Claims
- 1. A prostenoic acid compound of the formula ##STR11## wherein R.sup.1 is H or alkyl of 1-4 carbon atoms;
- R.sup.2 is alkyl of 5-9 carbon atoms;
- A is CH.sub.2 D or CH.dbd.C(OR.sup.5);
- D is carbonyl or dialkoxypolymethylene of up to 7 carbon atoms;
- R.sup.5 is alkanoyl, alkenoyl, alkynoyl, alkylsulfonyl, alkanoyl substituted by fluorine, chlorine or bromine, each of up to 4 carbon atoms, sulfo or the acyl radical of phosphoric acid;
- R.sup.4 is H or R.sup.5 ; and metal or ammonium salts thereof.
- 2. A compound of claim 1, wherein R.sup.1 is H or ethyl.
- 3. A compound of claim 1, wherein R.sup.2 is pentyl, 1-methylpentyl or 1,1-dimethylpentyl.
- 4. A compound of claim 1, wherein A is 2-oxoethylene-1,2 2,2-ethylenedioxyethylene-1,2 or 2-acetoxyvinylene-1,2.
- 5. A compound of claim 1, wherein R.sup.1 is H or ethyl and R.sup.2 is pentyl, 1-methylpentyl or 1,1-dimethylpentyl.
- 6. 9.beta.-hydroxy-15,15-ethylenedioxy-12-prostenoic acid ethyl ester, a compound of claim 1.
- 7. 9.beta.-hydroxy-15,15-ethylenedioxy-16-methyl-12-prostenoic acid ethyl ester, a compound of claim 1.
- 8. An anti-thrombotic composition which comprises an anti-thrombotically effective amount of a compound of claim 1 and a pharmaceutically acceptable adjuvant.
Priority Claims (1)
Number |
Date |
Country |
Kind |
2455976 |
Nov 1974 |
DE |
|
Parent Case Info
This is a continuation-in-part of application Ser. No. 634,349, filed Nov. 24, 1975.
Non-Patent Literature Citations (1)
Entry |
technology and Assessment and Forecast, 7th report Patent and Trademark Office, pp. 81-88, (1977). |
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
634349 |
Nov 1975 |
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