.51.01.01.92.31.41YOL002C0.90.70.51.02.00.90.40.80.10.30.81.10.20.50.61.71.52.15.33YPL233W1.20.90.51.11.40.61.01.00.30.60.90.61.01.00.41.01.91.90.48YGR149W1.41.31.81.91.01.71.80.80.60.61.81.22.61.02.41.32.01.70.71YNL043C1.04.41.61.30.80.60.90.90.40.40.70.92.11.21.60.82.71.60.68YPL067C1.21.62.81.41.00.81.21.20.80.91.40.90.71.51.12.91.70.40YPL170W1.21.30.91.11.91.10.61.11.41.01.10.91.11.41.21.62.21.41.05YGL051W1.11.01.61.71.31.01.30.81.11.81.41.01.51.20.82.61.41.91.06YIL112W1.11.42.81.90.61.31.10.91.32.01.41.21.11.31.82.41.21.30.45YLR052W1.01.50.81.31.00.81.01.20.41.11.11.00.81.21.02.40.70.90.77YNL203C0.91.30.33.21.01.71.60.80.31.10.91.22.71.25.61.31.70.21YNR014W1.00.81.71.21.20.71.70.90.32.34.40.91.54.91.02.41.11.00.31YAL028W0.90.71.12.01.00.61.20.81.61.31.01.01.51.62.21.71.01.00.30YBL095W0.81.41.21.41.10.91.10.91.00.61.20.81.01.00.42.21.31.90.72YBR157C0.71.00.41.41.31.21.60.70.60.30.60.60.50.90.21.91.30.80.69YDL091C1.11.31.81.40.70.81.31.31.61.51.51.01.31.51.92.41.11.60.47YDL216C1.11.10.72.01.61.61.21.61.31.30.70.91.21.11.01.81.01.60.42YDR067C1.31.20.72.70.91.11.31.81.01.30.90.91.21.51.52.41.31.40.76YDR186C0.70.90.70.71.30.71.41.21.21.60.71.11.10.80.82.31.10.90.50YDR196C0.90.90.71.11.01.71.71.51.61.11.30.71.21.00.72.71.21.91.54YDR262W1.31.80.81.21.71.31.71.20.91.71.60.80.91.71.53.81.01.41.11YDR306C0.91.20.71.81.71.21.61.32.01.42.10.91.21.11.22.41.01.50.77YDR319C1.30.90.81.11.21.21.71.31.11.11.31.01.30.82.02.12.21.23YER188W1.30.91.21.90.91.51.20.70.40.91.20.91.11.10.32.51.01.10.61YGL004C0.81.41.31.01.01.42.91.41.82.21.00.81.30.90.62.21.11.40.48YGR141W0.81.61.61.71.11.51.50.90.31.00.60.61.00.72.62.11.11.30.65YHR080C0.61.81.90.70.81.81.11.11.91.20.71.22.00.90.92.31.11.30.49YHR097C1.60.70.70.90.80.80.70.40.60.70.81.30.92.72.01.71.40.24YIL077C0.90.81.21.21.31.81.20.91.51.41.31.61.31.30.92.41.31.10.75YJL046W0.90.90.61.81.00.71.51.11.82.74.20.91.31.31.02.51.01.30.68YLL005C1.01.11.11.21.61.91.31.00.41.00.90.81.11.71.02.11.11.20.44YLR151C1.42.01.41.01.01.41.41.50.91.10.50.71.30.72.41.01.40.30YLR271W1.61.20.81.81.41.41.71.51.01.01.30.81.21.21.03.01.51.80.78YMR025W1.21.20.71.51.31.31.41.21.01.61.20.91.21.81.12.41.01.50.42YMR135C1.01.01.11.91.81.01.01.01.11.41.11.01.31.01.42.31.51.31.06YMR210W1.01.11.81.90.60.81.11.11.52.20.80.91.01.01.02.20.81.50.56YNR040W0.84.90.50.90.91.62.11.31.10.81.20.60.81.50.72.11.11.00.30YPL039W1.20.90.61.31.41.51.51.41.11.00.90.91.11.10.62.41.11.10.52YPL099C1.11.90.72.00.91.21.41.42.41.70.80.91.11.30.52.11.01.70.92YPL107W1.20.81.11.31.01.11.21.51.41.31.10.70.81.70.71.81.01.10.59YPL138C1.11.71.11.80.70.51.11.31.11.50.50.90.61.32.72.60.81.10.38

TABLE 2

Mitochondria-located protein genes

The level of expressed mRNA in the presence of chemical substance/The level of expressed mRNA in the absence of

chemical substance

yeast genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity

YJR048W
1.3
0.9
2.2
1.4
0.8
0.5
0.3
0.9
0.5
1.5
1.0
0.8
0.4
2.5
0.6
1.5
1.2
1.2
1.19

YOR226C
1.3
2.2
1.7
1.1
1.3
1.2
1.2
1.2
1.3
5.9
1.5
0.6
0.9
2.7
1.0
0.7
1.0
0.7
0.58

YDL174C
0.9
1.8
0.9
1.3
0.5
1.7
3.6
0.8
0.5
1.7
0.9
2.8
5.9
1.1
0.6
5.1
2.2
4.0
0.63

YBL022C
0.4
0.8
1.2
0.7
1.2
1.2
1.0
0.4
2.8
1.2
1.1
0.9
2.6
1.0
1.5
1.0
0.9
0.7
0.76

YCL057W
0.6
1.5
2.3
0.5
1.1
1.8
1.4
1.8
4.2
2.1
1.6
1.0
3.8
1.0
2.8
1.5
0.9
1.1
0.76

YDR258C
1.6
2.3
2.8
1.4
1.3
2.4
3.9
1.9
4.9
13.3
1.7
1.8
5.2
1.5
0.6
1.0
1.3
1.3
0.87

YGR028W
1.4
3.5
1.0
1.8
0.9
1.5
2.1
1.4
1.7
2.0
1.1
1.5
2.6
1.2
1.0
2.2
1.5
2.6
0.91

YGR244C
1.0
1.2
1.6
1.6
0.8
2.6
3.9
1.8
1.4
1.1
1.8
1.9
2.6
1.2
2.0
2.6
1.9
3.1
1.12

YKL142W
1.8
2.7
3.1
1.4
0.7
3.4
6.9
2.3
5.8
5.9
2.0
1.9
3.3
2.3
1.3
3.3
2.4
3.6
1.68

YNL055C
1.1
1.8
5.5
2.0
0.9
2.6
1.2
0.7
1.1
1.0
1.9
1.7
2.4
0.9
1.1
2.6
1.2
1.7
4.10

YNL071W
0.9
0.9
1.7
1.5
0.6
1.3
1.4
0.9
1.1
1.2
1.6
1.3
2.5
0.8
1.1
1.1
1.0
1.2
1.61

YOR020C
1.4
2.1
1.7
1.7
1.5
2.3
1.7
1.7
5.8
2.6
2.5
0.8
3.0
1.6
1.5
1.4
1.4
1.7
1.66

YOR037W
1.0
1.5
0.6
1.4
1.5
1.6
2.5
1.5
1.3
1.0
1.2
1.2
2.1
1.0
0.9
1.4
1.2
1.6
0.61

YDL198C
1.4
1.0
2.1
1.4
0.7
0.8
1.0
1.1
1.9
2.7
2.5
1.2
2.0
1.7
1.2
1.4
1.5
1.1
1.19

YDR231C
1.1
1.6
1.0
1.5
1.1
2.2
1.7
1.3
1.5
1.4
1.3
1.1
2.4
1.5
1.0
3.0
1.2
1.3
0.92

YER178W
0.8
0.9
3.6
1.0
0.7
2.5
1.6
0.8
1.7
1.3
2.5
1.3
2.4
0.9
1.8
1.0
1.1
0.9
2.18

YFL016C
0.8
1.0
1.6
0.9
1.3
1.3
1.4
0.7
6.4
2.9
1.2
1.0
2.8
0.8
0.8
0.6
1.2
0.9
1.25

YGR008C
2.1
3.0
1.7
3.2
0.9
2.9
3.7
1.9
3.1
2.4
2.6
2.0
3.4
1.3
1.5
2.3
1.7
4.2
3.03

YIL155C
1.0
0.7
1.4
3.7
1.3
1.4
2.2
1.0
2.5
2.9
1.3
1.4
2.0
1.3
1.4
3.8
1.1
1.4
0.51

YJL102W
1.1
0.7
0.4
0.8
1.3
1.6
0.6
0.9
3.1
2.2
0.7
0.8
2.6
1.5
1.5
0.6
1.0
1.1
0.22

YJR045C
0.5
1.9
3.9

0.5
1.2
1.0
0.8
3.2
3.0
1.4
1.0
2.3
0.5
2.3
0.8
0.7
0.9
3.78

YLR259C
0.7
1.0
3.1
1.6
1.1
0.9
1.8
0.8
1.8
2.6
3.0
0.7
2.5
0.8
2.1
1.3
0.8
1.0
2.09

YLR348C
1.1
4.5
1.2
1.2
0.9
1.9
0.9
0.9
2.1
1.3
1.3
0.9
1.9
1.0
2.4
1.1
1.1
1.0
0.64

YML054C
1.5
1.8
1.3
3.4
1.3
1.8
1.2
1.5
4.1
1.8
1.4
1.8
2.8
2.1
1.1
7.8
1.1
1.6
0.25

YMR089C
0.8
1.1
0.9
0.9
0.8
1.2
1.2
1.3
5.6
2.5
1.3
0.8
2.3
0.9
1.8
1.1
0.9
1.1
0.69

YMR152W
0.9
1.1
1.8
0.9
0.8
7.5
0.8
0.8
2.7
1.3
1.2
1.3
1.9
1.1
0.6
1.0
1.5
0.9
0.71

YNL104C
1.1
1.3
3.0
0.9
0.8
0.8
0.6
0.9
1.1
2.0
2.1
1.1
2.1
0.9
2.5
1.5
0.9
0.9
1.69

YOR130C
0.8
1.7
1.4
1.0
1.8
1.6
1.3
0.8
2.0
1.7
0.6
0.9
2.1
1.3
1.0
0.8
1.5
1.1
0.51

YPR024W
0.7
1.0
1.3
1.0
1.3
1.0
1.4
0.7
3.0
1.7
0.9
0.8
2.5
0.7
1.0
1.6
1.1
0.8
0.84

YPR067W
1.6
1.2
1.7
0.9
1.3
1.3
1.5
1.4
3.5
3.4
1.8
1.0
3.0
1.6
1.3
0.8
1.0
1.0
0.66

YBR029C
0.7
0.2
1.8
1.0
1.4
0.8
0.4
0.7
2.0
1.1
0.7
1.3
1.7
0.9
3.5
0.9
0.6
0.8
1.56

YCL009C
0.6
0.9
2.0
0.5
0.7
1.8
1.3
1.1
0.9
1.6
1.5
1.7
1.6
0.7
6.5
0.9
1.1
0.8
0.68

YER026C
0.8
0.6
3.3
1.0
1.2
2.5
1.6
0.8
0.9
1.5
0.9
1.7
1.9
1.1
4.0
1.4
1.7
3.2
4.48

YLR109W
0.8
2.9
6.0
0.9
1.3
2.1
2.6
0.9
2.4
2.7
1.5
1.6
3.2
2.3
3.9
1.8
1.1
1.2
3.86

YMR189W
0.7
0.8
1.9
2.8
0.4
1.9
0.8
0.4
0.7
0.9
8.2
0.6
0.9
1.6
5.6
0.9
1.0
0.8
0.88

YNL169C
0.7
1.4
1.4
1.2
0.7
1.4
0.7
0.8
1.1
1.1
0.8
1.0
1.7
0.9
3.4
0.8
1.1
1.3
1.05

YER069W
1.3
0.8
3.3
1.4
1.5
1.3
1.0
1.5
0.8
10.4
1.5
0.8
1.4
1.3
2.4
1.1
1.1
0.9
0.25

YIL022W
0.8
0.7
1.1
1.6
0.8
1.2
0.7
0.8
1.1
1.3
1.0
0.9
1.2
0.6
2.9
1.1
0.8
0.7
0.52

YBR146W
0.9
0.8
0.7
1.5
1.3
2.6
1.5
1.0
0.9
1.1
1.2
1.0
1.7
1.2
1.0
2.9
1.0
1.2
1.61

YDR019C
1.4
0.5
1.7
4.0
0.9
4.8
1.4
0.7
0.4
0.7
1.8
0.7
1.0
1.6
1.8
1.8
1.2
1.6
2.48

YGR207C
1.5
1.1
1.0
1.1
1.5
2.8
1.7
1.9
2.1
2.6
1.4
1.1
1.0
2.2
0.6
1.8
1.2
1.8
1.49

YMR072W
1.1
1.0
1.4
1.0
1.7
2.4
1.4
1.0
3.0
1.2
1.9
0.8
2.1
1.2
0.8
1.7
0.9
1.9
2.06

YNL037C
1.4
1.8
1.7
1.1
1.7
2.8
2.8
1.0
0.6
3.2
1.4
1.3
1.9
1.3
0.9
1.4
0.9
1.3
2.05

YOR136W
1.0
0.9
3.5
1.0
1.5
3.9
3.2
1.1
0.3
3.4
1.4
1.2
1.5
0.9
1.2
1.3
0.8
1.3
3.20

YPL271W
1.2
3.2
4.1
1.2
1.4
3.3
1.2
0.9
0.6
1.2
1.7
0.8
1.2
1.3
0.8
1.4
1.2
1.3
1.34

YAL044C
1.5
1.1
1.0
3.0
0.8
2.2
1.0
0.8
0.4
0.6
1.4
0.6
1.1
1.4
0.7
1.0
1.4
1.8
4.07

YAL054C
1.2
1.1
1.4
1.6
1.1
2.2
1.1
1.1
8.9
4.1
1.3
1.0
1.8
1.3
0.9
2.5
1.5
1.4
0.24

YBR024W
1.0
1.0
1.1
2.4
1.0
2.2
1.9
1.4
1.3
1.4
1.3
1.1
1.7
1.9
0.8
2.3
1.0
1.2
1.14

YDR405W
0.9
1.1
4.7
1.0
1.1
2.4
1.2
0.9
0.6
1.0
1.0
1.2
1.3
1.1
2.5
1.3
1.3
0.9
0.44

YGL068W
1.0
0.6
1.1
1.4
0.9
2.6
1.5
0.9
0.7
0.8
1.0
1.1
1.0
0.9
0.6
1.8
1.8
1.0
3.35

YGR220C
1.1
0.6
0.9
1.1
1.3
2.1
1.4
1.5
0.8
1.5
1.1
0.9
1.1
1.5
1.1
2.3
0.9
1.1
1.42

YHR037W
0.7
0.9
1.3
1.6
0.9
1.8
1.2
1.0
0.9
2.2
1.7
1.1
1.1
1.1
1.1
2.0
1.0
1.4
1.15

YIL070C
1.2
1.0
0.8
1.4
1.3
2.3
1.6
1.1
0.3
0.6
1.0
0.8
0.7
1.3
1.0
2.4
0.7
1.1
1.69

YIL111W
1.6
1.0
1.8
2.7

2.6
3.2
1.2
1.6
1.1
2.1
0.9
1.7
1.5
1.1
2.5
1.9
3.9
1.52

YKL138C
1.2
0.9
0.6
0.9
1.3
2.3
1.9
1.7
1.1
2.1
1.2
0.8
0.8
1.6
0.6
2.5
1.0
1.3
1.29

YKL150W
1.1
2.0
3.0
1.4
1.4
2.3
2.4
1.3
1.1
1.3
1.9
1.2
1.8
1.4
0.9
6.1
1.2
2.7
2.20

YKR006C
1.0
0.7
1.2
1.2
1.4
2.4
1.6
1.2
1.0
1.5
1.2
0.8
0.9
1.6
0.9
2.3
0.8
1.1
1.39

YLR142W
4.4
2.7
1.1
6.1
1.3
3.1
1.2
2.1
3.1
4.4
3.8
0.8
1.2
2.1
1.6
3.4
1.9
3.2
0.28

YML110C
1.1
0.8
1.9
1.6
0.8
2.6
2.0
1.4
2.7
2.2
1.7
1.1
1.8
1.4
1.3
2.3
1.1
1.6
2.01

YNL284C
1.1
0.7
0.3
1.4
1.8
1.0
2.8
1.6
0.9
1.9
1.3
0.7
1.0
1.5
0.8
2.4
1.0
1.5
1.26

YDR268W
0.8
1.5
0.4
1.2
2.2
1.0
2.4
1.0
1.0
2.0
1.1
0.7
1.0
1.4
1.0
1.6
1.1
1.2
0.47

YMR193W
1.4
1.2
0.5
1.9
2.2
1.7
2.7
1.7
0.8
1.1
1.6
0.6
0.9
1.5
0.8
3.7
1.1
1.7
0.93

YOR374W
1.3
4.5
7.3
3.9
0.9
1.4
1.9
0.9
2.3
5.9
2.6
1.5
1.7
1.1
2.5
2.5
1.2
2.4
1.24

YER061C
0.9
0.9
1.2
2.5
0.8
0.4
0.9
0.7
0.3
0.7
2.2
0.7
0.9
1.0
0.8
1.8
1.2
1.2
0.84

YIL136W
1.1
1.0
1.2
2.5
1.0
1.0
1.8
1.1
3.4
1.7
4.8
0.9
1.7
1.7
1.5
4.5
1.3
3.2
0.95

YLL009C
1.0
1.2
0.6
1.9
1.5
1.2
1.7
1.0
1.3
1.7
3.5
0.7
0.9
1.4
1.1
2.8
0.9
1.2
1.66

YLR163C
1.0
0.9
0.7
1.4
1.6
1.3
1.7
1.4
2.6
2.9
2.2
0.7
1.4
1.3
1.2
1.4
0.9
1.1
0.55

YBR291C
2.0
0.9
1.0
1.5
0.9
1.1
0.9
2.2
0.9
1.0
1.1
0.9
1.0
1.7
0.5
1.5
0.9
1.3
1.19

YIL094C
1.5
0.4
0.8
0.7
1.4
1.2
1.3
3.6
0.3
0.4
1.8
1.0
0.7
1.0
0.5
0.9
0.9
1.0
2.26

YAL015C
1.2
1.1
1.7
1.9
1.1
0.7
1.2
1.1
4.0
2.7
1.4
1.0
1.2
1.6
0.7
2.0
1.1
1.2
0.61

YJR095W
1.2
20.5
1.9
6.7
1.2
1.5
2.0
0.9
0.5
6.3
0.6
0.7
0.8
1.3
0.8
0.8
1.3
0.9
0.23

YKL085W
1.4
2.3
1.6
1.2
1.2
1.9
1.5
1.2
1.9
3.0
1.8
0.8
1.5
1.0
0.5
1.7
0.9
1.3
2.16

YMR177W
1.4
0.8
1.1
1.0
1.6
0.8
1.0
1.2
2.4
3.8
1.4
0.6
0.5
1.2
0.8
0.5
0.9
0.9
0.55

YPL224C
1.0
2.2
1.3
2.5
0.6
1.3
2.2
1.3
3.2
4.2
0.8
1.1
1.3
1.4
1.0
2.5
1.3
1.9
0.64

YER014W
1.0
0.9
0.9
0.6
0.8
4.0

1.2
3.5
1.1
0.9
1.1
1.5
1.2
2.3
0.8
1.0
0.9
0.43

YFR049W
1.5
1.5
1.8
1.2
1.3

1.3
2.6
1.5
1.7
1.2
1.4
1.2
0.7
0.9
1.3
1.0
0.83

YGR112W
1.0
2.9
1.1
1.3
0.9
1.1
1.3
1.3
2.6
1.3
1.3
0.7
1.1
1.1
1.2
2.8
0.9
1.2
0.31

YLL001W
0.9
0.7
1.2
1.2
0.6
1.0
0.8
1.0
3.5
2.4
0.9
0.7
1.7
1.2
0.9
1.3
0.9
1.3
0.70

YML042W
0.9
1.4
1.5
2.2
1.0
0.9
0.8
1.6
3.8
2.4
2.5
1.0
1.2
1.4
1.7
4.8
1.0
0.9
0.29

YNL213C
1.7
11.6
0.9
1.5
1.3
1.2
1.4
1.8
3.0
1.5
1.5
0.8
0.9
1.8
1.0
1.7
0.9
1.2
0.70

YOR386W
1.0
0.8
1.3
1.5
1.2
3.3
1.8
1.0
4.1
3.0
1.4
1.2
2.4
0.9
1.3
1.2
2.1
1.7
0.46

YBR037C
0.8
0.8
1.3
2.4
0.7
1.2
1.2
1.0
3.0
1.9
1.5
0.7
1.2
1.2
1.0
2.7
1.6
1.3
0.60

YCR024C
1.1
1.0
1.5
0.8
0.8
2.9
1.0
1.2
2.5
1.7
1.4
0.8
0.9
1.3
1.0
1.2
0.9
1.0
0.32

YDR194C
0.7
0.9
0.5
1.0
1.0
1.0
1.3
1.4
2.8
2.2
1.2
0.6
1.2
0.8
1.1
0.8
0.6
0.8
2.19

YER017C
0.8
1.1
1.4
1.3
1.0
0.5
1.1
0.5
2.7
1.8
0.9
1.0
1.5
1.1
2.1
1.0
0.9
1.0
0.43

YGL125W
1.0
3.2
4.3
0.7
0.9

1.7
0.8
2.1
2.1
1.6
1.0
1.4
1.0
1.9
1.2
1.2
1.1
0.27

YGR029W
1.1
1.4
1.0
1.0
0.8
0.6
1.6
1.7
2.7
1.1
1.2
0.6
1.0
2.0
0.4
1.1
1.1
1.3
0.71

YHL038C
1.0
1.2
1.4
0.8
1.3
0.8
1.2
1.1
4.0
1.7
0.8
1.6
1.3
0.6
0.8
0.5
0.9
0.6
1.95

YKL192C
1.1
1.0
3.7
1.1
1.1
1.8
1.1
0.9
3.5
1.6
1.1
1.2
1.7
1.5
1.2
2.1
1.0
0.8
1.57

YKR052C
0.9
1.1
2.6
2.6
1.0
0.5
1.9
1.1
1.9
3.6
1.3
0.9
1.2
1.1
0.5
2.5
0.8
1.5
1.15

YML078W
1.2
1.9
2.5
1.5
0.7
1.4
1.3
1.4
2.6
2.2
2.4
1.2
1.7
1.7
1.0
1.8
1.3
1.6
1.98

YMR056C
1.1
1.3
1.7
1.0
1.1
0.9
1.4
1.2
1.8
1.1
1.6
0.9
0.9
1.1
0.7
2.4
1.0
1.1
0.72

YNL005C
1.1
1.0
0.6
1.2
1.2
1.7
1.3
1.5
2.0
2.0
1.2
0.9
1.5
1.3
1.0
1.6
0.9
1.5
1.52

YPR047W
1.0
1.0
0.9
1.5
0.9
1.0
1.8
1.2
2.1
1.9
1.1
0.9
1.3
1.0
0.8
2.8
1.0
1.5
0.39

YPR134W
1.1
1.1
0.8
1.7
1.5
0.6
1.5
1.4
1.8
2.3
1.3
0.9
1.1
1.5
0.7
2.4
1.0
1.2
0.65

YGL191W
1.7
1.6
1.4
1.8
0.9
1.6
1.0
1.6
1.1
1.3
1.6
0.9
1.1
1.6
0.7
1.8
1.2
1.7
2.35

YLR038C
2.3
1.1
0.6
2.1
1.8
1.2
1.0
1.4
0.4
0.9
1.4
0.6
0.5
1.6
0.7
2.1
1.2
2.1
1.52

YHR008C
1.3
5.4
4.8
1.8
0.6
1.0
0.7
0.9
1.7
2.4
2.1
0.7
1.2
1.6
1.7
2.2
0.9
1.0
1.04

YPR037C
1.2
2.3
1.6
1.3
0.8
0.9
1.2
1.1
1.5
1.3
0.9
0.9
1.0
1.6
4.1
1.8
1.2
1.7
0.80

YAL039C
1.1
2.2
1.7
1.0
1.1
0.8
1.0
1.2
1.6
2.2
1.1
1.4
1.6
1.2
3.3
2.2
1.4
1.1
0.39

YDL181W
1.3
1.8
1.9
1.8
1.7
1.2
1.1
0.6
0.7
0.8
0.8
0.9
0.9
1.1
0.4
1.1
1.5
1.4
0.85

YPL215W
1.1
1.9
1.0
1.5
0.8
0.7
0.7
1.1
1.7
1.2
1.1
0.7
0.7
1.2
0.6
1.4
1.0
1.1
1.10

YPL262W
1.0
1.7
3.8
1.2
0.6
1.6
1.3
1.0
1.4
5.8
1.4
1.1
1.5
1.2
0.6
1.4
1.1
1.2
0.79

YNL256W
0.7
1.6
0.6
0.6
1.0
0.5
0.6
0.9
0.8
0.6
0.6
0.6
1.3
0.7
0.9
0.4
0.6
0.6
1.09

YBL030C
1.0
0.9
4.5
0.9
0.7
1.1
0.9
0.8
0.4
0.9
1.1
0.9
0.5
0.8
1.8
1.0
1.0
1.1
3.12

YBR221C
0.8
0.7
3.2
1.5
1.3
1.7
1.5
0.8
1.0
1.3
1.2
1.3
1.7
0.8
1.1
1.5
0.9
1.0
3.62

YKL141W
1.6
1.1
4.7
1.7
1.5
1.2
0.5
0.8
0.8
0.5
1.2
0.8
0.8
1.4
0.6
2.8
0.9
1.8
2.84

YKR066C
0.9
1.4
5.5
0.7
1.0
0.9
0.5
0.7
0.7
2.4
1.3
0.9
0.6
1.5
0.6
1.3
0.9
1.1
1.25

YMR083W
1.4
1.7
2.6
1.1
1.5
1.8
1.7
1.1
0.4
1.1
1.6
0.7
0.9
0.8
1.3
1.3
0.9
1.1
2.52

YMR203W
0.8
0.7
3.0
1.4
0.6
1.1
0.8
0.7
0.7
1.2
2.3
0.7
1.1
0.7
1.2
0.9
0.8
0.7
1.62

YBL099W
0.8
0.9
3.1
1.4
1.0
0.9
0.9
0.8
0.9
0.7
2.1
1.0
0.9
0.6
1.0
0.9
0.7
1.2
3.49

YDR178W
2.0
2.0
3.4
2.2
0.9
2.1
0.6
0.9
0.9
0.8
2.0
1.3
1.5
1.5
0.7
3.0
1.2
2.3
2.27

YDR298C
1.3
1.2
2.6
1.3
1.3
1.2
1.0
1.2
1.0
1.6
1.2
1.1
1.2
1.5
0.8
2.0
1.1
1.6
2.69

YEL024W
1.3
0.9
3.8
1.1
1.3
1.1
0.7
1.0
0.7
0.6
0.9
0.8
0.6
1.1
0.6
2.1
1.1
1.5
1.59

YGR082W
1.0
0.9
2.2
1.0
0.9
1.1
0.9
0.8
0.6
0.9
1.3
0.8
0.5
0.9
1.2
1.3
0.9
0.8
1.47

YJL133W
1.0
1.0
2.0
0.9
0.9
0.5
0.5
0.9
0.6
1.4
1.2
0.8
0.8
0.7
0.9
0.6
0.8
0.7
0.91

YJR077C
1.1
1.1
2.0
1.6
0.9
0.9
0.7
0.8
0.4
0.7
1.6
1.0
0.9
0.7
1.5
0.7
1.0
0.8
1.79

YJR121W
0.9
1.1
3.3
1.0
0.8
1.5
1.0
0.7
0.8
1.3
0.9
0.8
1.0
0.7
0.9
1.2
1.1
1.4
3.99

YKL148C
0.9
0.8
3.7
0.7
0.8
0.5
0.6
0.8
1.7
1.7
1.5
0.8
0.8
0.8
0.6
1.1
0.8
1.0
0.54

YLL041C
1.1
0.5
4.6
1.0
1.6
1.2
0.3
0.8
0.7
0.8
1.3
0.8
1.0
1.2
0.4
3.1
1.1
1.7
1.75

YLR304C
0.7
0.6
5.0
0.7
0.6
1.9
0.6
0.6
0.1
2.2
1.6
1.0
0.5
0.7
1.6
1.8
0.5
0.7
2.39

YOR142W
1.0
1.2
3.4
1.0
1.4
1.6
1.0
0.8
1.1
1.5
1.5
0.8
1.4
0.8
1.1
0.8
0.9
1.0
1.31

YOR176W
0.7
2.6
2.7
0.9
1.0
0.9
0.5
1.0
1.0
0.5
1.4
1.3
1.5
0.8
0.8
1.4
1.2
2.1
1.23

YPL135W
0.9
1.2
2.5
1.2
1.6
1.3
1.2
1.0
0.5
2.8
1.3
1.1
1.2
1.1
1.5
1.2
1.5
1.7
1.50

YDR529C
1.8
1.0
0.9
3.2
1.2
0.8
0.5
1.3
0.5
0.6
0.8
0.6
0.7
1.5
0.5
1.8
1.0
2.3
3.11

YGL018C
1.1
1.0
1.8
3.0
1.1
0.4
1.1
0.8
0.5
1.4
1.1
1.0
1.3
1.2
1.1
1.5
0.8
1.0
0.36

YBR003W
0.9
0.8
1.0
1.9
0.7
1.2
1.1
0.9
1.0
1.3
1.3
0.8
1.2
0.8
0.7
2.0
1.1
1.3
1.06

YBR044C
0.8
1.4
0.7
1.9
1.4
1.0
1.5
1.1
0.8
1.2
1.1
0.8
1.2
0.9
0.9
1.4
0.9
1.3
0.57

YBR091C
1.1
1.0
0.6
3.0
1.1
0.7
1.0
1.5
0.7
1.6
0.7
0.8
1.2
1.7
0.9
0.9
1.0
1.0
0.87

YBR185C
1.2
1.0
1.3
2.0
0.8
1.2
1.2
1.1
0.9
1.6
1.2
0.7
1.0
1.7
1.0
1.7
0.8
1.3
0.89

YBR282W
1.0
1.0
0.5
2.3
1.0
1.4
1.2
1.4
1.0
0.9
0.9
0.8
1.3
1.4
1.1
1.5
0.9
1.2
1.36

YDR347W
1.1
0.8
0.9
3.5
0.8
1.2
1.2
1.2
0.8
1.6
0.8
0.8
1.3
1.5
1.0
1.7
0.9
1.2
1.33

YEL039C
1.1
0.7
1.3
5.1
0.9
1.5
0.6
1.1
1.2
1.2
1.7
0.6
0.5
1.4
0.4
3.5
0.7
1.1
1.59

YGR076C
1.3
1.6
0.6
2.3
0.9
1.2
1.7
1.9
1.2
1.8
1.7
1.0
1.4
2.3
0.5
2.3
0.9
1.5
0.97

YGR174C
1.1
1.6
0.6
2.4
1.0
1.4
1.0
1.6
1.8
0.7
1.3
0.9
1.5
1.6
0.7
3.2
1.3
2.3
1.05

YKL003C
1.1
0.7
0.8
1.8
1.0
1.0
1.4
1.2
1.5
2.2
1.7
0.7
1.3
2.0
1.0
2.3
1.0
1.2
0.90

YKL016C
1.5
1.3
0.7
1.7
1.5
0.8
1.5
1.6
1.3
1.8
1.3
1.0
1.3
1.6
0.7
1.8
1.0
1.7
2.08

YKL170W
1.0
0.8
0.5
1.9
1.3
1.5
1.5
1.2
0.9
1.1
0.7
0.8
0.9
1.3
0.8
2.1
1.1
1.4
1.27

YKL194C
0.9
0.7
0.8
1.6
1.8
1.4
2.1
1.1
1.3
1.4
1.6
0.6
1.1
1.4
0.8
1.2
1.1
1.1
0.52

YLR395C
1.8
1.3
2.2
1.9
0.7
0.4

1.0
1.0
0.9
1.5
0.6
0.5
1.7
0.4
1.2
1.2
2.3
1.76

YML120C
1.1
1.2
1.9
1.9
0.6
0.6
0.8
0.9
1.3
1.5
1.3
0.9
1.2
0.8
0.5
1.5
1.0
1.6
0.74

YOR100C
1.3
1.4
1.6
1.7
1.0
1.2
1.6
1.0
2.0
2.6
1.4
0.8
1.0
1.4
4.3
2.8
0.9
0.8
0.32

YOR150W
1.7
1.2
1.0
1.9
0.8
0.9
1.2
1.1
0.8
1.8
1.0
0.8
1.0
1.6
0.8
1.6
0.9
1.3
1.11

YOR187W
1.0
0.5
1.9
2.0
0.6
1.7
1.5
0.7
0.6
0.8
1.4
0.8
0.7
0.6
1.3
1.6
0.8
1.3
3.12

YJL166W
2.1
1.5
1.6
1.3
1.6
0.7
0.8
1.4
1.3
1.2
1.4
0.7
0.8
1.9
0.5
2.3
1.7
4.0
2.31

YMR035W
1.2
1.7
1.5
1.7
0.8
1.5
2.3
1.4
1.7
1.6
1.5
0.5
1.4
1.3
1.1
1.5
2.2
2.4
0.96

YBL038W
1.0
0.9
0.5
1.8
0.9
0.7
8.0
1.6
1.4
1.5
0.7
0.7
1.0
2.3
0.7
1.8
1.2
1.9
1.56

YDR377W
1.3
1.1
1.3
1.4
1.9
1.3
1.1
1.3
1.0
0.9
1.4
0.9
0.7
1.4
0.6
1.8
1.2
2.5
3.00

YGL187C
1.5
0.8
1.6
1.8
1.3
1.1
0.6
0.7
0.6
0.6
0.7
0.8
0.7
0.9
0.3
1.4
0.9
2.4
2.73

YCR046C
1.0
1.2
1.2
1.6
1.0
0.8
1.2
0.9
1.9
1.4
1.5
1.1
1.5
1.3
1.4
2.8
1.3
1.0
0.63

YML129C
1.1
0.9
0.9
1.2
1.7
1.7
1.8
1.2
1.4
2.2
1.2
0.8
1.0
1.4
1.1
2.9
1.3
1.3
1.04

YOL096C
1.1
1.0
1.2
1.6
1.2
1.3
1.7
1.0
1.3
1.4
1.2
1.2
1.4
1.4
1.0
2.3
1.2
1.2
0.64

YBR122C
0.9
0.9
0.3
1.1
1.5
1.1
2.0
1.3
1.1
1.4
1.2
0.7
0.8
1.2
0.7
1.9
0.9
1.5
1.53

YBR251W
1.0
0.9
1.0
1.2
1.3
2.0
1.4
1.3
0.5
1.1
1.5
1.1
1.0
1.6
0.8
3.0
0.9
1.4
1.13

YCR083W
1.1
2.8
1.5
1.8
1.6
2.4
1.8
1.5
1.8
1.8
1.8
1.1
1.8
2.4
1.0
3.1
1.3
1.3
0.98

YDL067C
1.8
1.0
1.6
1.3
2.0
0.9
0.8
1.1
0.9
0.9
1.4
1.0
0.6
1.4
0.7
1.8
1.2
1.7
1.85

YDR079W
1.3
1.1
0.8
1.1
1.2
1.7
1.3
2.6
0.9
0.8
1.3
1.1
1.3
1.5
0.6
2.6
1.1
1.3
1.06

YGR062C
0.9
1.0
0.7
1.4
0.7
0.9
1.3
0.8
1.0
1.4
1.6
1.0
1.5
1.2
0.5
1.8
0.9
1.1
0.54

YJL096W
1.0
1.0
0.8
1.3
1.9
1.0
1.7
1.3
1.0
1.4
1.2
1.0
0.7
2.1
1.0
2.2
1.1
1.2
1.21

YJL180C
0.9
1.6
1.1
1.3
1.5
1.3
1.6
1.0
1.4
1.4
1.4
0.8
1.2
1.4
0.6
2.0
0.9
1.4
1.08

YLR295C
1.4
1.1
1.1
1.7
2.2
1.1
1.1
1.2
1.4
1.2
1.3
0.5
0.8
1.2
0.5
2.4
0.9
1.5
1.07

YMR023C
1.4
1.3
0.5
1.9
1.7
1.1
1.9
1.4
1.5
2.6
0.8
0.7
1.1
1.6
0.7
2.1
1.1
1.4
0.48

YMR267W
0.8
1.8
0.7
0.9
1.0
1.4
1.2
1.5
0.4
0.8
1.0
0.8
0.7
1.0
0.9
2.6
0.9
1.3
0.94

YNL073W
0.8
1.4
0.9
1.7
0.6
0.5
1.1
1.0
0.9
1.8
1.1
0.7
1.2
0.7
0.7
1.8
0.8
1.0
0.52

YOR316C
0.7
2.5
1.5
1.5
1.0
0.9
1.4
0.8
1.6
2.0
2.4
1.1
1.6
1.0
1.5
2.2
0.8
1.0
0.93

YPL040C
1.1
1.0
0.8
1.7
0.8
1.1
0.8
1.1
0.2
1.2
0.9
0.9
1.0
1.1
1.1
2.7
0.8
1.1
0.33

YPL134C
1.5
1.0
1.6
1.6
1.4
1.2
1.2
1.3
0.6
0.8
1.7
0.8
1.0
1.4
1.1
3.3
1.3
1.3
0.70

TABLE 3

3 DNA repair protein genes

The level of expressed mRNA in the presenoe of chemical substance/The level of expressed mRNA in the absence of chemical substance

