Claims
- 1. .gamma.-[4-(3-Trifluoromethylphenyl)-4-hydroxypiperidino]-2-hydroxy-4-fluorobutyrophenone, or a pharmaceutically acceptable acid addition salt thereof.
- 2. .gamma.-[4-(2-Keto-1-benzimidazolinyl)piperidin-1-yl]-2-hydroxy-4-fluorobutyrophenone, or a pharmaceutically acceptable acid addition salt thereof.
- 3. .gamma.-[4-Oxo-1-phenyl-1,3,8-triazaspiro[4,5]-decan-8-yl]-2-hydroxy-4-fluorobutyrophenone, or a pharmaceutically acceptable acid addition salt thereof.
- 4. An antipsychotic composition comprising an effective antipsychotic amount of at least one of the compounds as claimed in any one of claims 1, 2 or 3 or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable diluent or carrier.
- 5. A method of treating a patient suffering from mental disease which comprises administering to said patient an effective psychotropic amount of a compound according to any one of claims 1, 2 or 3.
- 6. The method according to claim 5, wherein from 1 to 200 mg. of said compound is administered orally to the patient daily.
Priority Claims (2)
Number |
Date |
Country |
Kind |
50/27489 |
Mar 1975 |
JPX |
|
50/138836 |
Nov 1975 |
JPX |
|
Parent Case Info
This application is a continuation of copending application Ser. No. 663,763, filed on Mar. 4, 1976, now abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
3799932 |
Yamamoto et al. |
Mar 1974 |
|
3979390 |
Sasajima et al. |
Sep 1976 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
47-18878 |
Sep 1972 |
JPX |
Non-Patent Literature Citations (1)
Entry |
Janssen, P., Int. J. Neuropharmacol., 1962, 1, 145-148. |
Continuations (1)
|
Number |
Date |
Country |
Parent |
663763 |
Mar 1976 |
|