Project 2: Prevention of Opioid Overdose following Incarceration Leveraging Mobile Health Technology

Information

  • Research Project
  • 10259150
  • ApplicationId
    10259150
  • Core Project Number
    P20GM125507
  • Full Project Number
    5P20GM125507-04
  • Serial Number
    125507
  • FOA Number
    PAR-16-415
  • Sub Project Id
    8299
  • Project Start Date
    9/1/2018 - 5 years ago
  • Project End Date
    8/31/2023 - 9 months ago
  • Program Officer Name
    JUSTINOVA, ZUZANA
  • Budget Start Date
    9/1/2021 - 2 years ago
  • Budget End Date
    8/31/2022 - a year ago
  • Fiscal Year
    2021
  • Support Year
    04
  • Suffix
  • Award Notice Date
    9/16/2021 - 2 years ago
Organizations

Project 2: Prevention of Opioid Overdose following Incarceration Leveraging Mobile Health Technology

Project Summary/Abstract Fatal opioid overdoses have increased dramatically over the past decade. Incarcerated men and women with a history of opioid use are at high-risk for overdose upon re-entry into the community. Effective methods of overdose prevention and linkage to community-based substance use treatment post-incarceration are needed. The criminal justice setting is an ideal location to implement opioid overdose prevention interventions due to the high rates of at-risk populations and the opportunities for education and intervention upon re-entry into the community. However, this setting poses significant structural barriers to implementing and sustaining interventions. The use of mobile technology offers an innovative approach to overcoming these barriers and preventing opioid overdose among at-risk men and women upon re-entry into the community post-incarceration. This study will be a Stage I pilot and feasibility study that will be the first to use mobile technology tools to prevent opioid overdose following incarceration. The proposed study seeks to develop and test two mobile platforms: (a) mobile health application intervention (MAI); and (b) text messaging intervention (SMS) and will compare them to standard of care (SOC). Both interventions will use motivational interviewing and harm reduction skills training prior to release from incarceration. The proposed method of opioid overdose prevention is expected to be an efficient and easily disseminable platform that will facilitate linkage to community-based resources, increase knowledge and behavioral skills regarding opioid overdose prevention, and prevent the occurrence of opioid overdose among a key population during a particularly vulnerable period of time. A three-phase, top-down research approach to adapt, refine, and pilot test the interventions will be conducted. Phase 1 will include individual interviews (IDIs) with the target population and key stakeholders in the criminal justice setting to inform intervention development and the implementation strategy. Phase 2 will include development of the mobile intervention technologies. We will conduct a beta test and a series of IDIs with the target population and key stakeholders to inform iterative revision of the interventions. During Phase 3, we will evaluate the feasibility, acceptability, and preliminary efficacy of the mobile technology tools among men and women at-risk for opioid overdose upon re-entry into the community post-incarceration via a 3-armed (MAI vs. SMS vs. SOC) randomized controlled trial with 90 participants. Data will be collected regarding recent drug use, overdose risk behaviors, and linkage to community-based substance use services at 1-, 3-, 6- and 12-month follow-ups. Through IDIs, we will explore: (1) the difference between individuals who demonstrate high usage patterns of the intervention technologies and those with low usage patterns; (2) barriers and facilitators related to implementation and sustainability within the criminal justice setting; and (3) the relationship between outcomes and usage of the intervention technologies. The project is significant in regards to its potential to prevent opioid overdose among criminal justice populations and gain greater understanding of the utility of two mhealth intervention modalities.

IC Name
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
  • Activity
    P20
  • Administering IC
    GM
  • Application Type
    5
  • Direct Cost Amount
    64563
  • Indirect Cost Amount
    7077
  • Total Cost
  • Sub Project Total Cost
    71640
  • ARRA Funded
    False
  • CFDA Code
  • Ed Inst. Type
  • Funding ICs
    NIGMS:71640\
  • Funding Mechanism
    RESEARCH CENTERS
  • Study Section
    ZGM1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    RHODE ISLAND HOSPITAL
  • Organization Department
  • Organization DUNS
    075710996
  • Organization City
    PROVIDENCE
  • Organization State
    RI
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    029034923
  • Organization District
    UNITED STATES