yeast genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity

YFL014W
3.4
5.1
5.7
11.0
1.0
9.3
5.5
3.4
13.1
5.8
5.0
4.3
15.2
7.3
6.3
14.2
1.5
8.8
2.14

YGL163C
0.9
0.8
0.6
4.3
1.5
0.9
1.0
1.4
5.8
2.3
0.4
0.9
3.1
1.6
1.8
1.0
0.9
0.8
0.26

YKL145W
0.8
1.4
1.2
1.0
1.4
2.1
1.6
1.5
3.5
2.7
1.8
1.3
2.7
1.0
1.3
1.2
1.1
1.5
2.29

YIL153W
0.8
1.4
1.3
2.9
1.0
0.9
1.6
0.5
4.3
1.1
1.0
1.0
1.2
1.0
2.8
1.3
0.9
0.7
0.32

YIR002C
0.8
1.1
0.5
0.6
1.2
2.2
1.3
1.2
1.7
1.4
0.8
1.3
1.2
1.1
1.1
1.4
1.1
1.2
0.58

YAL015C
1.2
1.1
1.7
1.9
1.1
0.7
1.2
1.1
4.0
2.7
1.4
1.0
1.2
1.6
0.7
2.0
1.1
1.2
0.61

YBR073W
0.7
1.0
0.9
0.7
1.2
0.7
0.6
1.1
2.5
1.8
0.5
0.9
1.4
1.0
1.3
0.8
0.7
0.8
0.63

YDL200C
1.4
2.0
1.2
1.8
1.1
0.6
1.7
1.5
2.4
1.8
1.2
1.1
1.1
1.8
0.7
1.8
0.9
1.6
0.79

YGL058W
1.1
1.1
0.6
0.7
1.0
1.0
0.0
1.3
3.7
1.8
0.8
1.3
1.0
1.3
1.3
0.6
1.1
0.7
1.07

YIL143C
0.9
0.8
1.1
0.9
0.8
1.4
0.8
0.9
7.1
3.5
1.5
0.9
1.7
1.0
1.3
1.1
0.9
0.9
0.56

YML032C
0.8
0.9
1.1
0.7
1.0
0.9
0.8
0.9
3.0
1.1
1.0
0.9
1.8
1.0
1.7
1.2
1.0
1.0
0.66

YNL250W
0.9
2.2
0.8
1.2
0.8
0.8
1.2
1.3
4.2
2.3
1.0
1.4
1.3
1.6
1.3
1.4
1.0
1.0
0.31

YOR386W
1.0
0.8
1.3
1.5
1.2
3.3
1.8
1.0
4.1
3.0
1.4
1.2
2.4
0.9
1.3
1.2
2.1
1.7
0.46

YBL019W
0.9
9.1
0.7
1.2
1.0
1.0
1.2
1.2
2.6
1.4
1.0
0.8
0.9
1.1
0.6
1.9
0.8
1.1
0.38

YDR369C
1.1
1.1
2.4
1.1
1.0
0.6
0.4
1.0
2.4
1.8
1.1
0.9
0.1
0.7
1.2
0.6
0.8
0.7
1.88

YEL037C
0.9
2.0
0.9
1.0
0.5
0.6
0.8
0.8
2.6
1.2
1.0
1.1
2.0
1.0
1.6
0.5
1.0
0.8
0.82

YER162C
1.0
1.2
1.0
1.1
0.9
0.7
0.5
0.9
2.8
1.6
0.5
0.4
0.8
0.8
1.0
1.0
1.2
0.9
0.45

YGR2S8C
0.7
0.9
0.7
0.7
1.5
2.2
1.5
0.8
2.5
1.5
0.3
0.9
1.9
1.2
1.1
1.2
1.0
0.9
0.37

YJR052W
1.1
1.0
1.1
1.0
1.0
1.4
1.2
1.7
4.5
2.3
1.1
1.1
1.8
1.4
1.4
1.4
1.0
1.3
0.36

YOR005C
1.2
1.8
1.0
0.8
1.3
1.3
1.4
1.3
2.4
1.5
1.2
0.9
2.1
1.2
0.8
1.4
1.1
1.0
0.29

YPL022W
0.7
0.8
0.7
1.2
0.8
5.2
0.8
1.0
2.1
1.6
0.8
0.7
1.4
0.9
0.9
1.0
0.9
0.9
0.72

YPL164C
1.1
0.7
1.1
1.0
1.2
1.7
0.9
1.0
2.1
2.0
1.1
0.9
1.0
0.9
1.3
1.4
1.0
1.0
0.25

YPL194W
0.9
1.4
0.4
1.1
1.3
1.1
1.5
1.3
9.6
3.1
0.9
0.9
1.4
1.1
1.4
0.9
1.0
0.8
0.22

YPR025C
1.1
0.8
0.6
0.6
1.6
0.9
1.4
1.3
1.9
1.7
0.9
0.7
1.1
1.3
1.1
1.3
1.1
1.5
0.87

YGR180C
3.1
1.1
1.9
1.0
2.0
0.6
0.5
1.0
1.4
1.5
1.0
0.9
0.9
0.9
1.3
1.2
1.0
1.9
3.90

YEL019C
1.1
1.6
0.3
0.7
0.9
1.5
1.2
0.9
0.7
0.7
1.2
1.0
1.0
1.7
1.5
0.3
0.8
0.9
0.27

YLR288C
1.2
0.8
1.6
1.8
1.7
1.2
1.3
1.5
0.8
1.3
1.4
0.6
0.7
1.2
0.9
1.5
1.2
1.3
0.31

YMR284W
1.1
1.0
0.5
2.0
0.8
0.8
0.8
1.1
1.6
1.8
1.1
0.6
1.0
1.2
0.7
1.3
1.1
1.3
0.54

YMR035W
1.2
1.7
1.5
1.7
0.8
1.5
2.3
1.4
1.7
1.6
1.5
0.5
1.4
1.3
1.1
1.5
2.2
2.4
0.96

YOL043C
1.1
0.9
0.8
1.7
1.2
0.8
1.0
0.9
1.0
1.8
1.2
0.8
0.9
1.5
0.6
2.5
1.0
1.0
0.38

YGR231C
1.0
1.2
0.7
1.0
1.3
1.9
2.1
1.1
3.2
2.3
1.6
1.3
3.9
2.2
1.3
2.5
1.0
1.5
1.74

YHR164C
0.9
1.3
0.9
0.7
0.9
1.4
0.8
1.1
1.3
3.1
0.6
1.2
2.0
1.3
2.2
1.1
0.8
1.0
0.44

YJR046W
1.0
1.2
1.2
1.5
0.8
2.0
0.9
0.9
6.0
2.4
0.6
0.9
3.0
1.0
1.1
0.8
0.7
0.7
0.45

YLR103C
0.8
1.5
1.1
0.4
1.0
1.1
1.3
1.4
0.8
0.5
0.9
1.6
3.0
1.0
0.8
1.5
1.1
1.4
1.32

YMR072W
1.1
1.0
1.4
1.0
1.7
1.6
1.4
1.0
3.0
1.2
1.9
0.8
2.1
1.2
0.8
1.7
0.9
1.9
2.06

YDR054C
1.3
1.0
0.7
1.4
0.7
1.9
1.1
1.5
2.9
3.2
1.9
1.0
2.5
1.1
1.6
1.4
0.8
1.4
1.18

YAR007C
0.7
1.9
0.8
0.5
1.5
1.6
0.8
1.1
4.1
1.7
0.9
0.9
1.7
1.4
1.2
0.9
0.8
1.0
1.03

YGL058W
1.1
1.1
0.6
0.7
1.0
1.5
0.0
1.3
3.7
1.8
0.8
1.3
1.0
1.3
1.3
0.6
1.1
0.7
1.07

YIL036W
0.9
1.3
1.3
1.8
0.9
1.8
1.4
1.1
3.6
2.7
1.2
1.2
1.9
1.1
0.8
1.3
1.1
1.3
0.66

YNL213C
1.7
11.6
0.9
1.5
1.3
1.7
1.4
1.8
3.0
1.5
1.5
0.8
0.9
1.8
1.0
1.7
0.9
1.2
0.70

YNL312W
0.9
1.0
1.6
0.7
1.4
1.7
0.5
1.2
3.7
2.5
1.4
0.9
0.7
1.1
0.8
0.8
1.2
1.1
2.05

YNL261W
1.0
1.3
0.6
1.3
0.7
1.3
1.0
1.1
2.3
1.5
0.8
0.8
0.8
1.4
0.7
1.1
0.8
1.0
0.91

YGR180C
3.1
1.1
1.9
1.0
2.0
1.0
0.5
1.0
1.4
1.5
1.0
0.9
0.9
0.9
1.3
1.2
1.0
1.9
3.90

YJL026W
2.5
2.4
2.9
1.0
1.7
1.0
0.5
1.2
1.0
1.1
1.3
1.0
1.2
1.0
1.1
1.6
1.4
2.1
3.74

YDL017W
0.8
2.3
1.2
1.3
1.2
1.1
1.1
1.2
0.8
1.8
0.8
0.8
0.9
1.3
1.3
1.0
0.8
1.0
0.38

YML058W
1.9
1.2
5.8
1.9
0.6
1.3
0.6
0.7
1.1
1.2
3.3
0.9
1.4
1.1
2.5
1.3
1.3
1.5
2.14

YLR233C
1.1
0.9
2.0
2.0
1.2
0.8
0.8
1.1
0.6
0.5
0.8
0.9
1.0
1.1
1.1
1.1
1.0
1.2
0.43

YMR284W
1.1
1.0
0.5
2.0
0.8
1.2
0.8
1.1
1.6
1.8
1.1
0.6
1.0
1.2
0.7
1.3
1.1
1.3
0.54

YGL163C
0.9
0.8
0.6
4.3
1.5
0.9
1.0
1.4
5.8
2.3
0.4
0.9
3.1
1.6
1.8
1.0
0.9
0.8
0.26

YGL127C
1.0
1.9
1.3
1.7
1.3
0.6
1.0
0.9
1.2
1.5
1.0
1.4
1.7
1.0
1.5
1.3
1.0
1.2
0.54

YMR072W
1.1
1.0
1.4
1.0
1.7
2.4
1.4
1.0
3.0
1.2
1.9
0.8
2.1
1.2
0.8
1.7
0.9
1.9
2.06

YGL249W
1.4
0.8
0.5
0.8
1.1
2.5
1.2
0.9
0.3
2.4
0.6
0.8
0.8
1.9
0.7
1.4
1.0
1.0
0.20

YBR272C
0.8
1.8
1.3
1.0
1.1

1.9
1.1
1.7
2.7
1.1
0.5
1.3
1.0
0.5
1.7
1.1
1.2
0.52

YDL059C
2.6
5.1
1.4
1.7
1.2
1.2
1.1
1.2
10.5
7.8
2.0
1.3
1.7
4.7
0.7
1.5
0.8
0.9
0.63

YAR007C
0.7
1.9
0.8
0.5
1.5
0.6
0.8
1.1
4.1
1.7
0.9
0.9
1.7
1.4
1.2
0.9
0.8
1.0
1.03

YBR073W
0.7
1.0
0.9
0.7
1.2
0.7
0.6
1.1
2.5
1.8
0.5
0.9
1.4
1.0
1.3
0.8
0.7
0.8
0.63

YML032C
0.8
0.9
1.1
0.7
1.0
0.9
0.8
0.9
3.0
1.1
1.0
0.9
1.8
1.0
1.7
1.2
1.0
1.0
0.66

YNL250W
0.9
2.2
0.8
1.2
0.8
0.8
1.2
1.3
4.2
2.3
1.0
1.4
1.3
1.6
1.3
1.4
1.0
1.0
0.31

YCR014C
0.8
1.0
0.8
0.6
1.2
1.1
1.1
1.0
2.4
1.0
0.8
0.7
1.2
1.0
0.7
1.5
1.0
0.9
0.34

YDR369C
1.1
1.1
2.4
1.1
1.0
0.6
0.4
1.0
2.4
1.8
1.1
0.9
0.1
0.7
1.2
0.6
0.8
0.7
1.88

YIL072W
0.8
3.1
1.1
2.6
1.5
1.2
1.7
1.4
2.9
2.1
1.8
1.1
1.4
2.0
1.4
1.4
1.0
1.1
0.23

YOR005C
1.2
1.8
1.0
0.8
1.3
1.3
1.4
1.3
2.4
1.5
1.2
0.9
2.1
1.2
0.8
1.4
1.1
1.0
0.29

YPL164C
1.1
0.7
1.1
1.0
1.2
1.7
0.9
1.0
2.1
2.0
1.1
0.9
1.0
0.9
1.3
1.4
1.0
1.0
0.25

YPL194W
0.9
1.4
0.4
1.1
1.3
1.1
1.5
1.3
9.6
3.1
0.9
0.9
1.4
1.1
1.4
0.9
1.0
0.8
0.22

YGR180C
3.1
1.1
1.9
1.0
2.0
0.6
0.5
1.0
1.4
1.5
1.0
0.9
0.9
0.9
1.3
1.2
1.0
1.9
3.90

YEL019C
1.1
1.6
0.3
0.7
0.9
1.5
1.2
0.9
0.7
0.7
1.2
1.0
1.0
1.7
1.5
0.3
0.8
0.9
0.27

YML058W
1.9
1.2
5.8
1.9
0.6
0.6
0.6
0.7
1.1
1.2
3.3
0.9
1.4
1.1
2.5
1.3
1.3
1.5
2.14

YLR288C
1.2
0.8
1.6
1.8
1.7
1.2
1.3
1.5
0.8
1.3
1.4
0.6
0.7
1.2
0.9
1.5
1.2
1.3
0.31

YMR284W
1.1
1.0
0.5
2.0
0.8
0.8
0.8
1.1
1.6
1.8
1.1
0.6
1.0
1.2
0.7
1.3
1.1
1.3
0.54

YMR096W
1.7
1.7
1.1
0.8
1.0
2.2
1.9
2.0
3.3
3.7
1.5
1.4
8.4
4.7
28.9
2.2
2.2
1.0
0.62

YGL091C
2.0
1.8
1.0
1.7
0.8
1.6
1.3
1.8
10.8
6.0
2.1
1.2
2.5
3.1
0.7
1.0
1.4
1.8
0.96

TABLE 4

Energy system protein genes

yeast
The level of expressed mRNA in the presence of chemical substance

genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)

YCR107W
12.1
2.6
1.8
1.6
0.7
1.5
1.5
15.6
196.6
34.0

YDL243C
14.5
2.7
2.4
1.0
1.1
2.2
1.6
11.8
64.2
29.6

YFL056C
19.0
2.3
2.3
1.5
0.9
0.6
1.4
18.5
162.3
31.3

YFL057C
20.9
5.9
1.5
1.8
0.9
1.2
1.8
18.0
51.8
46.1

YJR155W
7.6
3.7
1.4
2.5
0.7
1.4
1.7
10.6
38.2
18.8

YNL331C
8.6
3.6
1.3
1.0
1.6
1.8
1.9
13.1
42.6
36.3

YOL165C
10.1
4.5
1.8
0.9
0.9
1.7
1.4
17.8
46.9
23.3

YPL171C
15.2
4.1
3.5
2.2
1.1
1.3
1.7
20.5
60.0
50.6

YDL021W
5.1
1.7
2.4
3.7
1.7
6.5
5.9
2.7
2.5
7.4

YGR043C
2.6
3.7
3.2
7.9
0.9
16.3
6.5
2.6
10.9
8.4

YHR179W
3.3
2.3
2.6
0.7
1.2
3.7
1.9
3.3
3.6
5.8

YJR048W
1.3
0.9
2.2
1.4
0.8
0.5
0.3
0.9
0.5
1.5

YKR097W
1.6
2.4
1.3
3.3
1.1
1.7
3.7
2.5
1.9
3.3

YML087C
1.8
1.6
0.8
2.5
0.9
0.9
1.1
1.3
1.9
4.9

YPL088W
3.3
1.3
0.6
2.5
1.5
7.1
3.7
1.9
0.6
2.8

YDL174C
0.9
1.8
0.9
1.3
0.5
1.7
3.6
0.8
0.5
1.7

YCR012W
1.2
1.5
5.1
1.2
1.1
2.5
1.4
0.8
1.4
1.5

YFR053C
1.8
1.4
3.0
2.2
0.9
3.2
2.1
2.8
0.6
1.1

YGL062W
0.6
1.3
1.1
0.6
0.9
1.0
1.3
0.8
1.6
2.5

YGR192C
1.4
1.0
3.8
1.0
1.1
1.7
1.7
1.1
0.9
1.3

YGR244C
1.0
1.2
1.6
1.6
0.8
2.6
3.9
1.8
1.4
1.1

YGR254W
1.2
1.3
3.8
1.3
1.2
1.9
1.5
1.4
0.8
1.2

YIL160C
0.8
2.4
2.3
3.5
1.0
1.6
1.1
1.2
3.2
3.8

YJL052W
1.6
0.9
4.0
1.8
0.7
2.4
2.1
1.5
1.6
2.0

YJR009C
1.1
1.7
5.6
1.0
1.2
1.6
1.6
1.1
1.1
1.3

YLR345W
1.4
1.4
1.4
1.2
1.2
1.6
1.2
1.4
4.5
4.0

YMR118C
1.3
2.9
1.4
1.6
1.2
2.0
1.0
1.0
9.3
1.4

YNL071W
0.9
0.9
1.7
1.5
0.6
1.3
1.4
0.9
1.1
1.2

YNL241C
1.3
2.5
4.3
1.0
0.8
0.9
3.2
0.9
3.4
7.4

YPL240C
0.7
1.4
2.4
0.9
1.3
1.2
1.4
1.2
3.5
2.6

YAL060W
1.1
1.8
3.2
2.7
1.2
4.2
3.3
0.9
0.6
2.5

YCL040W
0.9
5.6
10.1
2.0
0.5
3.5
2.9
0.7
0.9
3.0

YDR001C
1.0
2.2
2.6
1.0
1.1
2.2
1.5
0.9
2.2
3.0

YDR231C
1.1
1.6
1.0
1.5
1.1
2.2
1.7
1.3
1.5
1.4

YER178W
0.8
0.9
3.6
1.0
0.7
2.5
1.6
0.8
1.7
1.3

YGR008C
2.4
3.0
1.7
3.2
0.9
2.9
3.7
1.9
3.1
2.4

YGR256W
1.2
1.5
2.3
0.8
0.9
6.2
1.4
2.2
3.4
2.5

YHL008C
0.9
0.5
1.0
1.6
0.8
0.8
0.7
0.9
1.6
1.7

YHR174W
1.1
1.4
3.3
1.2
1.3
1.5
1.6
1.2
1.0
1.5

YIL045W
1.7
1.4
1.9
2.2
1.3
1.7
1.6
1.1
2.1
3.2

YKL035W
1.0
0.9
4.8
1.2
0.8
1.2
0.6
1.0
0.8
1.2

YKL152C
1.4
1.3
1.9
0.9
1.3
1.6
1.5
1.0
0.9
1.5

YML054C
1.5
1.8
1.3
3.4
1.3
1.8
1.2
1.5
4.1
1.8

YML100W
0.8
2.7
10.6
1.4
0.9
2.8
2.2
0.7
1.7
1.4

YML125C
0.8
0.9
0.7
0.7
0.9
1.3
1.0
1.3
2.6
1.6

YMR089C
1.0
1.1
0.9
0.9
0.8
1.2
1.2
1.3
5.6
2.5

YMR105C
2.0
3.0
5.0
4.2
0.9
2.8
2.8
1.1
0.6
2.9

YNL237W
1.3
1.3
1.5
1.0
1.5
4.6
4.9
1.1
0.9
2.1

YOL126C
1.1
0.8
1.0
1.6
0.7
1.5
1.4
0.9
0.8
2.4

YOR347C
0.9
0.9
2.1
2.2
0.7
0.9
0.9
0.8
0.5
0.9

YPR026W
0.9
1.2
5.0
1.3
0.8

1.3
1.0
0.9
3.1

YAL038W
1.0
1.0
3.0
1.4
1.4
1.3
0.9
1.1
0.1
1.1

YDR380W
0.8
0.8
0.8
1.7
1.1
0.4
0.5
0.2
0.2
0.3

YLR273C
1.5
1.0
1.3
2.4

1.2
1.2
1.3
2.8
2.4

YGR207C
1.5
1.1
1.0
1.1
1.5
2.8
1.7
1.9
2.1
2.6

YNL037C
1.4
1.8
1.7
1.1
1.7
2.8
2.8
1.0
0.6
3.2

YOR136W
1.0
0.9
3.5
1.0
1.5
3.9
3.2
1.1
0.3
3.4

YPL271W
1.2
3.2
4.1
1.2
1.4
3.3
1.2
0.9
0.6
1.2

YAL054C
1.2
1.1
1.4
1.6
1.1
2.2
1.1
1.1
8.9
4.1

YEL011W
2.0
1.6
1.7
6.3
1.1
2.8
2.7
0.9
2.5
1.6

YFR015C
1.2
0.8
3.2
2.1
1.2
3.0
7.3
0.7
0.3
1.8

YGL253W
0.8
1.0
3.2
0.7
1.3
2.4
1.7
1.1
0.3
1.4

YIL111W
1.9
1.0
1.8
2.7

2.6
3.2
1.2
1.6
1.1

YKL150W
1.1
2.0
3.0
1.4
1.4
2.3
2.4
1.3
1.1
1.3

YPR006C
1.9
1.5
0.5
1.9
2.0
2.4
2.8
1.5
1.5
3.9

YBR145W
1.5
0.7
2.8
0.9
1.1
11.5
58.8
1.0
0.1
1.1

YBR299W
2.0
0.9
1.1
3.5
1.6
0.8
3.6
2.2
1.1
5.3

YEL020C
1.0
1.5
0.8
2.9
1.5
1.3
2.4
1.2
1.4
1.1

YGL134W
1.2
1.3
0.5
0.8
1.4
1.2
2.3
1.4
1.1
1.4

YOL157C
1.0
1.1
1.3
2.5
1.4
0.9
2.7
1.4
2.3
4.8

YBR126C
0.8
1.9
5.6
1.2
0.7
2.9
2.3
0.6
1.7

YCR005C
1.2
1.9
2.0
1.2
0.9
1.6
4.4
1.2
1.5
1.5

YIL172C
1.1
1.1
1.6
1.7

1.3
2.5
1.6
2.8
7.1

YOR221C
0.8
1.0
0.9
1.1
1.7
0.8
2.1
0.9
1.4
1.7

YBR196C
0.8
0.6
3.9
1.4
0.8
0.8
1.4
1.1
0.3
0.9

YEL047C
1.3
1.9
3.2
1.2
0.8
0.6
1.3
1.0
2.7
2.3

YMR318C
1.8
2.4
2.2
0.7
1.2
2.1
0.8
3.6
2.3
4.8

YER061C
0.9
0.9
1.2
2.5
0.8
0.4
0.9
0.7
0.3
0.7

YJL045W
1.8
2.2
1.6
5.3
0.7
0.6
0.7
0.9
9.7
1.6

YLL009C
1.0
1.2
0.6
1.9
1.5
1.2
1.7
1.0
1.3
1.7

YPR160W
1.4
3.8
3.6
3.3
0.7
4.5
1.8
0.9
0.9
1.3

YDL085W
1.2
1.9
1.2
2.0
1.2
1.2
1.4
1.0
7.8
3.4

YJL221C
1.1
1.0
1.1
1.3
0.9
6.6
2.5
1.8
2.7
4.4

YKL085W
1.5
2.3
1.6
1.2
1.2
1.9
1.5
1.2
1.9
3.0

YLR174W
1.2
1.5
1.7
2.1
0.9
0.9
1.6
1.1
2.5
8.3

YNL009W
1.1
1.9
2.0
1.4
1.4
1.1
1.2
1.1
1.4
3.3

YNL117W
0.9
4.7
1.7
0.8
0.8

1.1
1.7
12.8
4.4

YAL061W
1.7
2.4
3.3
3.8
1.0
1.0
2.0
0.8
5.5
1.4

YBR117C
0.8
1.6
1.5
1.4
0.9
2.3
1.0
0.7
5.9
1.5

YEL071W
1.1
1.6
2.6
0.4
1.3
1.9
2.0
1.2
3.6
2.8

YGR112W
1.0
2.9
1.1
1.3
0.9
1.1
1.3
1.3
2.6
1.3

YLR164W
1.0
2.4
0.3
1.0
1.2
1.2
1.1
1.2
5.3
2.0

YNR032W
1.0
1.5
1.0
2.1
1.5
1.0
1.1
1.0
6.2
2.4

YPL031C
0.9
2.0
1.4
0.8
1.5
1.8
1.6
1.0
5.7
1.4

YPR048W
1.3
2.0
0.9
1.1
0.9
0.6
0.9
1.5
4.0
2.1

YBL058W
0.9
1.5
0.5
1.1
1.6
0.9
1.5
1.2
2.6
2.1

YBR001C
0.9
1.4
1.1
1.4
0.9
1.1
0.9
1.3
2.3
2.1

YCR105W
2.2
1.2
1.2
3.0
0.9
1.0
1.0
1.4
2.0
3.9

YIR031C
0.9
1.6
0.6
0.6
1.6
1.7
1.4
1.0
2.6
1.0

YGL191W
2.3
1.6
1.4
1.8
0.9
1.6
1.0
1.6
1.1
1.3

YLR038C
2.6
1.1
0.6
2.1
1.8
1.2
1.0
1.4
0.4
0.9

YGR087C
1.0
15.0
1.7
0.6
1.0
1.1
1.0
0.8
0.2
0.9

YGL256W
0.9
5.3
1.1
1.3
0.7
0.7
0.5
1.0
0.4
1.2

YDL181W
1.4
1.8
1.9
1.8
1.7
1.2
1.1
0.6
0.7
0.8

YPL262W
1.1
1.7
3.8
1.2
0.6
1.6
1.3
1.0
1.4
5.8

YLR377C
1.1
2.6
1.8
1.2
1.0
0.7
0.9
0.7
1.8
1.6

YBR221C
0.8
0.7
3.2
1.5
1.3
1.7
1.5
0.8
1.0
1.3

YKL141W
1.6
1.1
4.7
1.7
1.5
1.2
0.5
0.8
0.8
0.5

YLR134W
0.9
0.6
2.3
0.8
1.3
2.5
1.1
0.8
0.1
0.7

YLR258W
1.7
1.0
4.2
3.5
0.9
1.8
1.8
0.9
0.8
1.3

YOR178C
1.4
1.3
4.8
2.3
1.0
2.7
0.9
0.9
0.2
1.7

YBL099W
0.8
0.9
3.1
1.4
1.0
0.9
0.9
0.8
0.9
0.7

YDR050C
1.9
1.3
2.3
1.8
0.9
1.7
1.5
1.3
0.4
1.3

YDR178W
2.0
2.0
3.4
2.2
0.9
2.1
0.6
0.9
0.9
0.8

YDR298C
1.3
1.2
2.6
1.3
1.3
1.2
1.0
1.2
1.0
1.6

YEL024W
1.5
0.9
3.8
1.1
1.3
1.1
0.7
1.0
0.7
0.6

YJL121C
1.0
0.5
1.9
0.8
1.0
1.1
0.7
1.0
0.1
0.4

YJR121W
1.2
1.1
3.3
1.0
0.8
1.5
1.0
0.7
0.8
1.3

YKL060C
1.7
0.8
2.5
1.0
1.6
1.3
1.2
1.1
0.3
0.8

YKL148C
0.9
0.8
3.7
0.7
0.8
0.5
0.6
0.8
1.7
1.7

YLL041C
1.5
0.5
4.6
1.0
1.6
1.2
0.3
0.8
0.7
0.8

YLR044C
0.8
0.6
2.2
0.9
1.7
1.5
1.3
0.7
0.0
1.2

YLR284C
0.9
1.0
3.8
1.9
1.6
0.9
0.8
1.2
0.9
0.9

YLR304C
0.7
0.6
5.0
0.7
0.6
1.9
0.6
0.6
0.1
2.2

YLR354C
1.2
2.5
2.3
1.5
1.6
1.5
1.1
1.4
0.4
0.9

YMR205C
0.5
0.7
2.3
0.8
1.2
1.2
0.9
0.7
0.3
0.8

YMR261C
0.8
1.6
3.6
0.8
0.9
0.6
1.3
0.7
1.6
1.3

YMR323W
0.8
1.1
2.9
1.1
0.7
0.4
1.1
0.8
0.5
1.3

YOL086C
1.1
0.5
2.2
1.1
1.9
1.7
1.9
0.8
0.1
1.2

YOR142W
1.3
1.2
3.4
1.0
1.4
1.6
1.0
0.8
1.1
1.5

YPL061W
0.4
1.4
5.0
1.3
1.6
1.7
0.5
0.8
1.3
0.7

YDL107W
1.3
1.3
1.0
2.2
1.0
1.3
1.8
1.8
1.2
1.8

YDR529C
1.8
1.0
0.9
3.2
1.2
0.8
0.5
1.3
0.5
0.6

YGL018C
1.5
1.0
1.8
3.0
1.1
0.4
1.1
0.8
0.5
1.4

YBR185C
1.5
1.0
1.3
2.0
0.8
1.2
1.2
1.1
0.9
1.6

YEL039C
1.1
0.7
1.3
5.1
0.9
1.5
0.6
1.1
1.2
1.2

YGR174C
1.1
1.6
0.6
2.4
1.0
1.4
1.0
1.6
1.8
0.7

YKL016C
1.5
1.3
0.7
1.7
1.5
0.8
1.5
1.6
1.3
1.8

YLR395C
1.8
1.3
2.2
1.9
0.7
0.4

1.0
1.0
0.9

YML120C
1.1
1.2
1.9
1.9
0.6
0.6
0.8
0.9
1.3
1.5

YMR073C
1.1
1.1
1.2
1.5
0.8
0.9
1.0
1.1
1.2
1.2

YOR388C
1.0
1.6
1.3
4.7
1.3
1.4
1.0
0.7
0.1
1.4

YPL275W
0.6
1.5
1.3
5.1
1.2
1.0
1.1
1.0
0.2
1.2

YPL276W
1.2
1.5
1.6
3.0
1.5
1.1
1.2
0.9
−0.2
1.8

YGL205W
1.0
0.9
0.7
0.8
1.1
1.6
0.8
1.2
0.5
0.6

YJL166W
2.1
1.5
1.6
1.3
1.6
0.7
0.8
1.4
1.3
1.2

YNL202W
0.7
1.3
1.2
1.7
0.9
2.0
0.9
1.2
1.3
1.1

YDR377W
1.3
1.1
1.3
1.4
1.9
1.3
1.1
1.3
1.0
0.9

YGL187C
1.5
0.8
1.6
1.8
1.3
1.1
0.6
0.7
0.6
0.6

YJL216C
1.1
4.7
2.2
0.9
0.8

1.5
1.9
1.5
1.3

YKR009C
1.0
1.2
1.5
0.9
1.0
1.8
1.0
0.9
2.4
2.1

YCR046C
1.0
1.2
1.2
1.6
1.0
0.8
1.2
0.9
1.9
1.4

YML129C
1.1
0.9
0.9
1.2
1.7
1.7
1.8
1.2
1.4
2.2

YPR184W
1.2
1.4
5.7
2.2
0.9
1.5
1.3
0.7
1.9
3.2

YDL067C
1.8
1.0
1.6
1.3
2.0
0.9
0.8
1.1
0.9
0.9

YDL078C
0.7
1.1
1.2
0.8
1.3
1.1
1.7
1.0
1.1
1.0

YDR079W
1.3
1.1
0.8
1.1
1.2
1.7
1.3
2.6
0.9
0.8

YGR062C
0.9
1.0
0.7
1.4
0.7
0.9
1.3
0.8
1.0
1.4

YKR058W
1.3
0.9
1.4
1.9
0.8
1.4
1.4
1.5
1.3
1.2

YLR295C
1.5
1.1
1.1
1.7
2.2
1.1
1.1
1.2
1.4
1.2

YMR267W
0.8
1.8
0.7
0.9
1.0
1.4
1.2
1.5
0.4
0.8

yeast
The level of expressed mRNA in the absence of chemical substance

genes
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity

YCR107W
23.0
0.9
4.0
8.3
4.8
3.1
1.3
1.1
0.59

YDL243C
19.6
1.1
4.1
12.0
4.2
3.0
1.8
1.5
0.76

YFL056C
68.3
1.0
4.7
7.8
5.0
3.4
1.0
1.1
0.55

YFL057C
27.7
1.0
4.1
23.4
3.1
3.9
1.6
1.3
0.71

YJR155W
15.4
1.0
5.7
9.4
2.6
5.6
1.3
1.4
0.64

YNL331C
21.8
0.9
3.1
7.5
2.3
4.0
1.7
1.3
0.58

YOL165C
17.6
0.8
3.7
9.1
3.0
1.8
1.6
1.0
0.69

YPL171C
37.0
1.4
2.4
9.3
1.4
1.2
2.4
1.5
0.47

YDL021W
4.7
2.4
5.3
3.7
0.7
7.3
1.9
3.2
0.47

YGR043C
3.6
3.3
6.9
4.1
3.0
13.7
1.6
4.8
0.66

YHR179W
2.0
2.2
2.6
5.8
2.7
1.0
1.9
1.6
2.69

YJR048W
1.0
0.8
0.4
2.5
0.6
1.5
1.2
1.2
1.19

YKR097W
0.8
1.8
17.5
2.1
2.5
2.2
1.1
1.5
0.16

YML087C
1.6
0.8
1.5
2.1
0.3
2.0
0.7
0.8
0.52

YPL088W
1.1
3.6
4.8
1.6
3.2
4.3
9.1
8.3
0.69

YDL174C
0.9
2.8
5.9
1.1
0.6
5.1
2.2
4.0
0.63

YCR012W
1.8
1.2
4.1
0.9
1.4
1.4
0.8
1.3
4.48

YFR053C
1.5
1.7
3.0
0.6
0.6
3.0
1.4
2.2
4.17

YGL062W
0.7
1.6
4.5
1.2
2.7
1.5
1.1
0.9
0.77

YGR192C
2.3
2.2
3.4
1.0
1.9
1.1
1.1
1.3
7.49

YGR244C
1.8
1.9
2.6
1.2
2.0
2.6
1.9
3.1
1.12

YGR254W
1.3
1.7
3.1
0.6
2.4
1.4
1.3
1.2
7.01

YIL160C
2.4
1.0
2.3
1.5
5.6
8.8
2.4
3.0
0.27

YJL052W
4.3
2.4
5.6
1.3
2.3
2.3
1.2
1.9
6.19

YJR009C
1.1
1.5
2.7
1.0
2.1
1.5
1.1
1.3
5.86

YLR345W
2.5
1.6
3.5
1.5
1.0
1.2
1.2
1.4
2.65

YMR118C
0.7
0.8
4.2
0.9
0.9
8.1
0.8
1.0
0.38

YNL071W
1.6
1.3
2.5
0.8
1.1
1.1
1.0
1.2
1.61

YNL241C
3.0
2.0
4.9
1.1
7.0
2.8
1.0
1.0
0.68

YPL240C
1.0
0.8
2.9
0.7
1.2
0.7
0.8
1.0
4.83

YAL060W
2.4
0.8
2.2
0.9
0.9
3.2
1.1
1.8
2.39

YCL040W
8.2
2.3
5.6
0.7
3.4
3.1
1.4
1.7
1.98

YDR001C
0.7
1.1
2.8
1.0
4.4
1.9
1.1
1.6
0.75

YDR231C
1.3
1.1
2.4
1.5
1.0
3.0
1.2
1.3
0.92

YER178W
2.5
1.3
2.4
0.9
1.8
1.0
1.1
0.9
2.18

YGR008C
2.6
2.0
3.4
1.3
1.5
2.3
1.7
4.2
3.03

YGR256W
2.7
1.5
3.9
1.1
2.7
5.3
1.1
0.8
0.94

YHL008C
1.4
0.8
1.8
1.0
1.8
0.9
0.8
0.9
0.40

YHR174W
1.4
1.5
3.6
0.6
2.0
1.1
1.0
1.2
7.34

YIL045W
1.2
1.5
2.0
1.6
0.6
2.9
1.1
1.8
0.37

YKL035W
2.1
1.0
2.0
0.6
1.0
1.5
1.0
1.9
2.54

YKL152C
1.7
1.5
2.7
1.0
1.8
2.0
1.1
1.7
3.28

YML054C
1.4
1.8
2.8
2.1
1.1
7.8
1.1
1.6
0.25

YML100W
3.2
1.2
3.8
1.2
1.8
2.2
1.0
1.5
0.88

YML125C
1.0
1.0
2.2
1.6
1.9
0.7
1.2
0.9
2.21

YMR089C
1.3
0.8
2.3
0.9
1.8
1.1
0.9
1.1
0.69

YMR105C
3.0
1.7
3.3
1.0
0.9
2.0
1.6
2.6
1.21

YNL237W
1.5
1.8
3.2
1.3
1.6
4.4
1.3
1.1
0.21

YOL126C
1.8
1.1
2.6
1.2
1.4
2.5
1.6
2.4
0.59

YOR347C
1.4
1.2
1.8
0.9
2.0
1.4
1.7
1.3
1.31

YPR026W
1.6
1.2
2.3
1.5
3.1
2.5
0.9
1.3
0.26

YAL038W
1.0
1.2
1.8
0.5
3.1
0.9
1.0
1.0
7.02

YDR380W
0.4
0.4
0.4
0.6
2.4
0.2
0.8
0.8
1.04

YLR273C
1.4
0.9
1.7
1.3
2.6
1.5
1.0
1.0
0.20

YGR207C
1.4
1.1
1.0
2.2
0.6
1.8
1.2
1.8
1.49

YNL037C
1.4
1.3
1.9
1.3
0.9
1.4
0.9
1.3
2.05

YOR136W
1.4
1.2
1.5
0.9
1.2
1.3
0.8
1.3
3.20

YPL271W
1.7
0.8
1.2
1.3
0.8
1.4
1.2
1.3
1.34

YAL054C
1.3
1.0
1.8
1.3
0.9
2.5
1.5
1.4
0.24

YEL011W
3.7
1.5
1.5
1.5
0.4
2.4
1.4
2.5
0.89

YFR015C
3.9
0.4
2.5
3.1
0.4
2.4
1.3
1.2
0.66

YGL253W
1.0
1.2
1.5
0.5
0.8
0.4
0.7
0.8
4.63

YIL111W
2.1
0.9
1.7
1.5
1.1
2.5
1.9
3.9
1.52

YKL150W
1.9
1.2
1.8
1.4
0.9
6.1
1.2
2.7
2.20

YPR006C
2.4
1.1
1.8
1.2
0.7
1.6
1.8
2.1
0.46

YBR145W
1.1
1.0
2.0
2.2
1.2
3.6
1.7
2.0
2.17

YBR299W
2.4
1.2
0.7
1.4
0.6
3.9
1.0
1.1
0.32

YEL020C
1.3
0.8
1.2
1.0
1.4
2.1
1.2
1.3
0.31

YGL134W
1.1
0.9
0.7
1.1
0.5
1.7
0.9
1.3
0.53

YOL157C
1.2
1.2
1.4
1.2
1.1
3.5
1.4
1.3
0.41

YBR126C
1.1
1.3
2.1
0.7
1.0
1.7
1.5
1.3
1.96

YCR005C
2.1
0.5
0.7
0.8
0.7
0.7
1.6
1.7
2.38

YIL172C
1.0
1.4
2.0
1.3
1.4
2.8
1.1
1.2
0.42

YOR221C
1.1
0.8
1.0
1.1
1.0
1.4
0.9
1.2
0.39

YBR196C
2.3
1.0
1.4
0.5
1.9
1.1
0.8
1.0
6.60

YEL047C
4.2
1.2
1.6
1.1
1.0
1.3
0.9
1.0
1.02

YMR318C
3.6
0.8
1.8
1.7
1.5
1.1
1.1
1.1
3.17

YER061C
2.2
0.7
0.9
1.0
0.8
1.8
1.2
1.2
0.84

YJL045W
2.3
1.1
1.6
1.2
3.4
2.4
0.9
0.9
0.42

YLL009C
3.5
0.7
0.9
1.4
1.1
2.8
0.9
1.2
1.66

YPR160W
4.4
2.1
2.2
1.1
1.4
5.3
1.0
2.9
1.42

YDL085W
2.7
0.8
1.7
1.2
0.7
4.5
0.9
0.9
0.23

YJL221C
0.8
1.1
1.4
1.1
1.1
3.3
1.1
1.4
0.41

YKL085W
1.8
0.8
1.5
1.0
0.5
1.7
0.9
1.3
2.16

YLR174W
1.3
1.3
1.8
1.7
0.8
4.6
0.9
1.2
0.41

YNL009W
1.3
0.9
1.3
1.3
2.7
3.3
1.2
2.3
0.45

YNL117W
1.4
0.7
1.3
2.0
2.6
1.6
1.1
0.9
0.24

YAL061W
4.1
1.1
1.4
0.7
0.6
1.1
1.4
1.2
0.88

YBR117C
0.4
0.8
2.1
0.9
1.0
12.0
0.7
0.7
0.49

YEL071W
2.1
0.9
1.6
1.2
1.6
1.2
1.1
1.2
1.13

YGR112W
1.3
0.7
1.1
1.1
1.2
2.8
0.9
1.2
0.31

YLR164W
3.2
0.7
1.0
1.5
0.7
11.0
1.5
1.2
0.31

YNR032W
1.4
0.6
1.3
1.4
0.9
1.0
1.2
1.3
0.71

YPL031C
1.4
0.8
1.6
0.9
0.7
2.0
1.4
1.2
0.49

YPR048W
1.0
0.8
0.6
1.2
0.6
0.8
0.7
0.8
0.75

YBL058W
1.3
0.8
1.6
1.3
1.8
1.8
1.0
1.4
1.42

YBR001C
1.0
1.0
2.0
1.2
1.8
1.4
1.0
1.6
0.61

YCR105W
2.3
0.9
1.9
1.9
3.1
1.3
1.3
1.1
0.36

YIR031C
1.2
0.8
1.0
1.2
0.8
0.7
0.9
0.8
0.44

YGL191W
1.6
0.9
1.1
1.6
0.7
1.8
1.2
1.7
2.35

YLR038C
1.4
0.6
0.5
1.6
0.7
2.1
1.2
2.1
1.52

YGR087C
0.8
1.2
1.2
0.7
3.5
0.6
1.0
0.6
1.88

YGL256W
1.0
0.9
0.8
0.9
1.0
0.7
0.7
0.8
0.90

YDL181W
0.8
0.9
0.9
1.1
0.4
1.1
1.5
1.4
0.85

YPL262W
1.4
1.1
1.5
1.2
0.6
1.4
1.1
1.2
0.79

YLR377C
0.6
0.6
1.2
2.9
0.8
2.7
0.9
1.4
0.14

YBR221C
1.2
1.3
1.7
0.8
1.1
1.5
0.9
1.0
3.62

YKL141W
1.2
0.8
0.8
1.4
0.6
2.8
0.9
1.8
2.84

YLR134W
1.1
1.2
1.5
0.6
1.7
0.5
0.6
0.8
3.47

YLR258W
1.2
0.9
1.4
1.2
0.6
1.7
1.0
2.0
1.36

YOR178C
4.1
1.7
1.0
1.0
1.1
1.7
1.0
1.5
0.56

YBL099W
2.1
1.0
0.9
0.6
1.0
0.9
0.7
1.2
3.49

YDR050C
2.0
1.4
2.0
1.2
1.9
1.3
1.1
2.3
6.26

YDR178W
2.0
1.3
1.5
1.5
0.7
3.0
1.2
2.3
2.27

YDR298C
1.2
1.1
1.2
1.5
0.8
2.0
1.1
1.6
2.69

YEL024W
0.9
0.8
0.6
1.1
0.6
2.1
1.1
1.5
1.59

YJL121C
1.1
0.6
0.7
0.9
1.0
0.6
1.1
1.0
1.00

YJR121W
0.9
0.8
1.0
0.7
0.9
1.2
1.1
1.4
3.99

YKL060C
2.1
1.3
1.2
0.8
1.6
1.5
1.2
1.7
6.01

YKL148C
1.5
0.8
0.8
0.8
0.6
1.1
0.8
1.0
0.54

YLL041C
1.3
0.8
1.0
1.2
0.4
3.1
1.1
1.7
1.75

YLR044C
1.1
1.4
1.7
0.5
2.2
0.6
0.9
0.9
5.16

YLR284C
1.5
0.6
0.8
1.3
1.0
4.5
2.9
8.1
0.84

YLR304C
1.6
1.0
0.5
0.7
1.6
1.8
0.5
0.7
2.39

YLR354C
1.7
1.2
1.0
0.9
2.4
1.3
1.0
1.5
4.53

YMR205C
1.0
1.1
1.3
0.5
0.9
0.9
0.6
0.5
4.75

YMR261C
0.8
0.9
1.6
0.6
0.8
1.6
0.7
1.1
0.78

YMR323W
2.5
1.2
1.8
1.2
37.3
0.6
1.1
0.6
1.04

YOL086C
2.6
1.3
1.7
0.6
1.6
1.4
1.1
1.3
4.19

YOR142W
1.5
0.8
1.4
0.8
1.1
0.8
0.9
1.0
1.31

YPL061W
1.1
1.0
1.1
0.6
1.7
1.0
1.6
2.6
3.23

YDL107W
1.0
1.0
1.2
1.5
1.0
2.0
1.1
1.5
0.51

YDR529C
0.8
0.6
0.7
1.5
0.5
1.8
1.0
2.3
3.11

YGL018C
1.1
1.0
1.3
1.2
1.1
1.5
0.8
1.0
0.36

YBR185C
1.2
0.7
1.0
1.7
1.0
1.7
0.8
1.3
0.89

YEL039C
1.7
0.6
0.5
1.4
0.4
3.5
0.7
1.1
1.59

YGR174C
1.3
0.9
1.5
1.6
0.7
3.2
1.3
2.3
1.05

YKL016C
1.3
1.0
1.3
1.6
0.7
1.8
1.0
1.7
2.08

YLR395C
1.5
0.6
0.5
1.7
0.4
1.2
1.2
2.3
1.76

YML120C
1.3
0.9
1.2
0.8
0.5
1.5
1.0
1.6
0.74

YMR073C
0.9
0.8
1.2
2.0
0.9
1.5
0.8
1.2
0.69

YOR388C
1.3
0.7
1.1
1.3
4.0
0.8
1.0
0.9
0.21

YPL275W
0.9
0.6
1.0
1.0
1.4
0.9
1.0
1.0
0.28

YPL276W
−0.4
0.6
0.9
0.9
1.0
0.6
1.1
0.8
0.22

YGL205W
0.4
1.1
1.0
1.0
2.0
4.1
3.9
9.1
0.24

YJL166W
1.4
0.7
0.8
1.9
0.5
2.3
1.7
4.0
2.31

YNL202W
1.2
0.9
1.8
1.0
1.4
4.2
2.4
3.3
0.47

YDR377W
1.4
0.9
0.7
1.4
0.6
1.8
1.2
2.5
3.00

YGL187C
0.7
0.8
0.7
0.9
0.3
1.4
0.9
2.4
2.73

YJL216C
1.1
1.0
1.1
1.1
1.2
1.5
1.2
2.0
0.25

YKR009C
1.2
1.0
1.8
1.0
1.0
4.6
1.9
2.5
0.27

YCR046C
1.5
1.1
1.5
1.3
1.4
2.8
1.3
1.0
0.63

YML129C
1.2
0.8
1.0
1.4
1.1
2.9
1.3
1.3
1.04

YPR184W
3.6
1.4
2.5
1.3
1.5
3.1
1.0
1.7
0.37

YDL067C
1.4
1.0
0.6
1.4
0.7
1.8
1.2
1.7
1.85

YDL078C
1.7
0.8
1.0
0.8
0.5
2.2
1.1
2.0
1.65

YDR079W
1.3
1.1
1.3
1.5
0.6
2.6
1.1
1.3
1.06

YGR062C
1.6
1.0
1.5
1.2
0.5
1.8
0.9
1.1
0.54

YKR058W
1.5
0.9
0.7
1.3
0.5
2.6
0.8
1.6
0.73

YLR295C
1.3
0.5
0.8
1.2
0.5
2.4
0.9
1.5
1.07

YMR267W
1.0
0.8
0.7
1.0
0.9
2.6
0.9
1.3
0.94

TABLE 5

Transport facilitation protein genes

yeast
The level of expressed mRNA in the presence of chemical substance

genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)

