Lee et al., Genome Research (1998) 8:1022-1037.* |
Moore et al., J. Mol. Biol., 292:797-817 (1999). |
Alpers, “Epidemiology and Ecology of Kuru,” Slow Transmissible Diseases of the Nervous System, vol. 1, S.B. Prusiner and W.J. Hadlow, eds. (New York: Academic Press), pp. 66-90 (1979). |
Basler et al., “Scrapie and Cellular PrP Isoforms Are Encoded by the Same Chromosomal Gene,” Cell, (Aug. 1, 1989), 46:417-28. |
Billeter, et al., “Prion Protein NMR Structure and Species Barrier for Prion Diseases,” Proc. Natl. Acad. Sci. USA (Jul. 1997), 94:7281-7285. |
Bolton et al., “Identification of a Protein That Purifies with the Scrapie Prion,” Science (Dec. 24, 1982) 218:1309-11 (1982). |
Brown et al., “Friendly Fire” in Medicine: Hormones, Homografts, and Creutzfeldt-Jakob Disease, Lancet (Jul. 4, 1992) 340:24-27. |
Chazot, et al., “New Variant of Creutzfeldt-Jakob disease in a 2-year-old French Man,” Lancet (Apr. 27, 1996) 347(9009):1181. |
Donne et al., “Structure of the Recombinant Full-Length Hamster Prion Protein PrP (29-231): The N Terminus is Highly Flexible,” Proc. Natl. Acad. Sci. USA (Dec. 1997) 94:13452-13457. |
Gajdusek et al., “Experimental Transmission of a Kuru-Like Syndrome to Chimpanzees,” Nature (Feb. 19, 1966) 209(5025);794-796. |
Gajdusek, “Unconventional Viruses and the Origin and Disappearance of Kuru” Science (Sep. 2, 1977), 197(4307):943-960. |
Gibbs, Jr., et al., “Creutzfeldt-Jakob Disease (Spongiform Encephalopathy): Transmission to the Chimpanzee,” Science (Jul. 1968), 161:388-389. |
Gibbs, Jr., et al., “Strain Variation in the Viruses of Creutzfeldt-Jakob Disease and Kuru,” Slow Transmissible Diseases of the Nervous System, vol. 2, S.B. Prusiner and W.J. Hadlow, eds. (New York: Academic Press), pp.87-110 (1979). |
Goldfarb et al., Fatal Familial Insomnia and Familial Creutzfeldt-Jakob Disease: Disease Phenotype Determined by a DNA Polymorphism, Science, (Oct. 30, 1992) 258:806-808. |
Hadlow, “Scrapie and Kuru,” Lancet (Sep. 5, 1959), 2:289-290. |
Harries-Jones et al., “Creutzfeldt-Jakob Disease in England and Wales, 1980-1984: a Case-Control Study of Potential Risk Factors,” J. Neurol. Neurosurg. Psychiatry (1988) 51:1113-1119. |
Hsiao et al., “Inherited Human Prion Diseases,” Neurology (Dec. 1990), 40:1820-1827. |
James et al., “Solution Structure of a 142-Residue Recombinant Prion Protein Corresponding to the Infectious Fragment of the Scrapie Isoform,” Proc. Natl. Acad. Sci. USA (Sep. 1997), 94:10086-10091. |
Kitamoto et al., “Human Prion Diseases With Variant Prin Protein,” Phil. Trans. R. Soc. Lond. B, (1994) 343:391-398. |
Klatzo et al., “Pathology of Kuru,” Laboratory Investigation, (Jul./Aug. 1959) 8(4):799-847. |
McKinley et al., “A Protease-Resistant Protein Is a Structural Component of the Scrapie Prion,” Cell (Nov. 1983) 35:57-62. |
Medori et al., Fatal Familial Insomnia, A Prion Disease With a Mutation at Codon 178 of The Prion Protein Gene, New. England Journal of Medicine, (Feb. 13, 1992), 326(7):444-449. |
Peretz et al., “A Conformational Transition at the N-terminus of the Prion Protein Features in Formation of the Scrapie Isoform,” Journal of Molecular Biology, (1997). 273:614-622. |
Prusiner et al., “Further Purification and Characterization of Scrapie Prions,” Biochemistry (1982), 21(26):6942-50. |
Prusiner, et al., “Purification and Structural Studies of a Major Scrapie Prion Protein,” Cell (Aug. 1984), 38:127-134. |
Prusiner, “Molecular Biology of Prion Disease,” Science (Jun. 14, 1991), 252:1515-1522. |
Rogers, et al., “Conversion of Truncated and Elongated Prion Proteins into the Scrapie Isoform in Cultured Cells,” Proc. Natl. Acad. Sci. USA (Apr. 1993), 90:3182-3186. |
Tateishi et al., “Prion Protein Gene Analysis and Transmission Studies of Creutzfeldt-Jakob Disease,”, Prion Diseases of Humans and Animals, Prusiner et al., (London: Ellis Horwood), (1992) pp. 129-134. |
Telling, et al., Prion Propagaton in Mice Expressing Human and Chimeric PrP Transgenes Implicates the Interaction of Cellular PrP with Another Protein, Cell (Oct. 6, 1995), 83:79-90. |
Telling et al., “Evidence for the Conformation of the Pathologic Isoform of the Prion Protein Enciphering and Propagating Prion Diversity,” Science (Dec. 20, 1996), 274:2079-2082. |
Wilesmith, et al., “Bovine Spongiform Encephalopathy,” Current Topics in Microbiology an Immunology, (1991) 172:21-38. |
Will, et al., “A New Variant of Creutzfeldt-Jakob Disease in the UK,” Lancet (Apr. 6, 1996), 347:921-925. |