PRODUCTION OF HLA MONOCLONAL ANTIBODIES BY B CELL LINES

Information

• Research Project
• 3596257

• ApplicationId

  3596257

• Core Project Number

  N43AI072668

• Full Project Number

  N43AI072668-000

• Serial Number

  72668

• FOA Number

• Sub Project Id

• Project Start Date

  6/25/1987 - 37 years ago

• Project End Date

  -

• Program Officer Name

• Budget Start Date

  6/25/1987 - 37 years ago

• Budget End Date

  12/24/1987 - 37 years ago

• Fiscal Year

  1987

• Support Year

• Suffix

• Award Notice Date

  -

Organizations

• FAST SYSTEMS LTD

This contract is for the production of monoclonal antibodies against epitopes of the D/DR region of the major histocompatibility complex using EBV transformed B cell lines. The initial work will be done in Genova, Italy under the direction of Dr. G. B. Ferrara who has pioneered research in this area. The antibodies produced by these B cell lines will be characterized for specificity by conventional microcytotoxicity and flow cytometry methodologies. The antibodies identified and acquired will facilitate immunogenetic research such as the relationship between disease susceptibility and the MHC and the improvement of matching for transplantation.

IC Name

• Activity

  N43

• Administering IC

  AI

• Application Type

  1

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  855

• Ed Inst. Type

• Funding ICs

• Funding Mechanism

• Study Section

• Study Section Name

• Organization Name

  FAST SYSTEMS, INC.

• Organization Department

• Organization DUNS

• Organization City

  GAITHERSBURG

• Organization State

  MD

• Organization Country

  UNITED STATES

• Organization Zip Code

  20878

• Organization District

  UNITED STATES