YBR008C
3.0
2.4
4.9
0.7
0.9
1.0
0.9
2.8
54.6
21.1

YBR296C
7.0
4.3
2.2
2.5
1.4
1.4
0.2
1.1
0.4
1.8

YDR406W
0.8
1.2
3.1
1.1
1.0
5.9
1.8
0.6
1.1
1.7

YOR153W
1.6
0.9
5.1
1.1
1.0
7.4
2.6
0.5
3.2
1.2

YGR281W
1.2
1.0
1.3
2.2
0.6
1.9
0.9
0.7
2.7
1.4

YHL047C
0.6
4.4
1.0
1.0
1.2
8.4
16.8
1.5
1.2
11.9

YBR294W
6.3
14.4
0.9
2.6
1.4
1.2
1.1
1.0
5.2
5.2

YGL006W
2.5
1.3
1.3
2.6
1.0
1.0
1.3
0.9
3.0
1.2

YGR197C
1.1
2.4
2.5
1.0
0.7
0.5
1.3
0.8
16.7
3.2

YJL034W
0.7
1.7
3.0
0.8
1.2
1.1
1.3
1.5
2.8
1.1

YNL055C
1.1
1.8
5.5
2.0
0.9
2.6
1.2
0.7
1.1
1.0

YBR052C
1.6
1.6
1.5
2.6
1.4
2.1
3.0
1.3
2.3
2.5

YBR207W
0.8
1.7
0.8
2.0
1.7
1.6
4.3
0.9
1.7
2.2

YBR293W
1.9
3.1
1.0
1.8
0.8
0.9
0.9
0.9
5.5
2.4

YDL198C
1.4
1.0
2.1
1.4
0.7
0.8
1.0
1.1
1.9
2.7

YDL245C
1.0
2.4
1.6
2.2
1.3
1.1
1.2
1.2
0.4
2.8

YDR497C
0.7
0.5
0.6
1.3
0.7
0.6
0.5
0.6
0.4
0.8

YER053C
1.6
1.8
1.9
1.7
0.6
2.8
2.8
1.3
1.3
3.9

YFL041W
0.7
1.6
1.4
1.2
1.2
2.0
3.4
1.0
0.8
5.1

YGR055W
2.5
5.7
12.0
0.7
1.3
1.1
0.6
1.1
5.0
2.4

YJL219W
1.2
2.5
3.1
1.6
1.2
1.5
0.9
1.5
4.0
2.3

YJR106W
0.9
3.8
1.5
1.1
0.9
1.2
1.0
0.9
2.0
1.6

YKL146W
0.8
1.3
1.3
0.9
1.0
1.3
0.9
0.8
4.6
2.8

YLL028W
0.6
0.9
4.6
0.5
0.9
1.7
1.0
0.7
1.2
2.3

YLR348C
1.1
4.5
1.2
1.2
0.9
1.9
0.9
0.9
2.1
1.3

YOL119C
2.6
4.8
1.5
2.3
1.5
0.9
2.2
2.0
5.0
7.4

YOL163W
1.5
3.2
2.1
3.3
0.9
0.5
0.9
1.1
7.5
6.2

YOR035C
1.2
1.2
0.3
1.2
1.0
1.9
1.3
1.0
1.3
1.7

YOR130C
0.8
1.7
1.4
1.0
1.8
1.6
1.3
0.8
2.0
1.7

YOR273C
0.7
1.0
1.7
1.0
1.1
0.4
0.4
0.6
0.6
0.5

YOR332W
1.1
1.0
1.0
1.0
0.9
1.8
0.9
1.5
1.8
1.1

YCR098C
1.6
3.0
1.7
2.0
1.4
1.6
1.2
1.0
1.4
2.4

YGR138C
1.1
1.6
1.0
1.2
0.8
0.8
0.7
1.0
0.5
1.0

YBR295W
1.4
1.5
3.3
1.1
0.8

1.6
0.9
1.2
3.3

YGL255W
0.7
0.9
0.9
0.8
1.4
1.1
1.0
0.7
0.3
5.0

YHL035C
0.7
1.3
0.9
1.9
0.9
4.1
1.7
1.1
0.6
4.6

YIL022W
0.8
0.7
1.1
1.6
0.8
1.2
0.7
0.8
1.1
1.3

YLR378C
0.7
0.9
2.6
0.5
1.0
1.2
0.7
0.5
1.1
0.7

YCL038C
1.6
1.6
1.4
1.6
1.2
3.2
1.5
1.2
1.1
0.9

YFL054C
1.6
1.1
1.4
2.2
1.3
2.4
1.1
1.5
2.0
2.3

YHL040C
1.6
4.9
1.5
0.4
1.1
7.3
4.0
1.5
1.1
11.3

YKR039W
1.4
3.5
1.3
1.7
1.0
2.8
1.0
1.0
1.9
2.0

YPL271W
1.2
3.2
4.1
1.2
1.4
3.3
1.2
0.9
0.6
1.2

YBR068C
1.1
1.0
1.9
2.5
1.4
1.9

1.0
0.8
2.5

YCR037C
0.7
1.0
0.8
0.8
1.3
1.8
1.0
0.7
0.6
0.6

YDL128W
0.8
1.1
2.1
1.0
1.0
2.3
0.9
0.8
0.5
0.7

YDR270W
0.7
1.5
1.4
1.3
1.0
2.2
1.7
1.2
2.9
3.6

YEL065W
0.3
3.8
1.2
0.4
1.4
2.3
4.3
0.9
0.1
4.9

YGL008C
0.6
0.7
3.1
0.9
0.8
1.9
1.4
0.7
0.0
0.4

YGL104C
0.8
2.0
2.1
1.8
1.0
2.1
1.2
0.8
4.6
2.1

YGL167C
0.9
0.7
1.6
1.3
1.2
2.0
1.2
0.8
1.3
1.1

YGR065C
0.8
1.5
2.6
1.1
1.2
2.4
2.4
1.0
1.2
2.6

YHR092C
2.3
1.0
7.5
2.5
1.4
1.7
0.5
1.5
0.2
0.9

YIL088C
0.9
2.1
2.1
1.3
1.6
2.2
1.7
0.8
1.0
1.7

YNL259C
1.6
3.5
1.1
1.2
1.1
3.9
3.8
1.5
1.6
2.1

YOR270C
0.7
0.5
2.0
0.8
0.8
1.8
1.0
0.6
0.4
0.9

YPL265W
0.7
0.4
2.3
1.1
1.0
2.3
8.9
2.3
0.2
1.2

YPR124W
0.2
0.4
0.3
1.4
2.0
2.0
2.9
2.7
0.2
1.5

YER119C
0.7
2.1
1.8
0.7
0.8
1.3
0.8
0.6
5.8
1.2

YFL055W
2.0
6.7
1.3
2.5
1.5
1.1
1.4
1.3
23.9
6.5

YLL055W
2.6
19.0
4.8
1.7
1.0
1.4
1.7
1.4
19.1
14.0

YHL036W
2.2
4.8
3.4
2.0
1.3
1.3
1.0
1.2
9.0
4.4

YHR048W
2.5
1.4
1.4
1.7
1.0
0.8
0.8
1.9
4.5
2.7

YKL221W
1.3
0.7
2.0
1.0
1.0
0.9
1.3
1.2
7.3
2.7

YLR092W
5.0
5.6
1.4
0.6
1.3
1.0
1.3
1.5
12.7
5.8

YML116W
4.1
1.3
1.5
1.4
1.2
0.9
1.4
2.2
1.4
3.1

YBR291C
2.0
0.9
1.0
1.5
0.9
1.1
0.9
2.2
0.9
1.0

YCL069W
0.9
4.5
0.9
0.8
0.9

1.4
1.3
1.2
6.9

YJR095W
1.2
20.5
1.9
6.7
1.2
1.5
2.0
0.9
0.5
6.3

YKL188C
1.3
0.7
1.9
2.4
1.0
0.8
1.1
0.7
2.5
2.8

YKL217W
1.8
2.4
1.0
2.1
1.1
1.2
1.6
1.1
0.9
4.1

YKR105C
0.8
0.9
0.9
1.5
1.0
1.2
1.0
1.3
1.0
5.2

YOL158C
0.7
4.0
2.4
0.9
1.2
2.0
1.6
0.7
1.7
6.1

YPL224C
1.0
2.2
1.3
2.5
0.6
1.3
2.2
1.3
3.2
4.2

YPR201W
33.2
0.9
1.1
1.0
1.2
1.9
0.8
0.9
8.3
5.6

YAL067C
2.7
12.1
1.5
1.4
0.7
1.2
0.8
1.1
7.6
2.9

YDL149W
0.8
2.0
1.2
1.6
1.5
1.0
0.7
1.2
3.2
2.0

YJL094C
1.0
1.7
1.3
2.0
1.4
1.3
1.7
0.8
5.4
2.9

YLL061W
3.6
2.8
9.2
0.4
0.8
0.8
0.9
1.4
3.7
5.5

YPL274W
0.8
4.2
3.8
0.8
0.6
1.1
0.7
0.9
4.1
3.6

YBR241C
0.9
9.3
2.6
0.9
0.9
1.5
1.4
0.7
29.8
2.2

YDL206W
0.9
1.7
1.8
1.4
1.1
5.7
2.0
1.1
1.6
1.5

YDR040C
0.7
1.4
3.7
0.8
1.0
1.7
0.7
0.8
2.0
1.2

YFR045W
1.1
1.6
1.1
1.1
1.0
1.0
0.6
1.0
2.2
1.0

YIL170W
1.1
1.0
2.5
2.2
0.9
8.8
0.5
1.2
5.7
3.2

YKL192C
1.1
1.0
3.7
1.1
1.1
1.8
1.1
0.9
3.5
1.6

YKL209C
1.0
1.0
1.3
0.8
1.2
3.3
0.9
1.4
2.4
1.6

YKR106W
1.3
0.8
2.1
1.4
1.2
1.6
0.9
1.3
10.5
7.4

YMR056C
1.1
1.3
1.7
1.0
1.1
0.9
1.4
1.2
1.8
1.1

YPL147W
1.0
0.8
2.3
1.2
1.2
1.1
1.0
0.9
2.4
2.4

YIL166C
1.9
12.5
2.1
1.2
1.0
1.9

1.3
2.5
2.9

YMR058W
0.3
5.1
2.1
0.3
0.8
2.6
1.8
0.8
0.2
1.4

YNL142W
0.7
2.4
2.5
0.8
1.3
0.9
1.1
0.8
0.9
0.6

YDL210W
1.2
2.2
2.7
1.1
0.9
1.3
0.8
1.1
1.2
1.4

YCL025C
1.1
4.6
2.5
1.7
0.9
0.9
0.7
0.7
0.3
0.3

YJL212C
0.8
3.2
3.1
0.5
1.2
1.1
0.7
0.7
1.1
1.3

YBR132C
0.9
1.9
2.4
1.8
0.8
1.2
1.1
0.8
0.8
1.1

YBL030C
1.0
0.9
4.5
0.9
0.7
1.1
0.9
0.8
0.4
0.9

YCR024C-A
0.8
0.9
3.2

0.9
1.2
0.8
0.8
0.2
0.7

YDR342C
2.8
1.1
12.2
5.7
1.6
1.1
0.8
1.2
0.2
2.2

YDR343C
1.2
1.0
20.6
4.6
1.3
1.3
0.7
1.2
0.3
2.1

YEL027W
1.2
0.6
3.4
1.1
1.0
1.1
0.8
0.9
0.9
1.1

YHR094C
0.7
1.2
5.3
1.6
1.1
1.6
0.8
1.2
0.3
1.2

YHR175W
0.8
2.0
2.4
1.5
0.9
1.0
1.6
0.9
0.6
2.0

YIL056W
1.1
0.9
6.2
1.4
1.2
1.0
0.6
0.7
1.2
1.6

YMR203W
0.8
0.7
3.0
1.4
0.6
1.1
0.8
0.7
0.7
1.2

YBL099W
0.8
0.9
3.1
1.4
1.0
0.9
0.9
0.8
0.9
0.7

YBR127C
0.8
0.7
2.2
1.1
1.4
1.1
0.9
1.1
0.6
1.3

YDR038C
0.6
1.3
3.1
0.9
0.9
1.8
0.7
0.9
1.4
0.9

YDR039C
0.6
1.6
3.2
0.9
1.3
1.1
0.8
0.6
1.8
1.0

YDR298C
1.3
1.2
2.6
1.3
1.3
1.2
1.0
1.2
1.0
1.6

YDR345C
0.8
0.9
5.6
2.6
1.3
1.2
1.1
1.2
0.2
1.1

YEL063C
0.7
0.8
2.4
1.3
1.2
1.3
0.7
0.6
0.8
1.7

YFL011W
1.2
0.7
3.7
3.3
1.3
1.0
0.8
0.8
0.3
1.6

YGR082W
1.0
0.9
2.2
1.0
0.9
1.1
0.9
0.8
0.6
0.9

YGR191W
0.8
0.7
1.6
1.5
0.8
1.1
0.7
0.7
0.1
0.7

YGR260W
0.6
0.7
3.4
0.8
0.8
0.9
0.9
0.5
0.3
0.4

YHR026W
0.9
1.0
1.9
1.0
1.1
1.3
0.9
1.6
1.1
0.9

YJR077C
1.1
1.1
2.0
1.6
0.9
0.9
0.7
0.8
0.4
0.7

YJR121W
0.9
1.1
3.3
1.0
0.8
1.5
1.0
0.7
0.8
1.3

YLR081W
1.3
0.8
2.8
3.6
1.0
0.9
0.7
0.9
0.1
2.2

YMR011W
1.3
1.0
9.4
5.5
0.9
0.6
0.8
1.1
0.0
0.7

YOL156W
1.1
0.7
2.5
1.1
1.2
1.2
1.0
1.0
2.3
2.1

YPL036W
0.5
0.8
2.8
0.9
1.3
0.7
0.3
0.5
0.1
0.3

YGR096W
1.5
1.0
1.1
4.6
1.2
1.7
0.9
1.0
0.8
0.8

YIL006W
1.0
1.1
1.4
2.9
0.8
0.3
0.8
0.6
0.9
1.1

YKL016C
1.5
1.3
0.7
1.7
1.5
0.8
1.5
1.6
1.3
1.8

YKR067W
0.8
2.6
1.5
2.5
1.3
1.8
2.0
0.8
1.6
2.3

YMR162C
0.8
1.1
1.1
2.0
0.9
1.0
0.8
0.8
0.7
1.0

YOR348C
1.1
0.7
1.2
2.0
0.9
0.7
0.8
0.8
0.5
0.4

YPR192W
0.9
1.1
0.9
5.0
1.2
0.9
0.9
0.6
0.7
1.3

YPR194C
2.2
1.4
0.5
2.9
1.3
1.5
0.7
1.0
0.5
0.6

YDR086C
1.3
1.0
1.2
1.4
1.0
0.8
2.0
1.9
0.6
0.8

YGR224W
0.9
1.2
1.2
1.2
1.4
0.8
0.4
0.6
0.9
0.9

YDR387C
0.8
0.9
1.2
2.2
0.9
1.2
1.3
0.7
1.4
2.0

YFL050C
0.7
1.0
1.1
2.2
1.0
0.9
0.8
0.9
0.5
1.6

YBR298C
1.1
1.0
1.6
2.3
1.4
0.4
1.7
0.5
0.3
1.1

YLR295C
1.4
1.1
1.1
1.7
2.2
1.1
1.1
1.2
1.4
1.2

YNR072W
1.1
1.5
0.5
0.7
1.0
0.9
1.5
0.9
0.7
1.8

YOR316C
0.7
2.5
1.5
1.5
1.0
0.9
1.4
0.8
1.6
2.0

YOR328W
1.0
1.0

1.0
1.0
2.9

YPL134C
1.5
1.0
1.6
1.6
1.4
1.2
1.2
1.3
0.6
0.8

yeast
The level of expressed mRNA in the absence of chemical substance

genes
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity

YBR008C
9.4
0.8
2.0
4.1
0.8
3.1
2.0
1.2
0.37

YBR296C
1.5
1.6
2.0
2.3
1.7
0.3
3.8
4.0
0.54

YDR406W
1.4
3.9
7.7
0.5
0.8
5.5
2.7
5.6
0.53

YOR153W
1.0
4.0
11.8
0.3
3.6
1.6
2.5
3.1
1.91

YGR281W
0.7
2.4
12.9
0.9
2.1
1.1
2.8
3.1
1.04

YHL047C
1.0
2.6
3.8
0.5
1.1
2.3
1.2
1.2
0.74

YBR294W
1.2
1.0
3.1
1.3
1.0
0.9
1.0
0.9
0.18

YGL006W
0.8
0.9
4.5
0.9
1.1
1.7
2.4
4.1
1.37

YGR197C
1.1
1.2
2.4
1.5
1.0
1.5
1.7
1.9
0.37

YJL034W
1.3
1.6
6.1
0.6
7.9
0.6
1.1
1.0
4.58

YNL055C
1.9
1.7
2.4
0.9
1.1
2.6
1.2
1.7
4.10

YBR052C
1.7
1.3
2.1
1.5
0.7
3.1
1.8
3.1
2.77

YBR207W
1.1
0.9
2.2
0.9
1.4
1.4
1.2
1.4
1.39

YBR293W
1.1
1.0
3.0
1.4
3.1
1.6
1.0
0.9
0.94

YDL198C
2.5
1.2
2.0
1.7
1.2
1.4
1.5
1.1
1.19

YDL245C
1.5
1.0
2.0
1.2
1.8
1.5
1.0
1.1
0.28

YDR497C
0.7
0.9
2.7
0.6
10.1

1.6
1.8
1.45

YER053C
2.4
1.7
4.1
1.3
1.1
2.8
1.2
2.3
1.83

YFL041W
0.9
1.1
1.8
1.0
0.9
1.4
1.1
0.9
0.89

YGR055W
1.5
0.9
1.9
1.2
2.1
0.6
0.7
0.7
1.42

YJL219W
2.3
1.1
4.0
1.1
2.6
1.4
1.6
1.2
0.91

YJR106W
1.6
0.9
3.5
0.9
1.2
1.9
1.2
1.3
0.29

YKL146W
0.9
1.1
2.7
1.0
1.5
1.3
1.0
0.9
0.42

YLL028W
0.7
1.3
4.1
0.7
3.1
0.6
1.2
1.2
1.02

YLR348C
1.3
0.9
1.9
1.0
2.4
1.1
1.1
1.0
0.64

YOL119C
3.4
0.9
1.6
2.4
4.7
2.8
1.4
1.0
0.37

YOL163W
1.6
1.0
2.4
1.2
1.0
1.4
0.8
0.8
0.30

YOR035C
1.0
1.1
2.5
0.9
3.8
1.8
1.6
2.1
0.52

YOR130C
0.6
0.9
2.1
1.3
1.0
0.8
1.5
1.1
0.51

YOR273C
1.5
0.8
2.6
0.5
0.8
0.6
3.2
3.1
1.20

YOR332W
1.5
1.0
2.2
1.1
1.2
1.2
1.3
1.7
3.58

YCR098C
1.3
1.3
1.4
1.1
11.0
0.8
1.7
1.6
0.22

YGR138C
0.7
0.6
0.6
0.9
4.5
0.7
0.7
0.7
1.24

YBR295W
1.1
0.9
1.8
1.1
4.8
1.4
1.3
1.2
0.27

YGL255W
0.5
0.7
0.2
1.0
2.6
0.5
0.6
0.5
1.36

YHL035C
0.9
1.4
1.1
0.8
3.1
2.4
1.1
1.2
0.77

YIL022W
1.0
0.9
1.2
0.6
2.9
1.1
0.8
0.7
0.52

YLR378C
1.0
1.2
1.6
0.4
5.9
0.4
0.9
0.7
1.23

YCL038C
2.0
1.3
1.9
1.3
2.0
1.8
1.4
1.5
1.04

YFL054C
1.7
1.2
2.3
0.9
1.4
1.3
1.7
1.4
1.06

YHL040C
1.7
2.0
2.0
1.1
3.4
1.0
1.4
1.0
0.69

YKR039W
1.9
1.5
1.3
1.2
1.7
1.9
0.9
1.1
0.40

YPL271W
1.7
0.8
1.2
1.3
0.8
1.4
1.2
1.3
1.34

YBR068C
0.8
0.8
2.2
1.8
1.6
5.5
1.1
1.3
1.99

YCR037C
0.8
0.7
1.3
0.8
1.0
1.1
1.4
0.9
0.74

YDL128W
1.2
0.9
1.6
0.7
1.1
1.0
0.9
1.0
2.80

YDR270W
1.0
1.0
1.8
1.0
1.4
1.1
0.9
0.7
0.38

YEL065W
0.6
1.7
0.8
0.4
2.2
2.6
0.7
0.6
2.10

YGL008C
0.7
2.4
1.9
1.2
1.0
2.1
1.1
1.0
4.08

YGL104C
1.8
1.1
2.0
1.0
0.9
1.7
1.3
1.3
0.58

YGL167C
0.8
1.1
1.5
0.8
1.3
1.3
1.4
1.4
1.41

YGR065C
1.1
0.5
0.8
1.3
1.2
1.1
0.7
0.7
0.68

YHR092C
1.5
1.0
0.5
1.6
0.2
1.2
0.9
1.3
6.09

YIL088C
1.8
0.9
1.5
1.2
1.2
1.8
1.2
1.4
1.89

YNL259C
1.6
0.7
1.1
1.4
0.7
1.7
2.6
2.4
1.22

YOR270C
1.5
0.7
1.3
0.7
1.1
0.8
0.9
0.9
3.49

YPL265W
1.8
0.9
1.1
1.1
1.2
2.0
0.5
0.4
1.42

YPR124W
2.0
0.8
0.6
0.4
1.1
2.4
1.0
1.3
2.57

YER119C
2.2
0.7
1.6
1.0
2.3
0.8
1.0
0.9
0.32

YFL055W
2.7
0.9
1.3
1.5
0.7
1.4
1.4
1.0
0.23

YLL055W
3.6
0.7
1.5
1.3
0.7
2.8
1.1
1.3
0.47

YHL036W
2.3
1.2
1.5
1.2
0.9
1.1
1.0
1.0
0.60

YHR048W
2.0
0.9
1.1
1.7
0.9
1.4
0.7
0.9
0.26

YKL221W
1.9
0.7
1.6
1.4
1.1
1.3
0.8
0.9
0.27

YLR092W
3.1
1.0
1.8
1.4
0.9
1.2
1.0
1.1
0.24

YML116W
4.3
0.5
0.8
2.0
1.9
1.0
1.0
1.0
0.94

YBR291C
1.1
0.9
1.0
1.7
0.5
1.5
0.9
1.3
1.19

YCL069W
1.0
0.9
0.8
1.3
1.4
0.9
1.0
1.0
0.25

YJR095W
0.6
0.7
0.8
1.3
0.8
0.8
1.3
0.9
0.23

YKL188C
1.1
1.2
1.2
2.1
1.4
2.7
1.1
1.5
0.27

YKL217W
1.6
0.8
1.2
1.2
2.2
3.0
1.7
3.3
0.29

YKR105C
0.0
0.8
2.5
1.2
1.5
0.7
0.8
1.0
0.26

YOL158C
0.7
0.9
1.4
1.0
0.9
1.2
1.4
1.7
1.30

YPL224C
0.8
1.1
1.3
1.4
1.0
2.5
1.3
1.9
0.64

YPR201W
2.2
0.7
1.1
1.8
0.8
0.9
0.8
0.9
0.29

YAL067C
1.2
1.0
1.1
1.3
2.4
1.6
1.0
1.0
0.33

YDL149W
1.2
0.7
1.5
1.2
1.8
1.4
0.8
1.0
0.33

YJL094C
1.1
1.2
2.6
1.0
1.0
1.8
2.1
2.0
0.84

YLL061W
1.7
0.7
0.9
1.3
1.4
1.0
0.6
0.7
0.33

YPL274W
2.0
0.5
0.6
0.9
1.5
1.1
0.7
0.6
0.41

YBR241C
1.4
1.4
1.4
0.9
1.6
0.7
1.0
1.2
1.25

YDL206W
0.6
1.0
1.3
1.0
1.1
3.1
1.0
1.1
0.35

YDR040C
0.8
0.9
1.8
0.9
0.8
1.4
1.4
1.6
1.25

YFR045W
1.4
1.0
1.1
1.0
1.1
0.6
0.9
0.8
0.84

YIL170W
1.7
0.7
1.9
1.1
2.3
1.8
1.6
1.5
0.48

YKL192C
1.1
1.2
1.7
1.5
1.2
2.1
1.0
0.8
1.57

YKL209C
0.8
0.9
1.4
1.1
1.0
1.1
1.1
1.0
0.30

YKR106W
1.8
0.8
1.4
1.7

2.8
0.9
0.8
0.16

YMR056C
1.6
0.9
0.9
1.1
0.7
2.4
1.0
1.1
0.72

YPL147W
1.3
0.9
1.5
1.0
2.4
2.5
1.5
3.6
0.33

YIL166C
1.8
0.9
1.5
1.1
1.3
0.7
1.2
0.9
0.26

YMR058W
0.8
0.8
0.4
0.3
0.5
0.4
0.6
0.5
1.66

YNL142W
0.9
1.2
0.9
0.8
0.3
1.0
1.0
0.9
0.44

YDL210W
0.6
0.8
1.2
1.1
1.9
0.9
1.1
0.9
0.20

YCL025C
1.0
1.1
0.5
0.7
0.8
0.6
0.6
0.6
1.98

YJL212C
0.9
0.4
1.0
0.8
0.3
0.5
0.6
0.5
0.59

YBR132C
1.9
1.0
1.4
1.1
1.5
1.3
1.1
1.3
0.43

YBL030C
1.1
0.9
0.5
0.8
1.8
1.0
1.0
1.1
3.12

YCR024C-A
1.5
1.0
0.5
0.8
1.3
1.5
0.9
1.4
4.02

YDR342C
2.9
1.0
0.6
0.9
0.5
2.4
1.0
2.2
5.23

YDR343C
2.3
1.0
0.8
0.8
0.5
2.8
1.1
2.3
5.81

YEL027W
0.9
0.9
0.7
1.4
1.5
1.6
1.0
1.4
4.75

YHR094C
0.6
0.9
0.7
0.6
2.7
0.9
1.4
1.4
4.82

YHR175W
1.1
1.4
1.2
0.7
1.3
2.3
1.3
1.2
1.01

YIL056W
0.7
1.0
1.5
1.0
0.5
0.9
1.5
1.2
0.71

YMR203W
2.3
0.7
1.1
0.7
1.2
0.9
0.8
0.7
1.62

YBL099W
2.1
1.0
0.9
0.6
1.0
0.9
0.7
1.2
3.49

YBR127C
1.1
0.9
0.9
0.6
1.3
1.4
0.8
1.0
4.59

YDR038C
0.9
0.7
2.0
0.8
0.8
1.4
1.3
1.5
1.32

YDR039C
0.9
0.8
1.8
0.9
1.2
1.4
1.1
1.6
1.39

YDR298C
1.2
1.1
1.2
1.5
0.8
2.0
1.1
1.6
2.69

YDR345C
1.5
1.4
1.2
0.8
0.8
1.0
1.3
1.8
5.65

YEL063C
0.8
1.1
1.1
0.8
1.3
1.0
0.7
0.7
1.12

YFL011W
2.1
0.9
0.8
0.8
1.7
1.2
0.8
1.0
1.25

YGR082W
1.3
0.8
0.5
0.9
1.2
1.3
0.9
0.8
1.47

YGR191W
1.6
0.7
1.0
0.7
1.5
0.7
0.8
0.8
1.58

YGR260W
1.3
0.6
0.5
0.7
1.8
1.0
0.9
0.9
1.71

YHR026W
1.4
0.7
0.7
1.3
2.4
1.2
0.9
1.1
3.40

YJR077C
1.6
1.0
0.9
0.7
1.5
0.7
1.0
0.8
1.79

YJR121W
0.9
0.8
1.0
0.7
0.9
1.2
1.1
1.4
3.99

YLR081W
2.6
1.0
0.6
1.0
0.7
1.2
0.7
0.9
1.46

YMR011W
1.5
0.8
0.4
0.6
0.6
1.2
1.3
1.6
4.95

YOL156W
1.1
0.9
1.7
0.9
1.9
0.9
0.9
0.9
0.53

YPL036W
0.8
0.5
0.3
0.6
1.0
0.7
0.4
0.5
3.66

YGR096W
0.8
0.8
1.1
1.2
0.9
0.8
0.8
1.0
0.49

YIL006W
1.0
0.9
0.8
1.0
1.5
1.7
0.8
0.9
0.28

YKL016C
1.3
1.0
1.3
1.6
0.7
1.8
1.0
1.7
2.08

YKR067W
1.3
1.0
1.3
1.3
1.3
2.0
0.8
1.0
0.58

YMR162C
1.7
0.7
0.9
1.0
1.0
0.8
0.8
1.1
0.32

YOR348C
1.1
0.7
1.1
1.2
1.6
1.7
0.9
0.9
0.18

YPR192W
0.7
0.5
1.1
0.7
1.7
2.6
1.6
0.9
0.28

YPR194C
0.7
0.7
1.0
1.0
0.4
0.8
1.0
0.9
0.27

YDR086C
1.1
0.7
0.7
1.5
2.1
1.3
1.4
1.9
2.60

YGR224W
0.8
0.6
0.8
0.9
1.1
1.0
2.8
1.3
0.27

YDR387C
2.0
0.9
1.3
0.9
1.4
2.7
1.2
1.1
0.86

YFL050C
1.2
0.9
1.2
1.0
1.4
2.3
0.8
1.0
0.36

YBR298C
1.5
1.1
0.8
0.9
0.2
2.1
0.9
0.8
0.88

YLR295C
1.3
0.5
0.8
1.2
0.5
2.4
0.9
1.5
1.07

YNR072W
1.4
1.0
1.5
1.0
1.8
2.1
1.3
1.0
0.26

YOR316C
2.4
1.1
1.6
1.0
1.5
2.2
0.8
1.0
0.93

YOR328W
1.1
1.8

0.8
3.3
2.1

0.19

YPL134C
1.7
0.8
1.0
1.4
1.1
3.3
1.3
1.3
0.70

TABLE 6

Stress protein genes

The level of expressed mRNA in the presence of chemical substance/The level of expressed mRNA in the absence of chemical substance

yeast genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity

YBR072W
18.5
17.4
18.4
10.5
1.2
32.2
6.6
2.1
29.4
43.4
6.3
16.3
38.5
5.8
4.9
23.1
1.8
2.2
0.59

YFL014W
3.4
5.1
5.7
11.0
1.0
9.3
5.5
3.4
13.1
5.8
5.0
4.3
15.2
7.3
6.3
14.2
1.5
8.8
2.14

YLL060C
12.5
4.2
2.3
2.6
0.9
1.4
2.0
5.8
13.0
23.2
14.1
1.1
1.8
10.6
1.5
3.6
1.9
2.3
0.57

YAL005C
0.6
1.6
7.0
0.9
1.2
1.6
1.2
0.9
3.9
1.8
1.0
1.2
5.0
0.4
1.6
0.7
0.8
0.5
5.23

YBL075C
1.3
4.3
3.1
1.6
1.1
0.8
1.3
0.8
60.3
6.7
1.6
1.1
8.0
1.1
2.6
2.2
1.2
0.7
1.17

YBR169C
1.0
2.1
3.9
1.9
0.8
4.9
2.5
0.9
7.0
4.3
2.2
1.7
7.2
1.1
1.6
2.4
1.3
1.6
1.10

YCL035C
2.0
2.3
1.5
1.7
1.5
5.1
2.7
1.4
1.9
2.3
2.1
1.5
2.8
2.5
1.9
5.5
2.6
4.2
1.74

YCR060W

0.7
0.9

0.8
3.3
2.4
1.2
0.7
1.1
1.2
1.7
8.6
1.7

3.3
1.2
1.7
1.04

YDR155C
1.1
1.5
3.2
1.8
0.8
1.5
1.2
1.4
1.3
1.3
3.8
1.4
3.3
1.0
2.5
1.6
1.2
2.5
4.99

YDR258C
1.6
2.3
2.8
1.4
1.3
2.4
3.9
1.9
4.9
13.3
1.7
1.8
5.2
1.5
0.6
1.0
1.3
1.3
0.87

YER103W
0.7
2.1
5.2
2.1
1.1
1.7
1.0
0.9
20.3
9.0
1.8
1.9
9.0
0.9
3.2
1.2
1.4
0.6
2.10

YKL210W
0.5
1.7
2.7
0.7
0.8
1.4
1.0
0.9
3.5
2.9
1.4
1.3
2.9
0.8
1.0
0.9
0.7
1.1
2.29

YLL024C
0.5
1.6
5.3
0.8
0.7
1.0
1.1
0.7
2.8
2.4
1.6
1.0
4.8
0.4
1.3
0.5
0.5
0.6
5.12

YLL026W
1.8
2.9
7.7
1.7
0.9
1.9
2.9
1.4
11.4
6.6
1.7
1.9
8.1
0.8
0.9
1.6
1.7
2.5
2.56

YNL160W
2.1
3.7
10.6
2.0
1.3
5.8
2.4
1.2
3.5
2.7
5.4
1.4
6.0
1.3
0.7
4.0
1.0
1.0
1.77

YNL241C
1.3
2.5
4.3
1.0
0.8
0.9
3.2
0.9
3.4
7.4
3.0
2.0
4.9
1.1
7.0
2.8
1.0
1.0
0.68

YOR027W
0.7
2.4
4.4
0.8
1.0
1.6
1.3
0.9
3.5
4.0
1.3
1.3
5.1
0.8
1.4
0.6
0.9
0.8
1.52

YPL240C
0.7
1.4
2.4
0.9
1.3
1.2
1.4
1.2
3.5
2.6
1.0
0.8
2.9
0.7
1.2
0.7
0.8
1.0
4.83

YDR293C
0.9
0.9
1.2
1.4
0.6
0.9
0.9
0.6
1.2
1.2
1.1
0.9
2.3
0.8
1.7
1.6
1.4
1.3
1.12

YDR436W
0.9
0.9
1.1
1.4
0.7
1.1
1.2
0.9
3.5
1.1
2.0
0.9
2.7
1.2
0.8
1.4
0.9
1.2
0.53

YDR519W
1.3
3.2
1.7
1.6
0.7
1.3
1.9
1.4
0.5
1.2
1.2
1.7
2.5
1.3
2.0
1.5
1.8
2.4
2.01

YEL030W
0.7
0.9
1.9
1.1
0.4
0.6
0.9
0.7
2.3
2.5
1.7
0.9
2.7
0.7
0.8
0.8
0.9
0.6
1.28

YER125W
0.6
1.1
1.5
0.9
1.4
0.7
0.8
0.7
0.6
1.2
1.0
0.7
1.9
0.7
0.8
1.0
1.0
1.0
1.48

YFL016C
0.8
1.0
1.6
0.9
1.3
1.3
1.4
0.7
6.4
2.9
1.2
1.0
2.8
0.8
0.8
0.6
1.2
0.9
1.25

YFR052W
1.1
1.6
1.3
1.5
1.4
3.2
2.2
1.5
3.7
3.0
0.9
1.8
3.8
3.3
1.4
2.7
1.2
1.9
1.62

YHR057C
1.1
1.2
0.7
0.9
1.3
1.3
1.3
1.0
2.6
1.2
1.6
1.1
1.9
1.9
1.2
2.2
1.6
1.3
1.07

YIR037W
1.4
2.2
2.0
2.3
0.6
2.7
1.8
1.3
6.2
3.8
3.0
1.3
2.4
2.3
1.0
4.0
1.7
2.9
1.97

YIR038C
1.3
3.5
4.6
2.0
0.7
2.5
2.0
1.3
4.6
4.5
3.4
1.1
2.5
2.5
1.2
6.0
2.8
2.0
1.11

YJR045C
0.5
1.9
3.9

0.5
1.2
1.0
0.8
3.2
3.0
1.4
1.0
2.3
0.5
2.3
0.8
0.7
0.9
3.78

YLL039C
1.1
1.0
1.7
1.2
0.9
1.5
1.1
1.1
3.4
1.5
1.1
1.0
2.2
1.4
3.0
1.1
1.6
2.1
3.60

YLR259C
0.7
1.0
3.1
1.6
1.1
0.9
1.8
0.8
1.8
2.6
3.0
0.7
2.5
0.8
2.1
1.3
0.8
1.0
2.09

YML070W
0.9
1.7
2.5
1.9
1.4
2.2
3.1
1.3
4.5
3.9
1.5
1.3
3.3
1.3
0.9
2.6
1.2
1.3
1.03

YPL106C
0.6
1.7
2.4
1.1
1.2
1.6
1.1
1.2
4.9
1.8
1.3
1.1
3.1
0.9
1.1
0.5
0.5
0.5
3.34

YPR026W
0.9
1.2
5.0
1.3
0.8

1.3
1.0
0.9
3.1
1.6
1.2
2.3
1.5
3.1
2.5
0.9
1.3
0.26

YDR077W
1.2
1.0
3.5
2.1
0.8
1.0
0.7
0.8
0.7
0.7
6.8
0.8
1.0
0.3
6.1
1.0
1.4
1.1
4.77

YKL163W
1.1
1.4
3.4
1.9
0.6
1.1
0.9
0.8
0.7
1.6
1.3
0.9
1.5
0.5
16.8
3.0
0.8
1.0
2.01

YLR109W
0.8
2.9
6.0
0.9
1.3
2.1
2.6
0.9
2.4
2.7
1.5
1.6
3.2
2.3
3.9
1.8
1.1
1.2
3.86

YOR208W
1.3
1.0
1.2
2.9
1.4
1.8
1.1
1.0
1.5
2.0
1.2
1.2
1.5
1.3
4.4
1.9
1.6
1.6
0.56

YDR098C
0.8
1.4
1.0
0.8
1.5
1.1
1.5
1.2
3.7
1.5
1.4
1.3
1.2
1.5
2.2
0.8
1.0
1.2
1.59

YHR030C
2.1
0.8
0.6
2.9
1.8
0.9
1.8
1.5
0.6
2.5
1.5
0.7
1.0
1.1
3.4
1.4
2.0
1.8
1.05

YJL159W
1.0
1.3
2.8
1.1
1.0
1.8
0.9
0.8
0.5
1.2
1.2
1.0
1.7
0.6
5.3
1.0
1.4
0.9
2.45

YMR173W
1.5
3.6
3.0
0.9
1.1
5.0
2.4
2.3
2.7
8.2
3.2
1.4
2.0
2.3
2.5
1.2
1.9
1.8
1.37

YCR021C
5.2
1.4
4.2
8.6
0.9
2.2
0.9
0.8
2.2
1.0
0.6
0.5
0.9
1.6
0.5
0.6
0.7
0.8
1.36

YDL022W
0.9
2.6
6.9
1.5
0.7
2.1
1.5
0.8
1.2
1.8
2.8
1.2
1.5
0.8
0.9
1.1
1.0
1.4
1.79

YDR033W
1.1
1.3
4.6
1.5
1.1
6.7
0.8
1.0
0.3
1.0
0.7
1.0
0.7
1.0
0.8
1.0
0.7
1.0
5.78

YFL020C
1.0
1.1
1.9
1.2
1.1
2.0
1.4
0.7
1.3
1.4
1.2
1.3
1.4
1.0
1.4
0.9
1.5
0.9
0.70

YGL073W
1.0
2.1
0.9
1.0
1.7
1.9
1.3
0.8
1.9
2.4
0.8
0.8
1.5
1.2
0.9
1.1
2.5
1.2
0.66

YIL033C
0.8
1.3
3.3
1.3
0.7
2.0
1.1
0.7
2.4
1.3
1.8
1.1
2.5
0.7
1.0
2.0
1.0
1.2
1.18

YMR021C
1.0
0.7
0.9
1.1
1.6
2.2
2.5
1.3
0.6
1.3
0.9
0.8
1.4
1.3
1.0
2.0
3.3
3.4
1.14

YBR126C
0.8
1.9
5.6
1.2
0.7
2.9
2.3
0.6
1.7

1.1
1.3
2.1
0.7
1.0
1.7
1.5
1.3
1.96

YBR067C
1.6
2.5
2.8
0.9
1.1
1.1
1.1
1.1
1.7
1.0
3.1
1.0
0.9
0.7
3.3
2.5
0.5
0.4
1.76

YDR513W
2.2
2.5
2.3
2.6
0.9
2.1
1.6
1.6
4.6
3.1
2.0
0.9
1.8
2.0
1.3
3.8
1.3
3.2
3.10

YGR088W
1.3
1.2
7.7
2.4
1.0
1.3
0.8
0.8
1.5
3.2
3.9
1.1
1.2
1.3
0.7
5.6
0.9
2.0
0.75

YHR104W
1.0
4.1
15.7
1.9
1.1
1.2
1.5
1.1
4.8
2.3
2.6
1.0
1.2
1.5
1.6
1.3
1.9
1.9
1.57

YKL161C
4.2
0.8
0.9
2.2
1.4
2.0
2.0
1.9
1.4
1.7
3.1
0.9
1.3
1.4
1.3
1.1
1.4
1.9
0.45

YPL223C
4.8
20.0
1.2
5.1
0.9
1.5
1.1
1.2
29.4
16.5
1.8
0.9
2.3
2.5
1.5
19.0
1.0
1.3
0.31

YBR054W
1.9
1.8
5.4
1.7
0.8
1.1
0.6
2.1
0.4
1.2
1.8
0.7
1.5
1.0
0.6
0.4
0.7
0.7
3.02

YAL015C
1.2
1.1
1.7
1.9
1.1
0.7
1.2
1.1
4.0
2.7
1.4
1.0
1.2
1.6
0.7
2.0
1.1
1.2
0.61

YDL025C
1.7
5.0
3.5
1.5
0.6
0.6
1.0
1.1
3.6
4.5
1.5
0.9
1.2
1.7
1.0
1.7
1.0
1.4
0.56

YML007W
0.9
0.8
0.9
1.3
1.0
0.5
1.1
1.9
2.1
2.5
1.3
1.1
1.7
1.2
1.0
1.4
1.0
1.4
1.54

YER042W
3.0
2.2
3.1
1.0
1.1
1.6
1.1
1.7
6.8
2.1
1.8
1.1
1.4
5.2
1.0
1.9
0.7
1.1
1.80

YOL064C
1.4
2.1
1.1
0.6
0.9
1.4
1.2
1.0
8.7
2.7
1.0
0.9
2.0
0.9
1.0
1.7
1.2
1.3
1.32

YGL181W
0.9
0.9
1.2
1.1
1.1
1.9
1.3
1.2
2.7
2.3
1.2
1.0
2.8
1.0
1.5
1.3
1.0
1.3
0.98

YJL128C
0.8
1.4
0.4
0.8
1.2
1.3
1.8
0.9
2.0
1.7
0.6
1.0
1.7
0.8
1.2
0.9
1.0
1.0
0.42

YJL165C
1.0
0.8
1.3
1.6
1.1
0.5
0.8
0.7
2.8
1.0
1.7
0.9
1.5
0.9
1.0
1.5
1.3
1.8
0.87

YJR090C
0.8
1.0
0.6
0.8
1.2
1.2
0.8
0.8
1.9
1.2
0.4
0.8
2.2
1.0
1.6
0.8
1.1
1.0
0.60

YMR186W
0.6
1.4
2.0
0.9
1.3
1.3
1.2
0.8
2.6
1.3
1.1
1.0
2.4
0.6
1.3
0.6
0.7
1.1
6.64

YNL064C
0.9
1.8
1.8
1.1
0.9
0.8
0.6
1.4
2.4
1.8
0.9
0.8
1.1
0.8
0.7
0.3
0.7
0.7
3.79

YOR008C
0.7
0.8
1.4
1.1
1.4
1.1
0.8
0.8
1.9
1.0
1.0
0.7
0.9
0.9
0.9
1.2
0.8
1.3
1.75

YPL194W
0.9
1.4
0.4
1.1
1.3
1.1
1.5
1.3
9.6
3.1
0.9
0.9
1.4
1.1
1.4
0.9
1.0
0.8
0.22

YBL093C
1.0
2.0
0.4
1.4
1.0
0.8
1.3
1.6
0.7
1.1
1.3
1.1
2.1
1.0
0.5
0.9
1.4
1.3
1.47

YKR053C
0.9
2.0
1.0
1.2
1.0
1.1
1.7
0.9
0.8
1.8
0.5
0.7
0.7
1.3
0.3
0.9
2.8
2.4
0.35

YJL158C
0.9
0.6
2.8
1.5
1.4
0.5
0.4
0.7
0.2
0.5
1.9
1.1
0.4
0.5
1.7
0.6
1.4
1.4
3.48

YER057C
1.2
2.0
3.0
1.8
0.8
1.6
1.4
1.0
0.6
1.4
1.8
1.5
1.0
1.4
1.7
2.8
1.1
1.8
2.03

YHL046C
1.1
1.7
2.1
1.3
0.9
0.8
1.3
1.0
1.0
2.1
0.4
1.1
1.4
1.4
1.0
1.4
0.9
0.9
0.55

YIL011W
0.7
0.5
3.9
0.6
1.1
0.7
0.6
0.7
0.0
0.5
2.5
0.6
0.5
0.5
0.9
1.0
0.8
0.8
0.57

YKL164C
0.6
1.1
2.5
0.9
1.1
1.4
0.8
0.8
0.4
0.7
1.0
0.8
0.9
0.3
1.2
1.1
0.8
0.8
2.75

YNR076W
1.3
1.3
2.5
1.0
1.2
1.2
1.2
1.0
1.3
2.5
1.4
0.7
0.9
0.8
1.1
0.8
1.5
0.8
0.42

YOL161C
1.2
1.1
2.4
1.4
0.9
1.0
0.9
0.8
0.7
2.0
1.5
1.3
1.2
0.9
1.1
1.6
1.1
1.0
0.89

YOR009W
0.9
0.8
3.2
0.7
0.8
0.9
0.6
0.7
0.4
0.5
1.4
0.4
0.4
0.7
0.6
0.8
0.9
0.8
0.36

YOR010C
0.7
0.7
3.2
0.6
1.2
0.5
0.4
0.5
0.6
0.7
1.2
0.5
0.5
0.4
0.6
1.1
1.4
0.6
0.61

YPL059W
1.2
0.9
2.6
1.3
1.2
1.3
0.7
1.4
2.0
1.3
1.6
0.8
0.7
1.3
1.0
2.1
1.8
1.3
1.35

YBR044C
0.8
1.4
0.7
1.9
1.4
1.0
1.5
1.1
0.8
1.2
1.1
0.8
1.2
0.9
0.9
1.4
0.9
1.3
0.57

YEL039C
1.1
0.7
1.3
5.1
0.9
1.5
0.6
1.1
1.2
1.2
1.7
0.6
0.5
1.4
0.4
3.5
0.7
1.1
1.59

YGL115W
0.9
0.6
1.2
2.0
1.2
1.2
1.4
1.0
1.2
1.2
1.0
0.9
0.7
1.2
0.7
1.7
0.8
1.2
2.46

YLR006C
0.7
0.7
0.9
6.2
1.6
0.9
1.1
0.9
1.1
1.1
1.5
0.7
0.8
1.0
0.9
0.8
1.6
1.0
0.40

YPR005C
1.3
0.8
1.5
3.8
1.0
0.8
1.2
1.2
2.8
2.0
0.4
0.6
0.7
1.3
2.7
0.8
1.0
1.1
0.24

YHL028W
0.7
0.8
1.4
0.5
1.1
1.8
2.1
0.4
0.2
0.4
0.7
1.5
2.1
1.3
0.6
2.6
1.6
2.5
0.62

YCR083W
1.1
2.8
1.5
1.8
1.6
2.4
1.8
1.5
1.8
1.8
1.8
1.1
1.8
2.4
1.0
3.1
1.3
1.3
0.98

YPL140C
0.9
1.3
0.9
1.0
0.8
0.3
1.4
1.1
0.9
0.9
0.8
0.8
0.9
1.1
0.7
1.8
0.9
1.4
0.46

TABLE 7

Metabolism protein genes

The level of expressed mRNA in the presence of chemical substance/The level of expressed mRNA in the absence of chemical substance

