Claims
- 1. A process for preparing a compound of the formula (I'): ##STR185## wherein Ar is a substituted phenyl group: R.sup.1 and R.sup.2 independently are a hydrogen atom or a lower alkyl group, or R.sup.1 and R.sup.2 may combine together to form a lower alkylene group; R.sup.3 is an optionally substituted aliphatic or aromatic hydrocarbon residue or an optionally substituted aromatic heterocyclic group; X is a nitrogen atom or a methine group; and Y and Z independently are a nitrogen atom or a methine group which may optionally be substituted with a lower alkyl group, or a salt thereof, which is characterized by reacting a compound represented by the formula (II): ##STR186## wherein the symbols have the same meanings as defined in the formula (I'), with a compound represented by the formula (III): ##STR187## wherein the symbols have the same meanings as defined in the formula (I') in a solvent selected from the group consisting of sulfoxides, amides and ureylenes in the presence of a base selected from the group consisting of alkali metal hydrides, alkali metal carbonates and tetrabutylammonium fluoride.
- 2. A process for preparing a compound of formula (I'): ##STR188## wherein Ar is a substituted phenyl group; R.sup.1 and R.sup.2 independently are a hydrogen atom or a lower alkyl group, or R.sup.1 and R.sup.2 may combine together to form a lower alkylene group; R.sup.3 is an optionally substituted aliphatic or aromatic hydrocarbon residue or an optionally substituted aromatic heterocyclic group; X is a nitrogen atom or a methine group; and Y and Z independently are a nitrogen atom or a methine group which may optionally be substituted with a lower alkyl group, or a salt thereof, which is characterized by reacting a compound represented by the formula (IV): ##STR189## wherein the symbols have the same meanings as defined in the formula (I'), or a salt thereof, with a compound represented by the formula (V): ##STR190## wherein the symbols have the same meanings as defined in the formula (I') in a solvent selected from the group consisting of sulfoxides, amides and ureylenes in the presence of a base selected from the group consisting of alkali metal hydrides, alkali metal carbonates and tetrabutylammonium fluoride.
Priority Claims (2)
Number |
Date |
Country |
Kind |
4-110400 |
Apr 1992 |
JPX |
|
5-022623 |
Feb 1993 |
JPX |
|
Parent Case Info
This application is a divisional of Ser. No. 08/053,239 filed Apr. 28, 1993, now U.S. Pat. No. 5,371,181.
Divisions (1)
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Number |
Date |
Country |
Parent |
53239 |
Apr 1993 |
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