Claims
- 1. A prostaglandin derivative represented by formula ##STR6## (wherein R.sup.1 represents a hydrogen atom or a C.sub.1 -C.sub.6 alkyl group, and R.sup.2 represents a cyclohexyl group or a cyclopentylmethyl group), and a salt thereof.
- 2. A drug containing a compound of formula (I) set forth in claim 1 or a pharmaceutically acceptable salt thereof.
- 3. An agent for inhibition of platelet aggregation, containing a compound of formula (I) set forth in claim 1 or a pharmaceutically acceptable salt thereof.
- 4. An agent for treatment of renal failure and diseases of circulatory organs, containing a compound of formula (I) set forth in claim 1 or a pharmaceutically acceptable salt thereof.
- 5. A pharmaceutical composition containing a compound of formula (I) set forth in claim 1 or a pharmaceutically acceptable salt thereof and pharmaceutically acceptable additives.
- 6. A method for treatment of renal failure or diseases of circulatory organs in mammals, which comprises administering, to a mammal, an effective amount of a compound of formula (I) set forth in claim 1 or a pharmaceutically acceptable salt thereof.
Priority Claims (1)
Number |
Date |
Country |
Kind |
4-282001 |
Oct 1992 |
JPX |
|
Parent Case Info
This application is a 371 of PCT/JP93/01493 filed Oct. 18, 1993.
PCT Information
Filing Document |
Filing Date |
Country |
Kind |
102e Date |
371c Date |
PCT/JP93/01493 |
10/18/1993 |
|
|
4/19/1995 |
4/19/1995 |
Publishing Document |
Publishing Date |
Country |
Kind |
WO94/08959 |
4/28/1994 |
|
|
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4029681 |
Smith |
Jun 1977 |
|
Foreign Referenced Citations (3)
Number |
Date |
Country |
0299914 |
Jul 1988 |
EPX |
52-100446 |
Aug 1977 |
JPX |
2502009 |
Jul 1990 |
JPX |
Non-Patent Literature Citations (4)
Entry |
J. Org. Chem vol. 53, p. 5590 (1988). |
Tetrahedron Lett, vol. 30, p. 7083 (1989). |
Tsuchida et al, Arzneim-Forsch, vol. 36 p. 1745, 1986. |
Handbook of Physiology (Sec. 8 Renal Physiology) p. 103, 1973. |