In-

yeast genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
tensity

YCR107W
12.0
2.6
1.8
1.6
0.7
1.5
1.5
15.6
196.6
34.0
23.0
0.9
4.0
8.3
4.8
3.1
1.3
1.1
0.59

YDL243C
14.4
2.7
2.4
1.0
1.1
2.2
1.6
11.8
64.2
29.6
19.6
1.1
4.1
12.0
4.2
3.0
1.8
1.5
0.76

YFL014W
3.4
7.2
5.7
11.0
1.0
9.3
5.5
3.4
13.1
5.8
5.0
4.3
15.2
7.3
6.3
14.2
1.5
8.8
2.14

YFL056C
19.0
2.3
2.3
1.5
0.9
0.6
1.4
18.5
162.3
31.3
68.3
1.0
4.7
7.8
5.0
3.4
1.0
1.1
0.55

YFL057C
20.9
5.8
1.5
1.8
0.9
1.2
1.8
18.0
51.8
46.1
27.7
1.0
4.1
23.4
3.1
3.9
1.6
1.3
0.71

YJR155W
10.6
3.7
1.4
2.5
0.7
1.4
1.7
10.6
38.2
18.8
15.4
1.0
5.7
9.4
2.6
5.6
1.3
1.4
0.64

YNL331C
8.6
3.6
1.3
1.0
1.6
1.8
1.9
13.1
42.6
36.3
21.8
0.9
3.1
7.5
2.3
4.0
1.7
1.3
0.58

YNL332W
1.1
1.5
1.1
2.0
1.6
1.1
2.1
1.5
3.3
2.1
2.6
1.2
2.1
3.0
5.4
2.2
1.0
1.0
0.24

YOL165C
10.1
4.5
1.8
0.9
0.9
1.7
1.4
17.8
46.9
23.3
17.6
0.8
3.7
9.1
3.0
1.8
1.6
1.0
0.69

YPR167C
5.3
5.8
1.9
0.8
1.4
2.6
1.2
5.5
76.6
9.0
1.9
1.3
1.9
4.2
0.9
0.9
1.7
1.4
0.54

YBR256C
3.0
1.4
0.6
1.3
1.6
2.0
2.1
2.3
18.1
6.8
3.2
1.7
3.5
5.6
1.6
3.0
2.6
3.3
1.97

YBR296C
7.0
11.2
2.2
2.5
1.4
1.4
0.2
1.1
0.4
1.8
1.5
1.6
2.0
2.3
1.7
0.3
3.8
4.0
0.54

YDL021W
4.8
1.7
2.4
3.7
1.7
6.5
5.9
2.7
2.5
7.4
4.7
2.4
5.3
3.7
0.7
7.3
1.9
3.2
0.47

YFL061W
1.5
1.4
2.1
3.0
1.0
0.5
1.2
1.2
3.2
9.9
1.1
0.9
1.2
6.0
2.1
1.0
1.2
0.9
0.31

YGR043C
2.5
4.7
3.2
7.9
0.9
16.3
6.5
2.6
10.9
8.4
3.6
3.3
6.9
4.1
3.0
13.7
1.6
4.8
0.66

YHR112C
1.8
3.1
0.7
1.4
1.3
2.9
3.4
1.7
10.5
4.4
1.5
1.9
3.9
2.4
2.0
2.7
1.6
1.8
0.55

YIR030C
1.4
1.0
0.9
1.3
0.9
0.5
1.2
1.4
5.4
2.1
1.4
0.9
1.3
2.9
0.7
0.8
0.9
1.0
0.42

YJR010W
9.1
7.3
4.9
0.8
1.1
2.5
1.4
3.1
30.0
11.1
2.9
1.4
3.2
5.4
1.7
1.7
1.2
1.0
0.56

YKL001C
6.8
21.4
5.6
1.8
0.8
0.9
1.1
3.4
10.3
3.4
2.6
2.1
1.6
6.2
1.1
1.8
2.7
1.7
0.91

YKR097W
1.3
2.4
1.3
3.3
1.1
1.7
3.7
2.5
1.9
3.3
0.8
1.8
17.5
2.1
2.5
2.2
1.1
1.5
0.16

YLR303W
7.3
9.8
12.1
1.1
1.1
3.0
3.6
5.3
18.6
5.6
9.8
4.3
9.9
3.8
5.8
3.4
1.5
1.4
1.42

YNL274C
1.4
18.7
2.6
1.9
0.7
4.2
2.0
2.3
6.3
5.3
4.0
1.1
2.3
3.3
2.5
6.4
1.4
2.6
0.85

YOL151W
6.7
3.8
9.1
1.3
1.3
8.4
4.4
6.7
22.8
17.0
9.0
4.6
16.9
4.0
2.8
3.7
4.0
5.6
1.12

YOR226C
1.3
2.2
1.7
1.1
1.3
1.2
1.2
1.2
1.3
5.9
1.5
0.6
0.9
2.7
1.0
0.7
1.0
0.7
0.58

YJL153C
1.3
1.7
1.7
17.6
0.7
0.8
2.3
1.3
3.9
2.5
0.7
10.2
38.0
1.4
37.0
1.0
6.5
1.8
0.27

YOR153W
1.6
0.9
5.1
1.1
1.0
7.4
2.6
0.5
3.2
1.2
1.0
4.0
11.8
0.3
3.6
1.6
2.5
3.1
1.91

YPL088W
3.3
1.3
0.6
2.5
1.5
7.1
3.7
1.9
0.6
2.8
1.1
3.6
4.8
1.6
3.2
4.3
9.1
8.3
0.69

YDL124W
2.1
8.5
5.7
1.7
0.7
3.4
2.9
2.1
3.3
5.3
3.4
2.4
6.0
1.6
3.4
3.6
2.2
2.6
2.43

YDL174C
0.9
1.8
0.9
1.3
0.5
1.7
3.6
0.8
0.5
1.7
0.9
2.8
5.9
1.1
0.6
5.1
2.2
4.0
0.63

YGL156W
1.3
2.5
1.8
2.2
1.4
2.1
2.1
1.4
5.6
2.4
2.1
2.6
6.0
1.6
3.0
4.1
1.4
1.9
0.29

YGR157W
1.0
0.9
5.2
0.8
1.2
1.0
0.8
0.7
3.3
2.0
1.0
1.8
4.8
0.7
4.6
1.0
0.8
1.3
2.10

YHR043C
1.3
1.8
1.2
1.7
0.9
2.2
2.9
3.0
1.2
1.0
1.6
2.2
2.7
1.3
2.1
2.2
1.4
1.7
1.38

YHR044C
1.3
1.3
1.7
1.5
1.2
3.3
2.6
2.0
1.1
1.1
1.7
2.3
4.3
1.3
1.5
2.4
1.3
1.4
1.12

YJR073C
1.1
2.4
2.7
2.7
0.6
2.2
2.9
1.0
6.8
2.8
2.8
4.1
10.0
2.3
28.9
3.7
2.9
2.6
0.99

YOR303W
1.1
2.2
0.5
1.0
1.2
1.8
1.2
1.6
0.9
5.2
0.9
1.9
3.3
1.6
4.1
1.2
1.2
0.8
1.47

YBR294W
6.3
12.0
0.9
2.6
1.4
1.2
1.1
1.0
5.2
5.2
1.2
1.0
3.1
1.3
1.0
0.9
1.0
0.9
0.18

YCL043C
0.6
3.7
2.5
0.7
0.9
1.3
1.0
0.8
1.6
1.2
1.7
1.5
4.1
0.6
5.7
0.8
0.9
1.0
2.37

YCL050C
1.0
1.1
1.9
0.7
1.4
1.2
1.2
1.2
3.0
2.9
1.3
1.2
2.8
1.2
0.8
0.7
1.0
1.0
2.20

YCR012W
1.1
1.5
5.1
1.2
1.1
2.5
1.4
0.8
1.4
1.5
1.8
1.2
4.1
0.9
1.4
1.4
0.8
1.3
4.48

YDR158W
1.1
0.5
1.8
0.8
1.3
1.0
0.8
1.2
1.1
1.7
1.6
1.0
2.6
0.9
1.0
0.6
1.0
0.9
3.54

YDR204W
0.9
2.3
3.0
1.4
1.0
2.2
2.2
1.1
5.7
3.7
2.2
1.2
2.9
1.1
0.6
2.8
1.1
1.7
0.62

YDR313C
1.2
1.2
1.2
1.4
1.3
1.4
1.5
1.2
4.7
2.6
1.5
1.2
2.3
1.3
0.8
2.9
1.1
1.3
0.84

YDR368W
2.0
2.2
2.2
1.8
1.0
3.0
2.1
1.7
3.8
3.8
1.8
1.4
2.6
2.0
1.2
2.3
1.1
2.0
1.70

YER091C
3.6
3.9
30.7
1.3
0.9
2.3
2.1
0.9
5.8
1.4
3.2
2.0
5.4
1.2
10.2
2.7
1.2
1.0
1.23

YFR053C
1.7
1.4
3.0
2.2
0.9
3.2
2.1
2.8
0.6
1.1
1.5
1.7
3.0
0.6
0.6
3.0
1.4
2.2
4.17

YGL062W
0.6
1.3
1.1
0.6
0.9
1.0
1.3
0.8
1.6
2.5
0.7
1.6
4.5
1.2
2.7
1.5
1.1
0.9
0.77

YGL157W
0.7
0.9
1.8
0.9
1.5
5.4
3.3
1.4
0.6
1.8
1.4
1.5
4.8
1.2
5.1
1.7
1.8
2.3
1.69

YGL184C
4.6
15.9
57.4
1.3
1.1
1.0
1.2
1.9
37.9
66.8
1.7
2.6
7.4
1.4
0.4
1.5
1.0
0.9
0.16

YGR032W
1.0
1.4
1.0
1.3
0.7
1.9
0.8
0.6
0.5
0.7
1.5
1.5
3.9
1.1
5.4
1.5
3.2
2.8
1.18

YGR124W
0.5
0.6
1.7
0.7
1.2
1.1
0.7
1.0
2.2
1.3
1.1
1.1
2.3
0.5
1.5
0.3
0.7
0.6
3.56

YGR192C
1.4
1.0
3.8
1.0
1.1
1.7
1.7
1.1
0.9
1.3
2.3
2.2
3.4
1.0
1.9
1.1
1.1
1.3
7.49

YGR244C
1.0
1.2
1.6
1.6
0.8
2.6
3.9
1.8
1.4
1.1
1.8
1.9
2.6
1.2
2.0
2.6
1.9
3.1
1.12

YGR254W
1.2
1.3
3.8
1.3
1.2
1.9
1.5
1.4
0.8
1.2
1.3
1.7
3.1
0.6
2.4
1.4
1.3
1.2
7.01

YHR018C
1.0
1.0
1.5
1.4
1.7
1.1
0.8
1.0
1.4
4.4
1.4
1.4
3.3
1.0
4.4
1.0
1.9
1.2
1.21

YIL160C
0.8
2.4
2.3
3.5
1.0
1.6
1.1
1.2
3.2
3.8
2.4
1.0
2.3
1.5
5.6
8.8
2.4
3.0
0.27

YIR017C
3.5
8.6
2.5
1.9
0.8
1.9
1.5
1.2
5.2
3.4
4.2
1.2
3.4
1.9
2.3
3.0
1.5
1.3
0.36

YJL052W
1.5
0.9
4.0
1.8
0.7
2.4
2.1
1.5
1.6
2.0
4.3
2.4
5.6
1.3
2.3
2.3
1.2
1.9
6.19

YJR009C
1.1
1.7
5.6
1.0
1.2
1.6
1.6
1.1
1.1
1.3
1.1
1.5
2.7
1.0
2.1
1.5
1.1
1.3
5.86

YJR130C
1.1
0.6
0.8
0.9
1.4
2.0
1.3
1.3
5.2
3.8
1.7
1.0
2.9
1.1
0.9
1.5
1.1
1.3
0.62

YJR149W
1.0
1.8
1.4
2.3
0.8
1.0
1.7
1.0
1.4
1.0
0.7
1.0
3.5
1.4
1.4
2.4
1.1
1.2
0.34

YKL218C
2.1
1.0
2.2
1.8
1.2
3.6
1.6
1.7
3.4
2.7
1.7
1.2
5.1
1.4
0.8
3.1
2.5
2.6
0.60

YLR027C
1.0
1.5
2.3
0.8
0.9
2.0
1.4
0.7
1.6
2.7
1.6
1.3
2.5
1.0
1.4
0.9
1.3
1.3
1.39

YLR133W
0.9
1.6
1.4
0.7
1.0
2.2
1.3
0.7
6.1
2.3
0.6
1.5
3.3
1.1
1.9
1.0
1.1
1.3
0.36

YLR155C
1.4
1.1
2.4
1.8
1.7
1.6
2.0
1.0
3.0
1.8
2.0
1.1
3.3
1.1
1.2
2.2
1.4
2.2
1.63

YLR158C
1.4
1.2
2.1
1.7
1.7
1.5
2.0
1.1
2.7
s
2.4
1.1
3.2
1.2
1.1
2.1
1.4
2.0
1.57

YLR195C
0.8
0.9
1.0
0.8
1.0
0.8
1.1
1.0
0.6
0.7
0.8
1.3
2.3
0.7
0.9
0.8
0.9
1.0
1.55

YLR345W
1.4
1.4
1.4
1.2
1.2
1.6
1.2
1.4
4.5
4.0
2.5
1.6
3.5
1.5
1.0
1.2
1.2
1.4
2.65

YML004C
0.8
1.6
2.5
1.0
0.7
1.7
2.1
1.9
3.9
2.2
2.2
1.1
2.4
1.4
2.1
4.5
1.5
2.4
2.41

YML131W
11.2
4.3
7.7
1.9
0.7
2.0
3.0
6.1
11.1
17.7
14.4
1.1
2.4
2.7
2.2
1.6
2.5
3.0
1.15

YNL071W
0.9
0.9
1.7
1.5
0.6
1.3
1.4
0.9
1.1
1.2
1.6
1.3
2.5
0.8
1.1
1.1
1.0
1.2
1.61

YNL241C
1.3
2.5
4.3
1.0
0.8
0.9
3.2
0.9
3.4
7.4
3.0
2.0
4.9
1.1
7.0
2.8
1.0
1.0
0.68

YOR120W
1.8
5.4
2.8
3.2
1.4
3.4
2.7
2.0
3.3
3.0
3.0
1.2
3.6
2.4
1.5
3.9
1.3
2.6
1.06

YAL023C
0.4
1.5
1.0
0.7
1.0
0.6
0.8
0.6
0.3
0.4
1.7
1.2
2.3
0.4
2.5
0.4
1.0
0.7
1.49

YAL060W
1.1
1.8
3.2
2.7
1.2
4.2
3.3
0.9
0.6
2.5
2.4
0.8
2.2
0.9
0.9
3.2
1.1
1.8
2.39

YAL062W
0.8
1.5
1.4
1.1
1.0
1.2
1.1
0.8
1.4
0.7
1.2
1.0
2.1
0.8
1.1
1.3
1.0
0.8
0.86

YBR006W
1.3
1.6
2.6
1.5
1.3
3.1
3.3
1.0
4.5
2.7
1.9
1.1
2.2
1.1
1.1
3.0
1.2
1.8
0.62

YBR056W
1.4
1.7
1.4
2.3
1.4
2.3
5.5
1.4
3.0
3.3
1.8
1.4
3.0
1.0
0.7
2.8
2.4
3.4
1.13

YBR149W
1.1
2.0
2.7
1.7
1.4
2.8
3.1
1.5
1.7
1.9
1.9
1.4
2.2
1.2
0.7
2.7
2.1
3.4
2.72

YBR284W
0.9
1.5
2.8
4.8
1.3
1.9
1.0
0.9
6.5
3.2
1.4
1.2
2.8
1.6
0.8
0.8
1.1
1.0
0.25

YCL018W
1.2
2.7
2.4
1.4
0.8
2.3
2.3
1.3
2.1
4.3
3.7
1.6
3.2
1.0
0.6
2.3
1.3
1.0
0.99

YCL040W
0.9
7.1
10.1
2.0
0.5
3.5
2.9
0.7
0.9
3.0
8.2
2.3
5.6
0.7
3.4
3.1
1.4
1.7
1.98

YDL010W
1.7
0.8
0.6
0.7
1.2
1.1
1.9
1.1
2.2
1.3
1.3
0.9
2.0
2.2
1.4
1.4
1.5
2.4
0.93

YDL024C
1.6
1.5
1.2
2.2
1.0
1.7
0.9
1.7
4.2
3.4
1.2
1.7
2.6
1.9
2.1
2.8
0.9
1.1
0.40

YDL095W
0.5
1.3
1.0
0.8
0.8
1.0
0.8
0.7
1.2
0.7
1.0
1.1
2.2
0.5
2.0
0.5
0.7
0.9
1.57

YDL245C
1.0
2.4
1.6
2.2
1.3
1.1
1.2
1.2
0.4
2.8
1.5
1.0
2.0
1.2
1.8
1.5
1.0
1.1
0.28

YDL246C
1.2
1.5
1.3
1.1
1.1
1.4
2.1
2.4
4.4
3.6
2.6
1.2
2.9
1.7
2.6
1.7
1.8
1.8
0.43

YDR001C
0.8
2.2
2.6
1.0
1.1
2.2
1.5
0.9
2.2
3.0
0.7
1.1
2.8
1.0
4.4
1.9
1.1
1.6
0.75

YDR058C
1.2
2.2
0.8
2.7
0.7
1.0
1.4
1.9
2.4
1.7
1.7
1.2
2.5
1.8
1.2
1.9
1.1
1.6
0.56

YDR072C
1.3
1.3
1.7
1.2
0.9
1.5
0.9
0.7
0.6
0.7
0.7
0.9
1.9
0.6
0.4
0.7
1.9
1.9
2.81

YDR127W
0.8
0.9
1.5
0.7
1.2
0.8
0.9
0.7
0.6
1.3
1.3
0.8
1.7
1.0
1.3
0.6
0.9
0.7
0.78

YDR261C
1.2
1.2
1.9
0.7
1.3
1.4
0.8
0.9
1.7
1.0
1.2
1.0
1.9
0.9
2.3
0.6
0.9
0.8
0.68

YDR272W
1.0
4.0
0.8
1.8
0.7
2.3
1.7
2.1
2.5
1.9
2.1
1.2
2.4
1.4
1.1
2.1
1.4
2.3
1.51

YDR497C
0.7
0.5
0.6
1.3
0.7
0.6
0.5
0.6
0.4
0.8
0.7
0.9
2.7
0.6
10.1

1.6
1.8
1.45

YDR516C
1.2
1.5
7.8
2.1
1.3
1.8
3.9
1.3
1.8
5.2
2.8
1.1
2.5
0.7
0.4
1.7
1.1
1.2
1.66

YER053C
1.6
1.8
1.9
1.7
0.6
2.8
2.8
1.3
1.3
3.9
2.4
1.7
4.1
1.3
1.1
2.8
1.2
2.3
1.83

YER096W
1.1
2.3
2.0
2.0
1.3
1.2
0.9
1.0
7.5
3.5
1.1
0.9
2.3
3.1
1.4
2.0
1.0
1.2
0.22

YER178W
0.8
0.9
3.6
1.0
0.7
2.5
1.6
0.8
1.7
1.3
2.5
1.3
2.4
0.9
1.8
1.0
1.1
0.9
2.18

YFL030W
1.6
6.0
3.1
2.0
1.1
1.3
0.6
1.6
24.5
4.9
5.4
1.2
2.2
0.8
1.1
0.6
1.0
0.8
0.50

YFL031W
0.5
1.3
2.1
0.7
1.0
0.3
0.9
0.7
1.0
0.7
1.2
1.0
2.6
0.4
2.7
0.9
1.2
1.1
3.16

YFR047C
1.3
4.0
2.7
2.6
1.2
2.0
2.0
1.0
3.0
1.5
2.3
1.7
2.7
1.9
0.6
3.6
1.5
1.6
1.57

YGL248W
1.3
1.3
0.9
0.7
1.3
2.7
1.6
0.8
0.2
2.9
1.0
0.8
2.0
1.3
1.8
2.9
1.1
1.2
0.22

YGR037C
1.0
1.2
2.2
0.8
1.0
1.1
1.4
1.4
1.7
1.4
1.4
1.5
2.7
1.5
1.5
2.6
1.4
2.0
3.40

YGR055W
2.5
5.7
12.0
0.7
1.3
1.1
0.6
1.1
5.0
2.4
1.5
0.9
1.9
1.2
2.1
0.6
0.7
0.7
1.42

YGR194C
0.9
1.0
1.3
2.1
0.8
1.9
2.2
1.2
2.4
2.1
0.7
0.8
2.2
1.0
0.6
2.6
1.1
2.0
0.63

YGR256W
1.2
1.5
2.3
0.8
0.9
6.2
1.4
2.2
3.4
2.5
2.7
1.5
3.9
1.1
2.7
5.3
1.1
0.8
0.94

YHR111W
1.4
1.3
0.8
1.9
1.5
1.3
1.6
1.3
4.5
4.2
1.9
0.9
2.2
1.7
1.1
1.3
1.1
1.2
0.44

YHR174W
1.1
1.4
3.3
1.2
1.3
1.5
1.6
1.2
1.0
1.5
1.4
1.5
3.6
0.6
2.0
1.1
1.0
1.2
7.34

YHR176W
1.8
2.0
1.1
1.4
1.0
2.3
1.4
1.3
6.3
6.4
1.2
1.2
1.9
1.3
1.5
1.8
1.4
1.6
0.27

YIL045W
1.7
1.4
1.9
2.2
1.3
1.7
1.6
1.1
2.1
3.2
1.2
1.5
2.0
1.6
0.6
2.9
1.1
1.8
0.37

YIL107C
1.5
0.8
1.1
1.5
0.8
1.0
1.6
1.3
3.5
3.5
0.9
1.1
1.9
1.6
1.0
2.7
1.2
2.0
0.58

YIL155C
1.0
0.7
1.4
3.7
1.3
1.4
2.2
1.0
2.5
2.9
1.3
1.4
2.0
1.3
1.4
3.8
1.1
1.4
0.51

YIR034C
1.2
1.1
2.5
0.6
1.1
1.3
0.8
1.7
3.2
3.5
3.0
1.4
2.6
1.2
1.9
1.3
1.0
1.0
0.92

YIR036C
1.0
1.7
2.6
1.8
0.9
0.7
1.0
1.0
3.3
1.9
2.8
1.2
1.9
1.2
1.1
4.0
1.5
1.3
0.64

YJL031C
1.6
1.2
0.5
1.3
1.7
1.6
2.3
1.8
4.7
3.6
1.9
1.3
2.6
3.0
2.0
1.9
1.2
1.9
1.02

YJL068C
1.2
2.7
3.4
1.6
0.7
1.1
1.2
1.1
6.5
3.1
3.2
1.7
2.7
1.5
0.5
2.6
1.4
1.5
0.95

YJL099W
1.2
1.2
0.3
1.3
1.9
2.0
1.8
1.0
3.1
3.1
0.9
1.0
2.4
1.8
1.4
1.7
1.2
1.6
0.55

YJL172W
0.8
2.1
1.8
1.5
0.9
3.8
1.0
0.7
0.7
1.9
1.4
1.1
3.1
0.9
1.2
0.5
1.8
1.8
0.62

YJL219W
1.2
2.5
3.1
1.6
1.2
1.5
0.9
1.5
4.0
2.3
2.3
1.1
4.0
1.1
2.6
1.4
1.6
1.2
0.91

YJR137C
2.7
2.9
4.6
0.8
0.6
1.5
0.8
1.6
9.0
4.8
2.0
1.4
2.1
1.2
1.0
1.3
0.9
0.8
0.46

YKL035W
1.0
0.9
4.8
1.2
0.8
1.2
0.6
1.0
0.8
1.2
2.1
1.0
2.0
0.6
1.0
1.5
1.0
1.9
2.54

YKL091C
1.2
1.3
1.4
2.6
1.0
2.2
1.9
1.3
2.3
3.2
1.7
1.3
2.0
1.5
1.1
4.6
1.4
2.0
0.83

YKL104C
1.0
1.0
1.6
1.2
1.4
0.9
2.3
1.1
1.4
1.8
2.2
1.6
2.2
0.8
3.3
0.6
1.0
1.1
1.25

YKL152C
1.3
1.3
1.9
0.9
1.3
1.6
1.5
1.0
0.9
1.5
1.7
1.5
2.7
1.0
1.8
2.0
1.1
1.7
3.28

YKL213C
0.9
0.8
1.0
1.3
0.7
1.0
1.0
1.1
4.8
2.1
1.3
0.9
2.1
0.9
1.1
1.5
1.4
1.6
0.77

YKL215C
0.6
1.1
1.3
0.8
1.0
2.1
1.1
1.1
1.3
1.9
0.5
1.0
2.6
1.0
0.9
0.8
0.8
0.9
0.38

YLL058W
1.0
3.8
1.4
0.9
0.8
1.4
1.5
0.9
3.5
3.6
2.0
1.0
2.3
0.8
1.9
1.1
1.4
1.3
0.39

YLR299W
1.2
1.9
1.5
1.3
0.6
0.9
0.8
1.0
4.9
2.3
1.7
1.0
2.9
1.3
1.5
0.9
1.3
1.4
0.57

YLR348C
1.1
4.5
1.2
1.2
0.9
1.9
0.9
0.9
2.1
1.3
1.3
0.9
1.9
1.0
2.4
1.1
1.1
1.0
0.64

YML054C
1.5
1.8
1.3
3.4
1.3
1.8
1.2
1.5
4.1
1.8
1.4
1.8
2.8
2.1
1.1
7.8
1.1
1.6
0.25

YML070W
0.9
1.7
2.5
1.9
1.4
2.2
3.1
1.3
4.5
3.9
1.5
1.3
3.3
1.3
0.9
2.6
1.2
1.3
1.03

YML100W
0.8
2.7
10.6
1.4
0.9
2.8
2.2
0.7
1.7
1.4
3.2
1.2
3.8
1.2
1.8
2.2
1.0
1.5
0.88

YMR008C
0.7
0.9
1.4
1.0
1.1
1.7
0.9
0.5
0.3
0.6
1.3
1.1
3.7
0.7
2.0
1.2
3.0
1.9
1.59

YMR020W
1.3
1.0
0.9
1.7
1.4
1.6
2.7
1.2
2.3
2.9
1.5
1.1
3.0
1.1
1.8
2.8
2.3
2.2
0.81

YMR105C
1.9
3.0
5.0
4.2
0.9
2.8
2.8
1.1
0.6
2.9
3.0
1.7
3.3
1.0
0.9
2.0
1.6
2.6
1.21

YMR271C
1.6
1.6
1.3
2.0
1.1
4.2
3.4
1.8
8.0
4.4
1.7
1.3
3.6
1.8
0.6
5.7
1.3
2.2
0.70

YNL012W
1.3
1.3
1.8
0.8
1.3
1.7
2.0
1.8
3.3
3.2
1.6
1.3
2.9
1.0
1.6
1.2
1.3
1.5
0.24

YNL045W
0.8
1.3
2.0
1.3
1.1
2.2
1.8
0.7
1.3
1.1
2.1
0.9
2.6
0.8
0.8
2.4
1.1
1.1
0.80

YNL104C
1.1
1.3
3.0
0.9
0.8
0.8
0.6
0.9
1.1
2.0
2.1
1.1
2.1
0.9
2.5
1.5
0.9
0.9
1.69

YNL231C
1.5
0.8
0.8
0.5
2.1
1.8
2.5
1.5
2.2
1.3
1.3
1.8
2.9
0.9
0.9
0.7
3.1
4.0
2.13

YNR019W
1.0
1.3
1.6
1.2
0.8
1.3
0.8
0.7
1.8
1.9
0.7
1.0
2.1
1.0
1.6
0.8
2.4
2.0
0.37

YNR033W
0.6
0.8
0.8
1.0
1.3
1.6
1.2
1.1
3.6
4.2
0.4
1.1
3.8
0.9
1.3
2.2
0.9
1.1
0.72

YNR059W
1.1
0.9
0.2
1.4
1.4
0.8
1.6
1.3
1.8
1.4
1.0
0.8
2.4
1.0
1.0
2.0
2.6
2.2
0.45

YOL126C
1.0
0.8
1.0
1.6
0.7
1.5
1.4
0.9
0.8
2.4
1.8
1.1
2.6
1.2
1.4
2.5
1.6
2.4
0.59

YOL153C
1.0
1.2
2.1
3.9
1.2
1.9
3.3
1.0
2.5
3.2
2.4
1.9
2.9
1.5
1.2
5.4
1.1
1.7
0.37

YOR099W
0.8
1.3
2.1
1.3
1.5
0.9
1.0
0.9
0.6
0.7
1.2
1.1
1.6
0.7
1.5
1.1
1.2
2.3
3.94

YOR130C
0.8
1.7
1.4
1.0
1.8
1.6
1.3
0.8
2.0
1.7
0.6
0.9
2.1
1.3
1.0
0.8
1.5
1.1
0.51

YOR336W
0.7
1.4
0.7
1.0
1.3
1.7
1.2
0.8
1.7
1.5
1.4
1.0
2.1
1.1
0.6
0.9
1.0
1.0
0.44

YOR347C
0.9
0.9
2.1
2.2
0.7
0.9
0.9
0.8
0.5
0.9
1.4
1.2
1.8
0.9
2.0
1.4
1.7
1.3
1.31

YPL017C
1.0
2.5
0.8
1.0
1.3
1.5
1.4
1.3
3.0
6.7
0.4
1.0
1.9
1.6
1.0
1.3
1.3
0.8
0.19

YPR026W
0.9
1.2
5.0
1.3
0.8

1.3
1.0
0.9
3.1
1.6
1.2
2.3
1.5
3.1
2.5
0.9
1.3
0.26

YAL012W
1.1
6.5
10.4
0.8
0.6
1.6
0.6
0.7
4.7
3.9
4.0
1.1
1.1
0.9
3.1
1.0
0.9
0.8
0.96

YBR029C
0.7
0.2
1.8
1.0
1.4
0.8
0.4
0.7
2.0
1.1
0.7
1.3
1.7
0.9
3.5
0.9
0.6
0.8
1.56

YBR222C
0.6
1.2
1.3
0.8
0.7
1.3
1.0
0.6
0.7
1.0
1.3
0.9
1.6
0.5
4.3
2.1
0.8
0.9
0.52

YCL009C
0.6
0.9
2.0
0.5
0.7
1.8
1.3
1.1
0.9
1.6
1.5
1.7
1.6
0.7
6.5
0.9
1.1
0.8
0.68

YCL064C
0.6
0.6
0.8
0.8
1.4
3.3
13.4
2.4
1.7
5.2
1.8
0.7
1.6
0.8
21.4
1.0
0.3
0.3
1.42

YCR098C
1.6
3.0
1.7
2.0
1.4
1.6
1.2
1.0
1.4
2.4
1.3
1.3
1.4
1.1
11.0
0.8
1.7
1.6
0.22

YDR502C
1.2
2.8
2.4
1.2
1.5
1.5
0.9
0.9
1.6
0.9
1.3
1.3
1.2
0.8
8.2
1.0
0.9
0.9
2.75

YER026C
0.8
0.6
3.3
1.0
1.2
2.5
1.6
0.8
0.9
1.5
0.9
1.7
1.9
1.1
4.0
1.4
1.7
3.2
4.48

YHR137W
0.7
1.0
2.4
1.7
1.0
0.7
0.4
0.4
0.2
0.9
0.6
0.6
0.6
0.8
2.8
0.4
0.8
1.3
1.40

YMR189W
0.7
0.8
1.9
2.8
0.4
1.9
0.8
0.4
0.7
0.9
8.2
0.6
0.9
1.6
5.6
0.9
1.0
0.8
0.88

YNL106C
1.0
1.4
0.8
1.5
0.8
1.0
0.9
0.8
0.7
1.4
0.9
0.8
0.9
1.1
3.3
1.2
1.1
0.9
0.37

YNL169C
0.7
1.4
1.4
1.2
0.7
1.4
0.7
0.8
1.1
1.1
0.8
1.0
1.7
0.9
3.4
0.8
1.1
1.3
1.05

YNL322C
0.8
0.9
1.9
0.8
1.4
1.1
0.9
0.7
0.7
0.8
0.6
0.7
0.8
1.2
3.7
0.9
0.9
1.0
0.75

YAL038W
1.0
1.0
3.0
1.4
1.4
1.3
0.9
1.1
0.1
1.1
1.0
1.2
1.8
0.5
3.1
0.9
1.0
1.0
7.02

YBR023C
0.5
0.8
1.3
1.1
0.8
0.5
0.7
0.5
0.3
0.4
0.9
0.8
0.5
0.8
2.8
0.7
0.7
0.9
0.93

YCR048W
0.5
1.1
1.0
0.6
0.9
0.2
0.9
0.8
0.8
0.5
1.2
0.9
1.3
0.9
3.1
1.1
1.2
0.8
0.29

YDR380W
0.8
0.8
0.8
1.7
1.1
0.4
0.5
0.2
0.2
0.3
0.4
0.4
0.4
0.6
2.4
0.2
0.8
0.8
1.04

YER069W
1.3
0.8
3.3
1.4
1.5
1.3
1.0
1.5
0.8
10.4
1.5
0.8
1.4
1.3
2.4
1.1
1.1
0.9
0.25

YGL022W
0.5
0.8
1.4
0.3
1.0
0.9
0.7
0.4
0.9
0.4
0.8
0.7
1.0
0.5
4.0
0.3
0.9
0.7
0.91

YGL126W
0.6
1.3
1.4
0.8
1.1
1.6

0.7
1.6
0.7
1.0
0.6

2.8

0.9
0.9
0.34

YGL209W
1.2
1.6
1.1
2.6
0.7
1.0
1.0
1.1
0.6
0.4
0.8
1.3
1.9
1.6
3.2
2.8
1.1
1.5
0.63

YGR282C
1.3
0.7
4.6
1.9
1.0
2.2
1.1
1.0
0.8
0.8
1.5
1.3
1.2
1.0
2.9
1.4
1.1
1.5
5.04

YIL154C
0.8
1.3
1.9
0.8
0.9
1.1
1.3
0.6
2.4
1.0
1.2
1.1
1.7
0.9
4.3
1.2
1.2
1.0
0.39

YJL088W
0.9
0.8
2.2
0.5
0.9
2.8

1.3
3.2
4.1
0.9
0.7
1.0
2.0
5.7
0.7
1.4
0.9
0.27

YJR148W
0.7
1.4
2.0
3.5
0.6
2.0
2.1
0.6
0.7
3.0
0.6
0.8
1.1
1.3
3.2
1.3
1.3
1.7
1.50

YLR180W
1.3
1.4
2.4
1.0
0.8
1.2
0.6
0.9
0.8
0.9
1.7
0.6
0.6
0.6
2.5
0.5
0.8
0.7
3.23

YLR273C
1.4
1.0
1.3
2.4

1.2
1.2
1.3
2.8
2.4
1.4
0.9
1.7
1.3
2.6
1.5
1.0
1.0
0.20

YLR300W
0.9
0.8
0.8
1.0
0.8
1.1
0.5
0.8
0.0
0.5
1.0
0.5
0.2
0.6
2.7
0.3
0.7
0.5
5.14

YLR307W
0.9
0.4
0.7
3.3
1.4
1.2
1.5
1.2
0.6
0.7
0.8
0.7
1.0
1.9
3.9
0.9
1.1
1.0
0.16

YMR296C
0.6
0.7
1.2
2.6
0.4
0.4
0.6
0.5
0.4
0.6
0.8
0.8
0.9
0.7
6.7
0.5
0.8
0.7
0.52

YOL058W
0.8
0.5
1.7
0.9
1.2
0.8
0.4
1.6
0.1
15.7
2.3
1.3
1.2
1.5
2.7
0.9
1.2
0.8
0.82

YBR183W
1.8
1.5
2.0
2.9
0.9
2.5
1.7
1.0
0.4
2.0
1.9
1.2
1.4
1.3
1.1
2.1
1.4
2.4
1.47

YDR019C
1.4
0.5
1.7
4.0
0.9
4.8
1.4
0.7
0.4
0.7
1.8
0.7
1.0
1.6
1.8
1.8
1.2
1.6
2.48

YIL167W
3.3
1.6
2.0
1.0
1.0
7.7
1.2
1.9
6.9
12.7
1.9
0.7
1.2
1.4
0.6
2.3
0.7
0.8
2.11

YKR039W
1.4
3.5
1.3
1.7
1.0
2.8
1.0
1.0
1.9
2.0
1.9
1.5
1.3
1.2
1.7
1.9
0.9
1.1
0.40

YNL037C
1.4
1.8
1.7
1.1
1.7
2.8
2.8
1.0
0.6
3.2
1.4
1.3
1.9
1.3
0.9
1.4
0.9
1.3
2.05

YNR002C
1.3
1.6
1.0
2.0
1.2
2.3
1.2
1.0
3.9
1.6
1.6
1.2
2.1
1.2
1.0
2.4
1.5
2.1
0.29

YOL143C
1.0
1.4
1.2
1.2
0.9
3.5
1.3
1.2
0.8
1.0
2.0
1.2
1.2
0.7
1.0
2.2
1.8
1.4
2.30

YOR136W
1.0
0.9
3.5
1.0
1.5
3.9
3.2
1.1
0.3
3.4
1.4
1.2
1.5
0.9
1.2
1.3
0.8
1.3
3.20

YAL044C
1.5
1.1
1.0
3.0
0.8
2.2
1.0
0.8
0.4
0.6
1.4
0.6
1.1
1.4
0.7
1.0
1.4
1.8
4.07

YAL054C
1.2
1.1
1.4
1.6
1.1
2.2
1.1
1.1
8.9
4.1
1.3
1.0
1.8
1.3
0.9
2.5
1.5
1.4
0.24

YAR071W
1.6
0.8
1.0
0.7
1.6
2.0
0.3
1.4
0.3
0.3
1.1
2.0
0.3
1.1
1.1
0.3
0.7
1.6
3.21

YBL001C
1.1
1.5
1.0
1.6
1.0
2.4
1.3
1.0
1.5
0.9
2.3
0.7
1.0
1.5
1.0
1.7
1.6
1.8
2.38

YBR014C
1.1
1.2
0.8
0.9
1.4
2.0
1.4
1.2
1.3
0.8
1.8
0.6
0.9
1.2
1.2
1.5
1.0
1.6
1.29

YBR035C
1.1
1.0
1.7
1.1
1.3
2.3
1.5
1.5
2.2
1.5
2.0
1.2
1.8
1.3
0.7
2.1
1.5
1.9
1.89

YBR068C
1.1
1.0
1.9
2.5
1.4
1.9

1.0
0.8
2.5
0.8
0.8
2.2
1.8
1.6
5.5
1.1
1.3
1.99

YBR111C
1.0
0.9
1.0
1.7
1.3
3.0
2.2
1.7
1.9
1.9
1.5
1.2
1.6
1.6
0.7
3.5
1.4
2.4
3.20

YCR037C
0.7
1.0
0.8
0.8
1.3
1.8
1.0
0.7
0.6
0.6
0.8
0.7
1.3
0.8
1.0
1.1
1.4
0.9
0.74

YDL022W
0.9
2.6
6.9
1.5
0.7
2.1
1.5
0.8
1.2
1.8
2.8
1.2
1.5
0.8
0.9
1.1
1.0
1.4
1.79

YDR009W
1.4
0.8
1.5
1.0
1.2
2.4
1.4
1.2
1.3
2.0
0.1
1.0
1.2
1.5
3.2
1.0
1.2
1.0
0.21

YDR410C
0.8
2.0
1.3
0.9
1.1
2.5
1.4
0.9
1.2
1.5
1.6
0.9
1.2
1.3
1.2
0.8
1.0
1.0
1.33

YDR487C
2.2
0.9
1.3
1.1
1.3
2.3
1.3
1.8
2.7
2.3
2.1
1.3
1.5
2.5
1.0
1.5
1.5
1.9
2.61

YEL011W
2.0
1.6
1.7
6.3
1.1
2.8
2.7
0.9
2.5
1.6
3.7
1.5
1.5
1.5
0.4
2.4
1.4
2.5
0.89

YFR015C
1.2
0.8
3.2
2.1
1.2
3.0
7.3
0.7
0.3
1.8
3.9
0.4
2.5
3.1
0.4
2.4
1.3
1.2
0.66

YGL001C
1.0
1.0
1.4
1.1
1.5
2.8
1.4
1.1
0.8
0.8
1.6
0.9
1.0
1.1
0.9
2.2
1.9
2.1
2.53

YGL104C
0.8
2.0
2.1
1.8
1.0
2.1
1.2
0.8
4.6
2.1
1.8
1.1
2.0
1.0
0.9
1.7
1.3
1.3
0.58

YGL154C
1.3
1.4
1.5
0.9
1.0
1.7
0.7
1.2
2.0
1.4
0.9
0.9
2.0
1.1
0.8
0.7
1.0
1.1
0.57

YGL253W
0.8
1.0
3.2
0.7
1.3
2.4
1.7
1.1
0.3
1.4
1.0
1.2
1.5
0.5
0.8
0.4
0.7
0.8
4.63

YGR060W
0.7
0.6
0.9
0.7
1.9
2.5
0.5
1.0
0.5
0.4
0.8
1.0
0.6
0.8
1.4
2.1
1.3
1.6
4.19

YHR037W
0.7
0.9
1.3
1.6
0.9
1.8
1.2
1.0
0.9
2.2
1.7
1.1
1.1
1.1
1.1
2.0
1.0
1.4
1.15

YHR092C
2.3
1.0
7.5
2.5
1.4
1.7
0.5
1.5
0.2
0.9
1.5
1.0
0.5
1.6
0.2
1.2
0.9
1.3
6.09

YHR190W
0.8
3.9
1.2
1.2
1.8
1.7
1.9
1.2
2.4
1.9
1.3
1.1
1.7
1.3
1.3
1.8
1.3
1.8
2.15

YIL033C
0.8
1.3
3.3
1.3
0.7
2.0
1.1
0.7
2.4
1.3
1.8
1.1
2.5
0.7
1.0
2.0
1.0
1.2
1.18

YIR035C
1.4
1.8
0.9
1.6
0.7
2.1
1.3
1.3
0.7
1.2
1.3
0.9
1.1
1.1
1.4
1.0
1.1
0.9
1.51

YJL132W
1.0
0.7
0.8
1.6
1.3
2.0
1.7
1.0
1.6
1.4
1.4
1.0
1.3
1.4
1.1
2.1
1.3
1.5
0.37

YJL196C
0.9
0.9
2.5
1.3
1.1
2.0
0.7
0.7
1.1
0.9
2.3
1.1
0.6
0.8
0.6
1.7
0.9
1.9
2.85

YJR142W
1.2
0.6
1.1
1.1
1.3
2.4
1.7
1.0
0.6
0.8
0.9
0.8
1.6
1.3
0.6
2.0
1.2
1.4
0.94

YKL067W
1.1
1.9
2.1
1.4
1.9
2.2
2.6
1.2
0.9
1.6
1.8
0.9
1.7
1.2
1.1
2.4
1.4
3.2
3.29

YLR142W
4.4
2.7
1.1
6.1
1.3
3.1
1.2
2.1
3.1
4.4
3.8
0.8
1.2
2.1
1.6
3.4
1.9
3.2
0.28

YML110C
1.1
0.8
1.9
1.6
0.8
2.6
2.0
1.4
2.7
2.2
1.7
1.1
1.8
1.4
1.3
2.3
1.1
1.6
2.01

YMR272C
0.7
1.0
1.6
0.7
1.1
2.6
1.0
0.8
0.4
0.6
0.8
1.2
1.2
0.8
1.1
1.5
1.3
1.4
1.66

YNL130C
0.6
0.7
2.4
0.7
0.8
2.4
1.3
0.8
1.7
2.4
1.5
0.9
1.9
1.0
2.5
0.7
0.7
1.2
1.18

YPR006C
1.9
1.5
0.5
1.9
2.0
2.4
2.8
1.5
1.5
3.9
2.4
1.1
1.8
1.2
0.7
1.6
1.8
2.1
0.46

YBR050C
2.4
1.9
1.9
3.1
1.0
4.1
2.6
1.7
5.8
3.2
1.1
1.0
1.3
1.3
0.5
1.7
1.5
1.8
0.41

YBR145W
1.5
0.7
2.8
0.9
1.1
11.5
58.8
1.0
0.1
1.1
1.1
1.0
2.0
2.2
1.2
3.6
1.7
2.0
2.17

YBR299W
1.8
0.9
1.1
3.5
1.6
0.8
3.6
2.2
1.1
5.3
2.4
1.2
0.7
1.4
0.6
3.9
1.0
1.1
0.32

YEL020C
1.0
1.5
0.8
2.9
1.5
1.3
2.4
1.2
1.4
1.1
1.3
0.8
1.2
1.0
1.4
2.1
1.2
1.3
0.31

YGL039W
0.8
1.4
2.1
1.3
1.3
1.7
4.2
1.3
0.7
2.8
1.1
1.3
1.5
0.9
1.5
1.5
0.6
1.0
1.09

YGL134W
0.9
1.3
0.5
0.8
1.4
1.2
2.3
1.4
1.1
1.4
1.1
0.9
0.7
1.1
0.5
1.7
0.9
1.3
0.53

YJR159W
1.4
2.3
1.3
1.7
0.9
1.4
2.3
2.7
5.2
2.8
2.2
1.5
2.1
2.0
2.3
5.2
1.7
2.3
0.30

YOL157C
1.0
1.1
1.3
2.5
1.4
0.9
2.7
1.4
2.3
4.8
1.2
1.2
1.4
1.2
1.1
3.5
1.4
1.3
0.41

YOR344C
1.1
1.1
0.4
0.7
1.9
2.0
2.4
1.4
0.3
0.9
0.6
1.3
1.8
0.6
0.7
0.6
1.3
1.3
2.11

YPL265W
0.7
0.4
2.3
1.1
1.0
2.3
8.9
2.3
0.2
1.2
1.8
0.9
1.1
1.1
1.2
2.0
0.5
0.4
1.42

YBR126C
0.8
1.9
5.6
1.2
0.7
2.9
2.3
0.6
1.7

1.1
1.3
2.1
0.7
1.0
1.7
1.5
1.3
1.96

YCR005C
1.1
1.9
2.0
1.2
0.9
1.6
4.4
1.2
1.5
1.5
2.1
0.5
0.7
0.8
0.7
0.7
1.6
1.7
2.38

YDR452W
1.1
1.1
1.3
0.8
1.2
2.0
1.9
1.0
1.4
1.3
1.5
0.9
1.4
1.2
1.3
1.3
1.9
2.2
1.54

YGR019W
1.2
0.8
1.4
1.7
0.8
2.4
2.4
1.2
2.9

1.1
1.2
2.1
1.3
2.2
2.4
1.3
2.0
0.79

YGR255C
0.9
1.4
1.4
1.5
1.3
3.2
1.8
1.0
2.5
1.8
2.0
1.3
2.5
0.9
1.0
1.1
1.1
1.1
0.81

YIL098C
1.4
1.6
0.5
2.0
1.7
1.7
2.2
1.6
1.9
1.9
1.4
0.8
1.3
1.9
0.7
2.0
1.2
1.6
0.75

YIL172C
1.1
1.1
1.6
1.7

1.3
2.5
1.6
2.8
7.1
1.0
1.4
2.0
1.3
1.4
2.8
1.1
1.2
0.42

YLR100W
0.8
1.4
1.3
1.9
1.8
1.8
2.3
1.0
0.9
1.0
0.9
1.1
1.6
1.1
0.6
1.9
1.5
2.1
1.88

YOR221C
0.8
1.0
0.9
1.1
1.7
0.8
2.1
0.9
1.4
1.7
1.1
0.8
1.0
1.1
1.0
1.4
0.9
1.2
0.39

YPL123C
1.2
0.8
1.8
3.0
0.8
1.9
2.7
1.2
4.2
2.3
1.9
1.0
2.2
1.6
1.4
2.6
1.6
3.2
0.71

YBR093C
2.9
1.2
1.7
1.3
1.1
0.6
0.3
1.7
0.1
0.5
3.1
2.0
0.2
1.3
2.7
0.4
0.8
1.9
3.33

YBR196C
0.8
0.6
3.9
1.4
0.8
0.8
1.4
1.1
0.3
0.9
2.3
1.0
1.4
0.5
1.9
1.1
0.8
1.0
6.60

YER023W
0.8
0.6
1.2
1.2
0.8
1.3
0.7
0.9
1.1
0.6
2.1
0.8
1.2
0.7
1.2
1.6
1.5
1.4
1.77

YFL055W
2.0
6.7
1.3
2.5
1.5
1.1
1.4
1.3
23.9
6.5
2.7
0.9
1.3
1.5
0.7
1.4
1.4
1.0
0.23

YIL124W
0.9
0.8
2.8
1.6
0.9
1.2
1.3
0.9
1.0
0.7
2.8
1.1
0.9
1.1
0.6
3.1
1.2
2.1
2.39

YMR318C
1.4
2.4
2.2
0.7
1.2
2.1
0.8
3.6
2.3
4.8
3.6
0.8
1.8
1.7
1.5
1.1
1.1
1.1
3.17

YBR067C
1.6
2.5
2.8
0.9
1.1
1.1
1.1
1.1
1.7
1.0
3.1
1.0
0.9
0.7
3.3
2.5
0.5
0.4
1.76

YBR115C
0.6
0.7
1.4
0.4
0.7
0.9
1.1
1.3
0.8
1.6
1.8
0.9
2.3
0.7
1.1
0.5
0.6
0.6
0.64

YDL131W
1.1
0.9
1.8
1.0
1.0
0.9
0.7
2.2
0.8
2.7
2.2
1.2
1.0
0.9
1.1
0.9
0.7
0.6
1.81

YDL168W
2.3
2.0
2.1
0.9
1.2
1.4
1.1
1.7
8.2
4.7
1.9
0.6
1.3
1.6
1.2
1.1
0.9
0.8
1.08

YDR216W
1.3
1.1
2.0
2.6
0.8
1.3
1.0
1.0
2.5
2.7
2.1
1.0
2.4
0.9
2.5
1.6
1.0
1.8
0.44

YDR253C
5.7
6.4
1.4
3.2
0.9
0.8
1.0
1.7
14.8
6.3
2.3
1.0
2.2
3.6
1.2
1.6
1.0
1.0
0.38

YDR513W
2.2
2.5
2.3
2.6
0.9
2.1
1.6
1.6
4.6
3.1
2.0
0.9
1.8
2.0
1.3
3.8
1.3
3.2
3.10

YER061C
0.9
0.9
1.2
2.5
0.8
0.4
0.9
0.7
0.3
0.7
2.2
0.7
0.9
1.0
0.8
1.8
1.2
1.2
0.84

YFL052W
1.3
0.8
0.7
2.3
1.5
2.1
1.4
1.3
0.6
1.2
2.3
0.8
1.0
1.6
0.4
1.0
1.1
0.9
0.32

YFL058W
1.2
1.7
1.1
1.4
1.1
2.0
0.9
1.7
3.2
2.4
2.4
1.2
1.2
1.0
1.7
0.7
1.1
0.9
0.40

YFR030W
3.1
5.5
8.5
0.5
0.8
1.8
1.1
1.7
24.1
9.0
2.4
2.4
4.1
1.3
1.7
1.6
1.3
0.9
0.30

YGL202W
0.8
0.7
2.2
0.7
0.7
0.7
0.6
1.0
1.3
1.7
2.4
0.9
1.1
0.8
2.2
0.6
1.3
0.9
1.70

YGR070W
1.1
1.0
2.0
1.5
1.4

1.4
1.8
1.1
1.5
1.8
0.6
1.4
1.0
2.6
2.3
1.2
1.3
0.40

YHL036W
2.2
4.8
3.4
2.0
1.3
1.3
1.0
1.2
9.0
4.4
2.3
1.2
1.5
1.2
0.9
1.1
1.0
1.0
0.60

YHR104W
1.0
4.1
15.7
1.9
1.1
1.2
1.5
1.1
4.8
2.3
2.6
1.0
1.2
1.5
1.6
1.3
1.9
1.9
1.57

YJL045W
1.8
2.2
1.6
5.3
0.7
0.6
0.7
0.9
9.7
1.6
2.3
1.1
1.6
1.2
3.4
2.4
0.9
0.9
0.42

YJL060W
1.8
2.6
9.6
1.0
1.4
1.3
1.3
0.8
5.3
2.8
1.6
1.5
2.1
1.7
1.4
1.5
1.2
1.1
0.95

YJL155C
2.1
5.0
0.8
2.4
0.8
0.8
2.0
1.5
3.8
2.8
2.4
1.0
6.6
1.2
1.2
2.3
1.8
3.1
0.60

YJR109C
0.8
0.7
1.4
0.9
0.7
0.9
0.8
1.0
1.8
4.3
1.5
1.4
3.1
0.9
1.3
0.5
1.1
0.6
0.84

YJR156C
1.6
3.2
2.4
1.8
0.9
0.9
1.3
1.5
3.4
2.8
3.0
1.1
1.6
2.4
3.0
2.3
0.8
1.1
0.24

YLR092W
5.0
7.5
1.4
0.6
1.3
1.0
1.3
1.5
12.7
5.8
3.1
1.0
1.8
1.4
0.9
1.2
1.0
1.1
0.24

YMR081C
3.5
1.4
2.0
5.8
1.7
1.1
0.9
1.7
0.3
2.2
2.5
1.1
0.7
1.8
0.2
3.0
1.9
3.0
0.62

YMR250W
0.9
5.1
5.6
1.3
0.6
4.5
3.0
0.9
6.1
2.4
4.3
1.2
2.6
1.1
2.0
5.0
1.2
3.0
0.84

YNL277W
5.7
10.3
5.3
0.6
1.1
1.7
1.4
2.2
55.0
10.9
3.2
1.3
1.8
1.5
0.6
1.3
0.9
0.7
0.27

YOR184W
1.1
0.9
2.1
2.1
1.0
0.6
1.2
0.7
0.9
0.7
2.7
0.7
0.6
0.7
1.0
0.9
1.2
1.2
3.19

YPR160W
1.4
3.8
3.6
3.3
0.7
4.5
1.8
0.9
0.9
1.3
4.4
2.1
2.2
1.1
1.4
5.3
1.0
2.9
1.42

YDL182W
0.8
0.7
1.3
0.8
1.3
1.0
1.0
2.9
0.8
2.4
2.0
1.4
1.5
0.8
0.7
1.1
0.6
0.6
2.31

YBR291C
2.0
0.9
1.0
1.5
0.9
1.1
0.9
2.2
0.9
1.0
1.1
0.9
1.0
1.7
0.5
1.5
0.9
1.3
1.19

YIL094C
1.5
0.4
0.8
0.7
1.4
1.2
1.3
3.6
0.3
0.4
1.8
1.0
0.7
1.0
0.5
0.9
0.9
1.0
2.26

YNR050C
1.7
0.5
1.2
0.6
1.3
0.9
1.0
2.2
0.4
0.7
1.5
1.0
1.1
0.6
0.3
1.4
0.6
0.7
2.13

YDL244W
1.1
3.5
1.8
1.6
0.9
1.3
1.7
1.8
2.5
3.7
1.2
1.2
2.0
2.0
2.9
1.5
1.1
1.0
0.25

YDR054C
1.3
1.0
0.7
1.4
0.7
1.0
1.1
1.5
2.9
3.2
1.9
1.0
2.5
1.1
1.6
1.4
0.8
1.4
1.18

YDR353W
0.9
1.6
3.4
1.6
0.6
0.9
1.0
1.1
2.0
5.1
1.4
0.8
0.7
1.6
1.3
1.0
0.9
1.3
3.20

YEL070W
1.4
0.9
1.6
3.4
1.3
1.2
1.3
1.2
1.9
13.0
1.1
1.1
1.1
2.1
3.2
1.9
0.9
1.0
0.27

YIL168W
2.8
1.4
1.0
1.2
1.4
0.7
1.3
1.6
7.8
19.3
1.9
0.8
0.9
1.5
1.2
1.2
1.0
1.1
0.39

YJL221C
1.1
1.0
1.1
1.3
0.9
6.6
2.5
1.8
2.7
4.4
0.8
1.1
1.4
1.1
1.1
3.3
1.1
1.4
0.41

YJR095W
1.2
20.5
1.9
6.7
1.2
1.5
2.0
0.9
0.5
6.3
0.6
0.7
0.8
1.3
0.8
0.8
1.3
0.9
0.23

YKL085W
1.4
2.3
1.6
1.2
1.2
1.9
1.5
1.2
1.9
3.0
1.8
0.8
1.5
1.0
0.5
1.7
0.9
1.3
2.16

YKL188C
1.3
0.7
1.9
2.4
1.0
0.8
1.1
0.7
2.5
2.8
1.1
1.2
1.2
2.1
1.4
2.7
1.1
1.5
0.27

YKL217W
1.8
2.4
1.0
2.1
1.1
1.2
1.6
1.1
0.9
4.1
1.6
0.8
1.2
1.2
2.2
3.0
1.7
3.3
0.29

YKR061W
2.0
0.9
0.5
1.9
1.2
1.2
1.4
1.5
1.5
2.6
1.1
0.9
0.9
1.6
0.9
0.8
1.5
1.6
0.70

YLR174W
1.2
1.5
1.7
2.1
0.9
0.9
1.6
1.1
2.5
8.3
1.3
1.3
1.8
1.7
0.8
4.6
0.9
1.2
0.41

YLR260W
1.1
1.5
1.5
2.4
1.2
1.0
1.2
1.2
2.6
3.2
0.6
0.8
1.9
1.2
1.0
1.0
1.1
1.2
0.44

YNL009W
1.1
1.9
2.0
1.4
1.4
1.1
1.2
1.1
1.4
3.3
1.3
0.9
1.3
1.3
2.7
3.3
1.2
2.3
0.45

YNL117W
0.9
4.7
1.7
0.8
0.8

1.1
1.7
12.8
4.4
1.4
0.7
1.3
2.0
2.6
1.6
1.1
0.9
0.24

YNL183C
0.9
3.5
6.4
1.3
0.7
1.2
1.3
0.9
4.8
4.3
1.3
1.1
2.3
1.1
1.1
1.2
0.8
1.0
0.47

YNR073C
1.1
1.4
0.8
2.7
1.4
1.7
2.2
1.5
2.5
16.8
2.2
1.1
1.2
2.3
1.7
1.6
1.0
0.9
0.18

YPL161C
1.0
1.7
1.1
1.1
0.8
0.7
1.3
1.8
1.2
2.7
1.0
1.0
1.2
1.1
0.8
1.4
1.3
1.3
0.41

YAL061W
1.7
2.4
3.3
3.8
1.0
1.0
2.0
0.8
5.5
1.4
4.1
1.1
1.4
0.7
0.6
1.1
1.4
1.2
0.88

YAL067C
2.7
7.5
1.5
1.4
0.7
1.2
0.8
1.1
7.6
2.9
1.2
1.0
1.1
1.3
2.4
1.6
1.0
1.0
0.33

YBL033C
1.3
1.9
2.4
1.0
1.1
0.4
0.9
1.4
6.6
4.2
1.1
0.9
1.8
1.4
1.0
1.2
1.2
1.0
0.53

YBL086C
0.8
0.5
1.0
0.6
1.3
0.7
1.0
1.1
3.3
1.4
1.3
0.5
0.9
0.8
0.5
1.4
0.9
1.0
0.43

YBR117C
0.8
1.6
1.5
1.4
0.9
2.3
1.0
0.7
5.9
1.5
0.4
0.8
2.1
0.9
1.0
12.0
0.7
0.7
0.49

YBR213W
1.0
1.6
1.0
0.5
1.1
2.4
1.3
1.3
11.4
2.3
0.5
1.2
1.4
1.3
1.7
0.8
0.9
0.9
0.23

YCR036W
1.3
1.2
1.3
1.3
1.5
1.4
1.5
1.1
2.6
1.5
1.0
1.3
1.8
1.5
1.7
1.6
1.6
1.7
1.35

YDL132W
0.8
1.2
1.1
0.7
1.3
0.9
1.4
1.0
3.8
2.4
1.3
0.7
2.0
0.9
1.7
1.0
0.9
1.1
0.74

YER014W
1.0
0.9
0.9
0.6
0.8
4.0

1.2
3.5
1.1
0.9
1.1
1.5
1.2
2.3
0.8
1.0
0.9
0.43

YER042W
3.0
2.2
3.1
1.0
1.1
1.6
1.1
1.7
6.8
2.1
1.8
1.1
1.4
5.2
1.0
1.9
0.7
1.1
1.80

YER090W
1.0
1.1
2.0
0.7
1.3
0.7
0.9
1.4
3.7
2.5
1.8
1.3
1.2
1.2
1.5
0.8
1.1
0.9
0.97

YGL026C
0.7
9.3
1.9
0.6
1.2
1.7
0.9
0.8
3.7
1.5
3.4
1.3
1.8
0.9
2.4
0.7
1.5
0.8
0.87

YGL252C
1.1
2.4
1.4
0.7
1.3
0.8
1.4
1.2
2.7
1.7
0.9
0.9
1.2
1.0
1.3
1.2
1.0
1.3
0.91

YGL254W
1.2
1.1
0.8
0.6
1.1
0.7
1.3
1.4
3.1
1.8
1.1
1.2
2.4
1.3
1.1
1.4
0.8
1.2
0.53

YGR276C
0.9
0.8
0.3
1.3
1.5
0.7
1.9
1.5
4.5
2.2
0.9
1.0
1.8
1.0
0.8
1.3
0.9
1.1
0.97

YHR106W
0.9
1.7
1.7
1.5
1.7
1.3
1.2
1.0
2.8
2.5
1.4
0.7
1.0
1.2
0.9
2.4
1.3
1.1
1.73

YIL046W
1.5
2.7
1.6
0.7
1.4
0.9
1.0
1.0
10.7
2.5
1.2
1.0
1.7
1.1
1.3
1.8
9.0
5.8
0.68

YJL071W
1.0
1.5
1.3
1.6
1.4
1.0
1.3
1.1
2.8
2.2
1.3
1.1
1.0
1.0
1.5
1.2
0.9
0.9
0.41

YJR139C
1.4
2.6
2.9
1.1
1.2
1.8
1.3
1.1
4.1
1.9
1.5
1.0
1.5
1.4
0.7
1.2
1.0
1.3
4.47

YKR069W
3.4
6.3
5.0
3.1
0.7
0.5
1.0
1.2
10.9
9.0
2.0
1.4
1.4
1.7
1.1
1.8
1.0
1.0
0.25

YLL061W
3.6
2.8
9.2
0.4
0.8
0.8
0.9
1.4
3.7
5.5
1.7
0.7
0.9
1.3
1.4
1.0
0.6
0.7
0.33

YLR070C
1.0
1.3
1.4
1.1
0.7
1.1
1.3
1.0
3.5
1.6
0.4
0.7
2.0
1.3
0.5
2.1
1.0
0.9
0.31

YLR099C
2.0
2.2
1.4
0.8
0.9
0.4
0.2
1.2
3.6
1.1
1.2
0.9
0.8
0.7
0.9
0.7
0.7
0.5
0.92

YLR157C
1.1
1.1
3.4
1.1
1.3
1.9
1.9
1.5
5.1
1.8
1.9
1.2
1.8
1.1
1.1
2.1
1.6
2.1
1.70

YLR160C
1.2
1.4
3.9
1.1
1.3
1.8
1.9
2.0
4.8
1.8
1.6
1.2
2.0
1.2
1.0
2.0
1.6
2.2
1.59

YLR164W
1.0
2.4
0.3
1.0
1.2
1.2
1.1
1.2
5.3
2.0
3.2
0.7
1.0
1.5
0.7
11.0
1.5
1.2
0.31

YML042W
0.9
1.4
1.5
2.2
1.0
0.9
0.8
1.6
3.8
2.4
2.5
1.0
1.2
1.4
1.7
4.8
1.0
0.9
0.29

YOL049W
0.9
1.1
1.3
0.9
1.4
0.6
1.1
1.0
3.0
1.9
1.8
0.8
0.9
0.9
0.7
1.3
1.0
1.3
1.61

YOL064C
1.4
2.1
1.1
0.6
0.9
1.4
1.2
1.0
8.7
2.7
1.0
0.9
2.0
0.9
1.0
1.7
1.2
1.3
1.32

YOR377W
0.6
0.6
0.6
1.0
1.4
1.6
1.6
1.0
3.8
1.1
1.2
0.9
1.3
0.9
1.2
1.3
1.1
1.1
0.46

YPL031C
0.9
2.0
1.4
0.8
1.5
1.8
1.6
1.0
5.7
1.4
1.4
0.8
1.6
0.9
0.7
2.0
1.4
1.2
0.49

YPL113C
1.4
1.7
0.4
2.4
1.3
1.0
1.9
1.4
5.5
2.0
1.5
1.1
1.7
1.6
0.9
2.5
1.2
1.7
0.28

YPL274W
0.8
4.2
3.8
0.8
0.6
1.1
0.7
0.9
4.1
3.6
2.0
0.5
0.6
0.9
1.5
1.1
0.7
0.6
0.41

YPR048W
1.3
2.0
0.9
1.1
0.9
0.6
0.9
1.5
4.0
2.1
1.0
0.8
0.6
1.2
0.6
0.8
0.7
0.8
0.75

YBR001C
0.9
1.4
1.1
1.4
0.9
1.1
0.9
1.3
2.3
2.1
1.0
1.0
2.0
1.2
1.8
1.4
1.0
1.6
0.61

YBR018C
0.9
1.1
1.9
2.9
0.9
0.7
1.4
0.6
1.3
1.7
5.8
1.0
1.0
2.4
1.3
6.2
0.8
0.9
0.20

YBR204C
1.0
1.0
1.5
1.8
1.1
0.9
1.7
1.1
1.8
1.9
2.2
1.0
1.7
1.4
1.2
2.3
1.1
1.5
0.84

YBR241C
0.9
9.3
2.6
0.9
0.9
1.5
1.4
0.7
29.8
2.2
1.4
1.4
1.4
0.9
1.6
0.7
1.0
1.2
1.25

YCR105W
2.2
1.2
1.2
3.0
0.9
1.0
1.0
1.4
2.0
3.9
2.3
0.9
1.9
1.9
3.1
1.3
1.3
1.1
0.36

YDR287W
1.1
8.4
1.9
1.2
1.2
1.6
1.2
1.2
2.5
1.8
1.5
1.1
1.5
1.2
1.6
2.7
1.5
1.3
0.52

YDR294C
0.7
1.1
1.9
1.2
0.9
0.7
1.0
1.0
2.0
2.9
1.2
1.1
1.6
1.0
2.0
1.7
0.9
1.1
1.02

YER052C
1.1
1.0
3.6
1.1
0.6
0.6
0.5
1.0
2.7
2.4
1.1
0.9
2.1
0.7
1.2
0.2
0.8
0.4
1.54

YFL021W
0.8
1.4
2.4
1.7
1.1
0.8
0.8
0.6
2.7
1.2
1.3
0.9
1.5
1.1
1.3
1.0
0.8
0.5
0.40

YGL040C
0.7
1.2
1.4
0.9
1.3
2.0
1.1
1.0
2.1
1.9
0.9
0.6
1.6
1.3
0.7
1.5
0.7
1.0
1.77

YGL125W
1.0
3.2
4.3
0.7
0.9

1.7
0.8
2.1
2.1
1.6
1.0
1.4
1.0
1.9
1.2
1.2
1.1
0.27

YGR007W
1.3
1.7
0.7
1.6
0.6
0.8
1.2
1.1
2.2
2.3
0.9
0.8
1.4
1.8
1.9
1.3
1.1
1.4
0.74

YGR155W
1.3
4.4
1.2
0.6
1.3
1.6
1.1
1.4
2.4
1.7
1.3
1.0
1.4
0.7
0.5
1.0
0.5
0.6
4.15

YIL099W
0.9
1.6
1.5
0.4
0.8

101.4
1.0
2.2
1.8
0.9
0.9
1.4
1.6
5.5
1.2
1.0
1.1
0.18

YIL170W
1.1
1.0
2.5
2.2
0.9
8.8
0.5
1.2
5.7
3.2
1.7
0.7
1.9
1.1
2.3
1.8
1.6
1.5
0.48

YIR031C
0.8
1.6
0.6
0.6
1.6
1.7
1.4
1.0
2.6
1.0
1.2
0.8
1.0
1.2
0.8
0.7
0.9
0.8
0.44

YIR032C
1.1
1.9
1.3
2.6
1.0
0.6
1.0
1.2
2.6
2.3
1.4
1.0
1.4
1.6
0.6
1.6
0.9
1.1
0.40

YJL128C
0.8
1.4
0.4
0.8
1.2
1.3
1.8
0.9
2.0
1.7
0.6
1.0
1.7
0.8
1.2
0.9
1.0
1.0
0.42

YJR090C
0.8
1.0
0.6
0.8
1.2
1.2
0.8
0.8
1.9
1.2
0.4
0.8
2.2
1.0
1.6
0.8
1.1
1.0
0.60

YJR103W
1.1
3.8
1.2
1.6
0.7
0.6
0.6
0.8
1.8
3.0
1.1
0.6
0.7
0.7
3.2
2.3
0.9
1.0
0.74

YJR153W
1.1
1.7
1.1
0.8
0.9
0.4
1.3
0.9
2.4
1.6
2.0
0.7
1.3
1.7
2.9
1.6
0.8
1.0
0.18

YKL192C
1.1
1.0
3.7
1.1
1.1
1.8
1.1
0.9
3.5
1.6
1.1
1.2
1.7
1.5
1.2
2.1
1.0
0.8
1.57

YLR025W
1.2
5.1
0.7
1.1
1.9
1.5
1.7
1.5
2.4
1.5
1.1
0.9
1.0
1.7
1.5
2.2
1.2
1.3
1.15

YML051W
1.0
1.4
1.8
0.9
1.0
0.7
0.9
0.9
2.0
1.5
1.4
0.7
1.2
1.1
1.4
1.1
0.7
1.0
0.57

YML099C
0.6
1.0
1.1
1.3
1.0
0.5
1.0
0.7
2.2
1.7
1.6
1.1
1.3
0.9
1.0
1.6
0.7
0.8
0.48

YMR056C
1.1
1.3
1.7
1.0
1.1
0.9
1.4
1.2
1.8
1.1
1.6
0.9
0.9
1.1
0.7
2.4
1.0
1.1
0.72

YNL257C
0.7
1.0
0.9
0.8
0.9
2.0
1.1
1.1
2.1
1.4
1.0
1.1
1.7
0.8
1.0
1.4
0.9
1.3
0.63

YNL264C
1.0
2.4
1.3
1.0
0.8
1.4
1.5
1.1
3.3
1.3
1.0
1.1
1.5
1.2
1.1
1.3
0.7
1.1
0.48

YNR071C
1.4
1.0
0.9
3.2
1.1
0.9
1.4
1.2
3.1
7.0
1.3
0.6
1.7
1.1
1.8
1.0
1.0
0.9
0.16

YOL065C
1.0
1.7
1.6
1.3
0.8
1.3
1.9
1.0
2.1
1.8
1.0
0.8
1.3
1.1
0.7
2.6
1.1
1.5
0.43

YOL067C
0.8
0.9
0.9
1.4
0.7
0.3
0.7
1.0
2.1
1.3
1.3
0.7
1.7
0.7
1.2
1.1
1.4
0.9
0.55

YPL147W
1.0
0.8
2.3
1.2
1.2
1.1
1.0
0.9
2.4
2.4
1.3
0.9
1.5
1.0
2.4
2.5
1.5
3.6
0.33

YDR043C
2.8
1.1
1.2
6.9
1.7
1.4
1.3
1.2
1.0
2.7
1.3
0.9
0.7
1.8
1.2
1.4
1.9
1.2
0.66

YGR180C
3.1
1.1
1.9
1.0
2.0
0.6
0.5
1.0
1.4
1.5
1.0
0.9
0.9
0.9
1.3
1.2
1.0
1.9
3.90

YJL026W
2.5
2.4
2.9
1.0
1.7
1.4
0.5
1.2
1.0
1.1
1.3
1.0
1.2
1.0
1.1
1.6
1.4
2.1
3.74

YGR087C
1.0
15.0
1.7
0.6
1.0
1.1
1.0
0.8
0.2
0.9
0.8
1.2
1.2
0.7
3.5
0.6
1.0
0.6
1.88

YGL256W
0.9
5.3
1.1
1.3
0.7
0.7
0.5
1.0
0.4
1.2
1.0
0.9
0.8
0.9
1.0
0.7
0.7
0.8
0.90

YAL039C
1.1
2.2
1.7
1.0
1.1
0.8
1.0
1.2
1.6
2.2
1.1
1.4
1.6
1.2
3.3
2.2
1.4
1.1
0.39

YJR107W
1.0
3.1
1.5
1.8
0.7
1.5
1.3
1.3
1.4
0.9
1.3
1.1
1.7
1.4
1.1
1.1
1.4
1.3
0.41

YNL142W
0.7
2.4
2.5
0.8
1.3
0.9
1.1
0.8
0.9
0.6
0.9
1.2
0.9
0.8
0.3
1.0
1.0
0.9
0.44

YDL210W
1.2
2.2
2.7
1.1
0.9
1.3
0.8
1.1
1.2
1.4
0.6
0.8
1.2
1.1
1.9
0.9
1.1
0.9
0.20

YGL055W
1.1
1.8
0.3
2.5
1.5
1.6
0.6
1.4
0.2
0.7
0.9
1.3
0.2
0.7
0.5
3.0
1.0
1.5
5.60

YCL025C
1.1
4.6
2.5
1.7
0.9
0.9
0.7
0.7
0.3
0.3
1.0
1.1
0.5
0.7
0.8
0.6
0.6
0.6
1.98

YBR132C
0.9
1.9
2.4
1.8
0.8
1.2
1.1
0.8
0.8
1.1
1.9
1.0
1.4
1.1
1.5
1.3
1.1
1.3
0.43

YHL018W
0.8
1.5
0.5
0.5
0.9
0.4
1.2
0.8
0.8
0.6
1.2
0.7
0.8
1.0
0.9
0.9
1.0
0.9
0.37

YPL038W
0.8
1.5
0.2
1.1
1.4
0.5
1.0
1.2
0.9
0.7
1.1
0.6
0.6
0.9
0.6
0.8
0.9
0.9
0.64

YKR053C
0.9
2.0
1.0
1.2
1.0
1.1
1.7
0.9
0.8
1.8
0.5
0.7
0.7
1.3
0.3
0.9
2.8
2.4
0.35

YNL256W
0.7
1.6
0.6
0.6
1.0
0.5
0.6
0.9
0.8
0.6
0.6
0.6
1.3
0.7
0.9
0.4
0.6
0.6
1.09

YLR377C
1.1
2.6
1.8
1.2
1.0
0.7
0.9
0.7
1.8
1.6
0.6
0.6
1.2
2.9
0.8
2.7
0.9
1.4
0.14

YBR253W
1.3
4.4
0.4
1.1
1.4
1.3
1.4
1.8
1.8
1.5
1.1
1.0
0.8
1.2
0.9
1.3
1.3
1.1
0.96

YBL030C
1.0
0.9
4.5
0.9
0.7
1.1
0.9
0.8
0.4
0.9
1.1
0.9
0.5
0.8
1.8
1.0
1.0
1.1
3.12

YBR221C
0.8
0.7
3.2
1.5
1.3
1.7
1.5
0.8
1.0
1.3
1.2
1.3
1.7
0.8
1.1
1.5
0.9
1.0
3.62

YDR342C
2.8
1.1
12.2
5.7
1.6
1.1
0.8
1.2
0.2
2.2
2.9
1.0
0.6
0.9
0.5
2.4
1.0
2.2
5.23

YDR343C
1.2
1.0
20.6
4.6
1.3
1.3
0.7
1.2
0.3
2.1
2.3
1.0
0.8
0.8
0.5
2.8
1.1
2.3
5.81

YEL034W
0.9
0.6
3.3
0.9
1.4
0.9
0.4
0.9
0.8
1.0
1.1
0.9
0.8
0.9
0.8
0.9
0.9
0.9
5.44

YHR094C
0.7
1.2
5.3
1.6
1.1
1.6
0.8
1.2
0.3
1.2
0.6
0.9
0.7
0.6
2.7
0.9
1.4
1.4
4.82

YIL162W
1.3
1.5
6.8
2.4
1.2
1.0
1.2
1.6
0.8
3.7
2.8
2.0
1.0
1.0
1.5
1.7
0.9
1.4
1.22

YJR105W
0.6
0.7
3.0
0.8
0.7
0.3
0.5
0.8
0.9
0.5
1.0
0.8
0.8
0.5
1.2
0.7
1.1
0.9
3.75

YLR134W
0.8
0.6
2.3
0.8
1.3
2.5
1.1
0.8
0.1
0.7
1.1
1.2
1.5
0.6
1.7
0.5
0.6
0.8
3.47

YLR258W
1.5
1.0
4.2
3.5
0.9
1.8
1.8
0.9
0.8
1.3
1.2
0.9
1.4
1.2
0.6
1.7
1.0
2.0
1.36

YML058W
1.9
1.2
5.8
1.9
0.6
0.6
0.6
0.7
1.1
1.2
3.3
0.9
1.4
1.1
2.5
1.3
1.3
1.5
2.14

YMR083W
1.4
1.7
2.6
1.1
1.5
1.8
1.7
1.1
0.4
1.1
1.6
0.7
0.9
0.8
1.3
1.3
0.9
1.1
2.52

YOR178C
1.4
1.3
4.8
2.3
1.0
2.7
0.9
0.9
0.2
1.7
4.1
1.7
1.0
1.0
1.1
1.7
1.0
1.5
0.56

YPL028W
0.7
0.9
2.6
0.9
1.0
1.2
1.3
0.9
1.2
0.8
1.2
1.4
0.9
0.8
0.6
2.2
1.4
1.8
4.35

YPR113W
1.1
0.8
3.7
1.3
2.0
1.1
1.2
0.9
0.4
0.8
2.0
0.7
0.7
1.3
1.0
2.3
1.2
1.9
2.85

YPR183W
0.9
1.5
3.5
0.8
0.9
1.2
1.2
1.0
0.9
0.6
2.5
1.2
1.6
0.7
0.9
0.8
1.2
1.0
1.17

YBR011C
1.3
1.8
2.5
1.1
0.9
2.0
1.1
1.3
2.2
1.0
1.7
1.1
1.5
0.9
2.1
1.7
0.8
1.1
3.68

YCR034W
0.8
0.4
2.5
0.9
0.9
0.3
0.3
0.9
0.1
0.2
0.8
0.5
0.2
0.6
0.9
0.3
0.9
0.7
3.77

YDR050C
1.6
1.3
2.3
1.8
0.9
1.7
1.5
1.3
0.4
1.3
2.0
1.4
2.0
1.2
1.9
1.3
1.1
2.3
6.26

YDR178W
2.0
2.0
3.4
2.2
0.9
2.1
0.6
0.9
0.9
0.8
2.0
1.3
1.5
1.5
0.7
3.0
1.2
2.3
2.27

YDR284C
0.8
1.5
3.0
2.9
0.8
1.8
1.4
0.9
0.9
1.0
1.3
0.9
1.2
1.3
0.9
1.7
1.5
1.5
1.44

YDR345C
0.8
0.9
5.6
2.6
1.3
1.2
1.1
1.2
0.2
1.1
1.5
1.4
1.2
0.8
0.8
1.0
1.3
1.8
5.65

YDR400W
1.0
2.0
2.2
0.7
1.0
1.1
0.6
1.4
1.1
1.4
1.3
0.4
0.7
0.9
0.8
1.1
1.1
0.8
0.56

YEL063C
0.7
0.8
2.4
1.3
1.2
1.3
0.7
0.6
0.8
1.7
0.8
1.1
1.1
0.8
1.3
1.0
0.7
0.7
1.12

YER081W
1.6
1.9
2.7
1.4
1.1
1.1
0.5
0.6
1.8
1.1
1.1
1.0
0.6
1.6
0.5
0.8
1.1
1.7
2.31

YER120W
0.9
1.1
2.5
0.8
0.8
1.5
0.9
0.6
0.8
0.9
1.1
1.3
1.0
0.9
1.5
1.0
1.2
1.0
1.52

YFL011W
1.2
0.7
3.7
3.3
1.3
1.0
0.8
0.8
0.3
1.6
2.1
0.9
0.8
0.8
1.7
1.2
0.8
1.0
1.25

YGL012W
1.0
0.8
3.0
1.2
1.5
1.6
0.9
0.8
0.3
0.9
0.6
0.6
0.3
0.8
0.6
1.2
0.9
1.1
4.88

YGR191W
0.8
0.7
1.6
1.5
0.8
1.1
0.7
0.7
0.1
0.7
1.6
0.7
1.0
0.7
1.5
0.7
0.8
0.8
1.58

YGR204W
0.5
1.1
2.7
1.3
0.6
0.6
0.8
0.4
0.9
2.3
2.1
1.0
1.3
0.5
1.6
0.6
1.0
0.7
1.49

YHR025W
0.6
0.8
2.4
0.6
0.9
0.8
0.8
0.8
0.2
0.4
2.1
0.9
0.7
0.6
2.1
0.5
1.0
0.6
0.68

YHR123W
0.7
1.2
1.8
1.0

1.0
0.9
0.8
0.8
1.1
1.2
0.7
1.5
0.8
2.3
0.5
1.1
1.0
0.85

YJL121C
1.0
0.5
1.9
0.8
1.0
1.1
0.7
1.0
0.1
0.4
1.1
0.6
0.7
0.9
1.0
0.6
1.1
1.0
1.00

YJR077C
1.1
1.1
2.0
1.6
0.9
0.9
0.7
0.8
0.4
0.7
1.6
1.0
0.9
0.7
1.5
0.7
1.0
0.8
1.79

YJR143C
0.6
0.6
2.1
0.8
1.6
0.6
0.5
0.7
0.1
0.3
1.3
0.6
0.3
0.6
1.1
0.5
0.7
0.8
3.24

YKL060C
1.6
0.8
2.5
1.0
1.6
1.3
1.2
1.1
0.3
0.8
2.1
1.3
1.2
0.8
1.6
1.5
1.2
1.7
6.01

YKL148C
0.9
0.8
3.7
0.7
0.8
0.5
0.6
0.8
1.7
1.7
1.5
0.8
0.8
0.8
0.6
1.1
0.8
1.0
0.54

YKL157W
0.7
1.0
2.3
1.3
1.5
1.5
1.9
1.1
1.7
1.9
1.5
1.0
2.3
0.8
1.2
1.7
1.2
1.5
1.22

YLR044C
0.8
0.6
2.2
0.9
1.7
1.5
1.3
0.7
0.0
1.2
1.1
1.4
1.7
0.5
2.2
0.6
0.9
0.9
5.16

YLR056W
1.0
0.6
2.5
0.8
1.6
1.2
0.8
0.9
0.0
0.5
0.8
0.9
0.2
0.7
0.9
2.1
1.1
1.1
3.61

YLR058C
0.9
0.8
5.5
2.6
0.7
0.9
0.5
0.3
0.2
0.1
2.6
0.4
0.3
0.7
1.5
0.4
0.8
0.8
2.71

YLR081W
1.3
0.8
2.8
3.6
1.0
0.9
0.7
0.9
0.1
2.2
2.6
1.0
0.6
1.0
0.7
1.2
0.7
0.9
1.46

YLR089C
0.9
1.2
2.1
0.9
0.8
1.5
1.6
0.7
0.5
0.8
1.7
0.6
1.0
0.7
1.7
1.4
1.2
1.3
1.27

YLR284C
0.9
1.0
3.8
1.9
1.6
0.9
0.8
1.2
0.9
0.9
1.5
0.6
0.8
1.3
1.0
4.5
2.9
8.1
0.84

YLR304C
0.7
0.6
5.0
0.7
0.6
1.9
0.6
0.6
0.1
2.2
1.6
1.0
0.5
0.7
1.6
1.8
0.5
0.7
2.39

YLR354C
1.1
2.5
2.3
1.5
1.6
1.5
1.1
1.4
0.4
0.9
1.7
1.2
1.0
0.9
2.4
1.3
1.0
1.5
4.53

YLR372W
0.7
0.3
1.7
0.8
1.4
0.5
0.2
0.9
0.0
0.1
0.9
0.6
0.1
0.6
0.7
0.2
0.5
0.6
4.46

YML022W
0.9
0.6
2.0
1.1
1.3
0.8
0.6
1.1
0.3
0.6
1.2
0.6
0.2
0.9
0.6
0.6
0.5
0.7
4.93

YMR011W
1.3
1.0
9.4
5.5
0.9
0.6
0.8
1.1
0.0
0.7
1.5
0.8
0.4
0.6
0.6
1.2
1.3
1.6
4.95

YMR015C
0.7
0.7
1.9
0.9
1.7
1.3
0.4
0.7
0.1
0.3
1.0
0.9
0.4
0.8
1.2
1.5
1.0
1.0
2.51

YMR205C
0.5
0.7
2.3
0.8
1.2
1.2
0.9
0.7
0.3
0.8
1.0
1.1
1.3
0.5
0.9
0.9
0.6
0.5
4.75

YMR261C
0.7
1.6
3.6
0.8
0.9
0.6
1.3
0.7
1.6
1.3
0.8
0.9
1.6
0.6
0.8
1.6
0.7
1.1
0.78

YMR323W
0.8
1.1
2.9
1.1
0.7
0.4
1.1
0.8
0.5
1.3
2.5
1.2
1.8
1.2
37.3
0.6
1.1
0.6
1.04

YOL086C
1.1
0.5
2.2
1.1
1.9
1.7
1.9
0.8
0.1
1.2
2.6
1.3
1.7
0.6
1.6
1.4
1.1
1.3
4.19

YOL156W
1.1
0.7
2.5
1.1
1.2
1.2
1.0
1.0
2.3
2.1
1.1
0.9
1.7
0.9
1.9
0.9
0.9
0.9
0.53

YOR002W
0.8
1.1
1.9
0.9
1.1
1.1
1.0
0.9
0.8
0.9
1.2
0.5
0.6
0.9
1.5
0.8
0.9
1.1
1.49

YOR085W
0.7
0.8
1.9
1.0
1.0
0.6
0.6
0.7
0.5
0.6
1.1
0.8
1.0
0.7
1.8
0.8
0.9
0.9
1.86

YOR108W
0.8
0.9
2.3
0.6
1.1
1.6
1.2
0.9
0.4
1.1
1.4
0.7
1.3
0.9
0.7
1.0
1.1
1.1
1.07

YOR128C
0.9
0.7
2.1
2.1
1.1
1.0
0.7
0.6
0.3
0.4
0.8
0.5
0.4
0.7
1.6
0.5
1.2
1.2
2.14

YOR142W
1.0
1.2
3.4
1.0
1.4
1.6
1.0
0.8
1.1
1.5
1.5
0.8
1.4
0.8
1.1
0.8
0.9
1.0
1.31

YOR176W
0.7
2.6
2.7
0.9
1.0
0.9
0.5
1.0
1.0
0.5
1.4
1.3
1.5
0.8
0.8
1.4
1.2
2.1
1.23

YPL057C
1.9
1.1
3.2
3.1
1.9
0.6
0.6
1.0
0.4
1.4
1.6
1.0
1.3
0.7
1.1
2.5
2.2
2.0
2.08

YPL135W
0.9
1.2
2.5
1.2
1.6
1.3
1.2
1.0
0.5
2.8
1.3
1.1
1.2
1.1
1.5
1.2
1.5
1.7
1.50

YCR010C
1.6
1.6
1.6
4.2
1.7
1.3
1.3
0.8
0.9
4.7
1.1
0.8
1.0
1.2
1.2
2.8
1.9
1.5
0.26

YBR003W
0.9
0.8
1.0
1.9
0.7
1.2
1.1
0.9
1.0
1.3
1.3
0.8
1.2
0.8
0.7
2.0
1.1
1.3
1.06

YBR020W
1.0
0.5
1.9
1.9
1.0
0.8
0.7
1.0
−0.4
1.1
1.0
0.8
1.1
1.0
1.3
0.7
0.8
0.9
0.27

YDR123C
1.2
0.8
0.4
2.1
1.6
0.7
0.9
1.3
0.5
0.6
0.6
0.5
0.9
0.7
1.2
0.8
1.3
1.0
0.30

YDR277C
1.6
1.2
1.0
3.0
0.8
1.1
1.2
1.7
0.2
0.9
1.2
0.9
1.2
1.3
0.4
2.3
1.2
1.7
0.89

YDR408C
1.0
1.0
1.4
4.1
0.9
0.9
0.8
0.7
0.3
0.5
1.7
0.6
0.5
0.9
1.0
1.0
1.1
1.1
2.16

YDR483W
1.1
1.0
1.3
2.0
0.7
1.5
0.8
1.0
0.4
1.1
1.4
0.8
1.3
0.8
1.5
1.2
1.2
1.4
3.24

YGL115W
0.9
0.6
1.2
2.0
1.2
1.2
1.4
1.0
1.2
1.2
1.0
0.9
0.7
1.2
0.7
1.7
0.8
1.2
2.46

YGR096W
1.5
1.0
1.1
4.6
1.2
1.7
0.9
1.0
0.8
0.8
0.8
0.8
1.1
1.2
0.9
0.8
0.8
1.0
0.49

YGR288W
0.9
0.5
1.0
2.6
0.8

1.4
1.0
1.6
2.6
1.3
0.9
1.3
1.1
0.8
1.7
1.2
1.3
0.41

YHR210C
1.3
1.0
0.6
5.2
1.8
0.7
1.9
1.3
−0.1
0.9
1.5
0.5
0.4
1.0
0.5
1.5
1.4
1.2
0.33

YIL006W
1.0
1.1
1.4
2.9
0.8
0.3
0.8
0.6
0.9
1.1
1.0
0.9
0.8
1.0
1.5
1.7
0.8
0.9
0.28

YKR034W
0.9
1.5
1.1
4.7
0.9
0.9
0.7
1.5
0.5
0.6
0.0
0.7
1.2
1.1
1.7
0.6
0.8
1.0
0.26

YLR006C
0.7
0.7
0.9
6.2
1.6
0.9
1.1
0.9
1.1
1.1
1.5
0.7
0.8
1.0
0.9
0.8
1.6
1.0
0.40

YNL025C
0.9
1.4
1.4
12.8
0.7
0.5
1.2
1.0
1.1
1.8
1.1
0.8
1.3
1.2
1.4
2.9
0.7
1.3
0.37

YOL116W
1.1
1.0
0.9
2.8
1.7
0.7
1.5
1.3
0.6
1.8
1.0
0.6
0.8
0.9
0.7
1.9
1.1
1.4
0.47

YOR103C
1.1
0.8
1.3
1.8
1.5
1.0
1.2
1.0
0.8
0.9
1.0
1.2
0.8
1.2
1.4
1.3
1.1
1.5
2.84

YOR251C
1.1
1.0
1.3
1.8
0.8
0.9
1.0
1.1
0.8
0.8
1.0
0.9
1.0
1.1
0.6
1.2
0.9
1.3
1.34

YOR348C
1.1
0.7
1.2
2.0
0.9
0.7
0.8
0.8
0.5
0.4
1.1
0.7
1.1
1.2
1.6
1.7
0.9
0.9
0.18

YPL148C
1.2
0.8
0.9
2.3
1.1
0.6
1.0
0.9
0.7
1.5
3.5
0.7
0.6
1.6
0.6
1.6
1.0
1.1
0.48

YGL205W
0.9
0.9
0.7
0.8
1.1
1.6
0.8
1.2
0.5
0.6
0.4
1.1
1.0
1.0
2.0
4.1
3.9
9.1
0.24

YNL192W
1.1
1.2
1.5
1.6
0.9
0.6
1.0
0.8
0.6
1.8
1.1
1.1
2.7
0.7
2.1
0.8
2.3
2.8
1.31

YOL108C
1.4
1.5
0.4
1.9
2.1
0.9
1.1
1.3
1.6
0.9
1.1
1.0
1.3
0.9
1.5
1.8
1.5
2.7
0.87

YPR165W
1.3
0.7
1.6
1.0
1.5
1.8
1.0
1.0
0.9
0.7
1.0
0.8
1.0
1.0
0.9
1.0
2.3
2.7
3.64

YDR073W
1.7
0.9
0.7
1.4
1.2
1.3
1.2
1.3
0.5
1.2
1.0
0.8
0.6
1.2
0.8
1.6
1.8
2.3
1.27

YER015W
0.7
0.9
1.1
1.5
1.3
0.9
1.2
1.1
0.4
0.9
1.0
0.9
0.8
1.1
0.8
3.0
1.6
2.6
0.41

YJL167W
0.9
1.4
1.4
1.1
0.7
1.3
1.5
1.5
0.9
0.9
1.2
1.3
0.9
0.9
1.6
1.4
1.4
2.1
2.94

YJL216C
0.8
4.7
2.2
0.9
0.8

1.5
1.9
1.5
1.3
1.1
1.0
1.1
1.1
1.2
1.5
1.2
2.0
0.25

YKR009C
1.0
1.2
1.5
0.9
1.0
1.8
1.0
0.9
2.4
2.1
1.2
1.0
1.8
1.0
1.0
4.6
1.9
2.5
0.27

YOR180C
0.8
1.1
1.0
1.0
1.0
0.7
0.8
0.9
0.3
0.4
0.6
0.8
0.9
1.0
1.1
2.4
0.9
2.3
0.55

YBR036C
0.8
1.7
1.8
1.2
1.2
1.3
1.3
0.7
1.0
1.0
1.5
1.0
1.9
0.8
1.5
1.6
2.1
1.8
2.05

YDR297W
1.5
0.8
0.8
1.1
0.9
1.4
0.6
1.5
0.3
0.7
1.4
1.0
0.8
0.9
1.4
1.4
1.9
1.9
1.73

YDR387C
0.8
0.9
1.2
2.2
0.9
1.2
1.3
0.7
1.4
2.0
2.0
0.9
1.3
0.9
1.4
2.7
1.2
1.1
0.86

YOL096C
1.1
1.0
1.2
1.6
1.2
1.3
1.7
1.0
1.3
1.4
1.2
1.2
1.4
1.4
1.0
2.3
1.2
1.2
0.64

YPR184W
1.2
1.4
5.7
2.2
0.9
1.5
1.3
0.7
1.9
3.2
3.6
1.4
2.5
1.3
1.5
3.1
1.0
1.7
0.37

YBR298C
1.1
1.0
1.6
2.3
1.4
0.4
1.7
0.5
0.3
1.1
1.5
1.1
0.8
0.9
0.2
2.1
0.9
0.8
0.88

YDL078C
0.7
1.1
1.2
0.8
1.3
1.1
1.7
1.0
1.1
1.0
1.7
0.8
1.0
0.8
0.5
2.2
1.1
2.0
1.65

YDL215C
1.0
1.5
1.0
1.6
1.5
0.9
1.9
1.1
1.7
2.4
0.8
0.8
1.5
1.0
1.1
2.2
1.1
1.6
0.91

YGL035C
0.7
1.4
4.3
1.4
1.1
0.6
1.2
1.3
0.9
1.5
1.3
0.9
1.1
1.1
1.0
2.3
0.9
1.2
0.61

YGR287C
1.3
1.0
1.3
1.5
0.8
0.8
2.2
1.3
2.6
4.2
1.5
1.1
1.7
1.1
2.3
3.0
1.0
1.1
0.38

YJL070C
1.3
0.9
1.1
1.2
1.3
2.0
1.4
1.1
1.0
1.1
1.3
1.0
1.8
1.3
3.5
2.2
1.1
1.2
0.34

YLR351C
1.0
1.4
1.3
1.5
1.3
1.4
1.4
1.2
0.8
1.2
1.1
0.9
0.9
1.4
1.2
2.0
1.3
1.8
1.75

YLR375W
0.9
1.5
0.9
0.9
1.0
1.3
0.9
1.0
1.6
1.2
1.6
0.9
1.6
0.9
1.3
2.2
1.0
1.0
1.05

YMR267W
0.8
1.8
0.7
0.9
1.0
1.4
1.2
1.5
0.4
0.8
1.0
0.8
0.7
1.0
0.9
2.6
0.9
1.3
0.94

YMR278W
0.7
1.7
1.4
1.0
1.2
1.3
1.8
1.1
1.4
1.7
1.1
1.0
2.5
0.8
1.8
2.5
1.0
1.5
0.62

YMR293C
0.9
1.5
1.6
2.2
0.6
0.5
1.2
1.0
0.7
1.3
0.4
0.9
0.8
1.3
0.7
2.2
0.8
1.0
0.37

YNR072W
1.1
1.5
0.5
0.7
1.0
0.9
1.5
0.9
0.7
1.8
1.4
1.0
1.5
1.0
1.8
2.1
1.3
1.0
0.26

YOR363C
0.8
2.0
0.9
1.3
0.7
1.2
0.7
1.1
1.2
1.6
1.2
0.9
1.3
0.9
1.1
2.1
1.3
1.8
0.40

TABLE 8

Detoxification protein genes

The level of expressed mRNA in the presence of chemical substance/The level of expressed mRNA in the absence of chemical substance

yeast genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity

YDR453C
1.1
2.7
4.4
3.0
0.7
1.7
1.0
1.3
4.5
6.1
2.3
0.9
1.4
3.8
2.3
5.6
1.0
1.5
1.53

YLL060C
12.5
4.2
2.3
2.6
0.9
1.4
2.0
5.8
13.0
23.2
14.1
1.1
1.8
10.6
1.5
3.6
1.9
2.3
0.57

YBL064C
2.6
2.8
3.9
1.7
0.8
5.2
2.5
2.4
4.5
3.8
2.9
1.7
4.1
5.0
1.3
5.0
1.2
2.3
1.67

YBR008C
3.0
2.4
4.9
0.7
0.9
1.0
0.9
2.8
54.6
21.1
9.4
0.8
2.0
4.1
0.8
3.1
2.0
1.2
0.37

YOR153W
1.6
0.9
5.1
1.1
1.0
7.4
2.6
0.5
3.2
1.2
1.0
4.0
11.8
0.3
3.6
1.6
2.5
3.1
1.91

YHL047C
0.6
4.4
1.0
1.0
1.2
8.4
16.8
1.5
1.2
11.9
1.0
2.6
3.8
0.5
1.1
2.3
1.2
1.2
0.74

YCL035C
2.0
2.3
1.5
1.7
1.5
5.1
2.7
1.4
1.9
2.3
2.1
1.5
2.8
2.5
1.9
5.5
2.6
4.2
1.74

YGR197C
1.1
2.4
2.5
1.0
0.7
0.5
1.3
0.8
16.7
3.2
1.1
1.2
2.4
1.5
1.0
1.5
1.7
1.9
0.37

YHR055C
4.4
1.8
0.8
1.2
2.7
1.6
1.1
2.1
3.9
3.3
1.8
1.2
3.0
1.5
0.5
0.8
0.9
0.6
3.96

YNL239W
1.0
2.4
2.4
1.2
1.2
1.8
2.1
1.3
2.5
6.0
1.9
1.5
3.6
1.3
1.7
1.5
1.1
1.4
0.68

YNL241C
1.3
2.5
4.3
1.0
0.8
0.9
3.2
0.9
3.4
7.4
3.0
2.0
4.9
1.1
7.0
2.8
1.0
1.0
0.68

YBR293W
1.9
3.1
1.0
1.8
0.8
0.9
0.9
0.9
5.5
2.4
1.1
1.0
3.0
1.4
3.1
1.6
1.0
0.9
0.94

YDL100C
1.0
1.2
1.1
0.8
1.0
2.1
1.6
1.7
5.4
3.2
2.8
1.5
2.5
1.4
1.0
1.3
1.2
1.4
2.60

YER185W
2.0
3.1
2.1
7.0
1.6
1.2
1.1
1.0
2.9
1.2
1.6
1.1
2.1
1.6
1.7
0.6
2.6
1.1
0.26

YGL013C
0.9
1.2
0.8
0.7
1.1
2.3
0.9
1.4
3.0
1.5
0.9
1.0
2.3
0.8
1.0
0.9
1.1
1.0
0.43

YHR053C
3.5
2.1
0.7
1.1
2.9
1.3
1.2
2.2
4.5
2.9
1.4
1.1
1.9
1.5
0.3
0.7
1.0
0.5
3.99

YIR038C
1.3
3.5
4.6
2.0
0.7
2.5
2.0
1.3
4.6
4.5
3.4
1.1
2.5
2.5
1.2
6.0
2.8
2.0
1.11

YKL026C
2.7
2.0
1.2
4.9
1.0
1.8
2.5
1.8
7.5
3.0
3.0
1.0
2.3
1.8
0.8
6.6
1.6
3.3
0.61

YLL028W
0.6
0.9
4.6
0.5
0.9
1.7
1.0
0.7
1.2
2.3
0.7
1.3
4.1
0.7
3.1
0.6
1.2
1.2
1.02

YOR273C
0.7
1.0
1.7
1.0
1.1
0.4
0.4
0.6
0.6
0.5
1.5
0.8
2.6
0.5
0.8
0.6
3.2
3.1
1.20

YGR138C
1.1
1.6
1.0
1.2
0.8
0.8
0.7
1.0
0.5
1.0
0.7
0.6
0.6
0.9
4.5
0.7
0.7
0.7
1.24

YOR247W
1.7
0.6
3.6
1.4
0.6
0.2
0.5
0.7
0.1
0.4
2.9
0.6
0.3
0.4
7.3
0.2
1.2
0.9
2.23

YPL163C
0.6
0.7
1.4
0.9
0.6
0.6
0.4
0.5
0.1
0.4
0.5
0.9
0.4
0.6
5.3
0.6
1.4
1.4
1.05

YHL040C
1.6
4.4
1.5
0.4
1.1
7.3
4.0
1.5
1.1
11.3
1.7
2.0
2.0
1.1
3.4
1.0
1.4
1.0
0.69

YEL065W
0.3
3.8
1.2
0.4
1.4
2.3
4.3
0.9
0.1
4.9
0.6
1.7
0.8
0.4
2.2
2.6
0.7
0.6
2.10

YIR002C
0.8
1.1
0.5
0.6
1.2
2.2
1.3
1.2
1.7
1.4
0.8
1.3
1.2
1.1
1.1
1.4
1.1
1.2
0.58

YNL259C
1.6
4.5
1.1
1.2
1.1
3.9
3.8
1.5
1.6
2.1
1.6
0.7
1.1
1.4
0.7
1.7
2.6
2.4
1.22

YBR145W
1.5
0.7
2.8
0.9
1.1
11.5
58.8
1.0
0.1
1.1
1.1
1.0
2.0
2.2
1.2
3.6
1.7
2.0
2.17

YLR043C
1.4
1.4
2.0
1.8
2.0
1.4
2.6
1.1
2.8
2.5
1.4
0.8
2.0
2.1
0.5
1.8
1.5
2.2
2.12

YGR209C
1.6
3.1
3.5
1.5
1.9
1.9
1.7
1.6
2.4
6.3
3.1
0.9
1.4
5.0
1.3
1.9
1.3
2.4
3.17

YDL168W
2.3
2.0
2.1
0.9
1.2
1.4
1.1
1.7
8.2
4.7
1.9
0.6
1.3
1.6
1.2
1.1
0.9
0.8
1.08

YDR513W
2.2
2.5
2.3
2.6
0.9
2.1
1.6
1.6
4.6
3.1
2.0
0.9
1.8
2.0
1.3
3.8
1.3
3.2
3.10

YGR088W
1.3
1.2
7.7
2.4
1.0
1.3
0.8
0.8
1.5
3.2
3.9
1.1
1.2
1.3
0.7
5.6
0.9
2.0
0.75

YHR048W
2.5
1.4
1.4
1.7
1.0
0.8
0.8
1.9
4.5
2.7
2.0
0.9
1.1
1.7
0.9
1.4
0.7
0.9
0.26

YJL101C
2.1
1.9
2.1
1.2
1.4
1.0
1.0
1.3
3.1
3.6
2.7
0.7
1.0
1.0
0.5
1.3
0.9
1.0
1.13

YML116W
4.1
1.3
1.5
1.4
1.2
0.9
1.4
2.2
1.4
3.1
4.3
0.5
0.8
2.0
1.9
1.0
1.0
1.0
0.94

YMR038C
1.9
1.7
1.8
0.8
1.5
1.0
1.1
1.9
2.4
2.6
2.7
0.9
1.7
1.1
0.6
1.5
1.2
1.3
1.76

YBR244W
0.6
1.4
2.0
0.9
1.7
1.0
0.6
1.0
1.4
3.0
1.5
0.5
0.4
3.7
0.4
0.7
1.2
1.2
3.42

YCL069W
0.9
15.7
0.9
0.8
0.9

1.4
1.3
1.2
6.9
1.0
0.9
0.8
1.3
1.4
0.9
1.0
1.0
0.25

YKR105C
0.8
0.9
0.9
1.5
1.0
1.2
1.0
1.3
1.0
5.2
0.0
0.8
2.5
1.2
1.5
0.7
0.8
1.0
0.26

YOL158C
0.7
4.0
2.4
0.9
1.2
2.0
1.6
0.7
1.7
6.1
0.7
0.9
1.4
1.0
0.9
1.2
1.4
1.7
1.30

YDR256C
0.8
1.4
0.7
1.3
1.2
0.5
0.6
0.8
5.2
2.0
1.4
0.8
1.1
1.6
1.0
4.3
1.0
2.0
0.30

YGL254W
1.2
1.1
0.8
0.6
1.1
0.7
1.3
1.4
3.1
1.8
1.1
1.2
2.4
1.3
1.1
1.4
0.8
1.2
0.53

YKL064W
0.6
0.9
0.4
0.8
1.2
1.5
1.1
0.9
2.4
1.6
0.7
0.7
1.6
1.1
0.7
1.4
1.3
1.3
0.60

YLL057C
2.2
59.9
1.8
0.9
1.1
1.0
1.6
1.4
121.8
2.9
1.3
0.7
1.4
1.1
1.4
0.9
3.0
1.3
0.19

YPR200C
47.7
1.7
0.8
5.0
1.6
0.8
1.3
1.4
4.7
3.8
2.0
0.4
0.6
2.0
0.7
1.2
1.1
1.0
0.27

YJR104C
1.4
1.8
2.9
1.2
1.5
1.4
1.1
1.5
1.9
2.8
2.6
0.9
0.9
2.0
1.3
2.9
0.9
1.1
3.50

YKR106W
1.3
0.8
2.1
1.4
1.2
1.6
0.9
1.3
10.5
7.4
1.8
0.8
1.4
1.7

2.8
0.9
0.8
0.16

YOR031W
2.6
1.7
1.3
3.4
1.4
0.9
1.3
0.9
0.7
1.3
1.2
0.8
1.8
1.5
1.4
6.2
1.7
2.4
0.52

YHR008C
1.3
6.9
4.8
1.8
0.6
1.0
0.7
0.9
1.7
2.4
2.1
0.7
1.2
1.6
1.7
2.2
0.9
1.0
1.04

YML028W
1.0
2.2
4.4
1.3
1.6
1.2
0.8
0.8
0.8
1.8
1.0
1.6
1.6
2.0
2.2
1.3
1.1
1.5
4.85

YEL027W
1.2
0.6
3.4
1.1
1.0
1.1
0.8
0.9
0.9
1.1
0.9
0.9
0.7
1.4
1.5
1.6
1.0
1.4
4.75

YKR066C
0.9
1.4
5.5
0.7
1.0
0.9
0.5
0.7
0.7
2.4
1.3
0.9
0.6
1.5
0.6
1.3
0.9
1.1
1.25

YDR538W
0.9
1.1
2.4
1.2
1.0
1.0
1.2
1.0
0.3
0.8
0.9
0.7
0.7
0.9
1.0
0.9
1.0
0.9
0.53

YMR015C
0.7
0.7
1.9
0.9
1.7
1.3
0.4
0.7
0.1
0.3
1.0
0.9
0.4
0.8
1.2
1.5
1.0
1.0
2.51

YOR251C
1.1
1.0
1.3
1.8
0.8
0.9
1.0
1.1
0.8
0.8
1.0
0.9
1.0
1.1
0.6
1.2
0.9
1.3
1.34

YLR046C
0.7
1.7
0.9
0.8
1.0
3.8
1.5
0.5
1.0
1.4
0.9
0.8
1.2
1.3
0.8
1.3
5.2
5.4
0.86

YGR224W
0.9
1.2
1.2
1.2
1.4
0.8
0.4
0.6
0.9
0.9
0.8
0.6
0.8
0.9
1.1
1.0
2.8
1.3
0.27

YFL050C
0.7
1.0
1.1
2.2
1.0
0.9
0.8
0.9
0.5
1.6
1.2
0.9
1.2
1.0
1.4
2.3
0.8
1.0
0.36

YCR083W
1.1
2.8
1.5
1.8
1.6
2.4
1.8
1.5
1.8
1.8
1.8
1.1
1.8
2.4
1.0
3.1
1.3
1.3
0.98

TABLE 9

Genes belonging to other category

The level of expressed mRNA in the presence of chemical substance/

The level of expressed mRNA in the absence of chemical substance

yeast genes
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
(13)
(14)
(15)
(16)
(17)
(18)
Intensity

YKR076W
5.0
2.6
3.5
2.2
1.0
4.7
4.9
6.2
43.4
43.1
18.6
1.5
5.1
14.7
3.2
9.6
1.8
2.7
0.27

YNL335W
1.2
0.7
1.5
2.3
1.5
1.6
1.3
1.7
1.6
5.3
1.1
0.8
0.9
4.6
1.7
1.0
1.2
1.1
0.22

YBR173C
1.1
2.4
3.4
1.6
0.7
1.3
1.6
1.2
6.0
5.1
2.5
1.7
3.8
3.0
15.4
2.1
0.9
1.6
1.15

YFL022C
0.8
0.9
1.5
0.6
0.7
0.9
0.3
0.8
0.5
0.5
1.2
0.6
0.6
3.1
1.1
1.3
0.9
0.8
1.07

YGL158W
1.1
2.8
1.9
12.9
1.0
0.4
1.3
1.3
−0.4
0.9
0.2
1.3
1.0
2.3
2.3
8.2
0.8
1.1
0.18

YHR139C
3.0
4.6
6.8
9.3
1.3
1.9
1.5
1.3
107.2
46.6
3.5
1.6
7.0
2.5
1.9
17.1
1.4
1.3
0.34

YGR213C
5.4
2.9
1.0
6.8
1.2
4.1
7.0
2.0
7.5
6.9
1.6
10.6
30.4
1.0
6.5
5.2
12.8
8.5
0.22

YKL165C
0.5
2.0
1.1
0.6
0.9
0.6
2.1
1.5
0.4
0.4
0.3
2.4
3.2
0.8
2.1
1.2
0.9
1.0
1.08

YBL005W-A
1.0
0.9
0.5
0.9
1.3
1.2
1.4
1.0
0.8
1.5
0.8
1.6
2.9
1.4
0.9
1.1
1.3
1.0
0.48

YBL041W
1.2
1.4
0.9
1.0
1.6
1.7
1.6
1.7
2.8
2.6
1.6
1.6
2.6
2.0
1.3
2.3
1.3
2.0
3.03

YBL078C
2.3
2.7
1.3
2.6
0.7
2.4
3.1
1.6
12.3
15.2
4.6
3.1
5.0
3.6
2.5
4.4
1.8
2.8
0.65

YCL020W
1.1
2.5
0.5
1.1
0.5
1.0
1.5
1.7
0.9
2.4
1.3
1.5
3.0
1.7
2.5
1.3
0.9
1.3
1.46

YDL007W
0.8
1.4
1.3
0.9
1.0
1.1
1.2
1.4
3.8
2.4
1.3
1.1
2.4
1.4
1.4
0.8
0.8
1.5
2.43

YDL097C
0.9
1.7
0.9
1.2
0.8
1.3
1.6
1.5
4.5
2.3
1.5
1.3
4.0
1.4
1.1
1.1
1.0
1.3
2.06

YDL126C
0.5
1.4
2.3
0.7
0.9
1.2
1.5
0.8
2.7
2.0
1.4
1.3
4.3
0.6
1.7
0.7
0.9
0.9
3.24

YER012W
1.4
1.2
1.2
1.0
1.9
2.4
2.4
1.8
6.7
2.7
1.9
1.5
2.9
4.6
1.7
2.2
1.5
1.3
1.84

YFR010W
1.1
1.1
0.8
1.2
0.9
1.3
1.4
1.6
4.3
3.4
1.5
1.2
3.7
1.1
1.5
1.3
0.9
1.4
1.89

YFR024C
0.8
25.0
2.3
1.1
0.7
1.4
3.0
0.9
5.3
4.1
1.9
1.5
2.8
1.2
0.9
1.9
1.0
1.4
1.06

YGL048C
1.0
1.3
0.7
1.3
1.8
1.5
2.0
1.5
2.4
2.1
1.5
1.3
2.5
1.2
1.0
1.6
1.4
2.0
3.07

YGL141W
0.8
1.2
1.1
0.7
1.4
3.0
1.7
0.8
4.5
1.9
0.6
1.4
3.6
1.2
1.5
1.2
1.4
1.2
0.44

YGL180W
1.3
1.3
1.7
0.6
1.2
1.1
2.4
1.2
7.2
3.7
1.3
1.4
2.6
1.0
1.3
1.7
1.0
1.1
0.28

YGR048W
0.7
2.7
1.4
1.3
1.0
1.0
1.9
1.4
4.4
3.1
1.1
1.1
2.5
1.3
0.8
1.1
0.9
1.2
0.93

YGR135W
1.0
1.0
1.0
1.1
1.6
1.5
2.2
1.8
1.5
2.3
1.6
1.2
2.8
2.6
1.5
1.5
1.0
1.9
3.10

YGR201C
1.7
11.9
2.4
2.0
0.8
3.1
2.6
1.6
5.4
3.5
1.6
1.9
8.6
1.6
0.5
14.4
1.4
2.1
0.60

YHL030W
0.5
0.8
1.0
0.7
0.7
1.9
0.9
0.8
2.7
2.5
1.1
1.1
3.8
1.0
2.0
0.5
0.8
0.9
0.66

YHR166C
0.9
1.1
1.0
0.7
1.0
1.8
1.5
1.0
2.6
1.2
0.6
1.7
6.9
1.2
0.9
1.1
1.4
1.5
1.35

YJR069C
0.8
0.8
0.9
0.6
0.9
1.2
1.3
0.9
0.7
0.6
0.9
1.1
3.9
0.6
0.4
0.8
1.0
0.9
1.73

YKL073W
0.6
1.4
0.5
0.6
1.2
0.5
2.1
1.6
1.3
1.1
0.5
1.5
3.3
0.7
1.6
1.0
1.2
1.5
1.29

YKL103C
1.6
4.1
2.5
2.1
0.9
2.7
2.8
1.6
8.3
9.9
2.8
1.3
3.8
2.0
2.1
1.2
1.9
2.2
0.56

YLR080W
1.0
1.4
1.2
1.7
1.1
2.5
2.8
1.3
2.3
1.5
1.9
0.8
3.6
1.2
0.7
3.0
1.6
2.2
0.41

YLR107W
1.2
0.9
0.5
1.2
1.7
2.3
1.6
1.1
1.8
1.2
0.8
1.0
2.9
1.6
1.1
1.6
1.8
2.4
0.94

YLR121C
1.7
1.7
1.1
1.2
1.0
1.6

1.3
2.2
2.0
2.2
1.1
4.0
1.2
10.7
1.5
2.7
1.4
0.30

YLR336C
0.6
0.8
0.7
0.4
0.9
0.8
1.8
1.0
−0.3
0.5
0.5
1.9
4.6
0.6
0.8
1.3
1.5
1.0
0.71

YLR370C
1.1
1.0
1.1
1.4
1.4
4.1
2.1
0.8
1.5
1.9
1.0
1.2
3.1
1.9
1.5
1.6
1.6
2.0
1.41

YLR423C
1.2
1.2
0.7
1.9
1.5
1.2
3.8
2.0
1.2
1.0
1.0
1.7
3.9
1.2
1.3
1.9
1.2
1.6
0.34

YML092C
1.1
3.1
2.4
1.1
0.9
1.9
1.2
1.2
6.4
4.0
2.5
1.2
2.3
1.6
1.4
2.2
1.3
1.5
1.72

YML130C
1.5
2.7
5.3
1.2
0.9
0.6
2.9
2.7
7.8
4.2
1.9
2.3
5.8
1.3
2.4
0.8
1.2
1.2
1.59

YMR214W
0.8
3.8
1.0
1.4
0.8
0.9
1.0
1.1
2.1
1.0
0.7
1.0
2.4
1.1
4.8
0.7
1.1
1.0
0.88

YMR297W
0.7
2.0
3.6
1.9
0.6
1.8
1.2
0.8
1.9
1.0
2.5
1.2
4.2
0.5
2.4
1.9
1.1
1.4
4.10

YNL036W
2.0
1.9
3.2
1.0
1.6
1.1
2.0
2.1
6.6
5.0
1.7
1.4
3.3
5.1
1.6
1.3
1.4
1.9
2.04

YOL005C
1.4
1.4
1.1
0.8
1.6
1.1
1.1
1.0
0.9
1.0
1.6
1.2
2.9
1.2
0.9
1.0
1.2
1.2
1.71

YOR134W
2.0
3.6
1.0
9.5
0.9
1.4
1.1
1.5
1.5
8.2
1.9
2.8
4.4
1.3
1.6
7.7
2.2
4.6
0.28

YOR362C
1.0
1.7
1.0
0.8
1.7
1.4
1.6
1.4
4.3
3.0
1.3
1.3
2.5
1.4
1.0
1.5
1.1
1.8
2.55

YAR009C
0.8
1.3
0.6
1.0
1.4
1.6
2.7
1.4
0.9
1.4
0.9
1.3
2.0
1.0
2.1
0.6
0.8
1.2
7.11

YBL101C
1.0
1.1
1.9
0.9
1.0
0.9
0.8
0.8
3.0
1.4
0.8
1.1
3.5
0.9
2.7
1.4
1.0
1.1
0.39

YBR046C
1.4
1.4
1.7
1.8
1.3
2.6
3.9
1.6
4.6
6.2
2.9
1.2
2.0
1.3
2.1
3.0
1.2
2.0
0.63

YBR139W
1.2
1.4
3.1
1.4
0.8
2.4
1.9
0.7
2.3
1.6
2.3
1.2
2.7
1.1
5.6
2.3
1.2
2.0
1.21

YBR170C
0.8
1.2
0.6
1.4
1.5
1.4
1.9
1.3
6.1
4.2
1.5
1.2
2.7
1.3
1.9
1.3
1.1
1.4
0.72

YBR177C
0.8
1.1
4.0
1.2
1.2
2.3
0.9
0.9
2.1
1.7
0.6
1.2
3.1
1.3
1.4
0.4
0.8
0.9
0.76

YBR212W
0.7
1.2
2.6
1.2
1.0
1.4
0.9
0.6
2.7
2.3
1.1
0.9
2.2
0.7
1.0
1.5
1.1
1.0
0.95

YBR239C
1.0
1.3
0.9
1.5
0.8
1.5
1.0
1.3
0.4
1.2
0.7
1.1
1.9
1.1
1.0
2.7
1.0
0.9
0.31

YCL033C
1.1
2.0
1.7
1.7
1.2
4.6
2.4
1.1
2.3
1.4
1.9
1.6
2.0
1.8
0.8
3.6
2.0
2.0
1.14

YCR062W
0.8
1.9
2.7
2.8
1.4
1.9
0.9
0.7
0.7
1.3
1.2
1.3
2.2
1.0
2.3
1.1
1.1
1.0
0.41

YCR067C
0.9
0.7
1.2
1.3
0.7
0.8
0.8
0.7
1.8
1.6
1.2
0.9
2.0
0.9
2.1
1.4
1.1
0.9
0.62

YDL020C
2.3
1.2
3.4
1.1
1.2
2.5
1.0
2.2
5.6
2.9
1.9
1.1
3.4
1.2
1.5
1.8
1.5
1.7
1.36

YDR168W
1.2
1.4
1.0
0.8
1.5
1.3
2.4
2.1
3.7
2.3
1.5
1.2
2.4
1.4
1.9
1.4
1.2
1.4
1.28

YDR169C
1.0
1.4
1.1
1.3
1.3
1.2
1.1
1.0
1.6
1.4
0.9
0.9
1.9
0.9
1.4
0.9
1.4
1.1
0.40

YDR188W
0.8
1.2
1.0
0.8
0.8
0.8
0.9
1.0
2.9
1.6
0.9
0.9
1.7
0.7
1.3
0.9
0.7
0.8
1.78

YDR264C
0.5
2.6
0.9
1.4
0.9
1.8
3.2
0.8
1.1
3.4
0.9
1.1
2.1
0.7
2.3
1.5
1.2
1.4
1.63

YDR304C
1.0
1.8
2.7
1.3
1.5
2.1
2.0
1.3
3.9
1.9
1.2
1.3
2.3
1.7
1.0
4.0
1.6
1.8
2.23

YDR403W
1.0
1.2
1.6
1.0
1.2
1.1
1.2
1.2
4.1
3.6
1.0
1.0
2.0
1.1
0.9
0.9
0.9
1.0
0.35

YDR427W
0.8
1.1
0.8
0.8
1.5
1.9
1.4
1.2
2.3
2.0
1.2
1.1
2.1
1.0
1.3
1.1
1.0
1.5
2.37

YEL012W
1.3
1.8
1.0
1.8
1.7
1.6
4.7
1.4
4.6
4.2
2.2
1.2
2.2
1.9
1.1
2.5
1.5
2.2
0.74

YER009W
1.3
0.6
2.4
1.2
1.2
2.0
2.8
1.0
0.7
1.0
1.4
1.1
2.0
1.6
0.9
1.5
2.0
2.1
3.35

YER021W
0.8
1.0
0.9
0.9
1.4
1.1
1.5
1.2
3.0
2.2
1.3
1.0
1.8
1.3
0.8
1.4
0.8
1.5
2.02

YER094C
1.0
1.3
0.9
1.1
1.9
1.1
1.8
1.3
2.3
1.7
1.3
1.1
2.1
1.5
0.8
1.5
1.3
1.8
3.01

YER177W
1.4
1.5
2.1
1.5
0.9
1.6
1.2
1.1
1.8
1.7
1.9
1.1
2.2
0.9
1.4
1.0
0.9
2.0
5.81

YFL029C
1.0
1.2
1.2
1.8
1.7
1.0
1.6
1.5
4.3
2.9
2.1
1.1
1.8
1.9
1.3
1.2
1.2
1.4
0.49

YFL038C
1.0
1.2
0.7
1.3
1.5
1.3
1.7
1.4
2.1
1.9
1.7
1.1
2.1
1.5
1.5
2.1
1.2
1.6
2.31

YFR004W
1.0
1.5
0.8
1.4
1.0
1.5
1.3
1.4
3.6
2.6
1.3
1.2
2.0
2.1
1.1
1.3
1.0
1.4
2.44

YFR050C
0.9
1.2
1.1
1.3
1.7
1.5
1.4
1.4
3.1
2.1
1.4
1.5
2.1
1.6
1.5
1.5
1.1
1.7
1.70

YGL011C
1.2
1.5
1.1
1.1
1.8
1.6
1.5
1.3
2.0
2.2
1.5
1.0
2.1
3.0
1.3
1.7
1.3
1.5
1.78

YGL094C
0.8
1.3
0.3
0.9
1.3
1.0
0.8
1.0
1.4
1.1
0.6
0.8
2.3
0.9
1.9
1.0
1.0
0.9
0.51

YGL150C
0.7
0.8
1.2
1.0
0.8
1.1
0.8
0.8
1.4
0.9
0.4
0.8
2.4
1.0
1.3
0.9
0.9
0.8
0.62

YGL207W
0.5
0.6
0.9
0.6
1.3
0.9
0.6
1.0
1.4
1.1
0.7
0.7
2.5
0.8
1.2
0.7
0.9
0.8
0.88

YGR232W
1.2
1.2
1.2
1.7
1.5
1.9
2.0
1.1
3.4
2.2
1.3
1.1
2.4
2.1
0.9
1.8
1.3
1.2
0.96

YGR248W
1.3
1.7
3.2
4.0
0.5
2.3
1.1
1.2
2.8
3.2
2.3
1.1
2.0
1.5
1.5
7.9
1.0
1.5
0.52

YGR253C
1.3
1.4
0.7
1.3
2.0
1.4
1.6
2.0
4.0
3.1
2.4
1.1
3.4
1.8
1.1
1.8
1.5
2.1
2.01

YHR027C
0.5
0.8
1.2
0.6
1.1
0.4
0.9
0.6
3.6
2.2
1.1
1.0
2.1
0.7
1.5
0.9
0.8
1.0
2.06

YHR161C
0.6
1.1
1.3
2.1
1.5
1.2
1.8
0.7
2.5
2.0
1.2
1.0
1.8
1.0
1.4
1.7
1.4
1.5
0.86

YHR169W
0.6
0.5
0.4
0.4
1.1
1.2
0.9
0.9
0.0
0.2
0.4
1.1
3.3
1.1
0.6
1.0
1.6
1.3
0.81

YIL010W
1.0
1.2
1.4
0.8
1.2
4.4
1.5
0.9
1.4
2.2
1.4
1.4
2.3
1.7
1.1
1.7
1.5
1.5
0.70

YIL034C
1.0
0.8
1.5
3.0
0.7
1.7
1.2
0.9
2.1
1.3
1.6
1.0
2.6
1.1
1.0
1.7
1.2
1.5
0.99

YIL142W
0.7
1.1
0.9
1.1
0.8
1.1
0.8
1.1
4.4
3.0
1.7
1.1
1.8
1.0
1.3
0.7
0.9
0.8
1.84

YIR039C
1.4
1.8
4.3
4.2
1.5
3.2
4.1
1.1
4.4
4.1
3.8
1.4
2.9
1.9
2.0
4.2
1.2
1.1
0.45

YJL001W
0.9
1.7
1.2
2.0

1.7
1.6
1.3
3.1
2.8
1.5
1.6
2.9
2.5
1.2
1.8
1.0
1.6
3.00

YJL035C
0.9
1.3
0.8
0.6
1.4
0.7
1.3
1.5
1.7
1.4
0.8
1.1
2.4
1.6
0.7
0.6
1.0
1.0
0.82

YJL053W
1.1
0.9
1.7
1.3
1.1
2.0
1.7
1.3
2.2
2.2
1.6
1.1
1.9
1.3
1.1
1.7
1.3
1.6
0.80

YJL164C
1.1
1.1
1.0
1.9
1.1
2.7
3.1
0.9
2.1
0.8
1.5
1.0
2.1
0.9
0.8
2.1
1.3
1.7
1.04

YJL210W
1.2
1.4
1.6
2.0
0.6
0.6
1.0
1.0
2.0
0.9
2.4
1.0
2.2
0.9
0.8
2.3
0.9
1.0
0.70

YJR117W
1.0
2.1
2.3
0.7
1.2
1.3
1.0
0.8
4.7
2.3
1.0
1.2
2.8
0.8
2.2
0.7
0.8
0.9
1.34

YKL007W
1.2
1.6
1.2
0.9
1.0
0.9
1.5
1.2
2.3
2.4
1.8
1.3
2.5
0.7
1.0
1.0
1.4
1.3
1.13

YKL117W
1.0
1.3
0.8
1.0
1.8
1.0
1.3
1.5
2.9
2.1
1.6
1.0
2.4
1.6
1.6
1.8
1.2
1.8
3.73

YKL193C
1.3
0.8
1.1
1.4
1.1
0.9
2.1
1.4
1.0
1.6
1.7
0.9
2.1
1.2
1.2
2.4
1.2
2.3
0.71

YLR120C
1.2
1.9
2.4
1.6
1.1
1.9
1.5
0.9
1.8
1.6
1.2
1.6
4.8
0.8
2.7
1.7
3.5
2.9
1.53

YLR136C
1.3
9.0
0.6
3.3
1.6
1.7
3.9
1.1
0.9
6.0
1.2
1.3
2.9
0.7
2.1
1.2
1.8
1.4
0.41

YLR178C
1.7
6.9
8.8
4.6
1.0
4.2
3.3
0.9
4.3
4.1
3.7
2.2
7.5
2.8
2.3
10.6
2.0
3.6
1.03

YLR327C
5.5
3.3
14.4
8.2
1.3
5.1
5.7
2.2
3.0
8.3
5.0
1.4
2.8
1.5
0.8
2.8
3.3
5.3
2.23

YLR356W
1.0
2.9
4.9
1.2
1.1
3.4
1.1
0.7
2.3
1.6
3.1
1.5
2.5
2.2
2.8
0.9
1.1
1.0
0.41

YLR362W
1.1
1.2
1.0
3.0
1.5
0.8
1.9
1.4
3.5
3.3
1.5
0.8
2.4
1.2
1.3
1.9
1.2
1.3
0.35

YLR429W
0.7
1.0
0.6
0.9
1.4
0.8
1.3
1.0
0.9
1.3
0.9
1.1
2.3
0.7
1.5
1.0
1.0
0.9
0.86

YMR004W
0.9
0.9
1.3
1.3
1.0
0.5
1.2
1.0
94.2
3.4
2.5
1.0
2.2
2.2
1.3
1.3
0.9
1.3
0.52

YMR219W
0.7
1.1
1.0
0.7
1.6
0.8

1.1
2.3
0.9
1.5
1.5
2.1
0.5
1.7
0.8
1.1
0.9
0.23

YMR275C
0.7
0.7
1.2
0.6
0.7
1.4
0.8
0.8
2.4
2.1
1.1
0.7
2.1
0.8
1.7
1.0
0.9
0.7
0.79

YMR314W

1.2
0.9
1.3

1.3
1.1
1.2
5.9
2.7
1.8
1.0
2.6
1.0
1.2
1.6
1.3
1.6
1.67

YNL006W
1.1
2.1
1.3
1.5
0.9
1.0
1.6
1.1
4.0
4.0
1.1
0.7
2.3
0.8
0.7
0.9
1.0
1.3
1.20

YNL007C
0.7
2.4
5.1
0.8
1.2
0.6
1.2
0.8
3.0
1.7
1.3
0.7
2.1
0.4
0.8
0.5
1.1
1.0
3.62

YNL093W
2.1
6.4
0.4
4.5
1.2
1.6
1.4
0.8
1.7
2.0
1.6
1.1
2.2
1.1
0.6
4.9
3.0
3.1
0.32

YNL333W
1.0
1.4
1.7
2.3
1.5
1.5
2.9
2.1
2.3
2.1
2.0
1.0
2.2
1.9
1.0
1.4
1.4
1.1
0.49

YNR010W
1.3
1.2
0.5
2.8
1.8
1.3
1.5
1.1
1.7
0.9
1.4
0.8
2.8
1.3
0.8
1.2
1.7
2.3
0.37

YNR069C
1.5
1.3
0.7
0.4
1.4
1.7
1.4
1.4
5.5
5.8
2.5
1.2
3.4
2.1
1.0
0.8
1.1
0.9
0.18

YOL164W
0.9
4.4
1.0
1.5
1.6
1.2
2.2
1.0
4.9
3.6
1.0
1.1
3.4
1.3
1.0
1.1
1.1
1.3
0.45

YOR036W
1.8
0.9
1.4
1.6
1.1
1.7
1.8
1.4
1.2
1.9
1.3
1.2
2.1
1.2
1.2
1.3
1.6
1.7
0.98

YOR117W
0.8
1.3
1.7
0.8
1.2
1.1
3.3
1.0
3.5
1.8
1.2
2.5
2.3
1.0
1.4
1.2
1.4
0.9
1.42

YOR124C
0.6
1.1
1.3
0.8
1.1
0.9
1.1
1.3
2.0
1.9
1.2
0.9
2.1
0.8
1.3
0.9
1.0
1.0
0.65

YOR132W
0.9
1.6
0.8
2.8
1.1
1.6
1.4
1.2
2.8
1.6
1.3
0.7
2.5
0.7
1.5
1.6
1.2
1.6
0.46

YOR157C
1.0
1.3
1.2
1.3
0.7
1.2
1.2
1.2
5.7
2.6
1.6
1.3
2.4
2.2
1.9
0.9
1.2
1.2
1.23

YOR185C
1.1
1.3
1.9
1.1
1.2
3.0
1.3
1.4
1.9
2.9
1.2
1.5
2.2
2.1
1.0
2.2
0.9
1.1
1.67

YOR259C
0.8
1.1
0.8
0.9
2.0
0.8
1.3
1.1
2.7
1.5
1.0
0.8
1.8
1.2
1.3
1.4
0.9
1.5
2.33

YOR261C
1.0
1.4
0.6
0.9
1.5
1.4
1.9
2.6
5.5
2.5
2.1
0.9
2.5
1.8
1.3
2.0
1.0
1.9
2.80

YOR288C
0.9
1.3
1.1
1.1
1.1
1.0
2.0
1.9
0.9
1.0
1.4
1.4
2.4
0.8
1.8
1.4
1.5
1.6
0.79

YPL109C
1.1
2.5
0.5
1.2
1.2
1.2
1.8
1.1
1.2
1.5
−0.2
0.9
1.8
1.3
1.3
1.9
1.2
1.2
0.21

YPL149W
1.5
1.5
0.6
2.8
0.8
0.9
1.2
1.1
5.6
3.7
1.2
0.9
2.3
1.0
0.8
1.2
2.2
2.9
1.39

YPL154C
0.7
3.3
4.2
1.2
1.2
3.5
1.5
0.8
2.8
1.7
1.8
1.5
3.1
0.8
4.0
1.8
1.6
2.0
3.78

YPR103W
0.7
1.1
1.3
0.7
1.7
1.2
1.6
1.0
5.5
2.0
0.9
1.2
2.8
1.8
1.0
1.1
1.2
1.5
1.93

YPR108W
0.8
1.0
1.3
0.6
1.3
1.5
1.6
1.6
3.7
2.8
1.8
1.0
2.6
1.0
1.3
1.2
1.0
1.3
2.25

YCL027W
0.7
2.0
1.0
1.0
1.2
1.3
1.0
0.6
0.7
16.3
0.9
0.8
1.1
1.2
3.6
1.1
0.7
0.8
0.30

YDR055W
1.7
2.1
2.2
2.8
1.7
3.9
1.5
1.6
0.8
2.4
2.2
1.4
3.1
0.9
5.7
3.4
2.0
1.9
1.55

YEL042W
0.6
0.9
1.7
0.9
0.7
0.5
0.5
0.7
0.2
0.3
1.6
1.0
0.4
0.6
4.8
0.6
0.7
0.8
1.21

YGR136W
0.9
1.2
1.3
0.7
1.2
1.1
1.5
1.3
2.1
2.2
1.3
1.2
1.7
1.1
2.6
2.2
1.3
1.8
1.42

YHR142W
1.5
0.8
2.1
0.8
1.3
1.2
0.9
1.3
0.4
0.9
1.1
1.3
1.2
1.2
4.8
1.0
1.3
1.3
1.17

YJL073W
0.8
0.8
2.5
0.7
1.2
2.0

1.0
1.7
0.7
0.5
1.0
1.6
1.1
2.6
0.8
1.1
1.0
0.43

YJR004C
0.2
0.8
3.4
0.6
1.1
1.2
0.4
0.4
0.3
0.7
0.7
0.8
0.3
0.7
3.2
0.3
0.4
0.4
2.12

YKL039W
0.8
1.1
2.4
0.8
0.7
4.9
2.0
0.8
1.3
3.3
1.0
0.9
1.9
0.8
3.1
1.5
1.2
1.3
1.13

YLR250W
1.5
1.0
1.0
1.4
1.4
1.1
1.9
1.3
2.7
2.4
1.4
1.0
1.2
2.5
2.6
2.1
1.4
2.2
2.90

YOR181W
1.0
0.9
1.1
1.4
0.7
0.9
0.7
0.7
0.6
0.5
1.0
0.8
1.2
0.9
3.4
1.0
1.1
0.6
0.39

YOR198C
1.0
0.7
1.4
1.0
0.8
0.9
1.6
1.3
2.4
1.4
1.4
1.5
1.8
1.1
3.8
0.8
1.1
1.5
1.76

YPL089C
1.2
1.0
0.5
1.8
1.4
0.8
0.9
0.8
0.4
2.5
0.9
0.7
1.3
0.8
2.6
0.9
1.5
1.1
0.37

YBR214W
0.9
2.1
5.7
2.0
1.1
0.8
1.1
0.7
2.2
3.5
3.2
1.2
2.1
0.9
5.1
1.3
1.1
1.2
0.51

YDR085C
1.9
1.8
1.6
3.4
0.9
2.1
4.1
2.0
0.4
2.3
1.7
1.6
1.1
1.6
3.1
2.3
1.3
1.8
0.37

YDR259C
1.4
1.0
0.4
1.4
1.0
0.5
2.8
1.4
1.0
1.8
1.2
1.0
2.0
1.5
2.9
0.9
1.0
0.8
0.28

YDR388W
0.7
0.7
1.2
1.0
0.7
1.0
1.1
0.8
1.4
0.9
1.6
0.8
1.7
0.6
2.6
1.0
1.2
1.3
0.99

YDR432W
0.5
0.8
1.0
1.4
1.6
0.6
0.5
0.5
0.7
0.8
0.6
0.7
1.4
0.5
2.6
0.6
0.7
0.7
2.38

YDR481C
0.7
2.3
1.3
0.7
1.0
0.9
0.7
1.0
1.9
1.6
1.2
0.9
1.5
0.9
3.5
1.3
1.2
1.4
1.43

YDR510W
1.0
1.3
1.5
1.3
0.7
1.0
1.6
1.5
2.7
2.5
1.6
1.4
2.0
1.9
2.2
1.5
1.1
1.5
1.57

YGR189C
1.1
0.9
1.5
3.5
0.7
0.5
0.6
1.0
0.3
0.9
1.5
1.3
1.2
0.9
9.3
0.6
2.3
1.7
1.51

YIL123W
1.0
0.5
1.2
1.5
0.6
0.5
0.5
0.6
0.1
0.2
1.2
0.8
0.4
0.3
4.8
0.7
1.3
1.0
1.67

YIL140W
0.7
1.0
1.5
1.4
0.8
0.5
0.5
0.7
0.7
0.6
0.9
1.0
0.5
0.9
3.3
0.6
0.7
1.0
0.62

YKL096W
1.4
0.6
8.1
1.6
0.6
0.6
0.2
0.5
0.0
0.5
3.5
0.3
0.1
0.5
2.3
0.4
0.5
0.7
2.04

YLR391W

0.7
2.9
0.8
1.2
1.5
0.7
0.7
0.4
0.7
1.4
1.0
0.9
0.5
3.9
1.3
1.4
0.9
1.72

YMR094W
1.0
0.5
1.3
1.7
0.9
0.5
0.8
1.0
−0.1
0.9
1.0
0.9
1.4
2.8
6.6
1.0
1.0
1.0
0.23

YMR104C
1.9
14.3
2.2
2.6
0.7
1.9
1.5
0.9
0.6
3.2
1.1
1.0
1.5
1.1
2.5
2.3
2.8
1.9
0.51

YMR276W
0.6
1.4
1.5
0.7
1.3
0.8
1.1
0.8
1.8
1.7
1.9
1.2
1.9
1.2
3.3
0.9
1.2
0.7
0.47

YOL013C
0.9
1.0
1.0
1.5
0.7
1.1
1.7
1.0
0.8
1.0
1.4
1.1
1.8
0.9
2.7
1.3
1.1
1.4
0.65

YOR355W
0.7
0.6
1.1
0.8
1.0
1.6
1.1
0.8
0.1
0.8
1.2
0.9
1.1
0.6
3.2
0.8
0.8
0.9
0.98

YCR071C
1.1
0.7
0.9
0.8
1.2
2.5
1.4
0.9
0.6
1.2
1.1
1.1
1.3
1.7
1.1
1.5
1.2
1.3
0.96

YDL008W
1.1
1.0
1.0
1.1
1.8
2.7
2.0
1.2
2.3
3.0
0.9
1.2
2.0
2.2
0.7
1.3
1.5
1.6
0.95

YDR115W
1.3
0.9
0.6
1.5
1.4
2.3
1.6
1.3
1.1
1.0
1.2
0.9
1.1
1.5
0.8
2.2
1.2
1.4
1.50

YER130C
0.9
1.6
0.5
0.8
1.7
2.7
1.5
1.2
0.5
1.3
0.9
1.0
1.6
0.8
1.1
0.7
3.0
2.5
1.36

YMR226C
1.1
1.8
1.4
1.6
0.9
2.6
1.8
1.6
2.6
2.2
1.4
1.1
1.6
1.6
2.0
1.7
1.6
2.0
2.03

YOR383C
0.9
4.3
2.6
0.9
0.9
6.8
8.0
1.0
1.2
4.5
1.4
1.1
1.2
0.6
1.1
3.0
1.4
1.1
0.68

YAR010C
0.8
1.2
1.2
0.8
1.0
2.3
1.9
1.3
1.2
1.1
0.9
1.0
1.4
1.0
1.8
0.7
1.5
1.0
4.69

YBL043W
1.2
1.2
1.1
1.3
1.1
26.9
1.5
2.1
0.5
14.7
1.5
0.9
1.8
1.9
1.8
2.3
2.3
1.8
0.47

YCR004C
1.7
1.0
12.0

1.2
1.8
1.4
1.2
4.7
2.1
1.9
0.8
1.3
3.7
0.8
4.9
1.4
3.5
3.02

YCR088W
0.9
1.1
1.2
0.9
1.1
2.0
1.2
0.5
0.8
0.9
1.0
1.3
1.9
0.9
2.8
0.7
1.4
0.9
0.47

YDL238C
0.7
1.0
1.1
1.7
0.9
2.1
1.4
5.8
1.7
2.7
1.1
0.9
2.0
1.2
1.3
1.7
1.1
1.3
0.35

YDR084C
0.9
0.9
1.5
1.1
1.2
2.1
0.9
0.7
0.6
0.6
0.7
0.7
1.0
1.0
3.9
1.0
2.0
1.3
1.12

YDR104C
0.8
1.1
1.2
1.2
1.3
1.7
1.0
1.3
2.8
2.7
1.0
1.1
1.6
1.4
1.4
0.9
0.9
1.0
0.34

YDR315C
1.0
1.4
1.0
1.3
0.9
9.4
1.4
1.4
1.1
1.6
1.1
0.6
1.6
1.4
1.5
1.5
1.2
1.2
0.48

YDR358W
0.7
1.1
0.7
1.1
1.4
2.5
2.8
1.2
2.9
3.2
1.0
1.1
3.2
1.2
0.9
2.2
1.9
1.9
0.50

YEL066W
2.0
2.9
1.5
2.2
0.8
2.2
1.8
1.4
1.3
2.4
1.9
0.8
1.6
1.9
1.0
1.9
1.0
1.1
0.64

YER039C
1.0
1.2
1.0
4.1
1.5
1.6
1.3
0.7
1.2
0.8
1.2
0.9
2.1
1.2
1.2
1.8
1.7
1.1
0.42

YER107C
0.9
0.5
1.0
0.6
1.3
2.5
1.0
0.8
0.4
0.5
0.7
0.7
0.9
1.1
0.7
0.9
1.1
1.2
0.92

YFL028C
1.2
1.1
0.7
1.5
1.7
1.7
2.0
1.5
2.7
1.8
1.3
1.1
1.4
1.6
0.8
1.9
1.2
1.5
1.28

YFL043C
1.0
1.2
0.6
1.2
1.2
1.8
1.8
1.0
2.2
3.8
1.1
0.9
1.5
1.5
1.1
2.0
1.5
1.2
0.38

YGL229C
0.6
0.7
0.9
0.8
1.0
2.2
2.2
0.7
1.8
1.7
1.1
1.1
1.7
1.0
0.2
1.8
1.1
0.9
0.44

YGR257C
0.7
0.8
0.9
1.1
1.3
2.1
2.4
1.0
1.5
1.9
1.2
0.9
2.0
0.9
1.3
1.3
1.1
1.3
0.84

YHR004C
0.9
1.1
0.8
1.1
1.5
2.0
1.5
0.9
1.1
0.6
0.8
0.9
1.1
0.8
1.2
2.4
1.4
1.6
0.84

YHR071W
1.5
1.1
0.6
1.6
1.5
2.0
1.0
1.7
1.0
7.2
1.8
0.8
2.3
1.6
3.0
1.7
2.6
1.0
0.79

YJL089W
1.1
1.5
1.0
0.8
1.1
1.6
1.1
1.1
1.6
3.9
0.6
1.2
1.8
1.8
6.4
1.2
1.2
1.1
0.21

YJL116C
0.9
1.8
1.3
1.9
1.3
3.4
0.8
1.8
2.4
2.6
2.9
1.1
4.3
2.6
1.0
1.3
1.2
0.7
1.01

YJR086W
1.2
1.1
0.8
1.4
1.3
1.9
1.7
1.1
1.4
1.1
1.0
0.8
0.9
2.2
2.0
1.4
1.4
1.6
1.24

YKL008C
1.2
0.6
2.0
0.8
0.9
3.8
1.4
1.2
0.3
0.4
1.5
1.5
1.7
0.8
1.3
2.1
1.4
1.9
2.11

YKL013C
1.4
0.9
1.4
1.1
1.9
1.9
1.8
0.9
1.5
1.4
1.1
0.7
1.3
1.4
1.2
1.5
1.6
1.7
1.55

YKL041W
1.2
0.8
1.1
1.0
1.3
2.2
1.0
1.6
1.6
1.5
1.2
0.8
1.3
1.3
1.0
2.5
1.1
1.3
0.91

YKL139W
0.9
0.7
1.4
0.8
2.8
3.5
2.6
1.2
1.6
1.5
1.4
0.8
1.6
1.0
1.0
1.3
1.9
0.8
0.62

YKR014C
1.1
1.3
0.7
1.1
1.5
2.1
1.7
1.6
2.4
2.0
1.1
1.1
1.5
1.8
1.4
2.4
1.0
1.7
2.05

YLR093C
1.3
0.8
0.7
1.2
1.4
2.9
1.9
1.2
1.5
1.3
1.0
1.0
1.3
1.3
0.9
2.4
1.7
3.2
1.90

YLR118C
1.0
1.1
1.6
1.0
1.0
2.5
1.5
1.0
1.1
1.3
1.2
1.0
1.4
1.5
0.8
3.5
1.3
1.9
1.17

YLR251W
1.8
0.8
4.2
4.6
1.6
2.1
2.6
1.2
2.1
1.3
4.1
0.8
1.7
1.3
0.8
2.5
2.1
3.8
0.78

YMR027W
0.8
2.6
0.7
0.8
1.1
2.1
2.0
0.9
1.1
1.4
1.1
0.9
2.4
0.9
4.0
0.8
1.3
1.2
4.05

YMR262W
1.0
1.3
1.9
1.1
1.2
2.0
1.9
1.0
3.0
1.2
1.3
0.8
1.7
0.9
0.3
1.0
1.0
1.2
0.65

YNL214W
1.2
0.9
1.1
1.1
1.4
2.3
1.3
1.1
1.5
1.5
0.6
0.8
1.2
1.7
0.9
2.0
1.1
1.2
0.47

YOR149C
0.7
0.9
1.0
0.8
1.1
2.3
1.0
0.7
0.4
1.0
1.0
0.9
1.3
0.9
1.3
1.1
1.0
1.2
0.76

YOR165W
0.9
1.5
0.7
0.8
0.8
2.2
0.9
1.1
0.8
1.3
1.3
0.7
0.9
0.8
0.8
1.0
0.9
1.0
1.03

YOR285W
1.4
6.0
3.5
1.9
1.7
2.1
4.0
1.2
4.0
2.9
2.3
0.9
2.1
1.6
2.0
2.9
2.3
3.3
2.62

YOR367W
1.0
0.9
1.7
0.9
1.1
3.3
1.9
1.1
1.1
1.1
1.4
0.5
0.8
1.5
1.1
1.3
1.4
1.4
0.60

YPL018W
1.0
1.4
1.0
0.5
1.8
2.1
0.9
1.1
1.4
1.2
1.3
1.1
2.2
1.3
0.9
0.8
1.3
0.8
0.22

YPL203W
1.3
1.0
2.2
1.0
2.1
1.8
2.1
1.1
1.8
2.1
1.5
0.9
1.5
1.0
0.6
2.3
1.3
1.7
0.79

YPL255W
0.8
0.3
1.1
0.6
0.9
2.0
0.6
0.9
0.1
0.1
0.7
0.6
0.6
0.7
0.6
0.7
0.8
0.7
0.55

YPR073C
1.2
1.9
0.5
1.4
1.8
2.0
2.5
1.5
1.3
2.6
0.9
0.8
1.4
1.5
0.8
1.8
1.4
1.8
1.55

YDR518W
0.8
1.7
1.1
1.2
1.6
1.2
2.7
1.1
0.2
1.2
1.0
1.5
1.8
0.8
2.5
1.7
1.4
1.6
0.93

YOR381W
0.8
2.0
0.8
1.8
1.0
1.0
3.6
0.8
1.2
3.5
2.6
1.1
1.7
0.8
0.6
2.5
0.8
0.9
0.38

YBR109C
1.6
1.3
2.4
1.1
1.0
1.4
2.4
1.7
3.8
3.3
1.5
1.4
2.0
2.0
1.4
1.9
1.4
1.9
2.15

YBR201W
1.2
4.3
1.2
2.4
1.2
1.0
3.4
2.2
0.8
1.0
1.1
1.7
1.9
1.1
1.6
1.5
1.8
1.6
0.75

YDR041W
1.2
1.1
0.6
1.8
2.0
1.6
2.4
1.2
1.3
1.3
1.2
0.8
0.9
1.4
1.0
2.4
1.5
2.5
1.85

YER136W
0.9
1.1
1.1
1.4
1.6
1.3
2.1
1.3
1.4
1.6
1.7
0.9
1.3
0.8
1.2
1.6
1.3
1.7
2.31

YER159C
1.1
0.9
0.2
1.6
2.1
1.3
2.0
1.4
0.2
0.9
1.6
0.9
0.9
1.1
2.2
1.1
1.6
1.9
0.99

YJL030W
1.6
1.4
0.5
1.0
1.3
1.1
1.9
1.6
2.3
1.9
1.4
1.0
1.4
2.1
1.5
1.9
1.3
1.5
0.87

YJR029W
0.8
1.3
0.6
0.8

1.0
2.4
0.9
1.1
1.5
0.6
1.0
2.1
1.1
1.8
0.7
0.8
1.1
5.84

YJR099W
1.4
0.9
1.1
1.3
1.5
2.1
2.0
1.4
1.4
2.4
1.3
0.7
1.5
2.1
0.5
2.0
1.1
1.7
0.94

YJR122W
2.0
1.4
2.5
1.1
1.3
1.4
1.8
1.4
5.3
6.1
2.4
0.9
1.3
1.4
0.8
1.9
1.0
1.1
0.43

YJR125C
1.0
1.0
1.2
1.0
1.2
1.3
1.9
0.9
1.8
1.3
1.1
0.9
1.5
1.1
1.3
2.0
1.2
1.4
0.90

YKL190W
1.1
1.3
0.4
0.9

1.5
2.0
1.1
1.8
1.9
1.5
0.9
1.3
1.7
1.4
1.8
1.3
1.3
1.14

YLL051C
0.8
1.1
1.0
1.5
1.4
1.2
2.0
0.9
0.9
1.8
0.7
1.1
1.3
0.8
1.2
0.8
1.0
1.0
0.81

YLR090W
0.7
1.1
0.8
1.3
1.2
1.3
2.2
0.9
1.8
1.4
1.0
0.8
1.7
1.0
0.8
1.9
0.8
1.0
0.67

YMR051C
0.9
2.8
0.8
1.3
1.7
1.2
2.6
0.9
1.0
1.4
1.1
0.9
1.3
1.2
1.7
1.0
1.8
1.2
3.91

YMR139W
1.0
3.4
2.5
1.5
1.2
1.5
2.2
0.9
2.8
2.4
1.3
0.9
1.6
1.3
0.9
2.3
1.1
2.0
0.89

YNL015W
2.3
6.7
1.8
2.4
1.8
1.7
3.5
2.2
2.1
4.3
2.1
2.8
3.9
1.6
1.4
5.3
3.0
5.2
1.03

YNL079C
1.1
1.0
0.4
1.0
1.7
1.1
1.9
1.6
1.5
1.2
1.3
1.2
1.8
1.0
1.5
1.4
1.0
1.9
3.26

YNL223W
1.1
1.2
0.6
1.7
1.0
1.8
2.2
1.4
3.3
1.9
1.3
1.3
2.0
1.2
1.0
2.1
1.0
1.5
0.34

YNR007C
1.2
1.8
0.7
1.0
1.5
1.3
1.9
1.2
2.5
2.0
0.7
0.9
1.5
1.5
0.6
2.0
1.4
1.6
0.49

YNR035C
0.8
1.2
1.7
1.0
0.8
1.1
2.6
1.1
2.9
1.5
1.5
1.1
1.7
1.0
1.3
1.6
1.4
1.8
1.60

YOL016C
1.3
2.0
0.4
2.0
1.6
0.9
3.0
1.3
1.9
1.6
1.3
1.4
3.0
0.7
0.5
1.6
4.3
3.8
2.10

YOL104C
1.0
1.7
0.2
1.8
1.9
1.4
2.6
1.4
0.2
1.7
1.2
0.8
0.6
2.2
1.3
0.5
1.1
0.9
0.32

YPR107C
1.4
1.0
1.2
1.9
1.5
1.3
2.0
1.3
2.4
2.4
1.2
0.7
1.4
1.7
1.0
1.4
1.2
1.5
0.81

YOL152W
0.2
0.6
1.0
0.8
0.7
1.8
2.4
4.1
0.9
1.2
5.9
0.8
0.5
0.4
0.8
1.2
1.1
1.2
0.91

YAL007C
1.3
0.9
0.9
1.5
0.6
0.7
1.5
1.7
1.1
0.9
2.0
1.3
2.0
1.3
2.5
0.8
1.2
1.5
1.74

YDL043C
1.0
0.8
0.8
1.2
1.1
0.5
0.9
1.3
0.8
0.8
3.9
0.9
0.8
1.2
0.8
1.2
0.8
0.8
0.78

YDL212W
1.0
1.2
1.6
1.2
1.1
0.4
0.7
0.9
0.4
0.6
2.0
0.8
0.5
1.0
1.1
0.9
1.1
1.7
4.27

YDR183W
1.2
0.7
0.9
1.4
1.5
1.4
1.8
1.8
2.5
2.9
1.8
1.1
1.4
1.9
1.4
1.3
0.8
1.0
0.61

YGL089C
0.4
0.7
2.0
1.0
1.5
0.5
0.4
1.0
0.0
1.9
2.3
0.4
0.2
1.4
0.9
0.2
0.3
0.6
3.00

YGL096W
1.9
2.9
1.2
2.5
0.9
0.5
1.8
1.7
2.1
3.6
1.7
1.1
1.2
1.4
0.8
1.7
1.1
1.1
0.54

YGR006W
1.2
1.1
0.9
2.9
0.5
0.5
1.0
1.2
0.7
0.9
1.6
0.8
1.4
1.1
1.2
1.5
0.9
1.0
0.40

YHL034C
0.7
1.0
0.7
0.8
1.9
1.1
1.4
1.4
1.9
1.9
2.2
0.8
1.6
1.0
1.4
1.6
1.2
1.5
2.11

YHR163W
0.9
1.2
1.3
1.2
0.8
1.9
0.9
1.3
1.4
1.1
2.9
0.7
1.1
1.5
0.7
1.2
1.1
1.2
1.71

YIR024C
1.5
0.9
0.9
2.0
1.1
0.8
1.5
1.4
5.6
2.9
6.3
1.1
1.6
2.6
0.9
2.2
0.9
1.4
0.75

YKL070W
1.0
0.8
1.7
0.9
1.3
1.1
1.1
1.5
15.0
11.0
10.4
0.6
1.0
2.2
0.8
0.9
1.0
0.9
0.29

YLL050C
1.4
1.0
1.2
1.7

1.9
1.4
1.3
1.0
1.0
2.3
0.9
1.8
1.2
1.6
1.3
1.2
2.1
3.43

YLR220W
0.9
0.6
3.0
1.0
0.9
0.3
0.4
1.0
0.4
0.4
2.4
0.7
0.5
1.4
0.7
1.1
0.8
0.8
2.28

YLR390W
0.9
0.9
1.2
1.7
1.2
0.7
1.5
0.8
1.7
1.7
1.9
1.0
1.1
1.1
0.5
2.0
1.0
0.9
0.51

YOL044W
1.0
1.4
1.0
1.3
1.0
1.2
1.2
1.1
1.6
1.4
2.1
0.7
1.3
1.1
0.6
1.3
1.6
1.9
0.65

YOL147C
1.6
1.1
2.4
1.5
0.7
0.9
0.6
1.5
0.5
0.7
2.8
0.7
0.8
0.9
0.8
2.4
2.0
1.7
1.09

YDR069C
1.4
0.8
3.0
1.5
1.6
0.7
1.0
1.8
1.8
4.5
0.8
0.7
1.3
1.2
1.0
1.3
1.0
1.3
0.33

YER131W
1.5
0.3
0.9
0.7
1.6
0.9
0.6
2.0
0.0
0.6
1.0
0.9
0.2
0.8
0.9
0.4
0.9
0.9
5.32

YGR044C
0.8
1.3
0.7
1.2
1.1
1.4
1.3
1.8
0.9
0.8
2.1
0.8
1.4
1.0
0.5
3.3
1.1
2.6
1.43

YMR240C
1.1
0.6
2.5
0.7
1.4
0.8
1.1
2.3
0.5
1.1
1.4
0.6
0.8
1.1
1.0
1.0
1.1
1.1
0.39

YBR105C
1.7
1.5
0.9
2.0
0.8
1.8
2.0
1.2
1.1
3.3
1.1
1.2
1.1
1.7
1.4
1.3
1.3
1.1
0.96

YBR182C
2.0
1.9
1.0
2.4
1.4
1.0
1.7
1.3
0.6
3.2
1.5
1.3
1.2
1.2
3.1
1.1
3.4
1.6
0.41

YBR186W
1.0
1.0
1.1
1.7
1.0
0.5
0.9
0.9
1.0
2.4
0.9
0.8
0.7
1.1
0.9
1.2
0.7
1.0
0.31

YEL052W
1.1
1.0
2.0
2.0
1.3
1.2
1.2
1.2
3.0
3.4
1.7
1.1
1.5
1.1
0.7
2.1
0.9
1.0
0.90

YER098W
0.9
0.9
0.5
1.1
1.4
1.6
1.3
1.7
2.8
3.3
1.4
1.0
1.1
1.3
0.9
1.7
1.2
1.5
0.35

YGL240W
0.9
1.2
0.8
1.8
1.2
1.1
1.2
0.8
2.0
3.4
0.9
0.8
1.7
1.3
1.1
1.0
1.2
0.8
0.48

YGR067C
2.2
1.4
1.2
4.6
1.6
1.3
1.5
1.5
0.7
6.7
1.0
0.7
1.0
0.9
1.2
1.7
1.2
1.0
0.11

YGR133W
1.0
1.1
0.7
0.6
1.3
1.2
1.2
1.2
1.3
3.6
1.6
0.9
1.2
1.4
1.0
1.5
1.0
1.0
0.35

YHR124W
1.1
1.1
1.5
2.0
0.9
0.8
1.2
1.1
3.0
6.8
1.1
1.2
1.7
2.7
0.8
1.8
1.3
1.1
0.24

YJL103C
1.3
1.8
3.8
1.3
1.1
1.0
0.7
0.8
2.3
2.4
1.5
0.8
1.4
1.0
1.3
0.9
1.4
1.2
0.44

YJR036C
1.2
1.2
1.0
4.3
1.5
0.9
1.0
1.0
1.4
3.0
1.1
0.9
1.1
1.3
1.8
2.0
0.9
1.2
0.31

YLR216C
1.2
2.3
3.3
1.1
1.2
1.2
5.2
1.3
14.1
4.1
1.8
0.7
1.2
1.1
1.2
1.5
1.2
1.3
1.44

YLR389C
0.8
6.4
2.3
0.6
0.7
0.2
1.0
1.0
2.4
2.8
0.9
0.8
1.9
0.8
1.0
1.4
1.0
1.0
0.60

YNL128W
1.3
4.6
1.1
0.8
1.2
1.1
1.0
1.3
2.9
2.4
0.9
0.9
1.4
1.4
1.1
0.6
0.9
0.9
0.21

YOL133W
1.0
1.6
1.4
1.2
0.9
1.6
1.8
1.0
4.7
3.8
1.5
0.6
1.0
1.4
1.3
2.0
1.3
1.3
0.87

YOR133W
1.1
1.3
1.6
1.3
1.3
0.9
1.1
0.8
3.1
4.9
1.3
0.8
1.3
1.1
1.8
1.3
1.2
1.2
0.26

YOR227W
1.1
2.4
3.2
0.9
0.5
1.0
1.0
0.7
2.9
3.0
1.2
1.0
1.7
1.1
3.7
2.2
0.8
1.3
0.35

YPR015C
1.3
1.3
1.5
1.7
1.1
0.7
1.3
1.2
5.6
5.3
1.0
0.7
1.5
1.5
1.6
2.0
1.0
1.0
0.32

YPR086W
1.0
1.4
0.7
0.7
1.2
1.1
1.6
1.3
3.0
2.9
1.3
0.8
1.0
1.0
1.3
1.4
1.2
1.2
1.37

YBL056W
0.7
0.7
1.1
1.2
1.8
1.6
1.4
1.3
3.6
2.2
0.7
0.9
2.7
0.9
1.0
1.7
1.1
1.5
2.49

YBR026C
1.1
1.7
2.8
0.9
1.2
0.1

1.1
3.4
1.6
1.6
1.2
1.5
1.5
0.7
0.5
0.8
0.9
0.59

YBR123C
0.8
0.7
1.6
1.8
1.1
1.3
0.9
0.9
3.2
2.5
1.1
1.0
1.4
1.1
1.0
1.2
0.8
1.0
0.62

YDR099W
0.9
1.0
2.0
1.3
1.1
2.2
1.3
1.1
2.4
1.3
1.1
0.9
1.5
0.9
1.9
1.4
1.2
1.7
3.51

YDR177W
1.2
1.7
1.0
1.0
1.0
1.4
1.3
1.6
3.5
1.9
1.3
1.2
1.7
2.4
0.8
1.3
1.3
1.5
1.77

YDR392W
0.9
2.9
1.1
1.3
1.2
0.6
1.1
1.1
4.3
1.5
1.2
0.8
1.4
1.3
1.1
1.4
1.0
1.2
0.63

YDR394W
0.9
1.2
1.3
0.8
1.2
1.1
1.2
1.3
3.8
2.0
1.8
0.6
1.0
1.2
1.1
1.0
1.1
0.8
0.97

YER184C
2.3
1.6
1.1
2.3
1.0
0.6
0.9
1.1
4.6
3.2
1.3
0.8
1.6
1.4
1.4
1.2
1.6
2.3
0.29

YFL059W
1.2
1.4
1.2
2.2
1.1
1.0
1.3
1.5
4.1
4.2
1.5
1.2
2.3
2.4
0.9
1.6
1.3
1.1
0.57

YGL185C
1.3
1.9
1.9
1.9
0.8
0.8
1.9
1.5
4.1
2.3
1.5
1.5
1.7
1.5
0.9
15.8
1.3
1.6
0.23

YHL019C
1.1
0.8
1.2
0.6
1.0
1.2
1.1
1.0
2.1
1.4
1.3
0.8
0.8
0.8
1.2
1.3
1.0
1.0
0.55

YHR012W
1.1
1.0
1.2
1.0

1.6
1.2
1.2
4.9
2.2
1.5
0.9
1.7
1.7
1.0
1.0
1.2
1.4
1.11

YHR028C
0.8
1.2
1.4
0.8
1.0
0.9
1.2
0.8
3.7
2.2
1.4
0.7
0.6
1.1
1.1
0.7
1.0
1.0
0.92

YHR109W
0.8
1.0
0.0
0.7
1.3
1.4
1.4
1.2
2.4
1.8
0.7
1.0
1.4
1.5
0.9
1.3
0.9
1.1
0.22

YHR156C
1.3
1.3
0.9
2.1
1.9
1.0
1.2
1.2
3.6
1.9
0.6
0.7
1.0
1.9
1.2
1.4
0.9
1.3
0.47

YIL159W
1.1
1.6
1.3
0.7
1.2
2.3
0.6
1.1
5.9
1.6
0.8
0.9
1.5
2.0
1.0
0.7
0.9
0.8
0.29

YJL154C
0.6
2.7
0.7
0.6
1.2
1.3
1.5
1.0
2.3
2.0
0.5
0.9
1.6
0.8
1.2
1.2
1.2
1.1
0.62

YJR110W
1.0
0.6
1.0
1.4
1.3
0.9
0.9
1.1
4.9
2.3
1.2
0.7
0.9
1.1
1.2
1.1
0.8
1.0
0.58

YKL025C
0.7
1.1
1.1
0.9
1.1
0.9
0.9
0.9
2.8
1.7
1.1
0.8
1.3
0.9
1.2
1.1
0.9
1.0
0.54

YKL171W
0.9
1.3
1.2
2.1
0.9
0.4
0.9
0.8
8.2
1.8
2.8
1.1
1.5
1.1
1.2
2.1
0.9
1.2
0.45

YKL196C
1.2
1.1
0.5
0.9
1.3
0.9
1.5
1.3
4.3
2.0
1.6
1.0
1.8
2.5
1.9
1.9
1.3
2.0
2.41

YKR068C
1.2
1.5
1.0
1.8
1.1
1.4
1.4
1.3
2.4
1.9
1.0
1.0
1.1
1.6
0.8
1.4
1.4
1.7
1.72

YLR144C
0.8
1.5
4.0
1.3
0.7
0.9
0.7
1.1
2.8
1.5
1.0
0.7
2.3
1.2
1.9
1.7
1.0
1.0
0.44

YML112W
1.0
1.0
1.1
2.0
1.0
1.4
0.9
1.3
3.2
2.4
1.0
1.0
1.3
1.8
0.8
0.9
0.8
0.9
0.49

YOL038W
0.9
1.0
0.4
1.6
1.8
1.2
1.4
1.4
3.5
2.7
2.0
0.9
1.8
2.1
1.7
1.6
1.1
1.4
1.29

YOR257W
1.1
2.5
0.8
1.1
1.1
0.8
1.3
1.5
3.4
1.4
1.0
0.7
0.8
1.5
0.7
1.6
1.1
1.6
0.68

YOR265W
1.4
1.0
0.8
1.0
1.2
1.4
1.3
1.4
3.5
2.2
1.3
0.8
1.8
2.5
1.2
1.1
1.0
1.2
0.93

YPL124W
1.3
1.3
0.7
0.7
1.6
0.8
0.9
1.8
2.2
1.0
0.9
0.7
0.9
1.6
0.6
0.8
1.3
1.2
0.41

YPR125W
0.6
1.3
0.9

1.2
0.7
1.3
1.2
4.1
1.8
0.9
1.1
1.9
1.6
2.0
0.6
0.8
0.7
0.73

YPR168W
0.9
1.0
0.2
0.5
1.3
0.4
1.1
1.1
4.7
2.7
1.2
0.5
1.0
1.1
1.2
1.3
0.9
0.8
0.29

YPR180W
0.9
1.2
1.6
1.0
1.0
0.8
2.4
1.3
2.3
1.1
0.5
0.7
1.3
1.2
1.3
1.0
1.0
1.4
0.61

YPR193C
1.0
2.2
0.6
1.1
1.4
1.3
1.4
1.1
3.5
4.1
0.1
0.9
1.6
1.6
0.9
1.6
1.1
0.9
0.17

YBR045C
0.9
1.0
2.2
0.7
1.0
0.8
0.8
1.0
3.6
1.1
0.4
1.3
1.3
1.0
2.0
0.8
1.1
0.9
1.29

YBR128C
1.0
1.1
2.1
1.0
1.1
1.5
2.1
1.2
2.8
1.2
1.3
0.7
1.3
1.4
1.4
2.0
1.2
1.8
0.44

YCL055W
0.7
2.2
0.7
1.3
1.2
1.4
1.0
1.3
2.1
1.5
1.4
0.9
0.9
1.8
1.5
0.7
0.8
1.1
0.66

YCR019W
1.0
1.6
1.0
0.8
1.4
1.5
1.1
1.5
2.8
1.6
2.0
1.0
1.6
1.2
0.7
1.4
1.0
1.0
0.45

YDL065C
1.2
0.9
1.0
0.7
1.4
1.1
1.3
1.4
2.4
1.5
1.4
0.6
0.7
1.4
1.3
1.5
1.1
1.2
1.08

YDL143W
0.8
0.8
1.2
1.1
1.0
1.0
0.9
1.2
2.1
1.8
1.3
1.1
1.9
0.9
1.4
0.9
0.8
0.8
1.86

YDL197C
1.0
1.1
0.9
2.1
1.5
1.2
1.0
1.0
2.6
1.5
1.1
0.8
1.4
1.1
1.3
0.9
1.3
0.8
0.31

YDL230W
1.0
0.8
1.2
1.3
1.4
0.9
1.1
0.9
2.6
1.2
0.9
0.6
1.3
1.0
1.4
1.7
1.0
1.2
0.42

YDR212W
0.8
1.2
1.3
0.8
1.4
1.4
1.0
1.3
3.5
1.7
1.8
0.8
2.0
1.0
1.2
0.7
0.6
1.0
2.13

YDR257C
0.8
5.3
0.6
0.8
1.6
1.1
1.0
1.0
3.0
1.6
1.3
0.7
1.0
1.0
1.3
1.0
1.1
0.8
0.62

YDR329C
0.9
0.8
1.0
1.7
1.9
1.2
1.6
1.2
2.5
1.0
1.0
0.8
1.1
1.1
1.0
1.6
1.2
1.6
0.95

YDR488C
1.0
0.3
0.9
0.9
0.9
0.9
0.7
0.9
2.1
0.4
0.4
0.6
1.3
0.8
3.5
0.7
0.9
0.9
0.32

YDR505C
0.8
1.0
1.0
1.4
1.2
1.1
1.2
0.8
2.5
1.0
1.0
0.7
1.6
0.9
1.1
1.6
1.0
1.5
0.84

YDR506C
0.9
0.7
1.3
0.7
0.9
0.9
0.6
1.0
1.9
1.4
1.1
0.9
0.3
0.5
0.9
0.4
0.6
0.5
1.90

YDR515W
0.9
1.1
0.8
0.8
1.5
0.8
0.6
1.4
5.8
2.7
1.0
0.8
0.7
0.8
1.3
0.5
0.7
0.5
1.02

YEL005C
1.1
1.3
0.8
1.1
1.6
1.9
2.0
1.2
2.3
1.6
1.6
0.8
1.2
1.7
0.8
3.4
1.1
1.4
0.45

YER048C
0.8
1.2
0.4
1.4
1.8
1.9
1.9
1.6
2.3
1.1
1.6
0.8
1.1
1.0
0.6
1.8
1.3
1.6
1.08

YER078C
0.9
0.8
1.8
0.8
0.9
1.4
1.3
1.1
2.3
1.5
1.3
1.0
1.5
1.0
0.9
1.0
0.9
0.9
0.49

YER089C
0.5
0.5
1.4
1.1
0.8
0.6
0.9
0.5
2.0
2.3
1.2
0.7
1.3
0.6
1.0
0.8
0.7
0.6
0.75

YER100W
1.1
1.1
0.7
0.7
0.9
0.5
0.6
1.2
2.3
1.6
1.1
0.8
0.7
0.8
1.0
1.1
1.1
0.7
0.95

YFR051C
0.5
1.1
2.2
0.5
0.5
0.2
1.0
0.8
2.5
1.4
1.3
1.2
1.5
0.8
3.0
0.8
1.1
0.9
0.53

YGL093W
0.8
0.9
1.2
0.6
0.9
1.0
0.8
0.8
4.5
1.6
1.1
0.6
0.7
0.8
1.4
1.0
0.9
1.2
0.56

YGL105W
0.9
0.8
1.1
0.8
1.3
1.5
0.7
1.2
1.8
1.4
1.4
1.1
1.0
1.1
0.9
1.0
0.8
0.9
3.01

YGL166W
1.0
1.4
0.6
1.5
1.3
1.0
1.5
1.2
1.8
2.4
1.0
1.1
1.9
1.1
0.9
1.2
2.1
1.9
0.73

YGL215W
0.7
1.2
1.2
0.9
1.0
0.9
1.0
0.7
2.2
1.8
0.8
0.7
1.0
0.8
1.0
1.2
0.7
0.9
1.31

YGL216W
0.7
1.3
0.8
1.0
1.2
1.5
1.0
1.0
2.6
0.5
0.5
1.0
1.4
1.0
1.1
0.8
1.1
0.9
0.37

YGL221C
1.1
1.2
1.0
1.1
0.9
2.2
1.3
1.6
3.4
1.9
1.4
1.1
1.7
1.7
0.7
1.3
1.1
1.4
1.64

YGR186W
0.9
0.7
0.4
1.1
1.5
0.7
1.3
1.3
2.6
1.9
1.0
0.6
1.1
1.1
1.3
1.4
1.3
1.2
0.79

YGR270W
0.9
1.0
0.8
0.8
0.7
0.9
0.9
0.9
2.3
1.3
0.7
0.8
1.3
0.9
1.6
1.0
0.9
0.9
0.51

YGR274C
0.7
0.5
0.3
0.9
1.8
0.7
1.3
1.2
2.2
1.8
0.9
0.7
1.1
0.8
1.2
0.7
1.1
1.0
0.62

YHR082C
0.7
1.1
1.6
0.9
1.6
0.8
1.1
0.8
2.6
1.7
0.9
0.7
1.7
0.9
1.4
0.7
1.1
0.9
0.60

YHR160C
1.0
0.5
1.6
1.6
1.0
1.0
1.1
1.2
2.3
1.6
−0.2
0.8
1.8
1.2
2.1
4.4
1.0
1.5
0.32

YHR171W
1.2
0.8
1.1
1.2
1.3
2.0
1.9
0.9
2.1
1.6
1.2
0.8
1.3
1.0
0.7
1.6
1.2
1.5
0.41

YHR205W
0.7
1.3
0.6
0.8
1.3
1.0
0.7
0.5
2.0
0.6
0.9
0.9
1.7
0.9
1.5
0.8
0.9
0.8
0.34

YIL062C
1.1
1.0
1.3
1.2
1.2
0.9
0.4
1.1
2.8
2.3
1.7
0.8
1.1
2.0
0.9
0.4
1.1
1.1
1.72

YIL075C
0.5
0.7
1.5
0.6
1.1
0.8
0.8
0.7
1.9
2.3
0.8
0.8
0.7
0.8
1.6
0.8
0.8
0.8
1.54

YIR009W
0.8
0.8
0.9
2.8
1.5
1.4
1.3
1.3
2.6
1.5
1.1
0.7
0.8
1.6
1.1
1.0
1.7
1.0
0.48

YIR018W
1.2
1.0
0.9
1.1
1.4
2.0
1.5
1.5
4.0
2.1
1.2
1.1
1.5
1.2
1.5
1.0
1.6
1.1
0.44

YJR091C
0.8
1.2
2.6
1.4
1.4
0.8
1.1
0.8
2.4
2.3
1.8
0.8
1.4
0.8
1.4
0.7
1.2
0.9
0.57

YKL079W
0.9
0.8
1.5
1.0
1.4
0.8
1.7
1.2
2.3
2.0
1.3
0.9
1.2
0.9
1.1
1.6
1.1
1.2
0.64

YKR102W
0.8
1.6
1.4
0.8
0.9

0.7
2.4
1.4
3.3
0.8
2.7
1.8
1.1
1.5
1.5
0.9
0.19

YLL054C
1.2
0.6
0.5
1.2
1.4
1.9
1.1
1.1
2.4
1.4
0.5
0.7
1.7
1.2
0.9
0.9
1.0
1.0
0.33

YLR200W
1.4
0.9
0.5
1.2
1.7
1.2
1.9
1.4
2.2
2.6
1.1
0.9
1.3
2.3
0.9
1.2
1.1
1.5
1.12

YLR248W
0.9
0.7
1.1
1.4
1.9
1.2
1.2
1.1
2.3
1.1
1.0
0.7
1.2
0.9
1.2
1.7
1.1
1.7
1.58

YLR266C
0.9
1.3
0.7
1.5
0.7
1.0
1.6
1.1
2.2
2.6
1.1
1.0
1.3
1.0
0.8
1.7
0.8
1.4
0.74

YML088W
0.9
1.6
0.3
0.5
1.5
0.7
1.1
1.1
4.0
2.2
0.5
1.0
1.3
1.1
1.4
0.8
0.8
0.8
0.58

YMR091C
1.0
0.7
0.8
1.0
0.7
0.8
0.8
1.3
2.1
1.3
0.9
0.8
0.9
1.5
0.9
1.3
0.9
1.2
1.03

YMR110C
1.0
1.4
1.8
1.9
1.3
2.1
1.9
0.9
2.3
1.6
1.6
0.9
1.8
0.8
0.9
2.7
1.5
2.5
1.63

YMR255W
1.2
1.4
0.7
1.8
1.3
0.9
1.5
1.4
2.8
2.4
1.2
0.9
1.1
1.6
1.0
1.3
1.5
2.0
0.97

YNL039W
0.7
0.8
0.3
0.4
2.1
0.8
1.1
1.2
2.1
1.8
0.4
0.9
0.8
0.8
1.3
1.3
0.9
1.1
0.61

YNL077W
1.5
1.1
2.3
1.2
1.5
0.9
1.2
1.0
4.4
5.1
1.0
0.7
1.5
0.5
0.3
0.6
1.3
1.0
0.78

YNL083W
0.8
1.4
1.3
1.2
0.8
0.7
0.9
1.1
3.1
1.6
0.9
0.9
1.2
0.9
0.8
1.8
0.8
1.1
0.37

YNL147W
1.3
2.4
0.6
0.7
2.0
1.5
1.4
1.8
2.1
2.9
1.2
0.8
1.0
2.0
1.2
1.7
1.0
1.6
1.32

YNR006W
1.1
1.8
0.5
0.9
1.5
0.9
1.5
0.9
2.2
2.3
0.8
0.9
1.6
0.9
1.2
1.1
1.8
1.2
0.40

YNR034W
0.9
1.4
5.3
1.6
1.0
0.9
1.3
1.0
3.0
2.1
1.3
0.9
1.4
0.9
1.1
2.3
0.7
1.1
0.64

YNR047W
0.7
1.0
1.7
0.5
1.1
1.0
1.0
0.8
2.0
1.2
0.6
0.9
1.5
0.9
1.2
1.5
0.9
1.0
0.44

YOR023C
0.7
1.2
1.3
0.8
1.2
1.8
1.1
0.6
3.5
1.3
0.9
1.1
1.9
0.9
1.6
0.8
1.1
0.8
0.37

YOR058C
2.0
1.4
2.0
0.6
0.9
0.9
0.8
1.7
6.4
4.5
1.4
0.7
1.7
1.7
1.1
1.6
0.9
1.0
0.31

YOR069W
0.8
1.6
0.7
1.3
1.0
0.5
1.2
1.1
1.9
1.4
2.8
0.9
1.1
1.3
1.4
1.5
0.8
1.1
0.69

YOR229W
0.9
0.9
1.0
0.8
1.5
1.3
1.1
0.8
2.5
0.8
0.7
0.8
1.3
1.0
1.2
0.9
0.9
1.0
0.58

YOR256C
1.0
0.8
0.9
1.5
1.7
0.9
1.4
1.1
2.7
1.8
1.7
0.7
1.6
1.1
1.1
1.5
1.2
1.5
0.53

YPL020C
1.1
0.7
0.7
1.3
0.8
0.8
1.1
1.1
2.3
1.6
1.1
0.9
1.1
1.1
1.6
1.2
1.3
1.4
0.91

YPL105C
0.6
0.8
0.6
0.7
1.1
1.2
0.7
1.0
3.4
1.4
0.6
0.7
1.0
0.6
1.1
0.5
0.8
0.6
0.80

YPR066W
1.2
2.2
1.1
2.2
1.3
0.7
1.3
0.8
2.3
1.9
0.9
0.8
1.4
1.2
0.7
1.6
1.1
1.2
0.41

YPR081C
0.9
1.0
1.0
1.1
0.8
1.1
1.1
1.0
4.2
2.6
0.9
1.0
1.4
1.1
1.3
1.8
0.9
1.3
0.34

YPR140W
0.9
1.2
0.8
1.8
0.9
3.0
1.9
1.1
2.1
1.3
0.8
0.8
1.3
1.4
1.7
2.4
0.8
1.3
0.47

YPR155C
0.9
2.5
1.5
1.4
0.9
0.9
1.4
1.0
2.0
1.3
0.9
0.9
1.3
1.2
0.5
3.4
0.8
1.6
0.40

YPR185W
0.7
0.9
0.3
0.4
1.1
0.9
1.2
1.0
2.5
1.7
0.9
0.8
1.7
1.0
1.1
1.3
1.3
1.1
0.68

YBR076W
2.3
1.1
1.4
5.0
0.9
0.8
1.0
0.7
0.4
1.8
0.8
0.9
1.9
1.2
1.1
0.5
1.4
1.2
0.36

YDR373W
1.7
0.8
0.5
1.3
1.8
0.9
1.4
1.9
2.5
2.8
1.7
0.5
1.0
2.1
1.6
1.4
1.2
1.6
1.08

YFR014C
2.1
2.4
0.8
2.6
0.7
0.8
1.4
1.3
1.0
1.6
1.8
0.9
1.3
1.0
0.6
2.3
1.2
2.9
0.94

YHR136C
2.4
13.6
1.4
2.1
2.4
1.4
0.5
1.3
0.1
2.0
2.0
1.2
0.3
1.7
0.5
1.3
1.6
2.5
1.33

YIL129C
0.8
5.8
1.0
1.2

0.3

2.1
1.8
1.5

1.9
0.9
1.0
1.0
1.3
0.8
0.25

YMR077C
1.1
3.9
1.1
1.8
1.0
0.5
1.4
1.7
1.9
2.5
1.5
0.9
0.8
1.6
1.7
2.3
0.9
1.3
0.59

YBR264C
1.2
3.7
1.5
1.5
0.7
0.9
1.3
1.2
0.9
1.1
1.0
1.0
0.9
1.6
1.1
1.8
0.9
1.3
0.61

YPL177C
1.2
3.7
0.9
1.3
0.7
0.8
0.8
1.3
0.5
1.0
1.4
0.8
0.8
1.3
0.6
1.9
1.2
1.1
0.75

YGL056C
0.7
3.5
1.3
1.0
0.6
0.4
1.0
0.9
0.4
0.6
0.0
1.1
0.8
1.1
1.2
1.5
0.9
1.1
0.47

YBL101W-A
1.0
5.7
0.7
0.6
1.0
1.4
1.3
1.5
1.2
2.1
1.2
1.1
2.0
1.5
2.1
1.1
1.3
1.2
1.24

YER072W
1.6
2.3
1.6
1.3
1.2
1.5
0.7
1.2
0.5
1.1
1.7
1.1
0.6
1.5
0.9
1.1
1.7
1.7
1.69

YMR112C
1.2
4.2
0.9
1.2
1.0
0.7
1.5
1.6
1.4
1.3
0.9
1.0
0.9
1.8
0.9
1.4
1.1
1.6
0.57

YJR058C
1.3
2.0
1.3
1.5
1.1
1.6
1.3
1.2
1.9
2.6
1.2
0.7
0.8
1.8
0.8
1.2
1.3
1.2
1.00

YML055W
1.7
2.3
0.6
2.0
0.9
1.2
1.7
1.7
1.0
1.4
1.4
1.0
1.7
1.9
0.6
1.4
1.2
1.5
1.08

YDR080W
0.9
1.8
0.5
0.6
1.2
1.5
1.6
1.2
1.7
2.6
1.2
1.0
2.0
1.1
1.2
1.7
1.2
1.3
0.68

YNR030W
0.6
2.1
2.2
0.7
0.8
1.2
1.0
0.6
1.0
1.4
1.2
0.8
1.5
0.6
1.1
0.4
0.9
0.8
1.19

YNL196C
1.1
1.8
1.4
1.3
0.9
1.2
1.0
0.7
0.5
2.2
0.7
1.0
2.2
1.2
0.8
2.1
1.1
1.2
0.50

YOR148C
1.4
1.4
0.5
1.8
0.9
0.9
1.2
1.5
0.8
0.8
1.3
0.9
1.4
1.4
1.0
1.3
1.0
1.3
1.08

YER029C
1.0
1.6
0.4
1.9
1.7
1.2
1.1
1.5
1.4
1.1
0.8
0.9
0.9
1.4
1.1
1.7
0.9
1.3
1.20

YLR360W
0.9
2.0
0.5
0.7
1.9
1.4
1.7
1.3
0.9
1.3
0.9
0.9
0.7
1.1
0.8
2.1
1.2
1.4
0.53

YGR239C
1.3
1.3
0.7
1.3
1.2
2.3
1.2
1.5
0.5
3.8
1.4
1.0
1.0
1.4
1.3
1.1
1.1
1.3
0.49

YDL229W
0.9
1.9
0.4
0.6
1.2
1.0
1.3
1.2
1.4
0.9
1.6
0.9
1.0
1.3
1.2
1.0
1.2
1.1
0.76

YJR027W
0.8
1.9
0.8
0.7

1.5
2.0
1.0
1.2
1.3
1.1
0.8
1.3
1.1
2.3
0.7
0.7
1.1
4.88

YKL198C
1.2
1.4
0.8
0.2
0.9
1.0
1.2
0.6
0.0
0.8
1.4
0.7
1.9
6.6
2.6
0.7
1.0
0.8
0.17

YBR031W
1.1
0.8
4.1
1.4
1.4
0.7
0.5
1.0
0.1
1.0
0.9
1.0
0.3
0.4
0.9
0.7
1.0
0.8
7.58

YBR118W
1.3
0.8
2.9
1.2
1.0
1.3
1.0
1.3
0.5
0.9
1.0
0.8
0.8
0.7
1.6
0.6
1.2
0.9
8.91

YCR106W
0.9
1.1
2.8
1.1
0.8
1.4
0.9
0.8
2.0
1.2
1.2
0.8
1.2
0.8
1.3
1.2
1.1
1.2
0.76

YDR012W
0.9
0.8
3.9
1.2
1.1
0.9
0.5
1.1
0.3
0.7
0.9
1.2
0.2
0.4
0.8
0.7
1.0
0.7
7.07

YDR134C
1.0
0.7
3.9
1.9
0.8
1.1
0.4
0.6
0.1
0.5
1.9
0.6
0.4
0.5
0.8
0.9
0.7
1.1
5.84

YDR276C
1.5
1.6
6.1
1.4
0.7
1.1
1.0
1.1
1.1
2.7
1.4
0.9
1.1
1.3
2.2
3.6
1.3
2.4
2.48

YGR279C
0.9
0.7
3.6
1.0
1.2
1.6
0.8
0.6
0.3
0.7
0.9
0.7
0.3
0.4
1.3
0.8
1.0
0.8
3.77

YJL059W
1.0
1.7
3.1
0.8
0.9
1.6
1.1
0.8
1.7
1.6
1.8
1.0
1.6
1.3
0.9
0.8
1.1
1.0
0.39

YKL056C
1.3
0.7
2.6
1.4
1.7
0.9
0.5
1.0
0.1
0.7
1.1
0.8
0.1
0.7
0.9
0.6
0.8
1.2
6.68

YKL097W-A
1.5
1.3
4.2
1.3
1.2
0.9
0.2
0.7
0.0
0.4
1.6
0.7
0.2
0.6
2.0
0.8
1.1
1.4
4.01

YNL209W
0.9
0.9
2.7
0.9
1.3
0.9
0.5
1.1
0.2
0.8
0.9
0.9
0.5
0.6
0.9
0.3
0.6
0.6
8.06

YNL307C
0.8
0.6
3.1
1.3
1.0
1.9
0.9
0.9
1.0
0.9
1.0
1.0
1.0
0.7
0.6
1.0
1.0
1.3
2.79

YPR028W
1.0
1.1
4.0
1.7
1.0
1.4
0.8
0.7
0.5
0.8
1.4
0.6
1.7
0.8
0.9
1.3
1.2
1.7
4.06

YPR149W
1.0
1.1
5.9
1.7
1.7
1.6
2.1
0.6
1.2
1.8
1.1
0.7
1.4
1.3
1.0
2.2
1.1
1.1
2.65

YAL016W
0.8
1.0
2.8
0.9
0.9
0.9
1.1
1.0
1.2
1.9
0.9
0.8
1.4
0.9
1.1
1.1
0.8
1.3
1.00

YBR283C
0.6
0.7
1.9
1.2
1.4
2.2
0.8
0.8
1.5
1.2
2.0
0.8
0.8
0.6
1.4
0.9
0.9
0.9
2.62

YBR286W
0.7
1.4
3.8
1.2
1.3
1.5
1.3
0.9
1.2
1.6
1.0
1.1
1.8
1.5
1.3
2.6
0.8
1.6
2.98

YCL008C
0.8
1.1
1.8
1.2
1.2
0.9
0.9
0.7
0.9
1.4
0.9
0.9
1.0
0.9
1.4
0.6
0.9
0.9
0.47

YCR069W
1.0
1.2
2.0
0.9
1.1
1.4
1.1
0.7
0.8
0.7
1.3
1.4
1.6
1.0
2.4
1.2
1.2
1.3
0.97

YDL061C
1.4
0.5
2.9
0.9
1.3
1.1
0.5
1.0
0.0
0.5
1.4
1.0
0.1
0.7
1.0
0.6
1.1
1.0
4.40

YDR151C
1.3
1.0
2.3
1.8
0.8
0.7
0.8
1.5
2.6
2.8
2.1
0.9
2.8
1.1
0.6
1.2
0.8
1.1
0.96

YDR382W
1.3
0.5
2.4
1.2
1.1
0.6
0.4
1.2
0.0
0.4
1.2
0.7
0.1
0.7
1.1
0.4
1.0
1.0
6.40

YDR385W
0.6
0.4
3.5
0.9
1.1
0.5
0.4
0.7
0.2
0.5
0.9
0.9
0.3
0.5
0.8
0.3
0.6
0.4
7.27

YDR407C
0.7
1.0
2.0
0.7
0.8
1.2
1.4
0.9
1.5
1.7
1.2
1.0
1.3
0.8
1.3
1.0
0.9
0.9
0.52

YGL206C
0.4
3.5
2.0
0.5
0.6
0.8
0.8
0.5
0.7
0.7
0.9
0.7
1.1
0.8
1.3
0.6
0.8
1.0
1.04

YGR172C
0.6
1.3
2.5
1.3
0.6
0.9
1.0
0.8
0.4
1.1
0.8
0.8
0.7
1.1
1.9
1.0
1.1
1.1
0.94

YIL015W
1.1
1.7
2.0
2.5
0.9
0.4
0.9
0.9
0.3
1.1
0.8
0.9
0.8
5.9
1.1
0.8
0.8
1.0
0.17

YIL018W
1.0
0.4
2.3
1.4

0.9
0.4
0.8
0.0
0.3
1.2
0.6
0.0
0.6
0.6
0.4
0.8
0.8
6.27

YJL138C
1.0
0.7
2.3
1.4
0.9
0.8
0.8
1.2
0.2
0.7
1.2
0.8
0.3
0.7
0.9
0.6
0.9
1.0
7.38

YJL191W
1.0
0.4
2.2
0.7

1.3
1.0
0.8
0.0
0.4
1.1
1.0
0.9
1.1
0.7
2.2
1.0
1.0
1.86

YJR047C
1.1
0.8
2.6
1.1
1.1
1.1
0.4
0.9
0.7
0.5
1.1
0.9
0.9
0.9
0.6
0.8
0.8
0.9
5.29

YJR119C
0.9
1.0
2.0
1.0
0.9
1.4
1.1
1.6
0.5
1.3
1.1
0.9
1.2
1.3
1.5
1.0
0.7
0.9
0.30

YJR123W
1.2
0.6
2.2
1.0
1.3
1.0
0.4
1.2
0.0
0.5
0.9
0.8
0.1
0.6
1.1
0.4
0.8
0.9
7.84

YJR145C
0.8
0.7
2.3
1.3

0.4
0.4
1.0
0.0
0.4
0.8
0.6
0.0
0.6
0.8
0.5
0.8
0.9
4.82

YLR110C
1.4
0.8
2.7
1.2
1.7
0.9
0.4
0.8
0.3
0.8
3.2
0.7
0.5
0.5
1.7
0.8
0.9
1.1
3.99

YLR264W
1.1
0.4
2.2
1.0
1.1
0.7
0.4
1.0
0.0
0.3
0.8
1.1
0.3
1.2
1.2
0.5
1.0
1.1
3.91

YLR340W
0.8
0.4
2.6
1.0
0.6
0.7
0.3
0.9
0.0
0.5
1.4
0.9
0.1
0.5
1.3
0.2
0.9
0.7
6.55

YLR388W
1.6
0.4
1.9
1.0
2.5
0.7
0.5
1.2
0.2
0.7
1.0
0.6
0.1
0.8
0.6
0.5
0.8
1.0
4.48

YMR092C
0.6
1.2
1.9
1.3
0.8
0.9
1.2
0.9
1.5
1.7
1.2
0.9
1.7
0.8
1.1
1.2
0.9
1.3
1.43

YMR101C
1.1
1.8
1.9
2.9
0.9
0.4
0.9
0.8
−4.0
1.6
−0.3
0.7
0.8
1.1
1.0
0.9
0.7
0.8
0.16

YNL069C
1.2
0.3
2.8
2.3
0.7
0.4
0.3
1.0
0.0
0.4
1.0
0.6
0.1
0.9
1.0
0.3
0.8
0.6
4.03

YNL135C
1.1
0.9
2.0
1.4
1.7
0.9
0.8
0.5
0.7
0.5
0.7
0.8
0.9
0.5
1.0
1.4
1.2
1.7
3.05

YOL039W
1.2
0.3
3.9
0.7
1.3
0.4
0.3
1.0
0.0
0.9
1.1
0.7
0.1
0.5
0.8
0.4
0.7
0.7
4.94

YOL120C
1.0
0.3
2.3
0.8
1.5
0.3
0.4
0.8
0.0
0.3
1.0
0.7
0.1
0.6
0.6
0.3
0.6
0.8
4.42

YOR230W
1.2
2.3
3.0
1.0
0.9
1.1
0.6
0.6
0.6
0.7
1.6
1.4
1.5
0.7
0.6
1.6
1.2
1.6
1.76

YOR298W
0.9
0.9
3.2
0.5
1.5
0.9
0.6
0.7
0.6
1.0
0.1
0.7
1.1
2.1
1.2
0.5
1.0
0.8
0.41

YPL048W
0.7
0.7
2.6
1.2
0.7
0.6
0.6
0.8
1.6
0.6
1.7
1.0
0.9
0.6
1.5
1.3
1.2
1.0
2.11

YPL179W
1.0
1.5
2.4
1.0
1.1
1.6
1.2
0.8
1.2
1.1
1.1
1.0
1.3
0.8
1.2
1.4
1.3
1.3
1.38

YPL218W
1.5
0.9
2.5
1.7
1.1
1.5
1.3
1.4
1.1
1.2
1.1
1.2
1.0
1.5
1.1
1.7
1.1
1.8
2.98

YPL220W
1.3
0.9
2.3
1.4
1.1
1.3
0.6
1.2
0.0
0.5
1.3
0.5
0.1
0.6
0.6
0.5
1.1
1.1
8.33

YPR080W
1.3
1.3
2.8
1.2
1.4
1.4
0.9
1.3
0.7
1.1
1.0
1.0
1.3
0.6
1.5
0.6
1.1
1.0
8.03

YPR181C
0.5
0.8
2.3
0.6
1.0
2.0
1.3
0.5
1.0
0.7
1.3
1.0
1.7
2.4
1.5
1.6
1.8
1.6
1.84

YBR290W
1.3
1.4
0.8
3.0
1.0
1.1
1.4
1.5
2.0
1.8
1.2
1.0
1.7
1.4
0.9
1.3
1.2
2.1
1.34

YCR091W
1.3
1.1
0.6
2.2
1.3
1.3
1.3
1.1
0.8
1.2
0.8
1.1
1.3
1.3
0.7
2.7
1.3
1.4
0.22

YFL026W
1.0
0.8
1.2
5.0
1.4
1.0
1.2
1.3
0.6
1.5
1.3
0.8
1.1
1.1
1.0
1.0
1.0
1.0
0.27

YOR003W
0.9
1.1
1.3
3.3
1.6
1.1
1.1
0.9
1.6
1.3
0.7
0.8
1.0
1.2
2.8
1.3
1.0
1.1
0.30

YCR038C
0.9
1.1
0.9
2.5
0.9
0.9
0.9
0.9
0.7
0.7
1.1
0.8
1.0
1.1
0.7
1.0
0.9
1.1
0.31

YDL119C
1.0
0.8
0.6
2.2
0.9
0.6
1.3
1.1
1.3
1.1
1.5
0.9
1.1
1.2
0.5
1.2
1.0
1.0
0.77

YDL220C
0.9
1.3
1.1
1.6
1.2
1.8
1.1
0.8
0.2
1.3
0.8
1.0
1.6
0.9
1.6
0.8
1.1
0.9
0.24

YDR125C
1.1
0.9
1.0
1.7
1.1
0.8
1.0
1.2
0.7
1.9
1.0
0.8
0.9
1.0
0.8
1.7
0.9
1.2
0.35

YDR225W
1.0
0.6
0.6
1.6
1.9
0.5
0.4
0.8
0.3
0.7
2.7
0.4
0.2
0.8
0.1
0.8
1.1
1.8
5.54

YER066W
0.9
0.7
0.9
2.1
1.5
1.3
1.3
0.7
1.7
1.4
1.5
0.7
0.9
1.1
0.5
3.3
1.1
1.1
0.66

YER076C
0.8
0.9
1.2
1.9
1.1
0.6
0.8
0.7
0.2
1.2
0.7
0.7
1.1
0.9
0.8
1.3
1.0
1.0
0.33

YFR006W
0.9
1.8
1.1
3.4
0.7
0.8
1.4
1.0
−1.6
0.7
1.2
1.0
0.9
0.9
0.8
1.2
0.9
1.3
1.54

YGL208W
0.9
1.8
1.1
2.2
0.7
0.6
1.1
0.7
1.4
1.3
1.3
0.8
1.5
0.9
1.8
3.1
0.8
1.3
0.32

YGR023W
1.0
0.9
1.1
4.2
1.0
1.2
1.0
1.2
1.2
3.2
2.4
0.9
1.4
1.3
1.1
0.9
1.2
1.5
0.69

YGR108W
0.9
3.9
0.3
3.6
0.8
0.1
0.3
0.5
0.0
0.1
0.5
0.4
0.3
0.8
0.2
0.4
0.7
1.0
0.93

YHR195W
1.1
1.5
0.6
2.4
1.5
1.0
1.3
1.6
1.8
0.8
1.4
0.9
1.2
1.2
0.7
3.7
1.0
1.5
1.12

YIL050W
1.0
1.3
1.3
2.4
0.9
0.7
1.1
1.2
1.3
1.9
0.9
1.0
1.0
1.3
0.6
2.7
1.0
1.1
0.52

YJR050W
1.0
0.6
0.7
2.1
1.2
1.4
1.1
1.8
2.0
1.3
0.8
0.8
1.9
1.3
0.9
1.5
0.9
1.1
0.85

YKL093W
1.0
1.6
1.4
3.6
0.8
0.8
0.7
0.9
1.5
1.6
0.9
0.9
1.2
1.1
0.8
2.9
0.8
1.0
0.38

YMR053C
1.1
1.0
0.8
2.1
0.9
1.3
0.9
1.0
2.2
1.4
1.3
0.9
1.5
1.3
2.4
2.3
1.1
1.6
0.31

YNL139C
0.8
1.1
0.8
2.0
1.9
1.0
1.0
0.9
0.6
0.7
0.8
0.5
1.2
0.7
1.4
1.1
1.1
1.0
0.47

YOR122C
1.0
0.7
1.8
1.9
1.7
1.3
1.2
1.0
1.1
0.9
1.5
0.8
1.0
1.2
1.6
1.5
1.0
2.2
3.06

YOR312C
1.2
0.4
1.0
1.9
0.7
0.6
0.6
1.2
0.0
0.3
0.8
0.7
0.1
0.7
0.7
0.5
1.2
1.0
5.24

YOR327C
2.3
1.8
0.5
1.9
1.0
1.4
1.4
1.9
1.4
2.2
2.1
1.0
2.1
1.5
0.9
1.5
2.2
2.1
1.46

YPL001W
0.9
0.9
1.0
2.5
1.7
0.7
1.0
1.2
0.7
1.0
1.3
0.7
0.8
1.3
1.3
0.8
0.9
1.2
0.74

YPL230W
1.2
1.7
1.8
4.0
0.8
1.0
1.1
1.0
0.9
2.7
3.1
1.0
2.0
1.3
0.7
2.0
1.0
1.6
0.47

YER025W
0.6
0.7
0.6
0.6
1.5
1.0
1.5
1.1
0.4
0.6
1.2
0.7
0.6
2.1
0.8
2.6
1.8
2.3
1.96

YHR185C
0.9
1.1
1.4
0.7
1.4
1.0
1.3
0.8
−0.6
0.9
0.7
0.8
0.4
1.7
1.3
3.2
1.4
3.0
1.64

YIL076W
1.3
0.6
1.1
1.0
1.8
0.6
0.5
1.3
1.0
1.4
1.1
0.8
0.8
1.4
1.0
0.8
1.2
2.5
3.73

YMR238W
1.9
1.3
1.1
1.3
1.5
1.3
1.2
0.9
1.3
1.4
1.2
1.0
1.5
1.2
2.3
1.4
2.2
2.4
1.36

YBR009C
1.6
0.8
0.4
1.7
1.4
1.0
0.5
1.2
0.6
0.6
0.8
0.5
0.4
1.1
0.2
0.4
1.0
2.4
7.00

YBR010W
1.0
0.8
0.5
2.0
0.8
1.1
0.8
1.3
0.5
0.7
1.0
0.7
0.4
1.0
0.3
0.8
1.1
2.3
7.25

YCL067C
1.2
1.1
0.3
1.7
1.1
1.7
1.3
1.7
1.4
1.9
1.6
1.0
1.4
2.1
2.2
1.7
0.8
2.2
3.15

YCR096C
1.1
0.9
0.4
1.6
2.1
1.2
1.7
1.5
1.2
1.6
1.4
1.0
1.0
2.1
2.1
1.8
1.0
2.1
2.34

YDL137W
1.4
1.1
1.2
1.2
1.8
1.0
2.0
1.1
1.1
1.3
1.5
1.6
1.7
1.4
1.3
2.3
1.3
2.2
4.95

YDL192W
1.4
1.0
0.6
1.2
1.4
1.0
1.7
1.5
0.8
0.6
1.3
1.1
0.9
1.2
1.3
1.3
1.1
2.3
5.57

YDR224C
1.1
0.7
0.8
0.9
1.2
1.0
0.8
1.4
1.1
1.3
1.1
0.7
0.5
1.7
0.3
1.1
1.2
2.2
5.62

YDR378C
1.3
1.3
1.4
1.3
1.0
1.0
1.4
1.5
0.5
1.3
0.8
0.9
0.8
1.4
0.8
1.0
1.7
2.2
2.40

YMR197C
1.3
1.6
1.4
1.9
1.1
1.6
1.5
1.4
1.9
2.5
1.0
1.1
1.5
4.1
1.7
1.9
1.2
2.2
1.20

YOL109W
2.0
2.0
1.5
1.8
1.0
1.3
1.2
1.5
0.1
1.1
1.0
0.8
0.5
1.4
1.0
0.8
1.6
2.2
4.13

YPL010W
1.0
1.1
0.9
1.0
1.4
1.0
1.9
1.5
1.7
1.5
1.3
1.1
1.1
1.3
1.2
1.3
1.3
2.0
3.25

YHR132C
0.8
0.7
1.7
1.4
1.0
0.7
0.8
0.8
0.9
1.1
1.1
0.8
1.2
0.9
1.4
2.3
0.8
1.3
1.52

YJL141C
1.0
0.8
1.0
1.6
1.5
1.1
1.1
0.9
1.2
1.3
1.2
0.8
1.4
0.8
0.8
2.2
1.4
1.6
0.94

YKR098C
1.0
1.1
1.2
1.7
1.1
1.8
1.7
1.3
1.4
2.7
1.9
1.1
1.4
1.4
0.9
3.9
1.1
1.6
0.55

YLR206W
0.7
1.6
1.4
1.1
1.1
0.5
0.7
0.8
1.5
1.0
1.3
0.8
1.4
0.8
2.4
2.3
1.1
1.2
0.72

YAL055W
1.2
1.0
0.9
1.0
1.4
1.3
1.5
1.9
1.0
1.4
1.3
1.2
1.5
1.6
1.1
2.6
1.3
1.3
0.62

YAR062W
1.2
1.8
1.4
0.7
1.0
0.6
1.3
0.9
0.4
0.9
−1.1
0.8
1.2
1.1
1.3
2.4
0.9
1.0
0.32

YBL102W
0.8
1.0
1.4
1.2
0.9
2.5
1.6
0.8
2.3
1.1
1.2
0.9
1.7
1.1
1.1
2.0
2.4
1.5
1.26

YBR161W
1.2
0.8
2.3
0.7
1.1

3.0
0.9
0.4
0.4
1.1
0.6
1.0
0.9
1.5
2.1
1.5
2.2
0.72

YCR039C
1.9
2.1
0.3
0.9
1.9
1.5
1.4
1.6
1.8
2.2
1.2
0.8
1.0
1.7
1.9
2.1
1.0
2.1
1.73

YDL018C
1.3
0.9
0.9
1.1
1.8
1.4
1.2
1.3
1.0
1.0
0.9
0.7
1.0
1.5
1.1
3.1
1.5
1.7
0.84

YDR022C
1.1
1.2
0.8
0.9
1.5
2.2
1.8
1.4
0.9
1.4
0.9
0.7
1.3
2.1
1.0
2.1
1.3
1.2
0.47

YDR181C
1.1
1.2
0.8
1.4
0.9
0.7
1.0
1.2
2.0
0.9
0.8
0.7
0.7
1.3
1.2
2.0
0.8
1.2
0.48

YGR036C
0.9
0.8
0.9
1.1
1.3
1.3
1.0
0.8
0.9
0.9
0.9
1.0
1.3
1.0
0.7
2.0
1.3
1.1
1.12

YGR120C
1.2
1.8
0.5
1.0
1.8
1.5
1.6
1.3
0.3
1.2
1.1
0.7
0.5
1.0
1.2
1.9
1.1
1.2
0.36

YGR131W
0.8
2.1
1.9
1.1
0.9
1.9
1.1
1.1
1.9
5.8
1.1
0.5
1.4
2.0
0.8
2.6
1.3
1.0
0.41

YGR167W
1.1
1.1
0.6
1.5
0.9
1.7
1.4
1.4
1.4
1.9
1.1
1.1
1.6
1.7
1.6
2.8
1.3
1.7
1.79

YHL024W
1.2
0.8
1.6
1.1
1.5
1.2
1.3
0.8
2.1
3.6
1.1
1.6
1.6
2.1
2.9
3.8
1.4
1.4
0.58

YJL113W
1.2
1.9
1.2
1.2

0.7
1.2
1.3
1.3
2.1
1.2
0.7
0.9
1.3
1.7
2.1
0.9
1.5
0.41

YJL146W
1.3
1.9
1.2
2.0
0.8
0.7
1.3
1.0
1.0
1.7
−1.1
1.1
0.8
1.5
1.2
1.8
1.0
1.3
0.30

YJR019C
0.8
1.8
1.9
1.6
1.1
0.8
0.9
0.7
1.1
0.6
2.4
1.1
1.4
0.8
1.1
2.6
1.8
1.4
0.33

YJR049C
1.0
1.2
1.0
1.0
0.7
0.6
1.0
1.2
1.4
1.4
1.6
1.0
2.1
1.2
1.2
1.7
0.9
1.2
0.44

YLR078C
0.9
1.1
0.7
1.4

0.8
1.2
1.1
0.8
1.1
2.9
1.0
0.8
1.2
0.6
2.2
1.2
1.2
1.02

YNR037C
0.9
0.9
0.9
1.7
1.2
0.7
1.7
1.1
1.3
1.7
1.5
0.7
2.0
1.2
0.8
1.9
1.4
1.6
1.34

YOR028C
1.4
0.7
1.1
2.3
1.6
1.0
1.2
1.5
1.2
2.0
1.5
0.6
0.8
1.3
1.1
3.7
0.8
1.7
0.78

The tables show that the expressed mRNA of about 700 of 2400 unknown yeast genes was induced by any one of toxic chemical substances such as heavy metals, agricultural chemicals, surfactants (Table 1), as well as the expressed mRNA of 167 mitochondria-located genes (Table 2), 52 DNA repair genes (Table 3), 161 energy genes (Table 4), 142 transport facilitation genes (Table 5), 90 stress protein genes (Table 6), 142 metabolism genes (Table 7), 60 detoxification genes (Table 8), and 507 genes belonging to other category (Table 9). Here, when the value of the following is 2 or more, then it is considered significant:
$\frac{The level of expressed mRNA in the presence of chemical substance}{The level of expressed mRNA in the absence of chemical substance .}$

“Intensity” indicated in the rightmost column of Tables 1 to 9 is a value of the level of expressed mRNA of each gene in control cells as divided by the average level of the expressions of the whole genes. When the intensity is low, the error of measurement may be possibly large. The detection is considered more precise when expression magnification (expressed mRNA in the presence of chemical substance/expressed mRNA in the absence of chemical substance) is larger. Yeast gene as used in the processes according to the invention is selected, of which the intensity is preferably 0.3 or more, more preferably 0.5 or more, and of which the expression magnification is preferably 3 or more, more preferably 5 or more.

	Number	Date	Country
Parent	10487439	May 2004	US
Child	11772057	Jun 2007	US

PROCESSES FOR DETECTING TOXIC SUBSTANCES

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